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UA105502C2 - Імплантований пристрій для введення октреатиду та спосіб його використання - Google Patents

Імплантований пристрій для введення октреатиду та спосіб його використання

Info

Publication number
UA105502C2
UA105502C2 UAA201105430A UAA201105430A UA105502C2 UA 105502 C2 UA105502 C2 UA 105502C2 UA A201105430 A UAA201105430 A UA A201105430A UA A201105430 A UAA201105430 A UA A201105430A UA 105502 C2 UA105502 C2 UA 105502C2
Authority
UA
Ukraine
Prior art keywords
octreotide
methods
delivery
implantable device
biostable
Prior art date
Application number
UAA201105430A
Other languages
English (en)
Russian (ru)
Inventor
Петр Кузма
Гарі Куандт
Original Assignee
Ендо Фармас'Ютікалз Солюшнз Інк.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ендо Фармас'Ютікалз Солюшнз Інк. filed Critical Ендо Фармас'Ютікалз Солюшнз Інк.
Publication of UA105502C2 publication Critical patent/UA105502C2/uk

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/04—Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
    • A61K38/08—Peptides having 5 to 11 amino acids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/12—Carboxylic acids; Salts or anhydrides thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/34—Macromolecular compounds obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyesters, polyamino acids, polysiloxanes, polyphosphazines, copolymers of polyalkylene glycol or poloxamers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
    • A61K47/69—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the conjugate being characterised by physical or galenical forms, e.g. emulsion, particle, inclusion complex, stent or kit
    • A61K47/6957—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the conjugate being characterised by physical or galenical forms, e.g. emulsion, particle, inclusion complex, stent or kit the form being a device or a kit, e.g. stents or microdevices
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
    • A61K9/0024—Solid, semi-solid or solidifying implants, which are implanted or injected in body tissue
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0087—Galenical forms not covered by A61K9/02 - A61K9/7023
    • A61K9/0092—Hollow drug-filled fibres, tubes of the core-shell type, coated fibres, coated rods, microtubules or nanotubes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/12—Antidiarrhoeals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/18—Drugs for disorders of the alimentary tract or the digestive system for pancreatic disorders, e.g. pancreatic enzymes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00—Drugs for disorders of the endocrine system
    • A61P5/10—Drugs for disorders of the endocrine system of the posterior pituitary hormones, e.g. oxytocin, ADH
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Epidemiology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Dermatology (AREA)
  • Immunology (AREA)
  • Biomedical Technology (AREA)
  • Neurosurgery (AREA)
  • Nanotechnology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Diabetes (AREA)
  • Inorganic Chemistry (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Endocrinology (AREA)
  • Cardiology (AREA)
  • Obesity (AREA)
  • Hematology (AREA)
  • Emergency Medicine (AREA)
  • Medicinal Preparation (AREA)
  • Materials For Medical Uses (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

Винахід належить до застосування полімеру на основі поліуретану, який містить полільний фрагмент -[O-(CH)]-O-, як пристрою для доставки твердого лікарського засобу октреотиду з постійною швидкістю протягом тривалого періоду часу, і до способів його отримання. Пристрій має високу біосумісність і біостійкість і може застосовуватись як імплантат для пацієнтів (людей і тварин) для доставки октреотиду до тканин або органів.
UAA201105430A 2008-09-30 2009-09-29 Імплантований пристрій для введення октреатиду та спосіб його використання UA105502C2 (uk)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US10155208P 2008-09-30 2008-09-30
PCT/US2009/058801 WO2010039717A1 (en) 2008-09-30 2009-09-29 Implantable device for the delivery of octreotide and methods of use thereof

Publications (1)

Publication Number Publication Date
UA105502C2 true UA105502C2 (uk) 2014-05-26

Family

ID=41557438

Family Applications (1)

Application Number Title Priority Date Filing Date
UAA201105430A UA105502C2 (uk) 2008-09-30 2009-09-29 Імплантований пристрій для введення октреатиду та спосіб його використання

Country Status (14)

