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TWI653335B - Poly-gamma-glutamic acid production method - Google Patents

Poly-gamma-glutamic acid production method Download PDF

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Publication number
TWI653335B
TWI653335B TW106127472A TW106127472A TWI653335B TW I653335 B TWI653335 B TW I653335B TW 106127472 A TW106127472 A TW 106127472A TW 106127472 A TW106127472 A TW 106127472A TW I653335 B TWI653335 B TW I653335B
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TW
Taiwan
Prior art keywords
bacillus subtilis
pga
strain
concentration
medium
Prior art date
Application number
TW106127472A
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English (en)
Chinese (zh)
Other versions
TW201812014A (zh
Inventor
澤田和久
田向敦子
Original Assignee
日商花王股份有限公司
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Application filed by 日商花王股份有限公司 filed Critical 日商花王股份有限公司
Publication of TW201812014A publication Critical patent/TW201812014A/zh
Application granted granted Critical
Publication of TWI653335B publication Critical patent/TWI653335B/zh

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    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N1/00Microorganisms, e.g. protozoa; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
    • C12N1/20Bacteria; Culture media therefor
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N1/00Microorganisms, e.g. protozoa; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
    • C12N1/20Bacteria; Culture media therefor
    • C12N1/205Bacterial isolates
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12PFERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P13/00Preparation of nitrogen-containing organic compounds
    • AHUMAN NECESSITIES
    • A23FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23LFOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES, NOT OTHERWISE PROVIDED FOR; PREPARATION OR TREATMENT THEREOF
    • A23L33/00Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
    • A23L33/10Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/74Synthetic polymeric materials
    • A61K31/785Polymers containing nitrogen
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/66Microorganisms or materials therefrom
    • A61K35/74Bacteria
    • A61K35/741Probiotics
    • A61K35/742Spore-forming bacteria, e.g. Bacillus coagulans, Bacillus subtilis, clostridium or Lactobacillus sporogenes
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/72Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds
    • A61K8/84Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds obtained by reactions otherwise than those involving only carbon-carbon unsaturated bonds
    • A61K8/88Polyamides
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/96Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
    • A61K8/99Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution from microorganisms other than algae or fungi, e.g. protozoa or bacteria
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • A61P3/06Antihyperlipidemics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09Recombinant DNA-technology
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12RINDEXING SCHEME ASSOCIATED WITH SUBCLASSES C12C - C12Q, RELATING TO MICROORGANISMS
    • C12R2001/00Microorganisms ; Processes using microorganisms
    • C12R2001/01Bacteria or Actinomycetales ; using bacteria or Actinomycetales
    • C12R2001/07Bacillus
    • C12R2001/125Bacillus subtilis ; Hay bacillus; Grass bacillus

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  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Biotechnology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Genetics & Genomics (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • General Engineering & Computer Science (AREA)
  • Microbiology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Biomedical Technology (AREA)
  • Virology (AREA)
  • Medicinal Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Coloring Foods And Improving Nutritive Qualities (AREA)
  • Cosmetics (AREA)
TW106127472A 2016-08-25 2017-08-14 Poly-gamma-glutamic acid production method TWI653335B (zh)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP2016165099A JP6371810B2 (ja) 2016-08-25 2016-08-25 ポリ−ガンマ−グルタミン酸の生産方法
JP??2016-165099 2016-08-25

Publications (2)

Publication Number Publication Date
TW201812014A TW201812014A (zh) 2018-04-01
TWI653335B true TWI653335B (zh) 2019-03-11

Family

ID=61245757

Family Applications (1)

Application Number Title Priority Date Filing Date
TW106127472A TWI653335B (zh) 2016-08-25 2017-08-14 Poly-gamma-glutamic acid production method

Country Status (4)

Country Link
JP (1) JP6371810B2 (ja)
CN (1) CN109477123B (ja)
TW (1) TWI653335B (ja)
WO (1) WO2018037833A1 (ja)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN110747240A (zh) * 2019-12-01 2020-02-04 内蒙古阜丰生物科技有限公司 一种聚谷氨酸的发酵工艺
CN110904012B (zh) * 2019-12-19 2021-09-24 华熙生物科技股份有限公司 一株枯草芽孢杆菌及其在生产γ-聚谷氨酸中的应用
CN113583895B (zh) * 2021-06-28 2023-02-17 杨凌未来中科环保科技有限公司 一株枯草芽孢杆菌、有机肥、生产方法及应用
CN115786177B (zh) * 2021-11-11 2024-08-09 华中农业大学 一种解淀粉芽胞杆菌dt5及其应用

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP3547839B2 (ja) * 1995-03-14 2004-07-28 キッコーマン株式会社 ガンマーポリグルタミン酸の生産法
KR20010078440A (ko) * 2001-01-11 2001-08-21 김형순,성문희 고분자량의 폴리-감마-글루탐산을 생산하는 내염성 균주바실러스 서브틸리스 청국장
KR100399091B1 (en) * 2002-07-10 2003-09-22 Bioleaders Corp Macromolecular weight poly(gamma-glutamic acid) and its use
JP4659781B2 (ja) * 2007-04-25 2011-03-30 株式会社ミツカングループ本社 新規納豆菌、及び該納豆菌を用いて製造された柔らかい納豆
CN101875910A (zh) * 2010-04-20 2010-11-03 山东省食品发酵工业研究设计院 一株产γ-聚谷氨酸的解淀粉芽孢杆菌
CN101948785B (zh) * 2010-08-31 2012-06-13 南京医科大学 一株γ-聚谷氨酸产生菌及利用其制备γ-聚谷氨酸及其盐的方法
JP6388388B2 (ja) * 2013-09-03 2018-09-12 花王株式会社 ポリ−ガンマ−グルタミン酸の生産方法
CN104087628A (zh) * 2014-04-28 2014-10-08 广西大学 一种降低γ-聚谷氨酸发酵液粘度的方法

Also Published As

Publication number Publication date
JP2018029546A (ja) 2018-03-01
TW201812014A (zh) 2018-04-01
WO2018037833A1 (ja) 2018-03-01
CN109477123B (zh) 2020-07-10
CN109477123A (zh) 2019-03-15
JP6371810B2 (ja) 2018-08-08

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