TWI796222B - Visual spatial-specific response time evaluation system and method based on immersive virtual reality device - Google Patents

Abstract

A response evaluation system includes a headset device for providing image information to a subject, a control device for providing control signals, and a processing device including a storage unit and a processor. The storage unit stores program code, which causes the processor to execute: at a first time, displaying a first object image at a first position in a display area of the display of the headset, and calculating a first response time of the subject to the first object image according to a control signal provided by the control device; at the second time, displaying a second object image at a second position in the display area, and calculating a second response time of the subject to the second object image according to the control signal; and establishing a spatial position response time relationship according to the first position, the second position, the first response time and the second response time.

Description

System and method for evaluating visual-spatial-specific reaction time evaluation with immersive virtual reality equipment

The present invention relates to a response evaluation system and method; in particular, a response evaluation system and method for constructing a visual space with immersive virtual reality equipment to evaluate the subject's response ability in different visual spaces.

Visuo-spatial attention is an important cognitive ability, and it will decline with age, and it will be affected by brain injuries, including: (1) localized brain injuries (such as cerebral apoplexy, traumatic brain injury and and/or brain tumor); (2) generalized brain disease (eg, Parkinson's disease, hypoxic encephalopathy, and/or encephalitis); (3) degenerative changes (eg, dementia). Compared with motor or language impairments, visuospatial attention deficit is a common and high-impact problem that may be overlooked. For example, the proportion of visual neglect or inattention symptoms in stroke patients may be as high as 70%. These cases of stroke patients may have problems with recovery or poor/slow recovery after surgery due to impaired vision or concentration. Even if gradually improved through rehabilitation and other methods, the patient's remaining symptoms still have a significant impact on daily life function or safety. For example, in a case of mild hemi-neglect, although stimuli in both visual fields can still be noticed, the reaction speed may be slower on the patient's neglected side. However, the above-mentioned differences in individual cases often cannot be specifically quantified and evaluated.

Different from the evaluation of motor ability, the evaluation of visual and visual field response is not easy and objective. Traditionally, most of them rely on observing daily life behaviors or using paper tests. For example, in cases of cerebral apoplexy, commonly used paper-based tests are bisectional test, cancellation test to find specific patterns or letters on the paper, or imitation pattern, while behavioral observation is Take the test by reading a menu, making a phone call, or looking at a map. The above-mentioned known test methods need to rely on manual scoring or subjective judgment by medical personnel, resulting in error-prone and less objective results. At the same time, the paper or computer space of the test is limited, and it cannot reflect the multi-directional attention differences (near the central visual field or peripheral visual field, near and far) of the testees in life situations. In recent years, although computers or applications have been put into use, they can only optimize the manual scoring of medical personnel. There are still many difficulties in distinguishing or evaluating visuospatial abilities, such as hemi-neglect, hemianopia, and even fraudulent blindness.

In addition, the interference of the test environment and the patient's cognitive or motor ability will also affect the final test results. Specifically, visually "seeing" is not the same as cognitively "noticing" and "activating a motor response". For example, if the left side ignores the stimulation of the left visual field, the patient may not pay much attention to it, and may also be slow to start the movement response. Dementia patients may see and notice, but the start movement is slowed down, deliberately pretending not to see In some cases, visual attraction to a stimulating object can be measured, but intentional inaction. The current known technology can only measure whether there is a response to the completed movement, but cannot analyze the magnitude or speed of the response to the stimulus in different stages such as vision and movement.

The different stimulus characteristics (eg, color, shape and/or size) and the interference of the surrounding environment will affect the patient's ability to pay attention. Using physical or paper tests, the selectivity of the stimulus characteristics is limited. Even if the test environment is built using a computer, the visual and sound interference from the surrounding environment may still affect the test results.

Therefore, in this field, how to provide testees with a test environment that avoids surrounding disturbances, effectively provide different test situations or stimuli, and provide efficient and objective scoring methods will be issues that must be overcome.

The invention provides a response evaluation system, which includes a head-mounted device for providing image information to a subject, a control device for providing control signals, and a processing device including a storage element and a processor. The storage element stores the program code, and the program code causes the processor to execute: at the first time, display the first object image at the first position in the display range of the head-mounted device, and calculate the subject's response to the first object image The first response time of the control signal provided by the control device. At the second time, the second object image is displayed at the second position in the display range, and the second reaction time for the subject to provide a control signal by the control device to the second object image is calculated. And according to the first position, the second position, the first response time and the second response time, a spatial position-response time relationship is established.

