TWI643599B - Standing bio-impedance measuring method and device thereof - Google Patents

Abstract

A stand-up bioimpedance measurement method mainly involves allowing a subject to contact a first electrode group and a second electrode group with two of the limbs in a standing posture, and then to the first and second electrode groups. One of the inputs is measured by a current, and the current is measured by the other of the first and second electrode sets, so that a single hand-to-foot, single-handed opponent, single-foot-to-foot or integrated multi-limb segment can be derived. In the measurement mode, after the measurement is completed, the resistance value and the capacitance resistance value of the tested part are calculated. Finally, an electrical impedance spectrum analysis method is used to obtain a phase angle, and the subject can use the measurement result as a basis for judging the physiological condition. The foregoing process can be completed by itself, and does not need to be assisted by others, thereby achieving the purpose of increasing convenience and practicability.

Description

Standing bio-impedance measuring method and device thereof

The invention relates to bioimpedance measurement technology, in particular to a standing bioimpedance measurement method and a measurement device used in the method.

The basic structural unit of the human body is a cell, and the cells are bathed in an extracellular fluid. The cell itself contains a cell membrane and an intracellular fluid. The extracellular fluid and the intracellular fluid contain a plurality of ions, and thus have electrical conductivity and are close in electrical properties. In the resistance, and the main component of the cell membrane is a lipid bilayer, there is no direct current conductivity, but the alternating current can pass, so it is equivalent to a capacitor and has a capacitive reactance. Once there is current through the body, the current is mainly through non-fatty tissue (such as muscles, organs, blood vessels, blood or body fluids, etc.), because non-fatty tissue has much less electrical impedance than adipose tissue, so it can be used between different tissues. The structural composition of the human body is measured for the difference in electrical impedance.

In the conventional bioimpedance measurement technique, a safe alternating current is input to the subject by means of an electrode adhered to the surface of the skin during measurement, and the corresponding resistance and capacitance are measured by the alternating current, and then according to The measurement results further calculate the phase angle (such as φ shown in Figure 1), which is used in many studies as a disease prognosis or age-related indicator when the body is affected by certain diseases (such as heart failure, kidney). When the condition of the nutrient state or moisture is affected by failure or cirrhosis, the angle of the phase angle changes.

However, in the conventional bio-impedance measurement technique described above, the subject is mainly measured by lying on his back. Simply put, let the subject lie flat and then discharge the two The electrode is placed where the AC power is going to enter the body (such as the wrist), and the other two receiving electrodes are placed at the corresponding line of the first two electrodes (such as the ankle), and then the current is input to the subject, and the current will enter from the wrist. And collect the signal on the ankle, so that the resistance and the capacitive reactance can be measured, and finally the phase angle is further calculated according to the resistance and the capacitance resistance. However, in the case of reclining measurement, the subject needs to have a test bed that can lie flat and has an insulating surface, and at the same time, an assistant assists the electrode to be attached and the operation of the instrument, so in practical application. There are still certain restrictions.

The main object of the present invention is to provide a standing bio-impedance measurement method which can simplify the process of measuring the reclining type, thereby increasing the convenience and practicability in measurement.

In order to achieve the above object, the measuring method of the present invention comprises the following steps. Firstly, a bioimpedance measuring device is provided, the bioimpedance measuring device having at least a first electrode group and at least a second electrode group, and then maintaining a subject in a standing posture and allowing the subject to use the limbs Two of them respectively contact the first and second electrode groups of the bioimpedance measuring device, and then input a measuring current to one of the first and second electrode groups of the bioimpedance measuring device, and the biological The other one of the first and second electrode groups of the impedance measuring device receives the measuring current, and finally calculates the resistance value and the capacitance resistance value of the measured portion of the subject, and then obtains a phase angle according to the calculation result.

In the present invention, the subject can contact the first and second electrode groups of the bio-impedance measuring device with both hands to measure the resistance values and capacitance values of the left and right upper limbs.

In the present invention, the subject can contact the first and second electrode groups of the bioimpedance measuring device with both feet to measure the resistance value and the capacitance resistance value of the left and right lower limbs.

