TWI548435B - The construction of incubator for jaundice - Google Patents

Description

Insulation box structure for Huangqi phototherapy

The invention relates to an incubator structure for jaundice phototherapy, in particular to an incubator structure for jaundice phototherapy which has a reflective film on each wall surface of the incubator and enables the reflective film to achieve high reflectivity.

At present, the common neonatal jaundice refers to a group of diseases caused by too high bilirubin in neonates. In severe cases, neonatal nervous system damage may cause bilirubin encephalopathy, affecting neonatal mental development, and studies have shown that Bilirubin can absorb light, accelerate the oxidative decomposition of free bilirubin by light irradiation, promote the removal and excretion of bilirubin, reduce the concentration of unconjugated bilirubin in serum, and prevent the occurrence of nuclear jaundice. Therefore, if the serum bilirubin is higher than 205 μmol/L in term, and the ultra-low birth weight is higher than 85 μmol/L: if the very low birth weight is higher than 103 μmol/L, It is the indication for phototherapy.

Moreover, according to current research, the wavelength of blue LED is the most suitable source for the treatment of neonatal jaundice. In phototherapy, the newborn nude is placed flat in the phototherapy box, and the eyes and the perineum are covered with black cloth. The newborn is then illuminated with single or double light. There are many precautions for phototherapy, including: 1 The time for phototherapy is generally 24 to 48 hours, and should not exceed 3 days. 2 Because blue light can decompose riboflavin in the body, that is, vitamin B2, vitamin B2 should be given to newborns when the duration of light exceeds 24 hours to prevent vitamin B2 deficiency. 3 can not simply rely on the disappearance of jaundice as the basis for stopping phototherapy, but should be based on the decline in serum bilirubin concentration. Because phototherapy mainly acts on the superficial tissues of the skin, the regression of jaundice does not mean that serum bilirubin is normal. 4 phototherapy does not affect breastfeeding, and the newborn can be taken out of the phototherapy box for feeding. In order to facilitate breastfeeding, the phototherapy box can be placed next to the mother's bed, and the medical staff should observe and care regularly. 5 The side effects of phototherapy are relatively small. Children may have fever, diarrhea and rash, but they are not serious and will not affect the treatment. 6 because the newborn is naked In the phototherapy box, the activity space is large, and it is easy to scratch the skin. Therefore, after the phototherapy is finished, the newborn skin should be inspected for damage, so as to be treated in time to prevent secondary infection.

In addition, in the theory of thin film optics, it is necessary to design a lens with high reflectivity, usually using a low refractive index material and a high refractive index material to prepare a pattern of mutually stacked layers, currently having (HL) ^m or (LH) ^m or L (HL) ^m or H (LH) ^m type, and control the film thickness according to the wavelength of the incident light, where L represents a low reflectivity film, H represents a high reflectivity film, and m is the stacking period number.

At present, the mechanism used by newborns who need to take care of the jaundice is to combine the blue LED phototherapy device with the incubator, and the blue LED phototherapy device is usually placed directly or in the upper or side of the incubator for the newborn. The child can receive blue light treatment in a constant temperature incubator. However, although the newborn can avoid temperature loss when irradiating blue light, and has a relatively large area of illumination, the illumination treatment time needs 48 to 72 hours, and the hospital stay time. It takes 2 to 5 days, and when the treatment is very long, it often causes anxiety in the hearts of newborn parents.

In view of this, the present inventors continue to innovate and develop, mainly to improve the long-term illumination time of newborns who need phototherapy, which often causes anxiety problems in the hearts of newborn parents, and then proposes an incubator structure for jaundice phototherapy, and A blue light illumination includes: a box body including an accommodating space, a lying area in the box body, and a reflective film on the inner wall surface of the box body to reflect the blue light to the lying Lying area.

Wherein, the reflective film is represented by an arithmetic expression of a(LH) ^m1 (LH) ^m2 , wherein: a is a film thickness control parameter, and (LH) ^m1 (LH) ^m2 is a first film stack Stacked with a second film stack, the first film stack is of the (LH) ^m1 type, the second film stack is of the (LH) ^m2 type, and the LH is a low refractive index material and a high refractive index material. Stacked on each other, L is a low refractive index material, H is a high refractive index material, m1 is the number of first membrane stack cycles, and m2 is the number of second membrane stack cycles.

Wherein, the film thickness control parameter a is between 0.7732 and 1.6066, and the first film stack cycle number is m1≧2, and the second film stack cycle number is m2≧2.

