TW200610763A - Quaternary alkaloid derivatives - Google Patents
Quaternary alkaloid derivativesInfo
- Publication number
- TW200610763A TW200610763A TW094132316A TW94132316A TW200610763A TW 200610763 A TW200610763 A TW 200610763A TW 094132316 A TW094132316 A TW 094132316A TW 94132316 A TW94132316 A TW 94132316A TW 200610763 A TW200610763 A TW 200610763A
- Authority
- TW
- Taiwan
- Prior art keywords
- reaction products
- water
- treatment
- reaction mixture
- derivatizing agent
- Prior art date
Links
- 150000003797 alkaloid derivatives Chemical group 0.000 title abstract 3
- 239000007795 chemical reaction product Substances 0.000 abstract 3
- 229930013930 alkaloid Natural products 0.000 abstract 2
- 239000003795 chemical substances by application Substances 0.000 abstract 2
- 150000001875 compounds Chemical class 0.000 abstract 2
- 239000011541 reaction mixture Substances 0.000 abstract 2
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 abstract 2
- VEXZGXHMUGYJMC-UHFFFAOYSA-N Hydrochloric acid Chemical compound Cl VEXZGXHMUGYJMC-UHFFFAOYSA-N 0.000 abstract 1
- 206010028980 Neoplasm Diseases 0.000 abstract 1
- FOCVUCIESVLUNU-UHFFFAOYSA-N Thiotepa Chemical compound C1CN1P(N1CC1)(=S)N1CC1 FOCVUCIESVLUNU-UHFFFAOYSA-N 0.000 abstract 1
- 239000002253 acid Substances 0.000 abstract 1
- 239000003125 aqueous solvent Substances 0.000 abstract 1
- 201000011510 cancer Diseases 0.000 abstract 1
- 229940079593 drug Drugs 0.000 abstract 1
- 239000003814 drug Substances 0.000 abstract 1
- 230000036737 immune function Effects 0.000 abstract 1
- 230000003818 metabolic dysfunction Effects 0.000 abstract 1
- 238000000034 method Methods 0.000 abstract 1
- 230000000069 prophylactic effect Effects 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
- 230000001225 therapeutic effect Effects 0.000 abstract 1
- 229960001196 thiotepa Drugs 0.000 abstract 1
- 238000005406 washing Methods 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D491/00—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
- C07D491/12—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains three hetero rings
- C07D491/14—Ortho-condensed systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
- C07F9/02—Phosphorus compounds
- C07F9/547—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom
- C07F9/553—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom having one nitrogen atom as the only ring hetero atom
- C07F9/568—Four-membered rings
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- General Chemical & Material Sciences (AREA)
- Public Health (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Biomedical Technology (AREA)
- Communicable Diseases (AREA)
- Diabetes (AREA)
- Hematology (AREA)
- Obesity (AREA)
- Oncology (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Dermatology (AREA)
- Biochemistry (AREA)
- Molecular Biology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP04022299 | 2004-09-20 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| TW200610763A true TW200610763A (en) | 2006-04-01 |
Family
ID=35501129
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| TW094132316A TW200610763A (en) | 2004-09-20 | 2005-09-19 | Quaternary alkaloid derivatives |
Country Status (5)
| Country | Link |
|---|---|
| EP (1) | EP1833839A1 (zh) |
| AR (1) | AR050648A1 (zh) |
| CA (1) | CA2593202A1 (zh) |
| TW (1) | TW200610763A (zh) |
| WO (1) | WO2006032380A1 (zh) |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN115607549A (zh) * | 2021-07-15 | 2023-01-17 | 复旦大学 | 血根碱及其衍生物在制备防治多发性硬化症药物中的应用 |
Families Citing this family (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| ITMI20131495A1 (it) | 2013-09-10 | 2015-03-11 | Ce R C Ar Di Paolo Maestri | Composizioni utili per il trattamento di tumori resistenti alla chemioterapia |
| CA2954585A1 (en) | 2014-07-17 | 2016-01-21 | Probiotical S.P.A. | Compositions comprising melatonin and flavonoids for use in the treatment of tumours resistant to chemotherapy |
| CA2977910A1 (en) | 2015-03-05 | 2016-09-09 | Probiotical S.P.A. | Compositions for use in the treatment of tumors resistant to chemotherapy |
| JP2022552566A (ja) * | 2019-10-17 | 2022-12-16 | チェンドゥ アンタイキャンサー バイオサイエンス リミテッド | ベンゾフェナントリジンアルカロイド及びその使用方法 |
| CN113549085B (zh) * | 2021-07-16 | 2022-11-22 | 湖北科技学院 | 一种天然产物6-hhc的合成方法 |
Family Cites Families (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US2670347A (en) * | 1952-01-08 | 1954-02-23 | American Cyanamid Co | Thiophosphoric acid derivatives and method of preparing the same |
| AT407833B (de) * | 1995-06-01 | 2001-06-25 | Nowicky Wassyl Dr | Mittel zur behandlung von strahlenschäden |
-
2005
- 2005-09-09 WO PCT/EP2005/009699 patent/WO2006032380A1/en not_active Ceased
- 2005-09-09 EP EP05782899A patent/EP1833839A1/en not_active Withdrawn
- 2005-09-09 CA CA002593202A patent/CA2593202A1/en not_active Abandoned
- 2005-09-19 TW TW094132316A patent/TW200610763A/zh unknown
- 2005-09-19 AR ARP050103885A patent/AR050648A1/es unknown
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN115607549A (zh) * | 2021-07-15 | 2023-01-17 | 复旦大学 | 血根碱及其衍生物在制备防治多发性硬化症药物中的应用 |
Also Published As
| Publication number | Publication date |
|---|---|
| WO2006032380A1 (en) | 2006-03-30 |
| EP1833839A1 (en) | 2007-09-19 |
| AR050648A1 (es) | 2006-11-08 |
| CA2593202A1 (en) | 2006-03-30 |
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