UA106458C2 - Чутливий до сульфонілсечовини репресорний білок - Google Patents
Чутливий до сульфонілсечовини репресорний білокInfo
- Publication number
- UA106458C2 UA106458C2 UAA201312853A UAA201312853A UA106458C2 UA 106458 C2 UA106458 C2 UA 106458C2 UA A201312853 A UAA201312853 A UA A201312853A UA A201312853 A UAA201312853 A UA A201312853A UA 106458 C2 UA106458 C2 UA 106458C2
- Authority
- UA
- Ukraine
- Prior art keywords
- sulfonylurea
- polypeptide
- repressor protein
- responsive repressor
- polynucleotide
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/195—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
- C07K14/24—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Enterobacteriaceae (F), e.g. Citrobacter, Serratia, Proteus, Providencia, Morganella, Yersinia
- C07K14/245—Escherichia (G)
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/195—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
- C12N15/635—Externally inducible repressor mediated regulation of gene expression, e.g. tetR inducible by tetracyline
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
- C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
- C12N15/82—Vectors or expression systems specially adapted for eukaryotic hosts for plant cells, e.g. plant artificial chromosomes (PACs)
- C12N15/8216—Methods for controlling, regulating or enhancing expression of transgenes in plant cells
- C12N15/8217—Gene switch
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
- C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
- C12N15/82—Vectors or expression systems specially adapted for eukaryotic hosts for plant cells, e.g. plant artificial chromosomes (PACs)
- C12N15/8216—Methods for controlling, regulating or enhancing expression of transgenes in plant cells
- C12N15/8237—Externally regulated expression systems
- C12N15/8238—Externally regulated expression systems chemically inducible, e.g. tetracycline
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
- C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
- C12N15/82—Vectors or expression systems specially adapted for eukaryotic hosts for plant cells, e.g. plant artificial chromosomes (PACs)
- C12N15/8241—Phenotypically and genetically modified plants via recombinant DNA technology
- C12N15/8261—Phenotypically and genetically modified plants via recombinant DNA technology with agronomic (input) traits, e.g. crop yield
- C12N15/8271—Phenotypically and genetically modified plants via recombinant DNA technology with agronomic (input) traits, e.g. crop yield for stress resistance, e.g. heavy metal resistance
- C12N15/8274—Phenotypically and genetically modified plants via recombinant DNA technology with agronomic (input) traits, e.g. crop yield for stress resistance, e.g. heavy metal resistance for herbicide resistance
- C12N15/8278—Sulfonylurea
Landscapes
- Health & Medical Sciences (AREA)
- Genetics & Genomics (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Molecular Biology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Biotechnology (AREA)
- General Engineering & Computer Science (AREA)
- Biomedical Technology (AREA)
- Wood Science & Technology (AREA)
- Zoology (AREA)
- Biophysics (AREA)
- General Health & Medical Sciences (AREA)
- Biochemistry (AREA)
- Physics & Mathematics (AREA)
- Microbiology (AREA)
- Plant Pathology (AREA)
- Cell Biology (AREA)
- Gastroenterology & Hepatology (AREA)
- Medicinal Chemistry (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- General Chemical & Material Sciences (AREA)
- Peptides Or Proteins (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
Abstract
Винахід належить до ізольованого поліпептиду, який включає чутливий до сульфонілсечовини репресор, що специфічно зв'язується з полінуклеотидом, який включає послідовність оператора, де зв'язування регулюється сполукою сульфонілсечовини, і причому зазначений поліпептид включає амінокислотну послідовність, яка має принаймні 90 % ідентичності послідовності до SEQ ID NO: 1233. Винахід також належить до способу регуляції транскрипції полінуклеотиду, який представляє інтерес, у клітині-хазяїні із застосуванням зазначеного поліпептида.
