TWI843542B - Left atrial appendage occluder determining method, left atrial parameter acquiring method and system thereof - Google Patents

Abstract

A left atrial parameter acquiring method is proposed. The left atrial parameter acquiring method includes an imaging acquiring step, a heart model establishing step, a center route calculating step, a cross section setting step and a left atrial parameter calculating step. The imaging acquiring step is performed to acquire a chest computed tomography (CT) image sequence. The heart model establishing step is performed to combine the chest CT scanning images into a three-dimensional heart model. The center route calculating step is performed to acquire a first coordinate corresponding to a fossa ovale and a second coordinate corresponding to a left atrial, and calculate a center route between the fossa ovale and the left atrial. The cross section setting step is performed to set a cross section. The cross section is corresponding to an opening of the left atrial. The left atrial parameter calculating step is performed to calculate a left atrial parameter. Thus, the left atrial parameter acquiring method of the present disclosure can calculate the left atrial parameter according to the three-dimensional heart model.

Description

Left atrial appendage occluder determination method, left atrial appendage parameter acquisition method and system

The present invention relates to an occluder determination method, a parameter acquisition method and a system thereof, and in particular to a left atrial appendage occluder determination method, a left atrial appendage parameter acquisition method and a system thereof.

In current LAA occlusion surgery, transesophageal echocardiography (TEE) is performed before surgery. An ultrasound probe similar to an endoscope is placed in the esophagus and stomach to measure the size and depth of the LAA opening through two-dimensional cardiac images at different angles of 0, 45, 90, and 135 degrees. However, if the LAA opening size measured by TEE is inaccurate and the selected occluder cannot be fixed in the LAA, it may cause postoperative complications of LAA occlusion surgery, such as occluder dislocation.

In view of this, developing a method for determining the left atrial appendage occluder, a method for obtaining left atrial appendage parameters and a system thereof, which can establish a three-dimensional heart model through chest sectional scan images and accurately calculate the size and depth of the left atrial appendage opening, has become a goal worthy of research and development for relevant industries.

Therefore, the purpose of the present invention is to provide a method for determining a left atrial appendage occluder, a method for obtaining left atrial appendage parameters and a system thereof, which establish a three-dimensional heart model based on chest tomographic scan images, and then calculate the left atrial appendage parameters and determine the size of the left atrial appendage occluder.

According to one embodiment of the method of the present invention, a method for obtaining left atrial appendage parameters is provided, comprising an image obtaining step, a heart model building step, a central path calculation step, a section setting step and a left atrial appendage parameter calculation step. The image obtaining step is to drive a processor to obtain a chest cross-sectional image sequence from a database. The chest cross-sectional image sequence includes a plurality of chest cross-sectional scan images. The heart model building step is to drive the processor to combine these chest cross-sectional scan images to generate a three-dimensional heart model. The central path calculation step is to drive the processor to obtain a first coordinate corresponding to an oval fossa and a second coordinate corresponding to a left atrial appendage from the three-dimensional heart model, and calculate a central path between the first coordinate and the second coordinate. The section setting step is to drive the processor to set a section according to the second coordinate and the central path. The section corresponds to a left atrial appendage opening, the section and the central path intersect at an intersection, and the direction of a section line of the central path along the intersection is parallel to a normal direction of the section. The left atrial appendage parameter calculation step is to drive the processor to calculate a left atrial appendage parameter according to the left atrial appendage opening in the section. The left atrial appendage parameter includes an opening area, an opening circumference, a longest diameter, a shortest diameter and a depth.

Thus, the left atrial appendage parameter acquisition method of the present invention establishes a three-dimensional heart model based on the patient's chest cross-sectional scan image, thereby accurately acquiring the patient's left atrial appendage parameters.

Other embodiments of the aforementioned implementation are as follows: The aforementioned heart model building step may include a region segmentation step and a model generation step. The region segmentation step is to drive the processor to convert these chest tomographic scan images into a plurality of heart regional images according to a region growth algorithm. The model generation step is to drive the processor to convert these heart regional images into a three-dimensional heart model according to a marching block algorithm.