The present invention provides a response evaluation method, comprising: providing an image to a subject through a display of a head-mounted device; at a first time, displaying a first object image at a first position in the display range of the display of the head-mounted device, and calculating The subject's first reaction time to the first object image provided by the control device with a control signal. At the second time, the second object image is displayed at the second position in the display range, and the second reaction time for the subject to provide a control signal by the control device to the second object image is calculated. And according to the first position, the second position, the first response time and the second response time, a spatial position-response time relationship is established.

As mentioned above, the tester is provided with a better and less distracting test environment through the head-mounted device, and the control device is used to provide feedback, so as to evaluate the tester's reaction speed and line of sight deviation, so as to achieve effective measurement As well as the use of objective values to evaluate the subject's field of vision, concentration and other purposes.

Any reference to an element herein using a designation such as "first," "second," etc. generally does not limit the number or order of those elements. Rather, these designations are used herein as a convenient way of distinguishing between two or more elements or instances of an element. Therefore, it should be understood that designations "first", "second", etc. in the claims do not necessarily correspond to the same designations in the written description. Furthermore, it should be understood that references to first and second elements do not mean that only two elements may be used or that the first element must precede the second element. "Includes", "including", "has", "containing" and so on used in this article are all open terms, meaning including but not limited to.

The term "coupled" is used herein to refer to a direct or indirect electrical coupling between two structures. For example, in one example of indirect electrical coupling, one structure may be coupled to another structure via a passive element such as a resistor, capacitor, or inductor.

In the present invention, the words "exemplary" and "for example" are used to mean "serving as an example, instance or illustration". Any implementation or aspect described herein as "exemplary" or "such as" is not necessarily to be construed as preferred or advantageous over other aspects of the invention. The terms "about" and "approximately" as used herein with respect to a stated value or characteristic are intended to mean within a certain value (eg, 10%) of the stated value or characteristic.

Please refer to FIG. 1. FIG. 1 illustrates a response evaluation system 100, including a head-mounted device 110 for providing image information to a subject 10, a control device 130 for providing control signals, and a processing device including a storage element and a processor. 120. The storage element stores program codes, and the program codes enable the processor to execute the response evaluation method of the present invention.

Specifically, as shown in FIG. 2A , the head-mounted device 110 (for example, virtual reality glasses or smart glasses) can have a housing 114, and can be worn by the subject on the head (for example, has a bracket that can be fixed on ear shell or strap style). And preferably, the housing 114 can provide the subject to block the light outside the display 111 of the head-mounted device 110 to avoid interference from the surrounding environment. The display 111 of the head-mounted device 110, for example, can have dual displays corresponding to both eyes of the subject respectively, so that applications such as single-eye testing can be provided; or, it can be a single display to provide a relatively complete response speed/ Field of view test environment. However, the number of displays 111 of the head-mounted device 110 is not limited to the above examples, and the number of displays 111 can be adjusted according to requirements, and is not limited to the above examples. On the other hand, the head-mounted device 110 may also include a sound output/input device 116 (for example, an earphone or a microphone), so that the subject can receive instructions or respond to instructions. In addition, the sound output/input device 116 can also be equipped with a noise reduction setting (which can be active noise reduction or passive noise reduction), so as to avoid the subject being disturbed by the surrounding environment sound.

On the other hand, as shown in FIG. 2B , the processing device 120 can be, for example, a computer, a smart phone, a tablet computer, or a microcomputer system integrated with the head-mounted device 110 , but is not limited thereto. The processing device 120 can be communicatively coupled with the head-mounted device 110 through wired (eg, signal cable) or wireless (eg, bluetooth, wireless network, or infrared) and other means. In general, the processing device 120 can also be coupled to the display 124 to generate a user interface or reflect the running status of the test for the operator to confirm. In some cases, the processing device 120 may also have an external input 126 such as a keyboard, a mouse, or a touch panel to allow an operator to control or monitor the processing device, but is not limited thereto. The processor 122 of the processing device 120 is, for example, a central processing unit (CPU), a field programmable gate array (FPGA), an application specific integrated circuit (ASIC) or a system on a chip (SoC) with computing capability and capable of executing programs. On the other hand, the storage element 121 is, for example, an element capable of storing data such as a memory, a read only memory (ROM) or a flash memory. The storage element 121 stores codes or application programs that can be executed by the processor 122 . It should be noted that the present invention is not limited to the form and type of the processor 122, the storage element 121 and/or the program code.