In the present invention, the subject can use one of the hands to contact the first electrode group of the bioimpedance measuring device, and then one of the feet contacts the second electrode group of the bioimpedance measuring device, thereby measuring Resistance values and capacitance values of the left upper limb, trunk and left lower limb or right upper limb, trunk and right lower limb.

In the present invention, the biometric measuring device has two first electrode groups and one second electrode group, and the subject uses one of the hands and one of the legs to respectively contact the first electrode group, and then reuses The other hand contacts the second electrode group to measure the resistance value and the capacitance value of the left and right upper limbs.

In the present invention, the biometric measuring device has two first electrode groups and one second electrode group, wherein one of the hands of the subject and one of the feet respectively contact the first electrode group, The other foot of the tester contacts the second electrode group to measure the resistance value and the capacitance resistance value of the left and right lower limbs.

In the present invention, the biometric measuring device has two first electrode groups and two second electrode groups, and the subject uses one of the hands and one of the legs to respectively contact the first electrode group, and then reuses The other hand and the other foot are respectively in contact with the second electrode group, thereby measuring the resistance value and the capacitance resistance value of the entire trunk.

In the present invention, since the subject's water is subjected to gravity and concentrated in the lower limb when standing, the measurement result may be inaccurate, and thus the resistance value and the capacitance resistance value may be further corrected in calculation. The resistance value is calculated by the following formula: R _i ( t ) = C ₁ ( t ) + C ₂ (t) × R , and the capacitance resistance value is calculated by the following formula: C ₄ (t) × X _c , the phase angle is calculated by the following formula: , where R _i is the corrected resistance value, and R is the resistance value obtained by actual measurement. For the corrected capacitance value, X _c is the capacitance value obtained by the actual measurement, t is time, C ₁ ~ C ₄ is the correction compensation function, and φ _i is the phase angle.

A second object of the present invention is to provide a bioimpedance measuring device used in the foregoing method, which has a pedal platform, a pair of handles connected to the pedal platform, and a switch connecting the pedal platform and each of the handles. The pedal platform has a first electrode group and a second electrode group, wherein the handle has a first electrode group, and the other handle has a second electrode group. Thereby, the hands of the subject can contact the first and second electrode groups of the pair of handles, and the feet of the subject can contact the first and second electrode groups of the pedal platform, and can also be according to The actual needs of the choice of hands, feet, one-handed feet, one-handed feet, one-handed feet or both hands and feet, the entire process does not need to help others, thus increasing the convenience and practicality of use .

The detailed construction, features, assembly or use of the present invention will be described in the detailed description of the embodiments. However, it should be understood by those of ordinary skill in the art that the present invention is not limited by the scope of the invention.

10‧‧‧Bioimpedance measuring device

20‧‧‧foot platform

21‧‧‧First electrode group

22‧‧‧First discharge electrode

23‧‧‧First receiving electrode

24‧‧‧Second electrode group

25‧‧‧Second discharge electrode

26‧‧‧second receiving electrode

30‧‧‧Left handle

31‧‧‧First electrode group

32‧‧‧First discharge electrode

33‧‧‧First receiving electrode

40‧‧‧right handle

41‧‧‧Second electrode group

42‧‧‧Second discharge electrode

43‧‧‧second receiving electrode

50‧‧‧Toggle switch

60‧‧ ‧ subjects

61‧‧‧left upper limb

62‧‧‧ right upper extremity

63‧‧‧ Left lower limb

64‧‧‧ right lower extremity

65‧‧‧ Torso

Figure 1 shows the Cole-Cloe Plot for resistance and capacitance.

Figure 2 is a flow chart of the bioimpedance measurement method of the present invention.

Figure 3 is a block diagram of the bioimpedance measuring device of the present invention.

Fig. 4 is a schematic diagram showing the measurement of the bioimpedance measurement method of the present invention, mainly showing the measurement method of the hand opponent.

Fig. 5 is a schematic diagram showing the measurement of the bioimpedance measurement method of the present invention, mainly showing the method of measuring the foot to the foot.

Fig. 6 is a schematic view showing the measurement of the bioimpedance measurement method of the present invention, mainly showing the measurement methods of the right upper limb, the trunk and the right lower limb.

