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UA118646C2 - Виділене антитіло, яке специфіічно зв'язується з онкостатином м (оm) людини - Google Patents

Виділене антитіло, яке специфіічно зв'язується з онкостатином м (оm) людини

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Publication number
UA118646C2
UA118646C2 UAA201305880A UAA201305880A UA118646C2 UA 118646 C2 UA118646 C2 UA 118646C2 UA A201305880 A UAA201305880 A UA A201305880A UA A201305880 A UAA201305880 A UA A201305880A UA 118646 C2 UA118646 C2 UA 118646C2
Authority
UA
Ukraine
Prior art keywords
human
antibodies
methods
antibody
relates
Prior art date
Application number
UAA201305880A
Other languages
English (en)
Inventor
Хуан Карлос Альмагро
Уілльям Дабелл
Йохан Франссон
Хосе Пардінас
Original Assignee
Янссен Байотек, Інк.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
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Application filed by Янссен Байотек, Інк. filed Critical Янссен Байотек, Інк.
Publication of UA118646C2 publication Critical patent/UA118646C2/uk

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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/395—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/24—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against cytokines, lymphokines or interferons
    • C07K16/244—Interleukins [IL]
    • C07K16/248—IL-6
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
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    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
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    • C—CHEMISTRY; METALLURGY
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    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/20—Immunoglobulins specific features characterized by taxonomic origin
    • C07K2317/21—Immunoglobulins specific features characterized by taxonomic origin from primates, e.g. man
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    • C07K2317/30—Immunoglobulins specific features characterized by aspects of specificity or valency
    • C07K2317/33—Crossreactivity, e.g. for species or epitope, or lack of said crossreactivity
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Abstract

Винахід стосується виділеного антитіла, яке специфічно зв’язується з онкостатином М (ОМ) людини, його антигензв’язувального фрагмента, виділеного полінуклеотиду, що кодує важкий та легкий ланцюг антитіла, стабільно трансформованої або трансфікованої рекомбінантної клітини-хазяїна, способу одержання антитіла, набору, що містить стерильний препарат виділеного антитіла та фармацевтичної композиції. Винахід також стосується способу лікування хворої людини, що страждає на захворювання або розлад, пов’язаний з моделюючою активністю або взаємодією людського ОМ з людським білком gp130.
UAA201305880A 2010-10-13 2011-10-10 Виділене антитіло, яке специфіічно зв'язується з онкостатином м (оm) людини UA118646C2 (uk)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US39268310P 2010-10-13 2010-10-13
PCT/US2011/055606 WO2012051111A2 (en) 2010-10-13 2011-10-10 Human oncostatin m antibodies and methods of use

Publications (1)

Publication Number Publication Date
UA118646C2 true UA118646C2 (uk) 2019-02-25

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ID=45934343

Family Applications (1)

Application Number Title Priority Date Filing Date
UAA201305880A UA118646C2 (uk) 2010-10-13 2011-10-10 Виділене антитіло, яке специфіічно зв'язується з онкостатином м (оm) людини

Country Status (21)

Country Link
US (5) US20120093833A1 (uk)
EP (1) EP2627356B1 (uk)
JP (3) JP6216917B2 (uk)
KR (1) KR101920250B1 (uk)
CN (1) CN103261223B (uk)
AR (2) AR083418A1 (uk)
AU (1) AU2011313847B2 (uk)
BR (1) BR112013009083B1 (uk)
CA (1) CA2814652C (uk)
EA (1) EA031044B1 (uk)
IL (1) IL225573B (uk)
JO (1) JO3496B1 (uk)
MX (2) MX392780B (uk)
PH (1) PH12013500703A1 (uk)
RU (1) RU2600444C2 (uk)
SG (2) SG189322A1 (uk)
TW (1) TWI548749B (uk)
UA (1) UA118646C2 (uk)
UY (1) UY33670A (uk)
WO (1) WO2012051111A2 (uk)
ZA (1) ZA201303429B (uk)

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EP3197480A1 (en) * 2014-09-24 2017-08-02 Universita' Degli Studi Di Padova Composition to induce bone marrow stem cell mobilization
CN104258396A (zh) * 2014-09-29 2015-01-07 武汉大学 Ⅱ型抑瘤素m受体在治疗动脉粥样硬化中的功能和应用
WO2016120625A1 (en) 2015-01-29 2016-08-04 Isis Innovation Limited Biomarker
BR112018012344A2 (pt) * 2015-12-17 2018-12-04 Janssen Biotech Inc anticorpos que se ligam especificamente a hla-dr e seus usos
GB201614627D0 (en) * 2016-08-30 2016-10-12 Glaxosmithkline Ip Dev Ltd Antigen binding proteins
EP3558363A1 (en) 2016-12-21 2019-10-30 Amgen Inc. Anti-tnf alpha antibody formulations
WO2019084307A1 (en) * 2017-10-26 2019-05-02 Celldex Therapeutics, Inc. ANTI-MERTK ANTIBODIES AND METHODS OF USE
FR3090637A1 (fr) * 2018-12-21 2020-06-26 Universite De Poitiers Protéine de liaison spécifique capable de se lier spécifiquement à l’oncostatine M humaine (hOSM) et ses utilisations.
CN109884320A (zh) * 2019-03-29 2019-06-14 重庆医科大学 抑瘤素m作为生物标志物在制备脓毒症诊断试剂中的应用
US11633457B2 (en) 2019-04-11 2023-04-25 Boise State University Pharmaceutical compositions comprising oncostatin m (OSM) antagonist derivatives and methods of use
EP3955040A4 (en) 2019-04-12 2022-03-30 Sumitomo Electric Industries, Ltd. FIBER OPTIC RIBBON, MOLD AND METHOD FOR PRODUCTION OF FIBER OPTIC RIBBON
KR20230092978A (ko) 2020-10-19 2023-06-26 조에티스 서비시즈 엘엘씨 개 및 고양이 온코스타틴 m 수용체 베타에 대한 항체 및 이의 용도
CN118909077A (zh) * 2024-10-10 2024-11-08 江苏凯基生物技术股份有限公司 一种抑瘤素m的制备方法

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