Regarding the control device 130 , please refer to FIGS. 3A-3B . The control device 130 can be, for example, a handle, a button, a voice-activated switch and/or an attitude detector, etc., which can provide feedback to the processing device 120 for the subject. Specifically, when the subject is performing a test, the control device 130 may issue commands such as confirmation, activation, cancellation, and suspension to the processing device. For example, when the control device 130 is a button or a handle, the subject can provide a signal to the processing device 120 by pressing the button, so that the test can be started, proceed to the next step or pause. On the other hand, the control device 130 does not necessarily need to be in contact with the subject, for example, the purpose of receiving/giving instructions can be achieved by capturing the gesture or movement of the subject through voice control or an attitude meter.

It should be noted that, as shown in FIG. 3A , the control device 130 may be directly or indirectly coupled to the processing device 120 . For example, the control device 130 can be directly connected to the processing device 120 through wired (eg, signal cable, network cable) or wireless (eg, wireless network, bluetooth, infrared) manner. On the other hand, as shown in FIG. 3B , the control device 130 may be connected to the processing device 120 through the head-mounted device 110 . In other words, after the control device 130 is connected to the head-mounted device 110 , the signal of the control device 130 is provided to the processing device 120 through the head-mounted device 110 . It should be understood, however, that the present invention is not limited to the above examples.

In one embodiment, the control device 130 may include an eye tracking module. Specifically, the control device 130 can be integrated with the head-mounted device 110, and the eye tracking module can be set on the side of the housing 114 facing the subject, so as to detect the subject's eye image or correlate with the eye sight. electrical and/or magnetic signals. The eye tracking module can, for example, use the electro-oculography, the scleral search coil, the video-oculo graph, or the combined analysis of the pupil and cornea (Video Based Combined Pupil/Corneal Reflection) and other eye-tracking technologies to track the subject's gaze direction.

The eye tracking module can convert the projection trajectory information projected by the subject's line of sight onto the display area DA of the display 111 of the head-mounted device 110 into control signals and provide them to the processing device 120 for subsequent processing. Specifically, when the subject aligns his/her gaze at a preset position (such as the center or a corner) in the display area DA, the determination of the control signal can be given. For example, start when looking at the center or pause when looking at the corner or any other possible command. In this way, the subject can have an interface to input feedback or control signals to the processing device 120 through the line of sight and/or eye movement track, without redundant devices or configurations.

The program code stored in the storage element 121 enables the processor 122 to execute the reaction evaluation method of the present invention: at the first time t1, the first object image I1 is displayed at the first position P1 in the display range DA of the display 111, and the measured object image I1 is calculated. or the first reaction time RT1 for the first object image I1; at the second time t2, the second object image I2 is displayed at the second position P2 in the display range DA of the display 111, and the subject’s response to the second object image is calculated. The second response time RT2 of I2; and establishing a spatial position-response time relationship according to the first response time RT1 and the second response time RT2.

More specifically, as shown in Figure 4A, when the test starts, the subject's line of sight can be at the initial position P0. Specifically, the initial position P0 of the line of sight can be adjusted to the center by the subject before the test begins. Gaze position, or any position before the start of the test. When the subject is ready, the operator can execute the start command or the subject can start it by himself (for example, inputting a control signal through the control device 130 ). When the first position P1 in the display area DA of the display 111 displays the first object image I1, if the subject receives the stimulation of the first object image I1, for example, the subject's line of sight moves from the initial position P0 to the first object image I1. The first position P1 where the object image I1 is located, or the subject notices the first object image I1 through peripheral vision when keeping the line of sight at the initial position P0. At this time, the subject can input a confirmation signal through the control device 130 for the first reaction time RT1 of the first object image I1 . For example, after the subject sees/notices the image I1 of the first object (whether it is viewed directly or from the peripheral vision), the control device 130 immediately generates a control signal to confirm the timing.

Next, as shown in FIG. 4B, when the timing of the first reaction time RT1 is completed or after a preset time from the first time t1, the second object image will be displayed at the second position P2 in the display range of the display. I2 (at this time, the first object image I1 has disappeared). In other words, there is a preset time interval between the first time t1 and the second time t2 (the preset time can be defined by the system or the operator), or the second time is roughly equal to the first time t1 plus the first reaction time RT1 ( That is, the second object image I2 is generated immediately after the first reaction time RT1 is determined).