Wherein, the first membrane stack cycle number is 6≧m1≧2, and the second membrane stack cycle number is 6≧m2≧2.

Wherein, the ratio of the refractive index of the high refractive index material to the refractive index of the low refractive index material is between 1.3125 and 1.7404.

Wherein, the low refractive index material is one of cryolite (Na3AlF6), magnesium fluoride (MgF2) or cerium oxide (SiO2).

Wherein, the high refractive index material is one of titanium dioxide (TiO2), zinc sulfide (ZnS), ceria (CeO2) or zirconium dioxide (ZrO2).

Wherein, the reflective film is coated or vapor-deposited on the inner wall surface of the casing.

Wherein, there is a light source in the box, the blue light is emitted by the light source, and the wavelength of the blue light is between 425 nm and 475 nm.

The effect of the invention is:

1. The invention coats or vapor-deposits a reflective film on the inner wall surface of the box, so that regardless of the shape of the box, or the position of the light source in the box, the blue light emitted by the light source can be effectively Nearly 100% is reflected to newborns lying in the box and having symptoms of jaundice.

2. The invention can effectively improve the efficiency of blue light irradiation, so that the time for the newborn with the symptoms of jaundice to be greatly reduced when irradiating blue light can achieve the effect of reducing the cost.

3. The invention has simple design, but can effectively improve the shortcomings of the newborns who currently have symptoms of jaundice when the blue light is irradiated.

(1) ‧‧‧ cabinet

(11) ‧‧‧ accommodating space

(12)‧‧‧ lying area

(13) ‧‧‧ inner wall

(131)‧‧‧Reflective film

(A) ‧‧‧Light source

(B) ‧‧‧Substrate

(L)‧‧‧Low reflectivity film

(H)‧‧‧High reflectivity film

(a) ‧ ‧ film thickness control parameters

(a ₁ ) ‧ ‧ film thickness control parameters

(a ₂ ) ‧ ‧ film thickness control parameters

[First Figure] is a cross-sectional view showing the structure of the present invention.

[Second figure] is a schematic view of the substrate and the film stack of the present invention. The (LH) ^{2 is taken} as an example, and the high and low refractive index coatings are sequentially stacked on one substrate, and four layers are included.

[FIG. 1] FIG. 1 is a schematic view showing a substrate and a film stack of the present invention. Taking (HL) ² as an example, a low- and high-index coating is sequentially stacked on a substrate, and four layers are included.

[Fourth diagram] is a schematic diagram of the substrate and the film stack of the present invention, illustrating 1.2 (LH) ² (LH) ² as an example, sequentially stacking high and low refractive index coatings on a substrate, and comprising 8 layers. .

[Fifth image] is a reflectance spectrum of the first experiment of the present invention at an incident angle of 0 degrees.

[Sixth image] is a reflectance spectrum diagram of the first experiment of the present invention at an incident angle of 89 degrees.

[Seventh image] is a reflectance spectrum diagram of the second experiment of the present invention at an incident angle of 0 degrees.

[Eighth image] is a reflectance spectrum diagram of the second experiment of the present invention at an incident angle of 89 degrees.

The present invention is an incubator construction for jaundice phototherapy, and the main technical features, objects and effects will be clearly shown in the following embodiments.

First, please refer to the first figure, the present invention comprises a box (1), the box (1) comprises an accommodating space (11), and a lie in the box (1) In the area (12), the lying area (12) comprises a cushion, mainly for a newborn having symptoms of jaundice to comfortably lie therein, and opposite to the lying area (12) There is at least one light source (A). In the embodiment, the light source (A) is disposed above the box (1), and the light source (A) emits a wavelength It is a blue light between 425 nm and 475 nm. It is pointed out by current research that the wavelength of the blue light is most suitable as a light source for the treatment of neonatal jaundice, and the inner wall surface in the box (1). (13) coating or vapor-depositing a reflective film (131), and the reflecting film (131) mainly reflects blue light emitted from the light-emitting source (A) to the lying area (12) to lie A newborn lying in the lying area (12) and having symptoms of jaundice can effectively receive the blue light.