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US10891708P | 2008-10-28 | 2008-10-28 | |
| UAA201106478A UA105017C2 (uk) | 2008-10-28 | 2009-10-22 | Чутливі до сульфонілсечовини репресорні білки |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| UA106458C2 true UA106458C2 (uk) | 2014-08-26 |
Family
ID=42026787
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| UAA201312853A UA106458C2 (uk) | 2008-10-28 | 2009-10-22 | Чутливий до сульфонілсечовини репресорний білок |
| UAA201106478A UA105017C2 (uk) | 2008-10-28 | 2009-10-22 | Чутливі до сульфонілсечовини репресорні білки |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| UAA201106478A UA105017C2 (uk) | 2008-10-28 | 2009-10-22 | Чутливі до сульфонілсечовини репресорні білки |
Country Status (9)
| Country | Link |
|---|---|
| US (7) | US8257956B2 (uk) |
| EP (1) | EP2364322A1 (uk) |
| CN (1) | CN102264758B (uk) |
| CA (1) | CA2740147A1 (uk) |
| MX (1) | MX2011003766A (uk) |
| RU (1) | RU2532854C2 (uk) |
| UA (2) | UA106458C2 (uk) |
| WO (1) | WO2010062518A1 (uk) |
| ZA (1) | ZA201102495B (uk) |
Families Citing this family (16)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP2364322A1 (en) | 2008-10-28 | 2011-09-14 | Pioneer Hi-Bred International Inc. | Sulfonylurea-responsive repressor proteins |
| RU2012149891A (ru) * | 2010-04-23 | 2014-05-27 | Пайонир Хай-Бред Интернэшнл, Инк. | Композиции переключения генов и способы их применения |
| US20140173775A1 (en) | 2012-12-13 | 2014-06-19 | Pioneer Hi-Bred International, Inc. | Methods and compositions for producing and selecting transgenic plants |
| US20160152995A1 (en) * | 2013-03-11 | 2016-06-02 | Pioneer Hi-Bred International, Inc. | Methods and compositions to improve the spread of chemical signals in plants |
| CN105473721A (zh) * | 2013-03-11 | 2016-04-06 | 先锋国际良种公司 | 采用磺酰脲类依赖型稳定化结构域的方法和组合物 |
| CN120574876A (zh) | 2013-08-22 | 2025-09-02 | 纳幕尔杜邦公司 | 使用向导rna/cas内切核酸酶系统的植物基因组修饰及其使用方法 |
| EP3365439A1 (en) | 2015-10-20 | 2018-08-29 | Pioneer Hi-Bred International, Inc. | Methods and compositions for marker-free genome modification |
| EP3374907B1 (en) * | 2015-11-10 | 2022-10-19 | Corteva Agriscience LLC | Methods and systems for predicting the risk of transgene silencing |
| US20190195864A1 (en) * | 2016-08-15 | 2019-06-27 | Enevolv, Inc. | Cell-free sensor systems |
| WO2019169150A1 (en) | 2018-03-02 | 2019-09-06 | Pioneer Hi-Bred International, Inc. | Plant health assay |
| US20210062203A1 (en) * | 2018-03-12 | 2021-03-04 | Pioneer Hi-Bred International, Inc. | Methods for plant transformation |
| BR112020026640A2 (pt) | 2018-06-28 | 2021-04-06 | Pioneer Hi-Bred International, Inc. | Métodos para selecionar plantas transformadas |
| AU2019369415A1 (en) | 2018-10-31 | 2021-03-25 | Pioneer Hi-Bred International, Inc. | Compositions and methods for Ochrobactrum-mediated plant transformation |
| CA3123457A1 (en) | 2019-03-11 | 2020-09-17 | Pioneer Hi-Bred International, Inc. | Methods for clonal plant production |
| WO2020198496A1 (en) | 2019-03-28 | 2020-10-01 | Pioneer Hi-Bred International, Inc. | Modified agrobacterium strains and use thereof for plant transformation |
| WO2025059184A1 (en) | 2023-09-12 | 2025-03-20 | Pioneer Hi-Bred International, Inc. | Methods and compositions for generating genome-edited paternal doubled haploids |
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| US564168A (en) * | 1896-07-14 | George armes tower | ||
