TR201803451T4 - Olmesartan formülasyonlari. - Google Patents
Olmesartan formülasyonlari. Download PDFInfo
- Publication number
- TR201803451T4 TR201803451T4 TR2018/03451T TR201803451T TR201803451T4 TR 201803451 T4 TR201803451 T4 TR 201803451T4 TR 2018/03451 T TR2018/03451 T TR 2018/03451T TR 201803451 T TR201803451 T TR 201803451T TR 201803451 T4 TR201803451 T4 TR 201803451T4
- Authority
- TR
- Turkey
- Prior art keywords
- olmesartan
- formulations
- pharmaceutically acceptable
- acceptable salts
- amlodipine
- Prior art date
Links
- 239000005480 Olmesartan Substances 0.000 title abstract 2
- VTRAEEWXHOVJFV-UHFFFAOYSA-N olmesartan Chemical compound CCCC1=NC(C(C)(C)O)=C(C(O)=O)N1CC1=CC=C(C=2C(=CC=CC=2)C=2NN=NN=2)C=C1 VTRAEEWXHOVJFV-UHFFFAOYSA-N 0.000 title abstract 2
- 229960005117 olmesartan Drugs 0.000 title abstract 2
- 239000000203 mixture Substances 0.000 title 1
- 150000003839 salts Chemical class 0.000 abstract 2
- 239000008186 active pharmaceutical agent Substances 0.000 abstract 1
- HTIQEAQVCYTUBX-UHFFFAOYSA-N amlodipine Chemical compound CCOC(=O)C1=C(COCCN)NC(C)=C(C(=O)OC)C1C1=CC=CC=C1Cl HTIQEAQVCYTUBX-UHFFFAOYSA-N 0.000 abstract 1
- 229960000528 amlodipine Drugs 0.000 abstract 1
- 238000004090 dissolution Methods 0.000 abstract 1
- 150000002148 esters Chemical class 0.000 abstract 1
- 239000008194 pharmaceutical composition Substances 0.000 abstract 1
- 239000000546 pharmaceutical excipient Substances 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/4164—1,3-Diazoles
- A61K31/4178—1,3-Diazoles not condensed 1,3-diazoles and containing further heterocyclic rings, e.g. pilocarpine, nitrofurantoin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
- A61K9/1605—Excipients; Inactive ingredients
- A61K9/1629—Organic macromolecular compounds
- A61K9/1641—Organic macromolecular compounds obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyethylene glycol, poloxamers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2004—Excipients; Inactive ingredients
- A61K9/2022—Organic macromolecular compounds
- A61K9/2031—Organic macromolecular compounds obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyethylene glycol, polyethylene oxide, poloxamers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2072—Pills, tablets, discs, rods characterised by shape, structure or size; Tablets with holes, special break lines or identification marks; Partially coated tablets; Disintegrating flat shaped forms
- A61K9/2077—Tablets comprising drug-containing microparticles in a substantial amount of supporting matrix; Multiparticulate tablets
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicinal Preparation (AREA)
Abstract
Mevcut buluş, geliştirilmiş bir çözünme profili için olmesartan veya farmasötik olarak kabul edilebilir tuzları ve esterlerini veya kombinasyon halinde amlodipin veya farmasötik olarak kabul edilebilir tuzları gibi aktif farmasötik bileşen ve uygun yardımcı maddeleri içeren farmasötik bileşimleri sağlar
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP10172244A EP2425859A1 (en) | 2010-08-08 | 2010-08-08 | Olmesartan formulations |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| TR201803451T4 true TR201803451T4 (tr) | 2019-07-22 |
Family
ID=43242598
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| TR2018/03451T TR201803451T4 (tr) | 2010-08-08 | 2011-08-08 | Olmesartan formülasyonlari. |
Country Status (4)
| Country | Link |
|---|---|
| EP (2) | EP2425859A1 (tr) |
| ES (1) | ES2663721T3 (tr) |
| TR (1) | TR201803451T4 (tr) |
| WO (1) | WO2012020368A1 (tr) |
Families Citing this family (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP2883539A1 (en) * | 2013-12-12 | 2015-06-17 | Sanovel Ilac Sanayi ve Ticaret A.S. | Pharmaceutical combinations of olmesartan and amlodipine |
| CN105663070A (zh) * | 2014-11-21 | 2016-06-15 | 深圳信立泰药业股份有限公司 | 一种含有奥美沙坦酯的药物组合物及其制备方法 |
| CN114191402A (zh) * | 2022-01-17 | 2022-03-18 | 成都恒瑞制药有限公司 | 苯磺酸氨氯地平片制备方法 |
| CN114609289B (zh) * | 2022-02-24 | 2023-11-14 | 云南龙津康佑生物医药有限公司 | 一种奥美沙坦酯氨氯地平复方制剂中杂质的检测方法 |
Family Cites Families (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB8608335D0 (en) | 1986-04-04 | 1986-05-08 | Pfizer Ltd | Pharmaceutically acceptable salts |
| CA2061607C (en) | 1991-02-21 | 1999-01-19 | Hiroaki Yanagisawa | 1-biphenylimidazole derivatives, their preparation and their therapeutic use |