At the second time t2, after the second object image I2 is displayed at the second position P2, if the subject receives the stimulus of the second object image I2, for example, the subject's line of sight will move from the current position P0' to the second object image. The second position P2 where the object image I2 is located, or the subject notices the second object image I2 through peripheral vision when keeping the line of sight at the current position P0 ′. Like the measurement method of the first reaction time RT1 , the subject can input a confirmation signal through the control device 130 . It should be noted that the current position P0' can be the first position P1 (including any position within the predetermined range A1), the initial position P0, or any position where the subject's line of sight is before the second object image I2 is generated .

The above-mentioned relationship between the first position P1 and the second position P2 may be generated randomly or sequentially. For example, the first object image I1 may be randomly displayed at the first position P1 in the display area DA of the display 111 , and then the second object image I2 may be randomly displayed at the second position P2 . Generally speaking, the first position P1 and the second position P2 do not overlap (or can partially overlap), and preferably, the second position P2 can be a predetermined distance away from the first position P1. It should be noted that the distance and/or position within the display area DA referred to herein may use pixels of the display 111 as a unit (for example, a certain distance pixel (pixel)). In one embodiment, the display range DA can be divided into four quadrants Phase 1-4, when the first position P1 appears in one of the four quadrants Phase 1-4 in a preset or random manner (this embodiment is the second quadrant, Phase 2), then the second position may appear in one of the remaining three quadrants (in this embodiment, the fourth quadrant, Phase 4) in a preset or random manner.

On the other hand, the first position P1 and/or the second position P2 can also be controlled by an operator or a system (eg, artificial intelligence) to select the appearance position. For example, at the moment of the test, the operator decides the position where the next image will appear, or before the test, the operator sets the schedule of the image position in advance in a preset manner. It should be noted that, in order to avoid too much confusion in the illustration, this embodiment only illustrates the first position P1 and the second position P2. However, those skilled in the art should know that three or more images can be generated in the present invention Location. For example, the third position P3 displaying the third object image I3 may not overlap or only partially overlap with the second position P2. However, in some cases, the third position P3 may overlap or partially overlap with the first position P1 (ie, the third object image I3 appearing at the third position P3 may overlap or be close to the first object image I1 ).

In addition, please refer to FIGS. 4A-4B together. In an embodiment where the control device 130 may include an eye tracking module, the first reaction time RT1 of the subject to the first object image I1 can be measured through the eye tracking module. Automatic measurement. For example, when the subject sees/notices the first object image I1, the eye tracking module tracks the subject's line of sight to within a predetermined range A1 from the first position P1 to automatically determine the first reaction time RT1. It should be noted that the range size of the predetermined range A1 may be different according to the test difficulty or other conditions. For example, when the predetermined range A1 is "zero", it means that the subject needs to completely overlap the line of sight position with the first position P1 before he can judge to see, and vice versa, when the predetermined range A1 is larger, there will be more lenient judgment. Next, at the second time t2, after the second object image I2 is displayed at the second position P2, the eye tracking module can be used to determine whether the subject's line of sight has moved within a predetermined range A2 from the second position P2, so as to Record the second reaction time RT2. It should be noted that the predetermined range A1 and the predetermined range A2 may be the same or different.

On the other hand, the gaze track information L1, L2 captured by the eye tracking module can also be provided to the operator through the display 124 of the processing device 120, and the operator can use the gaze track information L1, L2 displayed on the display 124 to confirm the received eye position of the tester for active timing. For example, when the operator sees that the subject's line of sight moves to within a predetermined range A1 from the first position P1, the operator immediately presses OK to start timing. It should be noted that the above-mentioned timing methods for the reaction times RT1 and RT2 are not intended to limit the present invention, and any timing means known in the art shall fall within the scope of the present invention.

In one embodiment, please refer to FIG. 5 , the object images may appear in the display area DA of the display 111 sequentially in a random or non-random manner until all object images have been displayed in the display area DA. Specifically, as shown in FIG. 5 , if the display area DA of the display 111 can be divided into N sub-districts, the object images will appear sequentially in the N sub-divisions in the above example. In this embodiment, at least N sets of response time data will be generated. It should be noted that the above N sub-regions may be distributed within the display area DA of the display 111 in a manner of overlapping, partially overlapping and/or not overlapping at all. The present invention is not limited to the way of dividing the cells of the display area DA of the display 111 . It should be noted that the display area DA used in FIG. 5 is a circle, however, it should be understood that the display area can also be a rectangle or any suitable shape. In addition, the division of cells is not limited to the rectangle shown in FIG. 5 .