Other embodiments of the aforementioned implementation are as follows: The aforementioned center path calculation step may include an inscribed sphere radius calculation step and an operation step. The inscribed sphere radius calculation step is to drive the processor to calculate the multiple inscribed sphere radii of the three-dimensional heart model. The operation step is to drive the processor to calculate the center path according to a center path calculation rule. The center path calculation rule conforms to the following formula: .

Indicates the center path; Indicates the first coordinate; Indicates the second coordinate; Indicates the corresponding point The radius of one of the spheres inscribed in ; , and Represent points A coordinate value on an X-axis, a Y-axis, and a Z-axis.

Other embodiments of the aforementioned embodiment are as follows: The aforementioned left atrial appendage parameter calculation step may include a contour marking step and a parameter calculation step. The contour marking step is to drive the processor to mark a left atrial appendage contour line from the three-dimensional heart model according to the section. The parameter calculation step is to drive the processor to calculate the left atrial appendage parameters according to the left atrial appendage contour line.

According to one implementation method of the structural aspect of the present invention, a left atrial appendage parameter acquisition system is provided, comprising a database and a processor. The database is used to access a chest tomographic image sequence. The chest tomographic image sequence comprises a plurality of chest tomographic scan images. The processor signal is connected to the database. The processor receives the chest tomographic image sequence and is configured to implement a left atrial appendage parameter acquisition method. The left atrial appendage parameter acquisition method comprises a heart model establishment step, a central path calculation step, a section setting step and a left atrial appendage parameter calculation step. The heart model establishment step combines these chest tomographic scan images to generate a three-dimensional heart model. The central path calculation step is to obtain a first coordinate corresponding to an oval fossa and a second coordinate corresponding to a left atrial appendage from the three-dimensional heart model, and calculate a central path between the first coordinate and the second coordinate. The section setting step is to set a section according to the second coordinate and the central path. The section corresponds to a left atrial appendage opening, the section and the central path intersect at an intersection, and the direction of a section line of the central path along the intersection is parallel to a normal direction of the section. The left atrial appendage parameter calculation step is to calculate a left atrial appendage parameter according to the left atrial appendage opening in the section. The left atrial appendage parameter includes an opening area, an opening perimeter, a longest diameter, a shortest diameter and a depth.

Thus, the left atrial appendage parameter acquisition system of the present invention establishes a three-dimensional heart model based on the patient's chest sectional scan image, and then accurately acquires the patient's left atrial appendage parameters.

Other embodiments of the aforementioned implementation are as follows: The aforementioned heart model building step may include a region segmentation step and a model generation step. The region segmentation step converts these chest tomographic scan images into a plurality of heart regional images according to a region growth algorithm. The model generation step converts these heart regional images into a three-dimensional heart model according to a marching block algorithm.

Other embodiments of the aforementioned implementation are as follows: The aforementioned center path calculation step may include an inscribed sphere radius calculation step and an operation step. The inscribed sphere radius calculation step is to calculate a plurality of inscribed sphere radii of the three-dimensional heart model. The operation step is to calculate the center path according to a center path calculation rule. The center path calculation rule conforms to the following formula: .

Indicates the center path; Indicates the first coordinate; Indicates the second coordinate; Indicates the corresponding point The radius of one of the spheres inscribed in ; , and Respectively indicate points A coordinate value on an X-axis, a Y-axis, and a Z-axis.

Other embodiments of the aforementioned embodiment are as follows: The aforementioned left atrial appendage parameter calculation step may include a contour marking step and a parameter calculation step. The contour marking step is to mark a left atrial appendage contour line from the three-dimensional heart model according to the section. The parameter calculation step is to calculate the left atrial appendage parameters according to the left atrial appendage contour line.