Furthermore, please refer to the second and third figures. First, in the theory of thin film optics, low-refractive-index materials and high-refractive-index materials are usually used to prepare the layers of the film-layer alternately stacked. Currently, there are (HL). ^m or (LH) ^m or L (HL) ^m or H (LH) ^m , and then control a low refractive index coating (L) and a high refractive index coating (H) according to the wavelength of an incident light A film thickness control parameter (a), where m is the number of cycles of the stack. The reflective film of the embodiment of the present invention is represented by an arithmetic expression of a(LH) ^m1 (LH) ^m2 , wherein: a is a film thickness control parameter, and (LH) ^m1 (LH) ^m2 is a first film. The stack is stacked on top of a second stack, the first stack is of the (LH) ^m1 type, the second stack is of the (LH) ^m2 type, and the LH is a low refractive index material and a high refractive index The materials are stacked on each other, wherein L is a low refractive index material and H is a high refractive index material. In the embodiment, the low refractive index material is cryolite (Na3AlF6), magnesium fluoride (MgF2). Or one of cerium oxide (SiO2), and the high refractive index material is one of titanium dioxide (TiO2), zinc sulfide (ZnS), cerium oxide (CeO2) or zirconium dioxide (ZrO2), and m1 For the first stack cycle number, m2 is the number of second stack cycles, the present invention utilizes a substrate (B) during operation and sequentially injects the low reflectivity film (L) with the high reflectance by the above equation. The film (H) is coated or evaporated on the substrate (B), wherein the substrate (B) is made of quartz or glass or plastic, and the low reflectance of the last layer is coated or evaporated. Membrane (L) By high reflectivity film (H) lines in contact with air, which during operation of the expression may be: refractive index of air ^{| a (LH) m1 (LH} ) m2 | refractive index of the substrate, wherein, in (LH) ² Example The substrate (B) is sequentially coated or vapor-deposited with a high reflectance film (H) and a low reflectance film (L), and in order: high reflectance film (H), low reflectance Film (L), high reflectivity film (H), low reflectivity film (L), a total of four layers, and as shown in the second figure; and so on, if (HL) ^{2 is taken} as an example, the substrate (B) sequentially coating or vapor-depositing the low reflectance film (L) and the high reflectance film (H), and sequentially: low reflectance film (L), high reflectance film (H), Low reflectivity film (L), high reflectivity film (H), a total of four layers, and as shown in the third figure, and in the present embodiment, the film thickness control parameter (a) is between 0.7732 and 1.6066 Between the first film stack cycle number m1≧2, the second film stack cycle number m2≧2, and the ratio of the refractive index of the high refractive index material to the refractive index of the low refractive index material is It is between 1.3125 and 1.7407.

Furthermore, referring to the fourth figure, the first film stack is of the (LH) ^m1 type, and in the (LH) ^m1 type, each high reflectance film (H) or low reflectance The film (L) has a film thickness control parameter (a ₁ ), and the film thickness control parameter (a ₁ ) is exemplified by 1; and the second film stack is of the (LH) ^{m 2} type, and In the LH) ^m2 type, each high reflectance film (H) or low reflectance film (L) has a film thickness control parameter (a ₂ ), and the film thickness control parameter (a ₂ ) is 1.2, According to the above, in the present embodiment, the calculation formula of 1.2 (LH) ² (LH) ² is taken as an example. First, the substrate (B) is sequentially coated or vapor-deposited with a high reflectance film (H). a low reflectance film (L), a high reflectance film (H), a low reflectance film (L), and the film thickness control parameter (a ₁ ) is 1, after a total of four layers, further using a film thickness The control parameter (a ₂ ) is 1.2, and the low-reflectivity film (L) is successively coated or vapor-deposited onto the high-reflectance film (H), the low-reflectance film (L), and the high-reflectance film. (H), low reflectivity film (L), a total of four layers, and finally contains eight layers, and the four layers on the substrate (B), that is, the film thickness control of the first film stack The parameter (a ₁ ) is 1, while the other four layers, that is, the film thickness control parameter (a ₂ ) of the second film stack is 1.2.

Furthermore, referring to the fifth and sixth figures, for the blue light wavelength between 425 nm and 475 nm, in the simulation experiment, the low refractive index material is selected as magnesium fluoride. (MgF2), its refractive index is n _L = 1.38, and the high refractive index material is titanium dioxide (TiO2), its refractive index is n _H = 2.35, and a central wavelength λo = 460 nm is designed, and the film type is (LH) ^m , and the above-mentioned operational simulation experiment, in which the refractive index of air is 1, and the refractive index of the quartz substrate is 1.46, while the long wavelength region of the film is 1.2 (LH) from the film stack near the air end. The ^6- state is controlled, and the short-wavelength region is controlled by the (LH) ⁶ type of the film stack close to the quartz substrate. Further, the blue light emitted by the aforementioned light source (A) [as shown in the first figure] is incident angle. The reflectance spectrum at =0 degrees is shown in the fifth figure, and the reflectance in the range of 425 nm to 475 nm in the whole region is on average 99%; and in the aforementioned light source (A) [as shown in the first figure) The reflectance spectrum of the emitted blue light at an incident angle = 89 degrees is shown in the sixth figure, and the reflection in the whole region is in the range of 425 nm to 475 nm. The average rate is also as high as 99.4%~100%, and the high reflectivity covers the requirement that the illuminating angle of the astigmatic LED is about 75 degrees, and it can be seen from the above that the present invention can effectively achieve the effect of high reflectivity.

