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TW200606154A - Mercaptoimidazoles as CCR2 receptor antagonists - Google Patents

Mercaptoimidazoles as CCR2 receptor antagonists

Info

Publication number
TW200606154A
TW200606154A TW094116985A TW94116985A TW200606154A TW 200606154 A TW200606154 A TW 200606154A TW 094116985 A TW094116985 A TW 094116985A TW 94116985 A TW94116985 A TW 94116985A TW 200606154 A TW200606154 A TW 200606154A
Authority
TW
Taiwan
Prior art keywords
6alkyl
nr6ar6b
represents hydrogen
polyhaloc1
6alkyloxy
Prior art date
Application number
TW094116985A
Other languages
English (en)
Inventor
Gustaaf Maria Boeckx
Lommen Guy Rosalia Eugeen Van
Julien Georges Pierre-Olivier Doyon
Erwin Coesemans
Original Assignee
Janssen Pharmaceutica Nv
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=34957884&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=TW200606154(A) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Janssen Pharmaceutica Nv filed Critical Janssen Pharmaceutica Nv
Publication of TW200606154A publication Critical patent/TW200606154A/zh

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    • C—CHEMISTRY; METALLURGY
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    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C211/00—Compounds containing amino groups bound to a carbon skeleton
    • C07C211/01—Compounds containing amino groups bound to a carbon skeleton having amino groups bound to acyclic carbon atoms
    • C07C211/26—Compounds containing amino groups bound to a carbon skeleton having amino groups bound to acyclic carbon atoms of an unsaturated carbon skeleton containing at least one six-membered aromatic ring
    • C07C211/29—Compounds containing amino groups bound to a carbon skeleton having amino groups bound to acyclic carbon atoms of an unsaturated carbon skeleton containing at least one six-membered aromatic ring the carbon skeleton being further substituted by halogen atoms or by nitro or nitroso groups
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    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/42—Oxazoles
    • A61K31/422—Oxazoles not condensed and containing further heterocyclic rings
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    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
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    • A61K31/4427—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems
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    • C07D233/54—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
    • C07D233/66—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
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    • C07D233/66—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
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    • C07D401/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
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TW094116985A 2004-05-26 2005-05-25 Mercaptoimidazoles as CCR2 receptor antagonists TW200606154A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
EP2004050933 2004-05-26

Publications (1)

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TW200606154A true TW200606154A (en) 2006-02-16

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ID=34957884

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TW094116985A TW200606154A (en) 2004-05-26 2005-05-25 Mercaptoimidazoles as CCR2 receptor antagonists

Country Status (20)

Country Link
US (1) US20070249691A1 (zh)
EP (1) EP1753758B1 (zh)
JP (1) JP2008500310A (zh)
KR (1) KR20070020070A (zh)
CN (1) CN1956980A (zh)
AR (1) AR049386A1 (zh)
AT (1) ATE425161T1 (zh)
AU (1) AU2005250156A1 (zh)
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JP2021534101A (ja) 2018-08-09 2021-12-09 ヴェルソー セラピューティクス， インコーポレイテッド Ｃｃｒ２及びｃｓｆ１ｒを標的とするためのオリゴヌクレオチド組成物ならびにその使用
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AR049386A1 (es) 2006-07-26
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EA200602193A1 (ru) 2007-04-27
WO2005118578A1 (en) 2005-12-15
MXPA06013764A (es) 2007-02-08
ATE425161T1 (de) 2009-03-15
CN1956980A (zh) 2007-05-02
MY140571A (en) 2009-12-31
BRPI0511599A (pt) 2008-01-02
KR20070020070A (ko) 2007-02-16
DE602005013216D1 (de) 2009-04-23
CA2566187A1 (en) 2005-12-15
JP2008500310A (ja) 2008-01-10
IL179518A0 (en) 2007-05-15
NO20066011L (no) 2007-02-23
EP1753758A1 (en) 2007-02-21
EP1753758B1 (en) 2009-03-11
AU2005250156A1 (en) 2005-12-15
ZA200609846B (en) 2008-07-30

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