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UA106617C2 - N- (hetero) arylpyrrolidine derivatives of pirazol-4-ylpyrrolo [2,3-d] pyrimidines and pyrrol-3-ylpyrrolo [2,3-d] pyrimidines as inhibitors - Google Patents

N- (hetero) arylpyrrolidine derivatives of pirazol-4-ylpyrrolo [2,3-d] pyrimidines and pyrrol-3-ylpyrrolo [2,3-d] pyrimidines as inhibitors

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Publication number
UA106617C2
UA106617C2 UAA201115198A UAA201115198A UA106617C2 UA 106617 C2 UA106617 C2 UA 106617C2 UA A201115198 A UAA201115198 A UA A201115198A UA A201115198 A UAA201115198 A UA A201115198A UA 106617 C2 UA106617 C2 UA 106617C2
Authority
UA
Ukraine
Prior art keywords
ylpyrrolo
pyrimidines
inhibitors
arylpyrrolidine
hetero
Prior art date
Application number
UAA201115198A
Other languages
Ukrainian (uk)
Inventor
Джеймс Д. Роджерс
Стейсі Шепард
Аргіріос Г. Арванітіс
Хайшен Ван
Льюіс Сторейс
Беверлі Фолмер
Лісінь Шао
Веньюй Чжу
Джозеф П. Гленн
Original Assignee
Інсайт Корпорейшн
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=47780587&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=UA106617(C2) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Інсайт Корпорейшн filed Critical Інсайт Корпорейшн
Priority claimed from PCT/US2010/035783 external-priority patent/WO2010135650A1/en
Publication of UA106617C2 publication Critical patent/UA106617C2/en

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  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)

Abstract

Цей винахід стосується N-(гетеро)арилпіролідинових похідних Формули І:, Іщо є JAK-інгібіторами, такими як селективні інгібітори JAK1, що застосовують для лікування захворювань, пов'язаних з активністю Янус-кіназ, включаючи, наприклад, запальні й аутоімунні розлади, а також рак.The present invention relates to N- (hetero) arylpyrrolidine derivatives of Formula I :, What are JAK inhibitors, such as selective JAK1 inhibitors, for use in the treatment of diseases related to Janus kinase activity, including, for example, inflammatory and autoimmune disorders, as well as cancer.

UAA201115198A 2009-05-22 2010-05-21 N- (hetero) arylpyrrolidine derivatives of pirazol-4-ylpyrrolo [2,3-d] pyrimidines and pyrrol-3-ylpyrrolo [2,3-d] pyrimidines as inhibitors UA106617C2 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US18062209P 2009-05-22 2009-05-22
PCT/US2010/035783 WO2010135650A1 (en) 2009-05-22 2010-05-21 N-(HETERO)ARYL-PYRROLIDINE DERIVATIVES OF PYRAZOL-4-YL-PYRROLO[2,3-d]PYRIMIDINES AND PYRROL-3-YL-PYRROLO[2,3-d]PYRIMIDINES AS JANUS KINASE INHIBITORS

Publications (1)

Publication Number Publication Date
UA106617C2 true UA106617C2 (en) 2014-09-25

Family

ID=47780587

Family Applications (1)

Application Number Title Priority Date Filing Date
UAA201115198A UA106617C2 (en) 2009-05-22 2010-05-21 N- (hetero) arylpyrrolidine derivatives of pirazol-4-ylpyrrolo [2,3-d] pyrimidines and pyrrol-3-ylpyrrolo [2,3-d] pyrimidines as inhibitors

Country Status (2)

Country Link
EC (1) ECSP11011535A (en)
UA (1) UA106617C2 (en)

Also Published As

Publication number Publication date
ECSP11011535A (en) 2012-01-31

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