TR200103708T2 - Membran sentezi ve membran nakli dahilinde corynemacterium glutamicum kodlayan proteinler - Google Patents
Membran sentezi ve membran nakli dahilinde corynemacterium glutamicum kodlayan proteinlerInfo
- Publication number
- TR200103708T2 TR200103708T2 TR2001/03708T TR200103708T TR200103708T2 TR 200103708 T2 TR200103708 T2 TR 200103708T2 TR 2001/03708 T TR2001/03708 T TR 2001/03708T TR 200103708 T TR200103708 T TR 200103708T TR 200103708 T2 TR200103708 T2 TR 200103708T2
- Authority
- TR
- Turkey
- Prior art keywords
- mct
- membrane
- glutamicum
- nucleic acid
- acid molecules
- Prior art date
Links
- 239000012528 membrane Substances 0.000 title 2
- 230000015572 biosynthetic process Effects 0.000 title 1
- 102000004169 proteins and genes Human genes 0.000 title 1
- 108090000623 proteins and genes Proteins 0.000 title 1
- 238000003786 synthesis reaction Methods 0.000 title 1
- 102000039446 nucleic acids Human genes 0.000 abstract 4
- 108020004707 nucleic acids Proteins 0.000 abstract 4
- 102000000562 Monocarboxylic Acid Transporters Human genes 0.000 abstract 3
- 108010041817 Monocarboxylic Acid Transporters Proteins 0.000 abstract 3
- 241000186226 Corynebacterium glutamicum Species 0.000 abstract 2
- -1 MCT nucleic acid Chemical class 0.000 abstract 2
- 239000013604 expression vector Substances 0.000 abstract 2
- 150000007523 nucleic acids Chemical class 0.000 abstract 2
- 230000000692 anti-sense effect Effects 0.000 abstract 1
- 230000000890 antigenic effect Effects 0.000 abstract 1
- 150000001875 compounds Chemical class 0.000 abstract 1
- 102000037865 fusion proteins Human genes 0.000 abstract 1
- 108020001507 fusion proteins Proteins 0.000 abstract 1
- 238000010353 genetic engineering Methods 0.000 abstract 1
- 238000004519 manufacturing process Methods 0.000 abstract 1
- 238000000034 method Methods 0.000 abstract 1
- 102000004196 processed proteins & peptides Human genes 0.000 abstract 1
- 108090000765 processed proteins & peptides Proteins 0.000 abstract 1
- 238000003259 recombinant expression Methods 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/195—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
- C07K14/34—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Corynebacterium (G)
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Genetics & Genomics (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Biomedical Technology (AREA)
- Molecular Biology (AREA)
- Biotechnology (AREA)
- General Engineering & Computer Science (AREA)
- Biochemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Health & Medical Sciences (AREA)
- Wood Science & Technology (AREA)
- Zoology (AREA)
- Biophysics (AREA)
- Physics & Mathematics (AREA)
- Microbiology (AREA)
- Plant Pathology (AREA)
- Gastroenterology & Hepatology (AREA)
- Medicinal Chemistry (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Peptides Or Proteins (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
Abstract
Corynebacterium glutamicum'dan türetilmis yeni MCT proteinlerini sifreleyen MCT nükleik asit molekülleri adli izole edilmis nükleik asit molekülleri tarif edilmektedir. Bulus anti duyarli nükleik asit molekülleri, MCT nükleik asit molekülleri ihtiva eden yeniden birlestirici tanim vektörleri ve tanim vektörlerinin yerlestirildigi konakçi hücreler de saglar. Hali hazirda bulus ayrica izole edilmis MCT proteinleri, mutasyon geçirmis MCT proteinleri, füzyon proteinleri, antijenik peptidler ve bu organizmadaki MCT genlerinin genetik mühendisligine dayanarak arzu edilen bir bilesigin C.Glutamicum'dan üretiminin gelistirlmesine yönelik metotlar saglar.