According to another embodiment of the method aspect of the present invention, a method for determining a left atrial appendage occluder is provided, comprising an image acquisition step, a heart model establishment step, a central path calculation step, a section setting step, a left atrial appendage parameter calculation step, and an occluder determination step. The image acquisition step is to drive a processor to obtain a chest cross-sectional image sequence from a database. The chest cross-sectional image sequence includes a plurality of chest cross-sectional scan images. The heart model establishment step is to drive the processor to combine these chest cross-sectional scan images to generate a three-dimensional heart model. The central path calculation step is to drive the processor to obtain a first coordinate corresponding to an oval fossa and a second coordinate corresponding to a left atrial appendage from the three-dimensional heart model, and calculate a central path between the first coordinate and the second coordinate. The section setting step is to drive the processor to set a section according to the second coordinate and the central path. The section corresponds to a left atrial appendage opening, and the section and the central path intersect at an intersection. The left atrial appendage parameter calculation step is to drive the processor to calculate a left atrial appendage parameter according to the left atrial appendage opening in the section. The occluder determination step is to drive the processor to determine the size of a left atrial appendage occluder according to the left atrial appendage parameters.

Thus, the left atrial appendage occluder determination method of the present invention can measure left atrial appendage related parameters before surgery to assist doctors in determining the size of the occluder.

Other embodiments of the aforementioned implementation are as follows: The aforementioned heart model building step may include a region segmentation step and a model generation step. The region segmentation step is to drive the processor to convert these chest tomographic scan images into a plurality of heart regional images according to a region growth algorithm. The model generation step is to drive the processor to convert these heart regional images into a three-dimensional heart model according to a marching block algorithm.

Other embodiments of the aforementioned implementation are as follows: The aforementioned center path calculation step may include an inscribed sphere radius calculation step and an operation step. The inscribed sphere radius calculation step is to drive the processor to calculate the multiple inscribed sphere radii of the three-dimensional heart model. The operation step is to drive the processor to calculate the center path according to a center path calculation rule. The center path calculation rule conforms to the following formula: .

Indicates the center path; Indicates the first coordinate; Indicates the second coordinate; Indicates corresponding point The radius of one of the spheres inscribed in ; , and Represent points A coordinate value on an X-axis, a Y-axis, and a Z-axis.

Other embodiments of the aforementioned embodiment are as follows: The aforementioned left atrial appendage parameter calculation step may include a contour marking step and a parameter calculation step. The contour marking step is to drive the processor to mark a left atrial appendage contour line from the three-dimensional heart model according to the section. The parameter calculation step is to drive the processor to calculate the left atrial appendage parameters according to the left atrial appendage contour line.

The following will describe several embodiments of the present invention with reference to the drawings. For the sake of clarity, many practical details will be described together in the following description. However, it should be understood that these practical details should not be used to limit the present invention. That is to say, in some embodiments of the present invention, these practical details are not necessary. In addition, in order to simplify the drawings, some commonly known structures and components will be depicted in the drawings in a simple schematic manner; and repeated components may be represented by the same number.

In addition, in this article, when a certain component (or unit or module, etc.) is "connected" to another component, it may refer to that the component is directly connected to the other component, or it may refer to that the component is indirectly connected to the other component, that is, there are other components between the component and the other component. When it is clearly stated that a certain component is "directly connected" to another component, it means that there are no other components between the component and the other component. The terms first, second, third, etc. are only used to describe different components, and there is no restriction on the components themselves. Therefore, the first component can also be renamed as the second component. Moreover, the combination of components/units/circuits in this article is not a generally known, conventional or familiar combination in this field. Whether the components/units/circuits themselves are known cannot be used to determine whether their combination relationship is easy to be completed by ordinary knowledge in the technical field.

Please refer to Figures 1 to 4, Figure 1 is a flow chart of the left atrial appendage parameter acquisition method S10 of the first embodiment of the present invention; Figure 2 is a schematic diagram of an oval fossa 12 and a left atrial appendage 14 of the heart 10; Figure 3 is a schematic diagram of a central path RC according to the central path calculation step S03 of the left atrial appendage parameter acquisition method S10 of Figure 1; and Figure 4 is a schematic diagram of a section C1 of the section setting step S04 of the left atrial appendage parameter acquisition method S10 of Figure 1. The left atrial appendage parameter acquisition method S10 includes an image acquisition step S01, a heart model establishment step S02, a central path calculation step S03, a section setting step S04 and a left atrial appendage parameter calculation step S05. The image acquisition step S01 is to drive a processor to acquire a chest tomographic image sequence from a database. The chest tomographic image sequence includes a plurality of chest tomographic scan images. Specifically, the chest tomographic image sequence includes a plurality of chest tomographic scan images arranged in sequence, and the slice thickness of these chest tomographic scan images can be 0.625 mm, but the present invention is not limited thereto.

