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TW200716555A - Tetrahydronaphthalene derivatives, process for their production and their use as anti-inflammatory agents - Google Patents

Tetrahydronaphthalene derivatives, process for their production and their use as anti-inflammatory agents

Info

Publication number
TW200716555A
TW200716555A TW095113519A TW95113519A TW200716555A TW 200716555 A TW200716555 A TW 200716555A TW 095113519 A TW095113519 A TW 095113519A TW 95113519 A TW95113519 A TW 95113519A TW 200716555 A TW200716555 A TW 200716555A
Authority
TW
Taiwan
Prior art keywords
production
inflammatory agents
tetrahydronaphthalene derivatives
tetrahydronaphthalene
derivatives
Prior art date
Application number
TW095113519A
Other languages
Chinese (zh)
Inventor
Stefan Baurle
Heike Schacke
Markus Berger
Anne Mengel
Original Assignee
Schering Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Schering Ag filed Critical Schering Ag
Publication of TW200716555A publication Critical patent/TW200716555A/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
    • C07D215/02—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
    • C07D215/16—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D215/38—Nitrogen atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/06—Antiasthmatics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C43/00—Ethers; Compounds having groups, groups or groups
    • C07C43/02—Ethers
    • C07C43/20—Ethers having an ether-oxygen atom bound to a carbon atom of a six-membered aromatic ring
    • C07C43/23—Ethers having an ether-oxygen atom bound to a carbon atom of a six-membered aromatic ring containing hydroxy or O-metal groups
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D237/00—Heterocyclic compounds containing 1,2-diazine or hydrogenated 1,2-diazine rings
    • C07D237/26—Heterocyclic compounds containing 1,2-diazine or hydrogenated 1,2-diazine rings condensed with carbocyclic rings or ring systems
    • C07D237/30—Phthalazines
    • C07D237/34—Phthalazines with nitrogen atoms directly attached to carbon atoms of the nitrogen-containing ring, e.g. hydrazine radicals
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
    • C07D239/70—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings condensed with carbocyclic rings or ring systems
    • C07D239/72—Quinazolines; Hydrogenated quinazolines

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Pulmonology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)

Abstract

The invention relates to polysubstituted tetrahydronaphthalene derivatives of formula (I), process for their production and their use as anti-inflammatory agents.
TW095113519A 2005-04-14 2006-04-14 Tetrahydronaphthalene derivatives, process for their production and their use as anti-inflammatory agents TW200716555A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE102005017286A DE102005017286B3 (en) 2005-04-14 2005-04-14 Tetrahydronaphthalene derivatives, process for their preparation and their use as anti-inflammatory agents

Publications (1)

Publication Number Publication Date
TW200716555A true TW200716555A (en) 2007-05-01

Family

ID=36955993

Family Applications (1)

Application Number Title Priority Date Filing Date
TW095113519A TW200716555A (en) 2005-04-14 2006-04-14 Tetrahydronaphthalene derivatives, process for their production and their use as anti-inflammatory agents

Country Status (8)

Country Link
AR (1) AR056314A1 (en)
DE (1) DE102005017286B3 (en)
GT (1) GT200600153A (en)
PA (1) PA8668901A1 (en)
PE (1) PE20061313A1 (en)
TW (1) TW200716555A (en)
UY (1) UY29481A1 (en)
WO (1) WO2006108714A2 (en)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7638515B2 (en) 2003-10-08 2009-12-29 Bayer Schering Pharma Aktiengesellschaft Tetrahydronaphthalene derivatives, process for their production and their use as anti-inflammatory agents
US7662821B2 (en) 2003-10-08 2010-02-16 Bayer Schering Pharma Ag Tetrahydronaphthalene derivatives, process for their production and their use as anti-inflammatory agents
DE502004002403D1 (en) 2003-10-08 2007-02-01 Schering Ag TETRAHYDRONAPHTHALIN DERIVATIVES, METHOD FOR THE PRODUCTION THEREOF AND THEIR USE AS AN INFLAMMATORY INHIBITION
US20080153859A1 (en) 2004-04-05 2008-06-26 Hartmut Rehwinkel Multiply-substituted tetrahydronaphthalene derivatives, process for their production and their use as anti-inflammatory agents
EP1834948A1 (en) 2006-03-15 2007-09-19 Bayer Schering Pharma Aktiengesellschaft Tetrahydronaphtalene derivatives, methods for the production thereof, and their use as antiinflammatory drugs
EP1917963A1 (en) * 2006-10-31 2008-05-07 Bayer Schering Pharma Aktiengesellschaft Cyclic phenyl-substituted indazols, a process for their production and their use as anti-inflammatory agents

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH03289659A (en) * 1990-03-28 1991-12-19 Toshiba Corp Photosensitive composition
AU7176098A (en) * 1997-05-05 1998-11-27 First Chemical Corporation Biradical photoinitiators
DE10038639A1 (en) * 2000-07-28 2002-02-21 Schering Ag New and known N-aryl 2-hydroxy-omega-arylalkanamide derivatives, useful e.g. for treating inflammatory diseases such as rheumatism
AU8022901A (en) * 2000-08-21 2002-03-04 Pacific Corp Novel thiourea derivatives and the pharmaceutical compositions containing the same
PL210288B1 (en) * 2002-05-08 2011-12-30 Bayer Healthcare Ag Hydroxy tetrahydro-naphthalenylurea derivatives
ATE533743T1 (en) * 2002-05-17 2011-12-15 Janssen Pharmaceutica Nv UREA DERIVATIVES OF AMINOTETRALIN AS MODULATORS OF THE VANILLOID RECEPTOR VR1
MXPA04011815A (en) * 2002-06-04 2005-03-31 Galderma Res & Dev Ligands that are inhibitors of the rar receptors.
DE502004002403D1 (en) * 2003-10-08 2007-02-01 Schering Ag TETRAHYDRONAPHTHALIN DERIVATIVES, METHOD FOR THE PRODUCTION THEREOF AND THEIR USE AS AN INFLAMMATORY INHIBITION

Also Published As

Publication number Publication date
UY29481A1 (en) 2006-10-31
PA8668901A1 (en) 2007-01-17
AR056314A1 (en) 2007-10-03
WO2006108714A3 (en) 2007-01-04
GT200600153A (en) 2007-03-19
WO2006108714A2 (en) 2006-10-19
DE102005017286B3 (en) 2006-12-28
PE20061313A1 (en) 2006-12-20

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