Furthermore, referring to the seventh and eighth figures, in the embodiment, the high refractive index material is germanium (Ge), the refractive index n _H = 4.1, and the low refractive index material is fluorine. Magnesium (MgF2), its refractive index is n _L = 1.38, and after experimental simulation test, adjust the parameters a, m1, m2 of the formula, and know that the number of layers is only 8 layers, and the above-mentioned light source (A) [As shown in the first figure] The reflectance spectrum of the blue light emitted at an incident angle of 0 to 89 degrees is shown in the seventh and eighth figures. The figure shows that the whole area is 425 nm to 475. The reflectance in the nanometer range is as high as 99.9% on average to fully achieve high reflectivity.

It should be further noted that, when performing experimental simulation, the incident angle of the blue light emitted by the light source (A) [as shown in the first figure] is 0 to 89 degrees, and when the refractive index and low refractive index of the high refractive index material are The ratio of the refractive index of the rate material is 0.7404, a is 1.2, m1 is 6, and when m2 is 6, the film stack is 24 layers; and when the ratio of the refractive index of the high refractive index material to the refractive index of the low refractive index material The system is 2.971, a is 1.2, m1 is 2, and when m2 is 2, the film stack is 8 layers, and both can achieve the spectral requirements of nearly 100% high reflectance of blue light. From the above, when high refractive index material is known The higher the ratio of the refractive index to the refractive index of the low refractive index material, the less the number of layers required for the film stack.

In view of the foregoing description of the embodiments, the operation and the use of the present invention and the effects of the present invention are fully understood, but the above described embodiments are merely preferred embodiments of the present invention, and the invention may not be limited thereto. Included within the scope of the present invention are the scope of the present invention.

(1) ‧‧‧ cabinet

(11) ‧‧‧ accommodating space

(12)‧‧‧ lying area

(13) ‧‧‧ inner wall

(131)‧‧‧Reflective film

(A) ‧‧‧Light source

Claims (7)

The invention relates to an incubator structure for jaundice phototherapy, which is used for illuminating a blue light, and comprises: a box body, an accommodating space, a lying area in the box body, and a lie on the inner wall surface of the box body a reflective film reflects the blue light to the lying area; the reflective film is represented by an arithmetic expression of a(LH) ^m1 (LH) ^m2 , wherein: a is a film thickness control parameter, (LH ^M1 (LH) ^m2 is a first film stack and a second film stack stacked on each other, the first film stack is (LH) ^m1 type, and the second film stack is (LH) ^m2 type LH is a low refractive index material and a high refractive index material stacked on each other, L is a low refractive index material, H is a high refractive index material, m1 is the number of first film stack cycles, and m2 is the number of second film stack cycles; The thickness control parameter a is between 0.7732 and 1.6066, and the first membrane stack number is m1≧2, and the second membrane stack number is m2≧2. The incubator structure for jaundice phototherapy according to claim 1, wherein the first film stack cycle number is 6 ≧ m1 and the second film stack cycle number is 6 ≧ m 2 . The incubator structure for xanthine phototherapy according to claim 1, wherein a ratio of a refractive index of the high refractive index material to a refractive index of the low refractive index material is between 1.3125 and 1.7404. The incubator structure for jaundice phototherapy according to claim 1, wherein the low refractive index material is one of cryolite (Na3AlF6), magnesium fluoride (MgF2) or cerium oxide (SiO2). . The incubator structure for jaundice phototherapy according to claim 1, wherein the high refractive index material is titanium dioxide (TiO2), zinc sulfide (ZnS), ceria (CeO2) or zirconium dioxide ( One of ZrO2). The incubator structure for jaundice phototherapy according to claim 1, wherein the reflective film is coated or vapor-deposited on the inner wall surface of the casing. The incubator structure for jaundice phototherapy according to claim 1, wherein the box body has a light source, the blue light is emitted by the light source, and the wavelength of the blue light is between 425 nm and 475 nm. Between meters.