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TR200201244T2 - Göz kurumasının iyileştirilmesi için Lipoksin A4 ve analogları - Google Patents

Göz kurumasının iyileştirilmesi için Lipoksin A4 ve analogları

Info

Publication number
TR200201244T2
TR200201244T2 TR2002/01244T TR200201244T TR200201244T2 TR 200201244 T2 TR200201244 T2 TR 200201244T2 TR 2002/01244 T TR2002/01244 T TR 2002/01244T TR 200201244 T TR200201244 T TR 200201244T TR 200201244 T2 TR200201244 T2 TR 200201244T2
Authority
TR
Turkey
Prior art keywords
analogs
lipoxin
eye dryness
improve eye
improve
Prior art date
Application number
TR2002/01244T
Other languages
English (en)
Inventor
A. Gamache Daniel
Graff Gustav
R. Hellberg Mark
G. Klimko Peter
M. Yanni John
Original Assignee
Alcon, Inc.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Alcon, Inc. filed Critical Alcon, Inc.
Publication of TR200201244T2 publication Critical patent/TR200201244T2/tr

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19—Carboxylic acids, e.g. valproic acid
    • A61K31/20—Carboxylic acids, e.g. valproic acid having a carboxyl group bound to a chain of seven or more carbon atoms, e.g. stearic, palmitic, arachidic acids
    • A61K31/202—Carboxylic acids, e.g. valproic acid having a carboxyl group bound to a chain of seven or more carbon atoms, e.g. stearic, palmitic, arachidic acids having three or more double bonds, e.g. linolenic
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/557—Eicosanoids, e.g. leukotrienes or prostaglandins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0048—Eye, e.g. artificial tears
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents

Landscapes

  • Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Epidemiology (AREA)
  • Ophthalmology & Optometry (AREA)
  • Organic Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Engineering & Computer Science (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicinal Preparation (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Peptides Or Proteins (AREA)

Abstract

Lipoksin A4 ve analoglarini ihtiva eden oftalmik bilesimler ve bu bilesimlerin göz kurumasinin iyilestirilmesi için kullanim yöntemleri anatilmistir.
TR2002/01244T 1999-11-09 2000-11-08 Göz kurumasının iyileştirilmesi için Lipoksin A4 ve analogları TR200201244T2 (tr)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US16440699P 1999-11-09 1999-11-09

Publications (1)

Publication Number Publication Date
TR200201244T2 true TR200201244T2 (tr) 2002-08-21

Family

ID=22594348

Family Applications (2)

Application Number Title Priority Date Filing Date
TR2004/00526T TR200400526T4 (tr) 1999-11-09 2000-11-08 Göz kurumasının tedavisi için lipoksin A4 ve analogları
TR2002/01244T TR200201244T2 (tr) 1999-11-09 2000-11-08 Göz kurumasının iyileştirilmesi için Lipoksin A4 ve analogları

Family Applications Before (1)

Application Number Title Priority Date Filing Date
TR2004/00526T TR200400526T4 (tr) 1999-11-09 2000-11-08 Göz kurumasının tedavisi için lipoksin A4 ve analogları

Country Status (17)

Country Link
US (1) US6645978B1 (tr)
EP (1) EP1237549B1 (tr)
JP (1) JP2003514782A (tr)
CN (1) CN1387435A (tr)
AT (1) ATE258791T1 (tr)
AU (1) AU1475701A (tr)
BR (1) BR0015392A (tr)
CA (1) CA2386878A1 (tr)
DE (1) DE60008143T2 (tr)
DK (1) DK1237549T3 (tr)
ES (1) ES2215752T3 (tr)
HK (1) HK1046365A1 (tr)
MX (1) MXPA02004617A (tr)
PL (1) PL356100A1 (tr)
PT (1) PT1237549E (tr)
TR (2) TR200400526T4 (tr)
WO (1) WO2001034144A1 (tr)

