UA100699C2 - Antibody to human cd20 and using thereof for the treatment cd20-mediated disease or condition - Google Patents
Antibody to human cd20 and using thereof for the treatment cd20-mediated disease or conditionInfo
- Publication number
- UA100699C2 UA100699C2 UAA201002186A UAA201002186A UA100699C2 UA 100699 C2 UA100699 C2 UA 100699C2 UA A201002186 A UAA201002186 A UA A201002186A UA A201002186 A UAA201002186 A UA A201002186A UA 100699 C2 UA100699 C2 UA 100699C2
- Authority
- UA
- Ukraine
- Prior art keywords
- antibody
- human
- treatment
- condition
- mediated disease
- Prior art date
Links
- 201000010099 disease Diseases 0.000 title abstract 2
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 title abstract 2
- 230000001404 mediated effect Effects 0.000 title abstract 2
- 239000000427 antigen Substances 0.000 abstract 2
- 102000036639 antigens Human genes 0.000 abstract 2
- 108091007433 antigens Proteins 0.000 abstract 2
- 230000004540 complement-dependent cytotoxicity Effects 0.000 abstract 2
- 239000012634 fragment Substances 0.000 abstract 2
- 208000010839 B-cell chronic lymphocytic leukemia Diseases 0.000 abstract 1
- 102100022005 B-lymphocyte antigen CD20 Human genes 0.000 abstract 1
- 208000011231 Crohn disease Diseases 0.000 abstract 1
- 101000897405 Homo sapiens B-lymphocyte antigen CD20 Proteins 0.000 abstract 1
- 101100495232 Homo sapiens MS4A1 gene Proteins 0.000 abstract 1
- 208000031422 Lymphocytic Chronic B-Cell Leukemia Diseases 0.000 abstract 1
- 208000015914 Non-Hodgkin lymphomas Diseases 0.000 abstract 1
- 208000037976 chronic inflammation Diseases 0.000 abstract 1
- 208000037893 chronic inflammatory disorder Diseases 0.000 abstract 1
- 208000032852 chronic lymphocytic leukemia Diseases 0.000 abstract 1
- 230000001939 inductive effect Effects 0.000 abstract 1
- 206010039073 rheumatoid arthritis Diseases 0.000 abstract 1
- 201000000596 systemic lupus erythematosus Diseases 0.000 abstract 1
Landscapes
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Abstract
The invention relates to human antibody or antigen-binding fragment thereof that specifically binds to human CD20 and is capable of inducing complement dependent cytotoxicity (CDC). The invention further relates to use of antibody or antigen-binding fragment thereof for the treatment of CD20-mediated disease or condition, for example, non-Hodgkin's lymphoma, rheumatoid arthritis, systemic lupus erythematosus, Crohn's disease, chronic lymphocytic leukemia, and inflammatory diseases.
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US96281107P | 2007-07-31 | 2007-07-31 | |
| PCT/US2008/071709 WO2009018411A1 (en) | 2007-07-31 | 2008-07-31 | Human antibodies to human cd20 and method of using thereof |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| UA100699C2 true UA100699C2 (en) | 2013-01-25 |
Family
ID=51584484
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| UAA201002186A UA100699C2 (en) | 2007-07-31 | 2008-07-31 | Antibody to human cd20 and using thereof for the treatment cd20-mediated disease or condition |
Country Status (1)
| Country | Link |
|---|---|
| UA (1) | UA100699C2 (en) |
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US12030952B2 (en) | 2015-10-02 | 2024-07-09 | Hoffmann-La Roche Inc. | Bispecific anti-human CD20/human transferrin receptor antibodies and methods of use |
| US12252533B2 (en) | 2015-06-24 | 2025-03-18 | Hoffmann-La Roche Inc. | Anti-transferrin receptor antibodies with tailored affinity |
-
2008
- 2008-07-31 UA UAA201002186A patent/UA100699C2/en unknown
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US12252533B2 (en) | 2015-06-24 | 2025-03-18 | Hoffmann-La Roche Inc. | Anti-transferrin receptor antibodies with tailored affinity |
| US12030952B2 (en) | 2015-10-02 | 2024-07-09 | Hoffmann-La Roche Inc. | Bispecific anti-human CD20/human transferrin receptor antibodies and methods of use |
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