On the other hand, the first object image I1 and the second object image I2 may be completely the same or different. For example, the first object image I1 and the second object image I2 may be different in size, shape, color and/or brightness. The tester can adjust each object image according to the different purposes of the test. For example, when it is necessary to generate N object images in total, the N images may be completely the same or at least one of them may be different.

After the test is over, in the display range DA of the display 111 , each of the N positions will have corresponding reaction time data (at least N sets of reaction time data). In this way a spatial position-reaction time relationship can be established. It should be noted that the response time in the spatial position-response time relationship can be the original data stored during the measurement, or the data after normalization or weighting operation. For example, the average reaction speed of the subject can be set as the reference value, and by comparing the reaction time of each position with the reference value, it can be obtained that the subject is relatively easy to ignore. In addition, the reference value of the reaction time can also be the average of all the subjects, or any other statistical value.

In one embodiment, as shown in FIG. 6 , the response evaluation system 100 can generate a response time spectrogram according to the spatial position-reaction time relationship. Specifically, the plane formed by the X-axis and Y-axis of the reaction time spectrogram can correspond to the field of vision of the subject, and each point on the graph has a Z-axis value corresponding to the reaction speed of the subject. Axis values can represent 2D images in terms of color scale (eg, a blue-to-red color temperature map), grayscale, and/or brightness differences. The 3D image information can also be presented in a manner such as a histogram. It should be noted that the present invention is not limited to the form of the response time spectrogram in the above example.

In one embodiment, the processing device 120 can also calibrate the plurality of response times stored during the test. For example, during the test, each of the total N positions will have corresponding reaction time data. When the subject is tested for M times (M is less than N), there may be a slight delay (for example, a few milliseconds) in the reaction time after the Mth time due to fatigue or burnout. When the subject is fatigued or tired (for example, it can be determined through the processing device 120, through the preset number of tests and/or other possible ways), the reaction time is corrected. The correction method can be incremental (increase the length of the correction reaction time as the number of tests increases), linear, and nonlinear. In one embodiment, the calibration system can refer to the reaction time at the same point. For example, after recording the reaction time RT _r of the subject's line of sight from the reference starting point to the reference end point during the initial measurement of the test, after the Mth test, measure the reaction time of the subject's line of sight from the reference starting point to the reference end point again. After the reaction time RT _Mr , the reaction time at the initial stage of the test and after M measurements is corrected by the ratio, difference or arbitrary relationship between the reaction time RT _r and the reaction time RT _Mr. It should be noted that after several tests, it is also possible that the subject's reaction becomes faster after being familiar with the test procedure, so the correction of the reaction time can also be performed by decreasing or other methods.

FIG. 7 illustrates a simplified flowchart 700 for constructing reaction time and eye movement distribution maps for different spatial locations through reaction time data and eye movement trajectories. Firstly, after the object is generated at the spatial position 1, at this time, the subject will go through various stages such as seeing with the eyes, making a response in the brain, and completing the response. After the system can record the subject's eye movement track and reaction time, it can output to the back-end calculation. Next, repeat the action at spatial position 2. After reaching the spatial position N, N sets of eye movement trajectories and N sets of reaction times will be stored, corresponding to the respective spatial positions 1-N. Then, based on the spatial positions 1-N, eye movement trajectories 1-N and reaction time 1-N, the distribution diagrams of reaction time and eye movement trajectories in different spatial positions are established.

In one embodiment, as shown in FIG. 8, FIG. 8 illustrates a reaction evaluation method 800, including: step 810, providing images to the subject through the display of the head-mounted device; step 820, at the first time, The first position in the display range of the display of the device displays the first object image, and calculates the subject's first reaction time for the first object image to control the device to provide a control signal; step 830, at the second time, in the display range The second position in the display shows the second object image, and calculates the second reaction time for the subject to provide the control signal with the control device for the second object image; and step 840, according to the first position, the second position, and the first reaction time With the second reaction time, a spatial position-reaction time relationship is established.

In one embodiment, the method further includes: step 850, generating a response time spectrogram according to the spatial position-response time relationship.

In one embodiment, the method further includes: Step 835, performing calibration processing on at least one of the first response time and the second response time.