| US20100119607A1 (en) * | 2005-04-18 | 2010-05-13 | Rubicon Research Pvt. Ltd. | Bioenhanced compositions |
| CN101247832B (zh) | 2005-06-27 | 2011-12-28 | 第一三共株式会社 | 含有血管紧张素ⅱ受体拮抗剂和钙通道阻断剂的药物制剂 |
| WO2007001065A2 (en) * | 2005-06-27 | 2007-01-04 | Daiichi Sankyo Company, Limited | Method for the preparation of a wet granulated drug product |
| US20100237530A1 (en) | 2006-06-27 | 2010-09-23 | Daiichi Sankyo Company, Limited | Compressed preparation |
| KR20090027734A (ko) | 2006-07-27 | 2009-03-17 | (주)아모레퍼시픽 | 난용성 약물의 나노입자를 포함하는 분말의 제조방법 |
| TWI399223B (zh) * | 2006-09-15 | 2013-06-21 | Daiichi Sankyo Co Ltd | 奧美沙坦酯及氨氯地平之固體劑型 |
| US20100278909A1 (en) | 2007-06-06 | 2010-11-04 | Dexcel Ltd. | Process for forming solid oral dosage forms of angiotensin ii receptor antagonists |
| WO2009084040A1 (en) * | 2007-12-28 | 2009-07-09 | Rubicon Research Private Limited | Once a day formulation of angiotensin receptor blockers |
| WO2009110010A2 (en) * | 2008-03-07 | 2009-09-11 | Sun Pharmaceutical Industries Ltd. | Stable oral dosage form |
-
2010
- 2010-08-08 EP EP10172244A patent/EP2425859A1/en not_active Withdrawn
-
2011
- 2011-08-08 WO PCT/IB2011/053532 patent/WO2012020368A1/en not_active Ceased
- 2011-08-08 EP EP11754742.2A patent/EP2637695B1/en active Active
- 2011-08-08 TR TR2018/03451T patent/TR201803451T4/tr unknown
- 2011-08-08 ES ES11754742.2T patent/ES2663721T3/es active Active
Also Published As
| Publication number | Publication date |
|---|---|
| EP2637695B1 (en) | 2017-12-13 |
| EP2425859A1 (en) | 2012-03-07 |
| WO2012020368A1 (en) | 2012-02-16 |
| ES2663721T3 (es) | 2018-04-16 |
| EP2637695A1 (en) | 2013-09-18 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| EA201201263A1 (ru) | Фармацевтическая композиция, содержащая этексилат дабигатрана | |
| CR20110110A (es) | Composicion farmaceutica | |
| SG194756A1 (en) | Modified release of 4-methyl-3-[[4-(3-pyridinyl)-2-pyrimidinyl]amino]-n-5-(4-methyl-1h-imidazol-1-yl)-3-(trifluoromethyl)phenyl] benzamide solubilized using organic acids | |
| EA201390662A1 (ru) | Фармацевтическая композиция, содержащая дутастерид | |
| EA201201202A1 (ru) | Пероральная фармацевтическая композиция, содержащая этексилат дабигатрана | |
| IL222578A0 (en) | Method for preparing pharmaceutical compositions intended for oral administration comprising one or more active ingredients and the compositions comprising same | |
| PH12015501096A1 (en) | Composition for immediate and extended release | |
| EA201690679A1 (ru) | Стабильная фармацевтическая композиция, содержащая амлодипин и валсартан | |
| NI201100227A (es) | Composiciones de dosis fija farmacéuticas sólidas que comprenden irbesartán y amlodipina, su preparación y su aplicación terapéutica. | |
| WO2014016754A3 (en) | Pharmaceutical compositions of proton pump inhibitor | |
| WO2012085284A3 (en) | High drug load pharmaceutical formulations comprising dronedarone and its pharmaceutically acceptable salts | |
| TR201009394A2 (tr) | Geliştirilmiş montelukast formülasyonları. | |
| JO3587B1 (ar) | أشكال جرعات بينداموستين عن طريق الفم | |
| TR201803451T4 (tr) | Olmesartan formülasyonlari. | |
| WO2012085249A3 (en) | Homogenous pharmaceutical oral dosage forms comprising lercanidipine and enalapril or their pharmaceutically acceptable salts together with an organic acid | |
| UA105285C2 (uk) | Тверда фармацевтична композиція раміприлу і безилату амлодипіну і її отримання | |
| IT1401284B1 (it) | Nuove formulazioni farmaceutiche idonee per la somministrazione orale di esomeprazolo magnesio diidrato, in forma di compresse mups (multi unit pellets system). | |
| TR200604349A2 (tr) | Aripiprazol içeren farmasötik bileşimler | |
| TR200909785A1 (tr) | Aktif ajan olarak sefdinir içeren farmasötik kompozisyonlar. | |
| MX2012007393A (es) | Composicion farmaceutica de disolucion rapida comprendiendo lornoxicam. | |
| TR201009399A2 (tr) | Hızlı çözünen efervesan rosuvastatin formülasyonları. | |
| TR201100152A2 (tr) | Amlodipin içeren efervesan bileşimler. | |
| TR201002084A1 (tr) | Oral yolla dağılan donepezil tablet formülasyonları ve hazırlama yöntemi | |
| WO2011161223A3 (en) | Pharmaceutical oral dosage forms comprising lercanidipine and enalapril and their pharmaceutically acceptable salts | |
| TR201008517A2 (tr) | Olmesartan medoksomil içeren ilaç formülasyonu. |