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Publication number Priority date Publication date Assignee Title
US8722654B2 (en) * 2001-03-02 2014-05-13 The Brigham And Women's Hospital, Inc. Lipoxin analogs as novel inhibitors of angiogenesis
MXPA04003299A (es) * 2001-10-11 2004-07-23 Alcon Inc Metodos para tratar la resequedad ocular mediante una combinacion de un esteroide antiinflamatorio y un secretagogo muc-1.
US6831186B2 (en) 2001-11-06 2004-12-14 Schering Aktiengesellschft Lipoxin A4 analogs
US7795203B2 (en) * 2002-09-30 2010-09-14 Babizhayev Mark A Method for topical treatment of eye disease and composition and device for said treatment
US20050208102A1 (en) * 2003-04-09 2005-09-22 Schultz Clyde L Hydrogels used to deliver medicaments to the eye for the treatment of posterior segment diseases
US9216106B2 (en) * 2003-04-09 2015-12-22 Directcontact Llc Device and method for the delivery of drugs for the treatment of posterior segment disease
US20050255144A1 (en) * 2003-04-09 2005-11-17 Directcontact Llc Methods and articles for the delivery of medicaments to the eye for the treatment of posterior segment diseases
US20050074497A1 (en) * 2003-04-09 2005-04-07 Schultz Clyde L. Hydrogels used to deliver medicaments to the eye for the treatment of posterior segment diseases
SI1744736T1 (sl) * 2004-05-14 2010-01-29 Alcon Inc Postopek za zdravljenje težav s suhimi očmi in uveitisa
US7923471B2 (en) 2004-05-14 2011-04-12 Alcon, Inc. Method of treating dry eye disorders and uveitis
DE602005018515D1 (de) * 2004-10-01 2010-02-04 Menicon Co Ltd Verfahren zur sterilisation verpackter kontaktlinsen mit verpackungslösung
PL1809270T3 (pl) * 2004-11-09 2010-08-31 Alcon Inc Kwas 5,6,7-trihydroksyheptanowy i jego analogi do leczenia chorób oczu i chorób związanych z odpowiedziami hiperproliferacyjnymi i angiogenicznymi
US20060134171A1 (en) * 2004-12-16 2006-06-22 Alcon, Inc. Agents which regulate, inhibit, or modulate the activity and/or expression of formyl peptide receptors as a unique means to both lower intraocular pressure and treat glaucomatous retinopathies/optic neuropathies
US20060154981A1 (en) * 2005-01-12 2006-07-13 Alcon, Inc. Method of reducing intraocular pressure and treating glaucoma
US7687539B1 (en) 2005-11-07 2010-03-30 Alcon Research, Ltd. Method of treating ocular allergy
UY30755A1 (es) 2006-12-04 2008-07-31 Bayer Schering Pharma Ag Sal de potasio cristalina de analogos de lipoxina a4
AU2014201375B2 (en) * 2007-10-12 2015-11-05 Resolvyx Pharmaceuticals, Inc. Omega-3 fatty acids, hydroxy polyunsaturated fatty acids, lipoxin compounds, or oxylipin compounds for the treatment of ophthalmic conditions
US20090118243A1 (en) * 2007-10-12 2009-05-07 Resolvyx Pharmaceuticals, Inc. Compositions and methods for the treatment of ophthalmic conditions
CA2712970A1 (en) * 2007-10-29 2009-05-07 Board Of Supervisors Of Louisiana State University And Agricultural And Mechanical College Lipoxin a4 protection for retinal cells
AU2008318646B2 (en) * 2007-10-30 2014-09-25 Board Of Supervisors Of Louisiana State University And Agricultural And Mechanical College Lipoxin A4 protection for cornea endothelial cells
US8865685B2 (en) * 2011-06-30 2014-10-21 Johnson & Johnson Vision Care, Inc. Esters for treatment of ocular inflammatory conditions
US20180116990A1 (en) * 2016-10-04 2018-05-03 UND Life Sciences, LLC Composition of bioactive lipids and methods of use thereof
CA3055093A1 (en) * 2017-03-09 2018-09-13 University Health Network Lipoxin and lipoxin analogue mediated neuroprotection and treatments