The previous description of the invention is provided to enable one of ordinary skill in the art to make or practice the invention. Various modifications to the invention will be readily apparent to those skilled in the art, and the generic principles defined herein may be applied to other changes without departing from the spirit or scope of the invention. Thus, the present invention is not intended to be limited to the examples described herein but is to be accorded the widest scope consistent with the principles and novel features of the invention herein.

10: Subject 100: Response Evaluation System 110: Headset 111: display 114: Shell 116: Sound output/input device 120: processing device 121: storage element 122: Processor 124: display 126: External input 130: Control device 700: process 800: Response Assessment Methods 810, 820, 830, 835, 840, 850: steps A1, A2: Scheduled range DA: display range I1: first object image I2: second object image t1: the first time t2: second time RT1: First Response Time RT2: second reaction time L1, L2: Line of sight trajectory P0: initial position P0': current position P1: first position P2: second position

The drawings are presented to help describe various aspects of the present invention. In order to simplify the drawings and highlight the contents to be presented in the drawings, the known structures or elements in the drawings may be drawn in a simple schematic manner or presented in an omitted manner . For example, the number of elements may be singular or plural. These figures are provided merely to illustrate these aspects and not to limit them.

Fig. 1 is an example situation diagram of using a response evaluation system in an embodiment of the present invention.

FIG. 2A is a schematic diagram of a head-mounted device according to an embodiment of the present invention.

FIG. 2B is a schematic diagram and a system block diagram of a processing device in an embodiment of the present invention.

3A-3B are system block diagrams of a coupling between a processing device and a control device in an embodiment of the present invention.

4A-4B are schematic diagrams of the relationship between object images and display areas in an embodiment of the present invention.

FIG. 5 is a schematic diagram of dividing the display range into N cells in an embodiment of the present invention.

FIG. 6 is a schematic diagram of a response time spectrogram in an embodiment of the present invention.

FIG. 7 is a simplified flow chart of establishing the distribution diagrams of reaction time and eye movement trajectories at different spatial locations in an embodiment of the present invention.

FIG. 8 is a flowchart of a response evaluation method in an embodiment of the present invention.

10: Subject

100: Response Evaluation System

110: Headset

120: processing device

130: Control device

Claims (12)

A response assessment system comprising: A head-mounted device for providing an image information to a subject; a control device for providing a control signal; and A processing device includes a storage element and a processor, the storage element stores a program code, and the program code causes the processor to execute: At a first time, display a first object image at a first position in a display range of the display of the head-mounted device, and calculate the subject's response to the first object image and provide the control signal with the control device a first reaction time; displaying a second object image at a second position in the display range at a second time, and calculating a second reaction time for the subject to provide the control signal with the control device to the second object image; as well as According to the first position, the second position, the first response time and the second response time, a spatial position-response time relationship is established. As the reaction evaluation system of claim 1, wherein the control device further includes: The eyeball tracking module provides the control signal according to a gaze position of the subject. The response evaluation system according to claim 1, wherein the display range is divided into quadrants, the first position corresponds to a first quadrant of the display range, and the second position corresponds to any one of the remaining quadrants. The response evaluation system according to claim 1, wherein the second position randomly appears in a position in the display range that does not overlap with the first position. The response evaluation system according to claim 1, wherein the program code further causes the processor to execute: According to the spatial position-response time relationship, a response time spectrogram is generated. The response evaluation system according to claim 1, wherein the processing device performs a calibration process on at least one of the first response time and the second response time. A response assessment method comprising: providing an image to a subject through a head-mounted device; At a first time, display a first object image at a first position in a display range of the display of the head-mounted device, and calculate that the subject provides a control signal to the first object image with a control device a first reaction time; displaying a second object image at a second position in the display range at a second time, and calculating a second reaction time for the subject to provide the control signal with the control device to the second object image; as well as According to the first position, the second position, the first response time and the second response time, a spatial position-response time relationship is established. As the response evaluation method of claim 7, wherein the control device further includes: The eyeball tracking module provides the control signal according to a gaze position of the subject. The response evaluation method according to claim 7, wherein the display range is divided into quadrants, the first position corresponds to a first quadrant of the display range, and the second position corresponds to any of the remaining quadrants. The response evaluation method according to claim 7, wherein the second position randomly appears in a position in the display range that does not overlap with the first position. Such as the response evaluation method of claim item 7, which also includes: According to the spatial position-response time relationship, a response time spectrogram is generated. Such as the response evaluation method of claim item 7, which also includes: A calibration process is performed on at least one of the first response time and the second response time.

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