Please refer to Figures 2 and 3. The heart model building step S02 drives the processor to combine these chest sectional scan images to generate a three-dimensional heart model. The center path calculation step S03 drives the processor to obtain a first coordinate P1 corresponding to an oval fossa 12 and a second coordinate P2 corresponding to a left atrial appendage 14 from the three-dimensional heart model, and calculates the center path RC between the first coordinate P1 and the second coordinate P2. In other words, the heart model building step S02 combines and connects these two-dimensional chest sectional scan images to build a three-dimensional heart model. In the first embodiment, the three-dimensional heart model includes the left atrium 13, the right atrium 11, the left ventricle, the right ventricle, the left atrial appendage 14, the right atrial appendage (not shown), the superior great vein, the inferior great vein, the aorta, the pulmonary vein and the pulmonary artery in the heart 10, but the present invention is not limited thereto. Specifically, in the occlusion operation of the left atrial appendage 14, the doctor punctures the cardiac catheter T from the right atrium 11 into the left atrium 13, and then places the occluder 20 in the left atrial appendage opening 14a of the left atrial appendage 14, and the oval fossa 12 of the right atrium 11 is an ideal puncture site for the cardiac catheter T operation from the right atrium 11 into the left atrium 13. Therefore, the central path RC calculated in the central path calculation step S03 can be a moving path of the simulated cardiac catheter T moving from the oval fossa 12 to the left atrial appendage 14 during the occlusion surgery of the left atrial appendage 14.

Please refer to Figures 2 to 4. The section setting step S04 drives the processor to set the section C1 according to the second coordinate P2 and the center path RC. The section C1 corresponds to a left atrial appendage opening 14a. The section C1 and the center path RC intersect at an intersection P3. The tangent direction D2 of the center path RC along the intersection P3 is parallel to a normal direction D1 of the section C1. In other words, after simulating the center path RC of the cardiac catheter T, the section setting step S04 is used to find the position on the center path RC corresponding to the left atrial appendage opening 14a (i.e., the intersection P3), and set the section C1 to calculate the left atrial appendage parameter PR. In addition, the section C1 is perpendicular to the center path RC at the intersection P3. The center path RC shown in FIG. 3 is only used to illustrate the relative position relationship among the first coordinate P1, the second coordinate P2, the intersection point P3, the section C1, the normal direction D1 and the tangential direction D2, and does not present the moving path of the cardiac catheter T in FIG. 2.

The left atrial appendage parameter calculation step S05 drives the processor to calculate a left atrial appendage parameter PR according to the left atrial appendage opening 14a in the section C1. The left atrial appendage parameter PR includes an opening area, an opening perimeter, a longest diameter, a shortest diameter and a depth. Specifically, the left atrial appendage parameter calculation step S05 is used to check the position of the section C1 in the three-dimensional heart model, and measure and calculate the left atrial appendage parameter PR corresponding to the section C1. In FIG. 4 , the area of the opening of the left atrial appendage 14 is 189.91 square millimeters (mm ² ); the depth of the left atrial appendage 14 is 12.40 millimeters (mm); the circumference of the opening of the left atrial appendage 14 is 65.65 millimeters; the longest diameter of the left atrial appendage 14 is 28.54 millimeters; the shortest diameter of the left atrial appendage 14 is 13.04 millimeters; the recommended implant size of the occluder 20 is 22.57-24.03 millimeters, and the implant size corresponds to the circumference of the opening, the longest diameter, and the shortest diameter of the left atrial appendage 14, but the present invention is not limited thereto.

