TWI367761B - Pharmaceutical composition containing hardly water soluble pharmaceutical substance - Google Patents

Pharmaceutical composition containing hardly water soluble pharmaceutical substance

Info

Publication number: TWI367761B
Authority: TW; Taiwan
Prior art keywords: composition containing; water soluble; hardly water; pharmaceutical composition; containing hardly
Prior art date: 2005-03-14

Application number

TW095108368A

Other languages

English (en)

Other versions

TW200714293A (en

Inventor

Koichi Takeda

Kenji Matsuda

Toshimitsu Terao

Tadaaki Inoue

Takashi Imagawa

Original Assignee

Otsuka Pharma Co Ltd

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2005-03-14

Filing date

2006-03-13

Publication date

2012-07-11

2006-03-13 Application filed by Otsuka Pharma Co Ltd filed Critical Otsuka Pharma Co Ltd

2007-04-16 Publication of TW200714293A publication Critical patent/TW200714293A/zh

2012-07-11 Application granted granted Critical

2012-07-11 Publication of TWI367761B publication Critical patent/TWI367761B/zh

Classifications

- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
- A61K47/12—Carboxylic acids; Salts or anhydrides thereof
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
- A61K31/337—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having four-membered rings, e.g. taxol
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/10—Dispersions; Emulsions
- A61K9/107—Emulsions ; Emulsion preconcentrates; Micelles
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/10—Dispersions; Emulsions
- A61K9/107—Emulsions ; Emulsion preconcentrates; Micelles
- A61K9/1075—Microemulsions or submicron emulsions; Preconcentrates or solids thereof; Micelles, e.g. made of phospholipids or block copolymers
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/10—Dispersions; Emulsions
- A61K9/127—Synthetic bilayered vehicles, e.g. liposomes or liposomes with cholesterol as the only non-phosphatidyl surfactant
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents

Landscapes

Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Medicinal Chemistry (AREA)
Pharmacology & Pharmacy (AREA)
Animal Behavior & Ethology (AREA)
General Health & Medical Sciences (AREA)
Public Health (AREA)
Veterinary Medicine (AREA)
Epidemiology (AREA)
Dispersion Chemistry (AREA)
Biophysics (AREA)
Molecular Biology (AREA)
Dermatology (AREA)
Chemical Kinetics & Catalysis (AREA)
General Chemical & Material Sciences (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Organic Chemistry (AREA)
Engineering & Computer Science (AREA)
Oil, Petroleum & Natural Gas (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Medicinal Preparation (AREA)

TW095108368A 2005-03-14 2006-03-13 Pharmaceutical composition containing hardly water soluble pharmaceutical substance TWI367761B (en)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
JP2005071640		2005-03-14

Publications (2)

Publication Number	Publication Date
TW200714293A TW200714293A (en)	2007-04-16
TWI367761B true TWI367761B (en)	2012-07-11

Family

ID=36991586

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
TW095108368A TWI367761B (en)	2005-03-14	2006-03-13	Pharmaceutical composition containing hardly water soluble pharmaceutical substance

Country Status (8)

Country	Link
US (1)	US20080128314A1 (zh)
EP (1)	EP1862183B1 (zh)
JP (1)	JP4929158B2 (zh)
KR (1)	KR101391020B1 (zh)
CN (1)	CN101137395B (zh)
DE (1)	DE602006017979D1 (zh)
TW (1)	TWI367761B (zh)
WO (1)	WO2006098241A1 (zh)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
SI1931321T1 (sl) *	2005-08-31	2019-07-31	Abraxis Bioscience, Llc	Sestave, ki zajemajo slabo vodotopne farmacevtske učinkovine in antimikrobna sredstva
BRPI0615292A8 (pt)	2005-08-31	2018-03-06	Abraxis Bioscience Llc	composições e métodos para preparação de fármacos de má solubilidade em água com estabilidade aumentada
KR100917809B1 (ko) *	2006-05-22	2009-09-18	에스케이케미칼주식회사	우수한 저장안정성을 갖는 도세탁셀 함유 주사제 조성물
EP2025333A1 (en) *	2007-08-14	2009-02-18	Pharmatex Italia Srl	Injectable pharmaceutical formulation of taxoids
US20090286832A1 (en) *	2008-05-15	2009-11-19	Kiichiro Nabeta	Narcotic emulsion formulations for treatment of surgical pain
CN101612120B (zh) *	2008-12-16	2011-02-02	海南美大制药有限公司	氟罗沙星冻干乳剂及其生产方法
WO2010098897A1 (en) *	2009-02-26	2010-09-02	Teikoku Pharma Usa, Inc.	Narcotic emulsion formulations for treatment of cancer pain
CN102038635A (zh) *	2009-10-23	2011-05-04	天津天士力集团有限公司	一种含有pH值调节剂的紫杉烷类药物溶液及其制备方法
WO2012094020A1 (en) *	2010-01-07	2012-07-12	Innopharma, Inc.	Methods and compositions for delivery of taxanes in stable oil-in-water emulsions
CN101926757B (zh) *	2010-09-01	2013-01-02	北京大学	一种难溶性药物的液体组合物及其制备方法
TWI511725B (zh) *	2010-11-10	2015-12-11	Tasly Holding Group Co Ltd	A taxane-containing drug solution containing chelating agent and a preparation method thereof
CN102579338B (zh) *	2012-03-02	2013-06-19	首都医科大学	一种紫杉醇静脉注射脂肪乳的制备及应用
CN104886357B (zh) *	2014-09-15	2018-09-07	浙江万方生物科技有限公司	一种用于畜禽的水溶性肉桂醛添加剂的制备方法