Applications Claiming Priority (35)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US14103199P | 1999-06-25 | 1999-06-25 | |
| DE19931454 | 1999-07-08 | ||
| DE19931563 | 1999-07-08 | ||
| DE19931478 | 1999-07-08 | ||
| DE19932124 | 1999-07-09 | ||
| DE19932180 | 1999-07-09 | ||
| DE19932182 | 1999-07-09 | ||
| DE19932228 | 1999-07-09 | ||
| DE19932190 | 1999-07-09 | ||
| DE19932209 | 1999-07-09 | ||
| DE19932128 | 1999-07-09 | ||
| DE19932125 | 1999-07-09 | ||
| DE19932227 | 1999-07-09 | ||
| DE19932212 | 1999-07-09 | ||
| DE19932191 | 1999-07-09 | ||
| DE19932230 | 1999-07-09 | ||
| DE19932122 | 1999-07-09 | ||
| DE19932229 | 1999-07-09 | ||
| DE19933006 | 1999-07-14 | ||
| DE19932927 | 1999-07-14 | ||
| DE19933005 | 1999-07-14 | ||
| DE19940830 | 1999-08-27 | ||
| DE19940832 | 1999-08-27 | ||
| DE19940833 | 1999-08-27 | ||
| DE19940764 | 1999-08-27 | ||
| DE19940765 | 1999-08-27 | ||
| DE19940831 | 1999-08-27 | ||
| DE19940766 | 1999-08-27 | ||
| DE19941379 | 1999-08-31 | ||
| DE19941395 | 1999-08-31 | ||
| DE19941378 | 1999-08-31 | ||
| DE19942088 | 1999-09-03 | ||
| DE19942078 | 1999-09-03 | ||
| DE19942077 | 1999-09-03 | ||
| DE19942079 | 1999-09-03 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| TR200103708T2 true TR200103708T2 (tr) | 2002-08-21 |
Family
ID=27586932
Family Applications (4)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| TR2001/03708T TR200103708T2 (tr) | 1999-06-25 | 2000-06-23 | Membran sentezi ve membran nakli dahilinde corynemacterium glutamicum kodlayan proteinler |
| TR2006/07441T TR200607441T2 (tr) | 1999-06-25 | 2000-06-23 | Membran sentezi ve membran nakli dahilinde corynemacterium glutamicum kodlayan proteinler. |
| TR2006/07443T TR200607443T2 (tr) | 1999-06-25 | 2000-06-23 | Membran sentezi ve membran nakli dahilinde corynebacterium glutamicum kodlayan proteinler |
| TR2006/07442T TR200607442T2 (tr) | 1999-06-25 | 2000-06-23 | Membran sentezi ve membran nakli dahilinde corynemacterium glutamicum kodlayan proteinler. |
Family Applications After (3)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| TR2006/07441T TR200607441T2 (tr) | 1999-06-25 | 2000-06-23 | Membran sentezi ve membran nakli dahilinde corynemacterium glutamicum kodlayan proteinler. |
| TR2006/07443T TR200607443T2 (tr) | 1999-06-25 | 2000-06-23 | Membran sentezi ve membran nakli dahilinde corynebacterium glutamicum kodlayan proteinler |
| TR2006/07442T TR200607442T2 (tr) | 1999-06-25 | 2000-06-23 | Membran sentezi ve membran nakli dahilinde corynemacterium glutamicum kodlayan proteinler. |
Country Status (10)
| Country | Link |
|---|---|
| EP (1) | EP1255839A2 (tr) |
| JP (2) | JP2004513603A (tr) |
| KR (3) | KR100834989B1 (tr) |
| CA (1) | CA2380863A1 (tr) |
| CZ (1) | CZ20014660A3 (tr) |
| ES (1) | ES2177476T1 (tr) |
| MX (1) | MXPA01012845A (tr) |
| SK (1) | SK18912001A3 (tr) |
| TR (4) | TR200103708T2 (tr) |
| WO (1) | WO2001000805A2 (tr) |
Families Citing this family (31)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6893852B1 (en) | 1999-07-02 | 2005-05-17 | Ajinomoto Co., Inc. | Dna encoding sucrose pts enzyme II |
| DE19941478A1 (de) * | 1999-09-01 | 2001-03-08 | Degussa | Neue für das thrE-Gen codierende Nukleotidsequenzen und Verfahren zur fermentativen Herstellung von L-Threonin mit coryneformen Bakterien |
| DE10021831A1 (de) * | 2000-05-04 | 2001-11-08 | Degussa | Neue für das fadD15-Gen kodierende Nukleotidsequenzen |
| DE10021826A1 (de) * | 2000-05-04 | 2001-11-08 | Degussa | Neue für das cls-Gen kodierende Nukleotidsequenzen |
| US6562607B2 (en) | 2000-05-04 | 2003-05-13 | Degussa-Huls Aktiengesellschaft | Nucleotide sequences coding for the cls gene |
| DE10021829A1 (de) * | 2000-05-04 | 2001-11-08 | Degussa | Neue für das pgsA2-Gen kodierende Nukleotidsequenzen |
| DE10021832A1 (de) * | 2000-05-04 | 2001-11-08 | Degussa | Neue für das cma-Gen kodierende Nukleotidsequenzen |
