TW200720284A - Method for producing radioactive halogen labeled organic compound - Google Patents
Method for producing radioactive halogen labeled organic compoundInfo
- Publication number
- TW200720284A TW200720284A TW095116383A TW95116383A TW200720284A TW 200720284 A TW200720284 A TW 200720284A TW 095116383 A TW095116383 A TW 095116383A TW 95116383 A TW95116383 A TW 95116383A TW 200720284 A TW200720284 A TW 200720284A
- Authority
- TW
- Taiwan
- Prior art keywords
- radioactive halogen
- compound
- organic compound
- labeled organic
- radioactive
- Prior art date
Links
- 230000002285 radioactive effect Effects 0.000 title abstract 5
- 229910052736 halogen Inorganic materials 0.000 title abstract 4
- 150000002367 halogens Chemical class 0.000 title abstract 4
- 238000004519 manufacturing process Methods 0.000 title abstract 3
- 150000002894 organic compounds Chemical class 0.000 title 1
- 150000001875 compounds Chemical class 0.000 abstract 3
- XYFCBTPGUUZFHI-UHFFFAOYSA-N Phosphine Chemical compound P XYFCBTPGUUZFHI-UHFFFAOYSA-N 0.000 abstract 2
- 150000001412 amines Chemical class 0.000 abstract 2
- 150000001491 aromatic compounds Chemical class 0.000 abstract 2
- LFQSCWFLJHTTHZ-UHFFFAOYSA-N Ethanol Chemical compound CCO LFQSCWFLJHTTHZ-UHFFFAOYSA-N 0.000 abstract 1
- 230000002378 acidificating effect Effects 0.000 abstract 1
- 125000002947 alkylene group Chemical group 0.000 abstract 1
- 125000004435 hydrogen atom Chemical group [H]* 0.000 abstract 1
- 125000002887 hydroxy group Chemical group [H]O* 0.000 abstract 1
- 238000002372 labelling Methods 0.000 abstract 1
- 238000000034 method Methods 0.000 abstract 1
- 150000003003 phosphines Chemical class 0.000 abstract 1
- 229910000073 phosphorus hydride Inorganic materials 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
- C07F9/02—Phosphorus compounds
- C07F9/28—Phosphorus compounds with one or more P—C bonds
- C07F9/54—Quaternary phosphonium compounds
- C07F9/5456—Arylalkanephosphonium compounds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K51/00—Preparations containing radioactive substances for use in therapy or testing in vivo
- A61K51/02—Preparations containing radioactive substances for use in therapy or testing in vivo characterised by the carrier, i.e. characterised by the agent or material covalently linked or complexing the radioactive nucleus
- A61K51/04—Organic compounds
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07B—GENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
- C07B59/00—Introduction of isotopes of elements into organic compounds ; Labelled organic compounds per se
- C07B59/001—Acyclic or carbocyclic compounds
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C29/00—Preparation of compounds having hydroxy or O-metal groups bound to a carbon atom not belonging to a six-membered aromatic ring
- C07C29/132—Preparation of compounds having hydroxy or O-metal groups bound to a carbon atom not belonging to a six-membered aromatic ring by reduction of an oxygen containing functional group
- C07C29/136—Preparation of compounds having hydroxy or O-metal groups bound to a carbon atom not belonging to a six-membered aromatic ring by reduction of an oxygen containing functional group of >C=O containing groups, e.g. —COOH
- C07C29/14—Preparation of compounds having hydroxy or O-metal groups bound to a carbon atom not belonging to a six-membered aromatic ring by reduction of an oxygen containing functional group of >C=O containing groups, e.g. —COOH of a —CHO group
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07B—GENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
- C07B2200/00—Indexing scheme relating to specific properties of organic compounds
- C07B2200/05—Isotopically modified compounds, e.g. labelled
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Physics & Mathematics (AREA)
- Epidemiology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Biochemistry (AREA)
- Medicinal Chemistry (AREA)
- Optics & Photonics (AREA)
- Pharmacology & Pharmacy (AREA)
- Molecular Biology (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Nuclear Medicine (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2005136976A JP2006315958A (ja) | 2005-05-10 | 2005-05-10 | 放射性ハロゲン標識有機化合物の製造方法 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| TW200720284A true TW200720284A (en) | 2007-06-01 |
Family
ID=37396543
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| TW095116383A TW200720284A (en) | 2005-05-10 | 2006-05-09 | Method for producing radioactive halogen labeled organic compound |
Country Status (3)
| Country | Link |
|---|---|
| JP (1) | JP2006315958A (zh) |
| TW (1) | TW200720284A (zh) |
| WO (1) | WO2006121035A1 (zh) |
Families Citing this family (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN102471177A (zh) | 2009-07-10 | 2012-05-23 | 拜耳医药股份有限公司 | 低至中压液相色谱在放射性示踪剂纯化中的应用 |
| CN102898470B (zh) * | 2012-11-02 | 2014-12-10 | 北京师范大学 | 一类新型有机膦化合物及其制备方法和应用 |
| JP6555719B2 (ja) * | 2014-11-05 | 2019-08-07 | 国立大学法人東北大学 | ホスホニウム化合物およびその製造方法 |
Family Cites Families (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US7112318B2 (en) * | 2002-02-06 | 2006-09-26 | The Johns Hopkins University | Non-invasive diagnostic imaging technology for mitochondria dysfunction using radiolabeled lipophilic salts |
-
2005
- 2005-05-10 JP JP2005136976A patent/JP2006315958A/ja active Pending
-
2006
- 2006-05-09 WO PCT/JP2006/309303 patent/WO2006121035A1/ja not_active Ceased
- 2006-05-09 TW TW095116383A patent/TW200720284A/zh unknown
Also Published As
| Publication number | Publication date |
|---|---|
| WO2006121035A1 (ja) | 2006-11-16 |
| JP2006315958A (ja) | 2006-11-24 |
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