| US4476227A (en) * | 1982-10-06 | 1984-10-09 | Smithkline Beckman Corporation | Cosmid cloning vectors |
| US5605011A (en) * | 1986-08-26 | 1997-02-25 | E. I. Du Pont De Nemours And Company | Nucleic acid fragment encoding herbicide resistant plant acetolactate synthase |
| DE4100594A1 (de) | 1991-01-08 | 1992-07-09 | Inst Genbiologische Forschung | Neue plasmide zur zeitlichen und oertlichen kontrollierten expression eines heterologen produktes in pflanzen |
| WO1994004672A1 (en) * | 1992-08-26 | 1994-03-03 | Dnx Corp. | Tetracycline repressor-mediated binary regulation system for control of gene expression in transgenic animals |
| US5888981A (en) | 1993-06-14 | 1999-03-30 | Basf Aktiengesellschaft | Methods for regulating gene expression |
| US5814618A (en) | 1993-06-14 | 1998-09-29 | Basf Aktiengesellschaft | Methods for regulating gene expression |
| JPH09500526A (ja) | 1993-06-14 | 1997-01-21 | ベーアーエスエフ アクツィエンゲゼルシャフト | テトラサイクリン反応性プロモーターによる真核細胞の遺伝子発現の厳密な制御 |
| US5859310A (en) | 1993-06-14 | 1999-01-12 | Basf Aktiengesellschaft | Mice transgenic for a tetracycline-controlled transcriptional activator |
| US5654168A (en) | 1994-07-01 | 1997-08-05 | Basf Aktiengesellschaft | Tetracycline-inducible transcriptional activator and tetracycline-regulated transcription units |
| US5789156A (en) | 1993-06-14 | 1998-08-04 | Basf Ag | Tetracycline-regulated transcriptional inhibitors |
| US5464758A (en) | 1993-06-14 | 1995-11-07 | Gossen; Manfred | Tight control of gene expression in eucaryotic cells by tetracycline-responsive promoters |
| US5866755A (en) | 1993-06-14 | 1999-02-02 | Basf Aktiengellschaft | Animals transgenic for a tetracycline-regulated transcriptional inhibitor |
| US5912411A (en) | 1993-06-14 | 1999-06-15 | University Of Heidelberg | Mice transgenic for a tetracycline-inducible transcriptional activator |
| US5589362A (en) | 1993-06-14 | 1996-12-31 | Basf Aktiengesellschaft | Tetracycline regulated transcriptional modulators with altered DNA binding specificities |
| US6004941A (en) | 1993-06-14 | 1999-12-21 | Basf Aktiengesellschaft | Methods for regulating gene expression |
| EG23907A (en) | 1994-08-01 | 2007-12-30 | Delta & Pine Land Co | Control of plant gene expression |
| US5723765A (en) | 1994-08-01 | 1998-03-03 | Delta And Pine Land Co. | Control of plant gene expression |
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| US6087166A (en) | 1997-07-03 | 2000-07-11 | Basf Aktiengesellschaft | Transcriptional activators with graded transactivation potential |
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| US20050034187A1 (en) | 2000-09-09 | 2005-02-10 | Andrei Golovko | Modified tet-inducible system for regulation of gene expression in plants |
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| GB0123401D0 (en) | 2001-09-28 | 2001-11-21 | Novartis Forschungsstiftung | Methods of inducing gene expression |
| US20030186281A1 (en) | 2001-12-21 | 2003-10-02 | Wolfgang Hillen | Modified tetracycline repressor protein compositions and methods of use |
| CN1385527A (zh) | 2002-02-08 | 2002-12-18 | 复旦大学 | 一种受化学除草剂诱导的启动子及其应用 |
| AU2003263199B2 (en) | 2002-08-28 | 2008-05-01 | Tet Systems Holding Gmbh & Co., Kg | Chromosomal loci for the stringent control of gene activities via transcription activation systems |
| US20040148649A1 (en) | 2002-10-03 | 2004-07-29 | Her Majesty The Queen In Right Of Canada As Represented By The Minister Of Agriculture And Foo | Repressor-mediated selection strategies |
