TW350842B - Novel process for the preparation of form I ranitidine hydrochloride - Google Patents
Novel process for the preparation of form I ranitidine hydrochlorideInfo
- Publication number
- TW350842B TW350842B TW086103469A TW86103469A TW350842B TW 350842 B TW350842 B TW 350842B TW 086103469 A TW086103469 A TW 086103469A TW 86103469 A TW86103469 A TW 86103469A TW 350842 B TW350842 B TW 350842B
- Authority
- TW
- Taiwan
- Prior art keywords
- preparation
- novel process
- ranitidine hydrochloride
- ranitidine
- hydrochloride
- Prior art date
Links
- 238000000034 method Methods 0.000 title abstract 2
- 238000002360 preparation method Methods 0.000 title abstract 2
- 229960001520 ranitidine hydrochloride Drugs 0.000 title abstract 2
- GGWBHVILAJZWKJ-KJEVSKRMSA-N ranitidine hydrochloride Chemical compound [H+].[Cl-].[O-][N+](=O)\C=C(/NC)NCCSCC1=CC=C(CN(C)C)O1 GGWBHVILAJZWKJ-KJEVSKRMSA-N 0.000 title abstract 2
- 238000002425 crystallisation Methods 0.000 abstract 1
- 230000008025 crystallization Effects 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
- C07D307/02—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings
- C07D307/34—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
- C07D307/38—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with substituted hydrocarbon radicals attached to ring carbon atoms
- C07D307/52—Radicals substituted by nitrogen atoms not forming part of a nitro radical
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Abstract
A novel process for the preparation of form 1 ranitidine hydrochloride, by crystallization from at least one C1-C6 alkanol.
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US62082296A | 1996-03-25 | 1996-03-25 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| TW350842B true TW350842B (en) | 1999-01-21 |
Family
ID=24487544
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| TW086103469A TW350842B (en) | 1996-03-25 | 1997-03-19 | Novel process for the preparation of form I ranitidine hydrochloride |
Country Status (3)
| Country | Link |
|---|---|
| AU (1) | AU1972097A (en) |
| TW (1) | TW350842B (en) |
| WO (1) | WO1997035853A1 (en) |
Families Citing this family (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO1999065890A1 (en) * | 1998-06-17 | 1999-12-23 | Russinsky Limited | Ranitidine adduct |
| CN106432147B (en) * | 2015-05-26 | 2018-04-17 | 烟台市华文欣欣医药科技有限公司 | A kind of method for the medicine ranitidine hydrochloride compound for preparing treatment stomach trouble |
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB1565966A (en) * | 1976-08-04 | 1980-04-23 | Allen & Hanburys Ltd | Aminoalkyl furan derivatives |
| IL63968A (en) * | 1980-10-01 | 1985-10-31 | Glaxo Group Ltd | Form 2 ranitidine hydrochloride,its preparation and pharmaceutical compositions containing it |
| CA2120874E (en) * | 1994-04-08 | 2002-01-08 | Keshava Murthy | Form of form 1 ranitidine |
| DE69504156T2 (en) * | 1994-06-24 | 1998-12-24 | Ranbaxy Laboratories, Ltd., New Delhi | Process for the production of ranitidine hydrochloride in crystal form 1 |
-
1997
- 1997-02-25 WO PCT/US1997/002867 patent/WO1997035853A1/en not_active Ceased
- 1997-02-25 AU AU19720/97A patent/AU1972097A/en not_active Abandoned
- 1997-03-19 TW TW086103469A patent/TW350842B/en active
Also Published As
| Publication number | Publication date |
|---|---|
| WO1997035853A1 (en) | 1997-10-02 |
| AU1972097A (en) | 1997-10-17 |
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