Thus, the left atrial appendage parameter acquisition method S10 of the present invention establishes a three-dimensional heart model HM based on the patient's chest sectional scan image, which assists the doctor in understanding the structure and shape of the patient's left atrial appendage 14. Therefore, the left atrial appendage parameter PR can be obtained without performing invasive transesophageal echocardiography (TEE) on the patient. The details of the heart model establishment step S02, the central path calculation step S03 and the left atrial appendage parameter calculation step S05 will be described below through a more detailed embodiment.

Please refer to FIG. 1, FIG. 5 to FIG. 7, FIG. 5 is a flow chart of the left atrial appendage parameter acquisition method S10a of the second embodiment of the present invention; FIG. 6 is a schematic diagram of the central path calculation step S03 of the left atrial appendage parameter acquisition method S10a according to FIG. 5; and FIG. 7 is a block diagram of the left atrial appendage parameter acquisition system 100 of the third embodiment of the present invention. In the second embodiment, the left atrial appendage parameter acquisition method S10a includes an image acquisition step S01, a heart model establishment step S02, a central path calculation step S03, a section setting step S04, and a left atrial appendage parameter calculation step S05. The image acquisition step S01 and the section setting step S04 of the left atrial appendage parameter acquisition method S10a are respectively the same as the image acquisition step S01 and the section setting step S04 of the left atrial appendage parameter acquisition method S10 of the first embodiment, and will not be repeated. In particular, the heart model establishment step S02 may include a region segmentation step S021 and a model generation step S022. The center path calculation step S03 may include an inscribed sphere radius calculation step S031 and a calculation step S032. The left atrial appendage parameter calculation step S05 may include a contour marking step S051 and a parameter calculation step S052. In the third embodiment, the left atrial appendage parameter acquisition system 100 includes a database 110 and a processor 120. The database 110 is used to access a chest tomographic image sequence CT_set. The chest tomographic image sequence CT_set includes a plurality of chest tomographic scan images CT. The processor 120 is signal-connected to the database 110. The processor 120 receives the chest tomographic image sequence CT_set and is configured to implement the left atrial appendage parameter acquisition method S10 or the left atrial appendage parameter acquisition method S10a. Specifically, the database 110 may include a random access memory (RAM) or other types of dynamic storage devices that can store information and instructions for execution by the processor 120. The processor 120 may include any type of processor or microprocessor, but the present invention is not limited thereto.

The region segmentation step S021 drives the processor 120 to convert these chest cross-sectional scan images CT into a plurality of heart regional images according to a region growing algorithm ME1. The model generation step S022 drives the processor 120 to convert these heart regional images into a three-dimensional heart model HM according to a marching cubes algorithm ME2. Specifically, the region growing algorithm ME1 is used to extract the regional image of the heart 10 in each chest cross-sectional scan image CT, and exclude unnecessary information outside the heart region in the chest cross-sectional scan image CT. The marching block algorithm ME2 is used to connect all the heart region images in the chest cross-sectional image sequence CT_set to form a three-dimensional heart model HM.

The inscribed sphere radius calculation step S031 is to drive the processor 120 to calculate the multiple inscribed sphere radii of the three-dimensional heart model HM. The calculation step S032 is to drive the processor 120 to calculate the center path RC according to a center path calculation rule ME3. The center path calculation rule ME3 meets the following formula (1): (1).

represents the center path RC; Indicates the first coordinate P1; represents the second coordinate P2; Indicates the corresponding point The radius of the inscribed sphere of , and Represent points A coordinate value on an X-axis, a Y-axis, and a Z-axis.

Specifically, since the three-dimensional heart model HM is an irregular shape, it may have different inscribed sphere radii at different positions. The inscribed sphere radius calculation step S031 is used to calculate the inscribed sphere radius of each point. The calculation step S032 uses the inverse of these inscribed sphere radii to make each point on the calculated center path RC close to the center of the inscribed sphere of the three-dimensional heart model HM. The larger the value, the farther the point p is from the edge of the three-dimensional heart model HM; The smaller the value, the closer the point p is to the edge of the three-dimensional heart model HM.