Fig. 7 is a schematic view showing the measurement of the bioimpedance measurement method of the present invention, mainly showing the measurement methods of the left upper limb, the trunk and the left lower limb.

Fig. 8 is a schematic view showing the measurement of the bioimpedance measurement method of the present invention, mainly showing the measurement method of the left upper limb.

Fig. 9 is a schematic view showing the measurement of the bioimpedance measurement method of the present invention, mainly showing the measurement method of the right upper limb.

Fig. 10 is a schematic view showing the measurement of the bioimpedance measurement method of the present invention, mainly showing the measurement method of the left lower limb.

Figure 11 is a schematic diagram of the measurement of the bioimpedance measurement method of the present invention, mainly showing the measurement method of the right lower limb.

Fig. 12 is a schematic view showing the measurement of the bioimpedance measurement method of the present invention, mainly showing the measurement method of the trunk.

Please refer to FIG. 2 first. The bioimpedance measurement method of the present invention includes the following steps:

a) A bio-impedance measuring device 10 is provided. In the present embodiment, the bio-impedance measuring device 10 has a pedal platform 20, a left handle 30, a right handle 40 and a switch 50. As shown in FIG. 3, the pedal platform 20 has a first electrode group 21 and a second electrode group 24. The first electrode group 21 corresponds to the right foot of the subject 60 and has a first discharge electrode 22 and a The first receiving electrode 23, the second electrode group 24 corresponds to the left foot of the subject 60 and has a second discharging electrode 25 and a second receiving electrode 26; the left handle 30 is connected to the pedal platform 20 and has a first electrode Group 31, the first electrode group 31 has a first discharge electrode 32 and a first receiving electrode 33, the right handle 40 is connected to the foot platform 20 and has a second electrode group 41, and the second electrode group 41 has a second discharge. The electrode 42 and the second receiving electrode 43 are connected to the pedal platform 20, the left handle 30 and the right handle 40 for switching the operation between the first and second electrode groups 21, 24, 31, and 41.

b) keeping the subject 60 in a standing position and having the subject 60 contact the first and second electrode sets 21, 24, 31, 41 of the bioimpedance measuring device 10 with at least two of the limbs, respectively A variety of different ways of using can be derived. For example, the subject 60 may choose to stand on the pedal platform 20 with both feet and contact the first and second electrode groups 21, 24 of the pedal platform 20, or alternatively, hold the left and right handles with both hands. 30, 40 is in contact with the first electrode group 31 of the left handle 30 and the second electrode group 41 of the right handle 40, or may stand behind the pedal platform 20 with both feet, and then hold the left and right handles 30 with both hands. 40. The hands and feet are respectively brought into contact with the first electrode group 31 of the left handle 30, the second electrode group 41 of the right handle 40, and the first and second electrode groups 21, 24 of the pedal platform 20.

c) inputting a measuring current I to one of the first and second electrode groups 21, 24, 31, 41 of the bio-impedance measuring device 10, and measuring the frequency of the current I is between 5 KHz and 200 KHz The measurement current is received between the other of the first and second electrode groups 21, 24, 31, 41 of the bio-impedance measuring device 10. Therefore, the subject 60 can control the actuation between different electrodes by using the switch 50 in accordance with the different usage modes of the foregoing steps, thereby measuring different parts.

In the measurement method of the hand opponent, as shown in FIGS. 3 and 4, the subject 60 holds the left and right handles 30, 40 and the first electrode group 31 of the left handle 30 and the right with both hands in a standing posture. The second electrode group 41 of the handle 40 is in contact, and the measuring current I is controlled by the switch 50 to flow between the first electrode group 31 of the left handle 30 and the second electrode group 41 of the right handle 40, since the current I is measured only By the left and right upper limbs 61, 62 of the subject 60, the resistance values and capacitance values of the left and right upper limbs 61, 62 can be measured.

In the foot-to-foot measurement method, as shown in FIGS. 3 and 5, the subject 60 stands on the pedal platform 20 and contacts the first and second electrode groups 21 and 24 with the feet of the feet, and then The changeover switch 50 controls the measurement current I to flow between the first and second electrode groups 21, 24 of the pedal platform 20, so that the resistance values and capacitance values of the left and right lower limbs 63, 64 can be measured.

