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TR200302265T1 - Process for the production of substituted phenyl ethers - Google Patents

Process for the production of substituted phenyl ethers

Info

Publication number
TR200302265T1
TR200302265T1 TR2003/02265T TR200302265T TR200302265T1 TR 200302265 T1 TR200302265 T1 TR 200302265T1 TR 2003/02265 T TR2003/02265 T TR 2003/02265T TR 200302265 T TR200302265 T TR 200302265T TR 200302265 T1 TR200302265 T1 TR 200302265T1
Authority
TR
Turkey
Prior art keywords
production
substituted phenyl
phenyl ethers
compound
formula
Prior art date
Application number
TR2003/02265T
Other languages
Turkish (tr)
Inventor
Adiyaman Mustafa
Güner Di̇dem
Yurdakul Ayci̇l
Ridvanoğlu Nurten
Original Assignee
Eös Eczacibaşi Özgün Ki̇myasal Ürünler San. Ve Ti̇c. A.Ş.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Eös Eczacibaşi Özgün Ki̇myasal Ürünler San. Ve Ti̇c. A.Ş. filed Critical Eös Eczacibaşi Özgün Ki̇myasal Ürünler San. Ve Ti̇c. A.Ş.
Publication of TR200302265T1 publication Critical patent/TR200302265T1/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/24—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with substituted hydrocarbon radicals attached to ring carbon atoms
    • C07D213/28—Radicals substituted by singly-bound oxygen or sulphur atoms
    • C07D213/30—Oxygen atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
    • C07D417/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a chain containing hetero atoms as chain links

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Pyridine Compounds (AREA)

Abstract

Bu bulus sübstitüye fenil eterlerin üretimi için gelistirilmis bir prosesi açiklar. Bu bulus özellikle asagidaki Formül 1 ile gösterilen bilesigin elde edilmesi için bir prosesi ihtiva eder: FORMÜL 1 burada H1 bir sübstitüye pridil grubudur ve R1 aldehit, siyano veya nitro grubu olabilir. Formülde gösterilen bilesik I, pioglitazone, rosiglitazone gibi farmakolojik olarak faydali tiyazolidindion türevlerinin hazirlanmasinda çok önemli bir ara maddedir.This invention discloses an improved process for the production of substituted phenyl ethers. In particular, the present invention includes a process for obtaining the compound of Formula I: ## STR4 ## wherein H1 is a substituted pyridyl group and R1 may be an aldehyde, cyano or nitro group. The compound I shown in the formula is a very important intermediate in the preparation of pharmacologically useful thiazolidinedione derivatives such as pioglitazone, rosiglitazone.

TR2003/02265T 2002-06-19 2002-06-19 Process for the production of substituted phenyl ethers TR200302265T1 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
PCT/TR2002/000025 WO2004000810A1 (en) 2002-06-19 2002-06-19 A process for the production of substituted phenyl ethers

Publications (1)

Publication Number Publication Date
TR200302265T1 true TR200302265T1 (en) 2004-08-23

Family

ID=29997778

Family Applications (1)

Application Number Title Priority Date Filing Date
TR2003/02265T TR200302265T1 (en) 2002-06-19 2002-06-19 Process for the production of substituted phenyl ethers

Country Status (3)

Country Link
AU (1) AU2002345524A1 (en)
TR (1) TR200302265T1 (en)
WO (1) WO2004000810A1 (en)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2005073227A2 (en) * 2004-01-28 2005-08-11 Usv Limited A process for the preparation of 5-[4-[2-[n-methyl-n-(2-pyridyl) amino] ethoxy] phenyl methyl] thiazolidine-2, 4-dione maleate
US20090149508A1 (en) * 2005-07-27 2009-06-11 Sandoz Ag Process for the preparation of substituted phenyl ether compounds
JP5096369B2 (en) 2005-12-20 2012-12-12 ブリストル−マイヤーズ スクイブ カンパニー Composition and method for producing the composition
WO2009104200A1 (en) * 2008-02-21 2009-08-27 Biocon Limited A method for preparation of thiazolidinedione derivatives

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4812570A (en) * 1986-07-24 1989-03-14 Takeda Chemical Industries, Ltd. Method for producing thiazolidinedione derivatives
ATE123278T1 (en) * 1991-03-25 1995-06-15 Takeda Chemical Industries Ltd METHOD FOR PRODUCING ETHERS.
US5952509A (en) * 1996-06-27 1999-09-14 Takeda Chemical Industries, Ltd. Production of benzaldehyde compounds

Also Published As

Publication number Publication date
AU2002345524A1 (en) 2004-01-06
WO2004000810A1 (en) 2003-12-31

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