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TW200720273A - Pharmaceutically active spiro-benzimidazoles - Google Patents

Pharmaceutically active spiro-benzimidazoles

Info

Publication number
TW200720273A
TW200720273A TW095120998A TW95120998A TW200720273A TW 200720273 A TW200720273 A TW 200720273A TW 095120998 A TW095120998 A TW 095120998A TW 95120998 A TW95120998 A TW 95120998A TW 200720273 A TW200720273 A TW 200720273A
Authority
TW
Taiwan
Prior art keywords
benzimidazoles
pharmaceutically active
active spiro
spiro
compounds
Prior art date
Application number
TW095120998A
Other languages
English (en)
Inventor
Peter Jan Zimmermann
Jorg Senn-Bilfinger
Christof Brehm
Wilm Buhr
Maria Vittoria Chiesa
Wolfgang Kromer
Original Assignee
Altana Pharma Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Altana Pharma Ag filed Critical Altana Pharma Ag
Publication of TW200720273A publication Critical patent/TW200720273A/zh

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D471/00Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/10Spiro-condensed systems
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/438The ring being spiro-condensed with carbocyclic or heterocyclic ring systems
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
TW095120998A 2005-06-16 2006-06-13 Pharmaceutically active spiro-benzimidazoles TW200720273A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
EP05105330 2005-06-16

Publications (1)

Publication Number Publication Date
TW200720273A true TW200720273A (en) 2007-06-01

Family

ID=35276210

Family Applications (1)

Application Number Title Priority Date Filing Date
TW095120998A TW200720273A (en) 2005-06-16 2006-06-13 Pharmaceutically active spiro-benzimidazoles

Country Status (16)

Country Link
US (1) US20090093473A1 (zh)
EP (1) EP1899338A1 (zh)
JP (1) JP2008543808A (zh)
KR (1) KR20080020675A (zh)
CN (1) CN101193890A (zh)
AR (1) AR057061A1 (zh)
AU (1) AU2006259123A1 (zh)
BR (1) BRPI0612010A2 (zh)
CA (1) CA2627589A1 (zh)
EA (1) EA200702584A1 (zh)
IL (1) IL188011A0 (zh)
MX (1) MX2007015088A (zh)
NO (1) NO20080144L (zh)
TW (1) TW200720273A (zh)
WO (1) WO2006134111A1 (zh)
ZA (1) ZA200709852B (zh)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DK1961735T3 (da) * 2007-02-22 2010-03-29 Indena Spa Fremgangsmåde til fremstilling af (2R,3S)-3-phenylisoserinmethylesteracetatsalt
WO2008151927A2 (en) * 2007-06-15 2008-12-18 Nycomed Gmbh 6-n-substituted benz imidazole derivatives as acid pump antagonists
MX2012000275A (es) 2009-07-09 2012-02-08 Raqualia Pharma Inc Antagonista de bomba de acido para el tratamiento de enfermedades involucradas en la motilidad gastrointestinal anormal.
SG10202100916PA (en) 2015-02-02 2021-02-25 Valo Early Discovery Inc 3-aryl-4-amido-bicyclic [4,5,0] hydroxamic acids as hdac inhibitors
WO2016126726A1 (en) 2015-02-02 2016-08-11 Forma Therapeutics, Inc. Bicyclic [4,6,0] hydroxamic acids as hdac6 inhibitors
WO2017218950A1 (en) 2016-06-17 2017-12-21 Forma Therapeutics, Inc. 2-spiro-5- and 6-hydroxamic acid indanes as hdac inhibitors

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SE8604566D0 (sv) * 1986-10-27 1986-10-27 Haessle Ab Novel compunds
AR043063A1 (es) * 2002-12-13 2005-07-13 Altana Pharma Ag Bencimidazoles 6-sustituidos y su uso como inhibidores de secreciones gastricas
RS20050730A (sr) * 2003-04-04 2007-11-15 Altana Pharma Ag., Ciklični benzimidazoli
US20040204453A1 (en) * 2003-04-14 2004-10-14 Pfizer Inc 4-Phenyl-piperidine compounds and their use as modulators of opioid receptors

Also Published As

Publication number Publication date
CA2627589A1 (en) 2006-12-21
IL188011A0 (en) 2008-03-20
MX2007015088A (es) 2008-01-24
AU2006259123A1 (en) 2006-12-21
KR20080020675A (ko) 2008-03-05
EP1899338A1 (en) 2008-03-19
WO2006134111A1 (en) 2006-12-21
BRPI0612010A2 (pt) 2010-10-13
JP2008543808A (ja) 2008-12-04
NO20080144L (no) 2008-01-14
AR057061A1 (es) 2007-11-14
ZA200709852B (en) 2008-10-29
AU2006259123A8 (en) 2008-04-03
CN101193890A (zh) 2008-06-04
EA200702584A1 (ru) 2008-06-30
US20090093473A1 (en) 2009-04-09

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