In the hand-to-foot measurement method, as shown in FIGS. 3 and 6, the subject 60 only touches the first electrode group 21 of the foot platform 20 with the sole of the right foot, while holding the right handle with only the right hand. 40 is in contact with the second electrode group 41 of the right handle 40, and then the switching current is controlled by the switch 50 to flow between the first electrode group 21 of the foot platform 20 and the second electrode group 41 of the right handle 40. The resistance values and capacitance values of the right upper limb 62, the trunk 65, and the right lower limb 64 were measured. Similarly, as shown in FIGS. 3 and 7, if the subject 60 is changed to contact the second electrode group 24 of the foot platform 20 with the sole of the left foot, the left handle 30 and the left handle 30 are simultaneously held with the left hand. The first electrode group 31 is in contact with each other, and then the switching switch 50 controls the measuring current I at the second electrode group 24 of the pedal platform 20 and The first electrode group 31 of the left handle 30 flows between the first electrode group 31, so that the resistance values and capacitance values of the left upper limb 61, the trunk 65, and the left lower limb 63 can be measured.

In the measurement method of the above limbs, as shown in FIGS. 3 and 8, the subject 60 touches only the second electrode group 24 of the pedal platform 20 with the sole of the left foot, and holds the left and right handles with both hands. 30, 40 is in contact with the first electrode group 31 of the left handle 30 and the second electrode group 41 of the right handle 40, and then the switching current is controlled by the switch 50 to the second electrode group 24 and the left handle 30 of the pedal platform 20. The first electrode group 31 and the second electrode group 41 of the right handle 40 flow between each other, so that the resistance value and the capacitance value of the left upper limb 61 can be measured. Similarly, as shown in FIGS. 3 and 9, if the subject 60 is changed to contact the first electrode group 21 of the pedal platform 20 with the sole of the right foot, the hands remain unchanged, and then the measurement is controlled by the switch 50. The current flows between the first electrode group 21 of the pedal platform 20, the first electrode group 31 of the left handle 30, and the second electrode group 41 of the right handle 40, so that the resistance value and the capacitance value of the right upper limb 62 can be measured. .

In the measurement method of the lower limbs, as shown in FIGS. 3 and 10, the subject 60 stands on the pedal platform 20 and contacts the first and second electrode groups 21 and 24 of the pedal platform 20 with the soles of the feet. And holding the left handle 30 with the left hand only in contact with the first electrode group 31 of the left handle 30, and then controlling the current I on the first and second electrode groups 21, 24 of the pedal platform 20 and the left by the switch 50 The first electrode group 31 of the handle 30 flows between the first electrode group 31, so that the resistance value and the capacitance value of the left lower limb 63 can be measured. Similarly, as shown in FIGS. 3 and 11, if the subject changes to hold the right handle 40 with the right hand and the second electrode group 41 of the right handle 40, the feet remain the first and the second of the pedal platform 20. The two electrode groups 21, 24 are in contact, and the switching current control flow I is controlled by the switch 50 to flow between the first electrode group 21, 24 of the pedal platform 20 and the second electrode group 41 of the right handle 40, so that The resistance value and capacitance value of the right lower limb 64 were measured.

In the measurement of the torso, as shown in Figures 3 and 12, the subject 60 stands on the pedal platform and contacts the first and second electrode sets 21, 24 of the pedal platform 20 with the soles of the feet. Then, the left and right handles 30 and 40 are respectively brought into contact with the first electrode group 31 of the left handle 30 and the second electrode group 41 of the right handle 40, and then the measuring current I is controlled by the switch 50 on the pedal platform. The first electrode of the second electrode group 21, 24, the first electrode group 31 of the left handle 30, and the second electrode group 41 of the right handle flow between the second electrode group 31, so that the resistance value and the capacitance value of the trunk 65 can be measured.

d) After the measurement is completed, the resistance value and the capacitance resistance value of the tested portion are calculated by a program built in the bioimpedance measuring device 10, and a phase angle is obtained for the calculation result by using the electrical impedance spectrum analysis method. The subject 60 can be used as a basis for judging his or her physiological condition based on the analysis result.