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US3991759A (en) 1975-10-28 1976-11-16 Alza Corporation Method and therapeutic system for treating aqueous deficient dry eye
US4131651A (en) 1977-10-25 1978-12-26 Barnes-Hind Pharmaceuticals, Inc. Treatment of dry eye
US4409205A (en) 1979-03-05 1983-10-11 Cooper Laboratories, Inc. Ophthalmic solution
US4370325A (en) 1979-03-30 1983-01-25 Dermik Laboratories Pharmaceutical compositions and method of treatment
US4576758A (en) * 1984-06-01 1986-03-18 The Upjohn Company Anti-inflammatory lipoxin B analogs
US4868154A (en) 1986-02-19 1989-09-19 Eye Research Institute Of Retina Foundation Stimulation of tear secretion with melanocyte stimulating hormones
US4753945A (en) 1986-02-19 1988-06-28 Eye Research Institute Of Retina Foundation Stimulation of tear secretion with phosphodiesterase inhibitors
US4883658A (en) 1986-04-28 1989-11-28 Holly Frank J Ophthalmic solution for treatment of dry-eye syndrome
US4744980A (en) 1986-04-28 1988-05-17 Holly Frank J Ophthalmic solution for treatment of dry eye syndrome
US4804539A (en) 1986-07-28 1989-02-14 Liposome Technology, Inc. Ophthalmic liposomes
US4818537A (en) 1986-10-21 1989-04-04 Liposome Technology, Inc. Liposome composition for treating dry eye
US4966773A (en) 1986-11-25 1990-10-30 Alcon Laboratories, Inc. Topical ophthalmic compositions containing microfine retinoid particles
US4914088A (en) 1987-04-02 1990-04-03 Thomas Glonek Dry eye treatment solution and method
US5278151A (en) 1987-04-02 1994-01-11 Ocular Research Of Boston, Inc. Dry eye treatment solution
US5075104A (en) 1989-03-31 1991-12-24 Alcon Laboratories, Inc. Ophthalmic carboxy vinyl polymer gel for dry eye syndrome
US5079261A (en) * 1989-04-28 1992-01-07 Brigham And Women's Hospital Use of lipoxin a4 and its derivatives as antagonists for slow-reacting substances of anaphylaxis
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US5041434A (en) 1991-08-17 1991-08-20 Virginia Lubkin Drugs for topical application of sex steroids in the treatment of dry eye syndrome, and methods of preparation and application
ES2084722T3 (es) 1990-05-29 1996-05-16 Boston Ocular Res Composicion para tratamiento del ojo seco.
ZA912797B (en) 1990-05-29 1992-12-30 Boston Ocular Res Dry eye treatment process and solution
ATE141502T1 (de) 1991-01-15 1996-09-15 Alcon Lab Inc Verwendung von karrageenan in topischen ophthalmologischen zusammensetzungen
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ATE185697T1 (de) 1992-04-21 1999-11-15 Schepens Eye Res Inst Androgentherapie am auge beim sjögrensyndrom
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Also Published As

Publication number Publication date
ATE258791T1 (de) 2004-02-15
EP1237549A1 (en) 2002-09-11
DK1237549T3 (da) 2004-06-07
JP2003514782A (ja) 2003-04-22
DE60008143T2 (de) 2004-12-30
TR200400526T4 (tr) 2004-04-21
MXPA02004617A (es) 2004-09-10
CN1387435A (zh) 2002-12-25
ES2215752T3 (es) 2004-10-16
PL356100A1 (en) 2004-06-14
PT1237549E (pt) 2004-06-30
AU1475701A (en) 2001-06-06
CA2386878A1 (en) 2001-05-17
US6645978B1 (en) 2003-11-11
HK1046365A1 (zh) 2003-01-10
BR0015392A (pt) 2002-06-25
WO2001034144A1 (en) 2001-05-17
DE60008143D1 (de) 2004-03-11
EP1237549B1 (en) 2004-02-04

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