Country Link
US (4) US20110244015A1 (uk)
EP (1) EP2344122A1 (uk)
JP (1) JP2012504144A (uk)
KR (1) KR20110066934A (uk)
CN (1) CN102202645A (uk)
AU (1) AU2009298711B2 (uk)
BR (1) BRPI0920752A2 (uk)
CA (1) CA2739180C (uk)
IL (1) IL211953A (uk)
MX (1) MX2011003300A (uk)
RU (1) RU2549473C2 (uk)
UA (1) UA105502C2 (uk)
WO (1) WO2010039717A1 (uk)
ZA (1) ZA201102949B (uk)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7858110B2 (en) 2003-08-11 2010-12-28 Endo Pharmaceuticals Solutions, Inc. Long term drug delivery devices with polyurethane based polymers and their manufacture
CA2437639C (en) 2003-08-11 2016-07-05 Valera Pharmaceuticals, Inc. Long term drug delivery devices with polyurethane based polymers and their manufacture
EP2344122A1 (en) * 2008-09-30 2011-07-20 Endo Pharmaceuticals Solutions Inc. Implantable device for the delivery of octreotide and methods of use thereof
WO2010039722A1 (en) 2008-09-30 2010-04-08 Endo Pharmaceuticals Solutions Inc. Implantable device for the delivery of risperidone and methods of use thereof
CA2853249A1 (en) 2011-10-24 2013-05-02 Endo Pharmaceuticals Solutions Inc. Implantable tizanidine compositions and methods of treatment thereof
HUE035214T2 (hu) * 2011-10-24 2018-05-02 Braeburn Pharmaceuticals Inc Beültethetõ hatóanyag adagoló készítmények és az ezekkel végzett kezelési eljárás
JP2014530913A (ja) * 2011-10-24 2014-11-20 エンドゥ ファーマシューティカルズ ソリューションズ インコーポレイティド 移植可能ラサギリン組成物及びその治療方法
SG10201708522SA (en) 2013-03-15 2017-12-28 Taris Biomedical Llc Drug delivery devices with drug-permeable component and methods
BR112016025045A2 (pt) * 2014-05-30 2017-08-15 Textile Based Delivery Inc sistema de distribuição de fármaco e método de distribuição de um composto biologicamente ativo
KR102658706B1 (ko) 2015-04-23 2024-04-17 타리스 바이오메디컬 엘엘씨 약물-투과성 성분을 구비한 약물 전달 장치 및 방법
US11820890B2 (en) 2021-04-01 2023-11-21 Stratasys Inc Pulverulent thermoplastic polymer blends

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5035891A (en) * 1987-10-05 1991-07-30 Syntex (U.S.A.) Inc. Controlled release subcutaneous implant
CA2367100A1 (en) * 1999-04-01 2000-10-12 Alza Corporation Transdermal drug delivery devices comprising a polyurethane drug reservoir
DE60327626D1 (de) * 2002-05-23 2009-06-25 Active Implants Corp Gelenk- und zahnimplantate
CA2437639C (en) * 2003-08-11 2016-07-05 Valera Pharmaceuticals, Inc. Long term drug delivery devices with polyurethane based polymers and their manufacture
EP1781264B1 (en) * 2004-08-04 2013-07-24 Evonik Corporation Methods for manufacturing delivery devices and devices thereof
NZ561400A (en) * 2005-03-11 2010-02-26 Endo Pharmaceuticals Solutions Controlled release formulations of octreotide
US7960335B2 (en) * 2008-06-25 2011-06-14 Endo Pharmaceuticals Solutions Inc. Octreotide implant having a release agent and uses thereof
EP2344122A1 (en) * 2008-09-30 2011-07-20 Endo Pharmaceuticals Solutions Inc. Implantable device for the delivery of octreotide and methods of use thereof

Also Published As

Publication number Publication date
EP2344122A1 (en) 2011-07-20
AU2009298711A1 (en) 2010-04-08
IL211953A0 (en) 2011-06-30
ZA201102949B (en) 2015-12-23
IL211953A (en) 2015-11-30
BRPI0920752A2 (pt) 2015-12-22
KR20110066934A (ko) 2011-06-17
US20150283201A1 (en) 2015-10-08
US20210161994A1 (en) 2021-06-03
AU2009298711B2 (en) 2015-10-29
JP2012504144A (ja) 2012-02-16
WO2010039717A1 (en) 2010-04-08
CA2739180A1 (en) 2010-04-08
US20190365847A1 (en) 2019-12-05
RU2011117327A (ru) 2012-11-10
RU2549473C2 (ru) 2015-04-27
CA2739180C (en) 2017-12-19
MX2011003300A (es) 2011-06-09
US20110244015A1 (en) 2011-10-06
CN102202645A (zh) 2011-09-28

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