The contour marking step S051 is to drive the processor 120 to mark a left atrial appendage contour line from the three-dimensional heart model HM according to the section C1. The parameter calculation step S052 is to drive the processor 120 to calculate the left atrial appendage parameter PR according to the left atrial appendage contour line. Thus, the left atrial appendage parameter acquisition system 100 of the present invention in conjunction with the left atrial appendage parameter acquisition method S10a can simulate the central path RC of the central catheter T of the left atrial appendage 14 occlusion surgery, and assist the doctor in planning the implantation angle and position of the occluder 20.

Please refer to FIG. 1 and FIG. 8, FIG. 8 is a flow chart of the left atrial appendage occluder determination method S20 of the fourth embodiment of the present invention. The left atrial appendage occluder determination method S20 includes an image acquisition step S11, a heart model establishment step S12, a center path calculation step S13, a section setting step S14, a left atrial appendage parameter calculation step S15 and an occluder determination step S16. Specifically, the image acquisition step S11, the heart model establishment step S12, the center path calculation step S13, the section setting step S14, and the left atrial appendage parameter calculation step S15 of the left atrial appendage occluder decision method S20 can be respectively the same as the image acquisition step S01, the heart model establishment step S02, the center path calculation step S03, the section setting step S04, and the left atrial appendage parameter calculation step S05 in the left atrial appendage parameter acquisition method S10 or the left atrial appendage parameter acquisition method S10a, and will not be repeated here. Particularly, the LAA occluder determination method S20 further comprises an occluder determination step S16, wherein the occluder determination step S16 drives the processor to determine the size of an occluder 20 of the LAA 14 according to the LAA parameter PR.

Specifically, the occluder determination step S16 is used to calculate the recommended diameter range and the appropriate size of the occluder 20 according to the opening circumference of the left atrial appendage 14. Thus, the left atrial appendage occluder determination method S20 of the present invention can measure the left atrial appendage parameter PR before surgery, and assist the doctor in determining the size of the occluder 20, so as to avoid the problem of the occluder 20 falling off or the left atrial appendage 14 rupture caused by the size of the occluder 20 not matching the left atrial appendage 14 of the patient.

From the above implementation, it can be seen that the present invention has the following advantages. First, the left atrial appendage parameter acquisition method of the present invention establishes a three-dimensional heart model based on the patient's chest sectional scan image, which assists doctors in understanding the structure and shape of the patient's left atrial appendage. Therefore, the left atrial appendage parameters can be obtained without performing invasive transesophageal cardiac ultrasound on the patient. Second, the left atrial appendage parameter acquisition system of the present invention can simulate the central path of the central catheter of the left atrial appendage occlusion surgery in conjunction with the left atrial appendage parameter acquisition method, and assist doctors in planning the implantation angle and position of the occluder. Third, the left atrial appendage occluder determination method of the present invention can measure the left atrial appendage parameters before the operation, and assist doctors in determining the size of the occluder, thereby avoiding the problem of occluder detachment or left atrial appendage rupture caused by the incompatibility of the occluder size with the patient's left atrial appendage.

Although the present invention has been disclosed in the above embodiments, it is not intended to limit the present invention. Anyone skilled in the art can make various changes and modifications without departing from the spirit and scope of the present invention. Therefore, the protection scope of the present invention shall be subject to the scope defined in the attached patent application.