| US20040133944A1 (en) | 2003-01-08 | 2004-07-08 | Delta And Pine Land Company | Seed oil suppression to enhance yield of commercially important macromolecules |
| GB2404382B (en) * | 2003-07-28 | 2008-01-30 | Oxitec Ltd | Pest control |
| US7491811B2 (en) | 2004-01-15 | 2009-02-17 | University Of Georgia Research Foundation, Inc. | Repressor-mediated tissue-specific gene expression in plants |
| US7674621B2 (en) * | 2004-05-21 | 2010-03-09 | The United States Of America As Represented By The Department Of Health And Human Services | Plasmids and phages for homologous recombination and methods of use |
| WO2005123923A2 (en) | 2004-06-17 | 2005-12-29 | Wolfgang Hillen | Inducer specific tetracycline repressor proteins and methods of use thereof |
| WO2006124502A2 (en) | 2005-05-12 | 2006-11-23 | Delta And Pine Land Company | An inducible genetic cascade for triggering protein expression in subsequent generations of plants |
| EP2431469A3 (en) | 2006-05-15 | 2012-05-30 | Paratek Pharmaceuticals, Inc. | Methods of regulating expression of genes or of gene products using substituted tetracycline compounds |
| US8080647B2 (en) * | 2006-11-22 | 2011-12-20 | Pioneer Hi Bred International Inc | Tetracycline repressor and uses thereof |
| EP2364322A1 (en) * | 2008-10-28 | 2011-09-14 | Pioneer Hi-Bred International Inc. | Sulfonylurea-responsive repressor proteins |
-
2009
- 2009-10-22 EP EP20090759826 patent/EP2364322A1/en not_active Withdrawn
- 2009-10-22 UA UAA201312853A patent/UA106458C2/uk unknown
- 2009-10-22 CN CN200980152630.8A patent/CN102264758B/zh not_active Expired - Fee Related
- 2009-10-22 MX MX2011003766A patent/MX2011003766A/es active IP Right Grant
- 2009-10-22 UA UAA201106478A patent/UA105017C2/uk unknown
- 2009-10-22 US US12/603,739 patent/US8257956B2/en active Active
- 2009-10-22 CA CA2740147A patent/CA2740147A1/en not_active Abandoned
- 2009-10-22 RU RU2011121542/10A patent/RU2532854C2/ru not_active IP Right Cessation
- 2009-10-22 US US13/120,895 patent/US8993315B2/en not_active Expired - Fee Related
- 2009-10-22 WO PCT/US2009/061661 patent/WO2010062518A1/en not_active Ceased
-
2011
- 2011-04-05 ZA ZA2011/02495A patent/ZA201102495B/en unknown
- 2011-05-13 US US13/107,212 patent/US8877503B2/en active Active
-
2012
- 2012-08-01 US US13/563,854 patent/US8580556B2/en active Active
-
2013
- 2013-10-03 US US14/045,087 patent/US20140033371A1/en not_active Abandoned
-
2015
- 2015-03-06 US US14/640,163 patent/US9206432B2/en active Active
- 2015-11-13 US US14/940,410 patent/US20160060304A1/en not_active Abandoned
Also Published As
| Publication number | Publication date |
|---|---|
| US20110294216A1 (en) | 2011-12-01 |
| CA2740147A1 (en) | 2010-06-03 |
| US8580556B2 (en) | 2013-11-12 |
| US8257956B2 (en) | 2012-09-04 |
| US20110212838A1 (en) | 2011-09-01 |
| US8993315B2 (en) | 2015-03-31 |
| RU2532854C2 (ru) | 2014-11-10 |
| CN102264758B (zh) | 2015-04-22 |
| ZA201102495B (en) | 2012-06-27 |
| US20100105141A1 (en) | 2010-04-29 |
| UA105017C2 (uk) | 2014-04-10 |
| EP2364322A1 (en) | 2011-09-14 |
| US8877503B2 (en) | 2014-11-04 |
| WO2010062518A1 (en) | 2010-06-03 |
| US20120295354A1 (en) | 2012-11-22 |
| RU2011121542A (ru) | 2012-12-10 |
| WO2010062518A4 (en) | 2010-08-05 |
| MX2011003766A (es) | 2011-04-27 |
| US9206432B2 (en) | 2015-12-08 |
| US20140033371A1 (en) | 2014-01-30 |
| CN102264758A (zh) | 2011-11-30 |
| US20160060304A1 (en) | 2016-03-03 |
| US20150184169A1 (en) | 2015-07-02 |
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