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
WO1989002265A1 (fr) *	1987-09-07	1989-03-23	Teijin Limited	Emulsion grasse contenant un medicament, du type prepare immediatement avant l'utilisation, et procede de preparation d'une telle emulsion grasse contenant un medicament
US5616330A (en) *	1994-07-19	1997-04-01	Hemagen/Pfc	Stable oil-in-water emulsions incorporating a taxine (taxol) and method of making same
KR19990075621A (ko) *	1998-03-23	1999-10-15	임성주	경사 평판형 배양조
CA2366723C (en) *	1999-03-09	2011-08-02	Protarga, Inc.	Fatty acid-anticancer conjugates and uses thereof
EP1185301A1 (en) *	1999-05-24	2002-03-13	Sonus Pharmaceuticals, Inc.	Emulsion vehicle for poorly soluble drugs
EP1303261B1 (en) *	2000-07-24	2005-03-09	Pharmacia & Upjohn Company	Self-emulsifying drug delivery systems for extremely water-insoluble, lipophilic drugs
KR20020013174A (ko) *	2000-08-11	2002-02-20	민경윤	경구 흡수율이 낮은 약물의 흡수율을 증가시키기 위한경구용 조성물
JP2004524368A (ja) *	2001-03-27	2004-08-12	フェアーズファーマシューティカルリサーチエヌ．ヴェー．	低い水溶性を有する生物学的に活性な化合物を可溶化するための方法および組成物
US20040241094A1 (en) *	2001-09-13	2004-12-02	Hesson Chung	Oily paclitaxel composition and formulation for chemoembolization and preparation method thereof

2006
- 2006-03-10 JP JP2007508109A patent/JP4929158B2/ja not_active Expired - Fee Related
- 2006-03-10 WO PCT/JP2006/304753 patent/WO2006098241A1/ja not_active Ceased
- 2006-03-10 CN CN2006800073453A patent/CN101137395B/zh not_active Expired - Fee Related
- 2006-03-10 US US11/885,969 patent/US20080128314A1/en not_active Abandoned
- 2006-03-10 KR KR1020077019845A patent/KR101391020B1/ko not_active Expired - Fee Related
- 2006-03-10 DE DE602006017979T patent/DE602006017979D1/de active Active
- 2006-03-10 EP EP06715523A patent/EP1862183B1/en not_active Ceased
- 2006-03-13 TW TW095108368A patent/TWI367761B/zh not_active IP Right Cessation

Also Published As

Publication number	Publication date
EP1862183B1 (en)	2010-11-03
CN101137395A (zh)	2008-03-05
JPWO2006098241A1 (ja)	2008-08-21
KR20080002752A (ko)	2008-01-04
DE602006017979D1 (de)	2010-12-16
JP4929158B2 (ja)	2012-05-09
CN101137395B (zh)	2012-10-31
US20080128314A1 (en)	2008-06-05
EP1862183A1 (en)	2007-12-05
EP1862183A4 (en)	2009-12-30
KR101391020B1 (ko)	2014-04-30
TW200714293A (en)	2007-04-16
WO2006098241A1 (ja)	2006-09-21

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SI1962873T1 (sl)	2013-10-30	Farmacevtski sestavki, ki vsebujejo bakterijo za zmanjĹˇanje oksalata
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SI1909761T1 (sl)	2017-07-31	Farmacevtski sestavek, ki obsega granuliran pantoprazol
EP1845944A4 (en)	2011-07-27	PHARMACEUTICAL COMPOSITIONS
ZA200805355B (en)	2009-04-29	Pharmaceutical compositions containing protein NMA0939
ZA200803566B (en)	2009-10-28	Pharmaceutical compositions
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Legal Events

Date	Code	Title	Description
2018-04-11	MM4A	Annulment or lapse of patent due to non-payment of fees