10: Heart

11: Right atrium

12: Oval fossa

13: Left atrium

14: Left atrial appendage

14a: Left atrial appendage opening

20: Occluder

100: Left atrial appendage parameter acquisition system

110: Database

120:Processor

S01, S11: Image acquisition step

S02, S12: Heart model establishment steps

S021: Region segmentation step

S022: Model generation step

S03, S13: Center path calculation step

S031: Inscribed sphere radius calculation step

S032: Calculation steps

S04, S14: Slice setting step

S05, S15: Left atrial appendage parameter calculation step

S051: Contour marking step

S052: Parameter calculation step

S10, S10a: Method for obtaining left atrial appendage parameters

S20: Left Atrial Appendage Occluder Decision Method

S16: Occluder decision step

CT: Chest cross-sectional scan

CT_set: chest cross-sectional image sequence

C1: Section

D1: Normal direction

D2: Tangent direction

HM: 3D heart model

ME1: Region Growth Algorithm

ME2: Marching Blocks Algorithm

ME3: Center path calculation rules

p:point

PR: Left atrial appendage parameters

P1: first coordinate

P2: Second coordinate

P3: Intersection point

RC: Center Path

T: Cardiac catheter

Figure 1 is a flow chart of the left atrial appendage parameter acquisition method of the first embodiment of the present invention; Figure 2 is a schematic diagram of the oval fossa and left atrial appendage of the heart; Figure 3 is a schematic diagram of the center path of the center path calculation step of the left atrial appendage parameter acquisition method according to Figure 1; Figure 4 is a schematic diagram of the section setting step of the left atrial appendage parameter acquisition method according to Figure 1; Figure 5 is a flow chart of the left atrial appendage parameter acquisition method of the second embodiment of the present invention; Figure 6 is a schematic diagram of the center path calculation step of the left atrial appendage parameter acquisition method according to Figure 5; Figure 7 is a block diagram of the left atrial appendage parameter acquisition system of the third embodiment of the present invention; and Figure 8 is a flow chart showing the left atrial appendage occluder determination method of the fourth embodiment of the present invention.

S01: Image acquisition step

S02: Steps to build a heart model

S03: Center path calculation step

S04: Section setting steps

S05: Left atrial appendage parameter calculation step

S10: Method for obtaining left atrial appendage parameters

Claims (12)

