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TW200607859A - Oncolytic adenoviral vectors encoding GM-CSF - Google Patents

Oncolytic adenoviral vectors encoding GM-CSF

Info

Publication number
TW200607859A
TW200607859A TW094105760A TW94105760A TW200607859A TW 200607859 A TW200607859 A TW 200607859A TW 094105760 A TW094105760 A TW 094105760A TW 94105760 A TW94105760 A TW 94105760A TW 200607859 A TW200607859 A TW 200607859A
Authority
TW
Taiwan
Prior art keywords
csf
adenoviral vectors
oncolytic adenoviral
vectors encoding
adenoviral
Prior art date
Application number
TW094105760A
Other languages
Chinese (zh)
Inventor
David Leonard Ennist
Original Assignee
Cell Genesys Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US10/925,205 external-priority patent/US20050186178A1/en
Application filed by Cell Genesys Inc filed Critical Cell Genesys Inc
Publication of TW200607859A publication Critical patent/TW200607859A/en

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  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)

Abstract

Selectively replicating oncolytic adenoviral vectors comprising an adenoviral packaging signal a termination signal sequence, an E2F responsive promoter operably linked to an adenoviral coding region, a heterologous coding sequence encoding GM-CSF and a right ITR are provided. The oncolytic adenoviral vectors are useful for expressing GM-CSF in transduced cells and in methods for selectively killing neoplastic cells.
TW094105760A 2004-08-23 2005-02-25 Oncolytic adenoviral vectors encoding GM-CSF TW200607859A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US10/925,205 US20050186178A1 (en) 2003-08-28 2004-08-23 Oncolytic adenoviral vectors encoding GM-CSF

Publications (1)

Publication Number Publication Date
TW200607859A true TW200607859A (en) 2006-03-01

Family

ID=57807368

Family Applications (1)

Application Number Title Priority Date Filing Date
TW094105760A TW200607859A (en) 2004-08-23 2005-02-25 Oncolytic adenoviral vectors encoding GM-CSF

Country Status (1)

Country Link
TW (1) TW200607859A (en)

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US11497781B2 (en) 2016-03-10 2022-11-15 Cg Oncology, Inc. Methods of treating bladder cancer by combination therapy comprising the oncolytic adenovirus CG0070 and an immune checkpoint inhibitor
US11596660B2 (en) 2017-04-14 2023-03-07 Cg Oncology, Inc. Methods of treating bladder cancer

Cited By (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US11497781B2 (en) 2016-03-10 2022-11-15 Cg Oncology, Inc. Methods of treating bladder cancer by combination therapy comprising the oncolytic adenovirus CG0070 and an immune checkpoint inhibitor
US12090183B2 (en) 2016-03-10 2024-09-17 Cg Oncology, Inc. Methods of treating solid or lymphatic tumors by combination therapy
US11596660B2 (en) 2017-04-14 2023-03-07 Cg Oncology, Inc. Methods of treating bladder cancer
US12370229B2 (en) 2017-04-14 2025-07-29 Cg Oncology, Inc. Methods of treating bladder cancer

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