On the other hand, since the body of the subject 60 is standing, the distribution of water in the body is affected by gravity and is concentrated in the lower limbs, which may cause errors in the measurement results. Therefore, the resistance value and the capacitance resistance value can be further corrected in the calculation. The subject 60 can obtain a more accurate measurement result, thereby obtaining a corresponding phase angle. The resistance value is calculated by the following formula: R _i ( t ) = C ₁ ( t ) + C ₂ (t) × R , where R _i is the corrected resistance value, and R is the resistance value obtained by the actual measurement. , C ₁ ~ C ₂ is the correction compensation function, t is time, and the capacitance resistance value is calculated by the following formula: ,one of them For the corrected capacitance value, X _c is the capacitance value obtained by the actual measurement, t is time, C ₃ ~ C ₄ is the correction compensation function, and the phase angle is calculated by the following formula: , where R _i is the corrected resistance value, For the corrected capacitance value, t is time and φ _i is the phase angle.

In summary, the conventional technology is a reclining type and only a hand-to-foot mode, and requires the help of others to complete the operation. The measuring method of the present invention is a standing type and has a single hand. The different processes of the foot, the single hand opponent, the single foot to the foot or the integrated multilimb segment can be completed by themselves without the help of others. Therefore, the present invention can increase the measurement aspect compared with the conventional technology. Convenience and practicality.

Claims (9)

A standing bioimpedance measuring method comprising the steps of: a) providing a bioimpedance measuring device having at least a first electrode group and at least a second electrode group; b) allowing a The tester is kept in a standing position, and the subject is contacted with the first and second electrode sets of the bioimpedance measuring device by two of the limbs; c) the first and the first of the bioimpedance measuring devices One of the two electrode sets inputs a measuring current, and the measuring current is received by the other one of the first and second electrode sets of the bioimpedance measuring device; and d) calculating the measured subject The resistance value of the part and the capacitance resistance value, and a phase angle is obtained according to the calculation result; the resistance value is calculated by the following formula: R _i ( t )= C ₁ ( t )+ C ₂ (t)× R , the capacitance resistance value Calculated by the following formula: The phase angle is calculated by the following formula: , where R _i is the corrected resistance value, and R is the resistance value obtained by actual measurement. For the corrected capacitance value, X _c is the capacitance value obtained by the actual measurement, t is time, C ₁ ~ C ₄ is the correction compensation function, and φ _i is the phase angle. The standing bioimpedance measuring method according to claim 1, wherein the hands of the subject touch the first and second electrode groups. The standing bio-impedance measurement method according to claim 1, wherein the two feet of the subject are respectively in contact with the first and second electrode groups of the bio-impedance measuring device. The standing bio-impedance measurement method according to claim 1, wherein one of the subjects touches the first electrode group of the bio-impedance measuring device, and one of the subjects touches the living body A second electrode set of the impedance measuring device. The standing bio-impedance measurement method according to claim 1, wherein the biometric measuring device has two first electrode groups and one second electrode group, one of the subject and one of the feet Each of the first electrode groups is contacted, and the other hand of the subject contacts the second electrode group. The standing bio-impedance measurement method according to claim 1, wherein the biometric measuring device has two first electrode groups and one second electrode group, one of the subject and one of the feet Each of the first electrode groups is contacted, and the other one of the subjects contacts the second electrode group. The standing bio-impedance measurement method according to claim 1, wherein the biometric measuring device has two first electrode groups and two second electrode groups, one of the subject and one of the legs Each of the first electrode groups is contacted, and the other hand of the subject is in contact with the other one of the second electrode groups. The standing bio-impedance measuring method according to claim 1, wherein the measuring current has a frequency between 5 kHz and 200 kHz. A bioimpedance measuring device used in the method of claim 1, comprising: a pedal platform having a first electrode group and a second electrode group; and a pair of handles connected to the pedal platform, One of the handles has a first electrode set, and the other handle has a second electrode set; And a switch for connecting the pedal platform and each of the handles for switching between the first and second electrode groups of the pedal platform and the first and second electrode groups of the pair of handles.