A method for obtaining left atrial appendage parameters comprises: an image acquisition step, which drives a processor to obtain a chest cross-sectional image sequence from a database, wherein the chest cross-sectional image sequence comprises a plurality of chest cross-sectional scan images; a heart model establishment step, which drives the processor to combine the chest cross-sectional scan images to generate a three-dimensional heart model; a central path calculation step, which drives the processor to obtain a first coordinate corresponding to an oval fossa and a second coordinate corresponding to a left atrial appendage from the three-dimensional heart model, and calculate a central path between the first coordinate and the second coordinate; A section setting step is to drive the processor to set a section according to the second coordinate and the central path, wherein the section corresponds to a left atrial appendage opening, the section intersects the central path at an intersection, and the direction of a tangent line of the central path along the intersection is parallel to a normal direction of the section; and a left atrial appendage parameter calculation step is to drive the processor to calculate a left atrial appendage parameter according to the left atrial appendage opening in the section; wherein the left atrial appendage parameter includes an opening area, an opening perimeter, a longest diameter, a shortest diameter and a depth. The left atrial appendage parameter acquisition method as described in claim 1, wherein the heart model establishment step includes: a region segmentation step, which drives the processor to convert the chest tomographic scan images into a plurality of heart regional images according to a region growth algorithm; and a model generation step, which drives the processor to convert the heart regional images into the three-dimensional heart model according to a marching block algorithm. The method for obtaining left atrial appendage parameters as described in claim 1, wherein the central path calculation step comprises: an inscribed sphere radius calculation step, which drives the processor to calculate the multiple inscribed sphere radii of the three-dimensional heart model; and a calculation step, which drives the processor to calculate the central path according to a central path calculation rule, wherein the central path calculation rule conforms to the following formula: ; in represents the center path; represents the first coordinate; represents the second coordinate; Indicates the corresponding point one of the radii of the inscribed sphere; , and Represent points A coordinate value on an X-axis, a Y-axis, and a Z-axis. The method for obtaining left atrial appendage parameters as described in claim 1, wherein the left atrial appendage parameter calculation step comprises: a contour marking step, which drives the processor to mark a left atrial appendage contour line from the three-dimensional heart model according to the section; and a parameter calculation step, which drives the processor to calculate the left atrial appendage parameters according to the left atrial appendage contour line. A left atrial appendage parameter acquisition system comprises: A database for accessing a chest sectional image sequence, wherein the chest sectional image sequence comprises a plurality of chest sectional scan images; and A processor, signal-connected to the database, the processor receives the chest sectional image sequence, and is configured to implement a left atrial appendage parameter acquisition method, the left atrial appendage parameter acquisition method comprising: A heart model establishment step, which combines the chest sectional scan images to generate a three-dimensional heart model; A central path calculation step, which obtains a first coordinate corresponding to an oval fossa and a second coordinate corresponding to a left atrial appendage from the three-dimensional heart model, and calculates a central path between the first coordinate and the second coordinate; A section setting step is to set a section according to the second coordinate and the central path, wherein the section corresponds to a left atrial appendage opening, the section intersects the central path at an intersection, and the direction of a tangent line of the central path along the intersection is parallel to a normal direction of the section; and a left atrial appendage parameter calculation step is to calculate a left atrial appendage parameter according to the left atrial appendage opening in the section; wherein the left atrial appendage parameter includes an opening area, an opening perimeter, a longest diameter, a shortest diameter and a depth. The left atrial appendage parameter acquisition system as described in claim 5, wherein the heart model establishment step includes: a region segmentation step, which converts the chest tomographic scan images into a plurality of heart regional images according to a region growth algorithm; and a model generation step, which converts the heart regional images into the three-dimensional heart model according to a marching block algorithm. The left atrial appendage parameter acquisition system as described in claim 5, wherein the central path calculation step includes: an inscribed sphere radius calculation step, which calculates the multiple inscribed sphere radii of the three-dimensional heart model; and a calculation step, which calculates the central path according to a central path calculation rule, wherein the central path calculation rule conforms to the following formula: ; in represents the center path; represents the first coordinate; represents the second coordinate; Indicates the corresponding point one of the radii of the inscribed sphere; , and Represent points A coordinate value on an X-axis, a Y-axis, and a Z-axis. The left atrial appendage parameter acquisition system as described in claim 5, wherein the left atrial appendage parameter calculation step includes: a contour marking step, which is to mark a left atrial appendage contour line from the three-dimensional heart model according to the section; and a parameter calculation step, which is to calculate the left atrial appendage parameter according to the left atrial appendage contour line. A method for determining a left atrial appendage occluder comprises: an image acquisition step, which drives a processor to acquire a chest cross-sectional image sequence from a database, wherein the chest cross-sectional image sequence comprises a plurality of chest cross-sectional scan images; a heart model establishment step, which drives the processor to combine the chest cross-sectional scan images to generate a three-dimensional heart model; a central path calculation step, which drives the processor to acquire a first coordinate corresponding to an oval fossa and a second coordinate corresponding to a left atrial appendage from the three-dimensional heart model, and calculate a central path between the first coordinate and the second coordinate; A section setting step is to drive the processor to set a section according to the second coordinate and the central path, wherein the section corresponds to a left atrial appendage opening, and the section intersects the central path at an intersection; A left atrial appendage parameter calculation step is to drive the processor to calculate a left atrial appendage parameter according to the left atrial appendage opening in the section; and An occluder determination step is to drive the processor to determine the size of a left atrial appendage occluder according to the left atrial appendage parameter. The left atrial appendage occluder determination method as described in claim 9, wherein the heart model establishment step includes: a region segmentation step, which drives the processor to convert the chest tomographic scan images into a plurality of heart region images according to a region growth algorithm; and a model generation step, which drives the processor to convert the heart region images into the three-dimensional heart model according to a marching block algorithm. The left atrial appendage occluder determination method as described in claim 9, wherein the center path calculation step comprises: an inscribed sphere radius calculation step, which drives the processor to calculate the multiple inscribed sphere radii of the three-dimensional heart model; and a calculation step, which drives the processor to calculate the center path according to a center path calculation rule, wherein the center path calculation rule conforms to the following formula: ; in represents the center path; represents the first coordinate; represents the second coordinate; Indicates the corresponding point one of the radii of the inscribed sphere; , and Represent points A coordinate value on an X-axis, a Y-axis, and a Z-axis. The left atrial appendage occluder determination method as described in claim 9, wherein the left atrial appendage parameter calculation step comprises: a contour marking step, which drives the processor to mark a left atrial appendage contour from the three-dimensional heart model according to the section; and a parameter calculation step, which drives the processor to calculate the left atrial appendage parameter according to the left atrial appendage contour.