| DE10021828A1 (de) * | 2000-05-04 | 2001-11-08 | Degussa | Neue für das cdsA-Gen kodierende Nukleotidsequenzen |
| DE10023400A1 (de) | 2000-05-12 | 2001-11-15 | Degussa | Neue für das acp-Gen kodierende Nukleotidsequenzen |
| US20020081673A1 (en) * | 2000-06-02 | 2002-06-27 | Bettina Mockel | Novel nucleotide sequences coding for the glbO gene |
| DE10032173A1 (de) * | 2000-07-01 | 2002-01-17 | Degussa | Neue für das plsC-Gen kodierende Nukleotidsequenzen |
| DE10045579A1 (de) * | 2000-09-15 | 2002-04-11 | Degussa | Neue für das atr61-Gen kodierende Nukleotidsequenzen |
| AU2001293731A1 (en) * | 2000-09-19 | 2002-04-02 | Degussa A.G. | Nucleotide sequences coding for the dcta gene |
| DE10057801A1 (de) * | 2000-11-22 | 2002-05-23 | Degussa | Neue für das cysQ-Gen kodierende Nukleotidsequenzen |
| DE10154270A1 (de) | 2001-11-05 | 2003-05-15 | Basf Ag | Gene die für Kohlenstoffmetabolismus- und Energieproduktion-Proteine codieren |
| DE10154179A1 (de) * | 2001-11-05 | 2003-05-08 | Basf Ag | Gene die für membeansynthese-und Membrantransport-Proteine codieren |
| DE10163167A1 (de) * | 2001-12-21 | 2003-07-03 | Degussa | Verfahren zur fermentativen Herstellung von L-Aminosäuren und Verwendung coryneformer Bakterien |
| DE60333285D1 (de) * | 2002-05-14 | 2010-08-19 | Martek Biosciences Corp | Carotinsynthase-gen und dessen verwendung |
| US7468262B2 (en) | 2003-05-16 | 2008-12-23 | Ajinomoto Co., Inc. | Polynucleotides encoding useful polypeptides in corynebacterium glutamicum ssp. lactofermentum |
| DE102004009454A1 (de) * | 2004-02-27 | 2005-09-15 | Degussa Ag | Verfahren zur fermentativen Herstellung von L-Aminosäuren unter Verwendung von rekombinanten Mikroorganismen |
| JP5493854B2 (ja) * | 2007-04-10 | 2014-05-14 | 味の素株式会社 | 有機酸の製造方法 |
| KR101694850B1 (ko) * | 2014-10-08 | 2017-01-10 | 씨제이제일제당 주식회사 | L-글루타민을 생산하는 미생물 및 이를 이용한 l-글루타민 생산방법 |
| CN110035991B (zh) * | 2017-04-04 | 2022-06-17 | Nnb营养品美国有限公司 | 一步发酵制备(r)-3-羟基丁酸或其盐 |
| KR101968317B1 (ko) * | 2018-02-23 | 2019-04-11 | 씨제이제일제당 주식회사 | 신규 l-트립토판 배출 단백질 및 이를 이용한 l-트립토판을 생산하는 방법 |
| WO2019228937A1 (en) * | 2018-05-28 | 2019-12-05 | Universitaet Des Saarlandes | Means and methods for the production of glutarate |
| EP3670525A1 (en) * | 2018-12-18 | 2020-06-24 | Evonik Operations GmbH | Method for the fermentative production of l-lysine using c. glutamicum strains with a mutated kup transporter |
| CN112143676B (zh) * | 2020-09-21 | 2022-03-18 | 山西大学 | 一株产碱性蛋白酶耐盐芽孢杆菌及其产碱性蛋白酶的方法与应用 |
| CN112646766B (zh) * | 2020-12-30 | 2023-08-18 | 内蒙古伊品生物科技有限公司 | 一种改造基因bbd29_04920的产l-谷氨酸的重组菌株及其构建方法与应用 |
| CN114763372B (zh) * | 2021-01-13 | 2024-12-10 | 中国科学院天津工业生物技术研究所 | 具有l-脯氨酸外排功能的蛋白及其应用 |
| KR102261851B1 (ko) * | 2021-01-15 | 2021-06-04 | 씨제이제일제당 (주) | 신규한 abc 트랜스포터 atp-결합 단백질 변이체 및 이를 이용한 l-라이신 생산 방법 |
| CN119432690B (zh) * | 2024-09-13 | 2025-11-04 | 华南理工大学 | 利用co2电化学衍生物生产pha的盐单胞菌及其构建方法和应用 |
Family Cites Families (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| IT1196453B (it) * | 1986-07-04 | 1988-11-16 | Sclavo Spa | Elemento di dna di corynebacterium diphtheriae con proprieta' tipiche di un elemento di inserzione is |
| US6649379B1 (en) * | 1987-06-12 | 2003-11-18 | Massachusetts Institute Of Technology | Method and deregulated enzyme for threonine production |
| JP2967996B2 (ja) * | 1989-06-06 | 1999-10-25 | 協和醗酵工業株式会社 | L―トリプトファンの製造法 |
| MY113040A (en) * | 1994-02-24 | 2001-11-30 | Ajinomoto Kk | Novel gene derived from coryneform bacteria and use thereof |
| US6737248B2 (en) * | 1996-01-05 | 2004-05-18 | Human Genome Sciences, Inc. | Staphylococcus aureus polynucleotides and sequences |
-
2000
- 2000-06-23 CZ CZ20014660A patent/CZ20014660A3/cs unknown
- 2000-06-23 TR TR2001/03708T patent/TR200103708T2/tr unknown
- 2000-06-23 SK SK1891-2001A patent/SK18912001A3/sk not_active Application Discontinuation
- 2000-06-23 KR KR1020017016590A patent/KR100834989B1/ko not_active Expired - Fee Related
- 2000-06-23 JP JP2001506799A patent/JP2004513603A/ja active Pending
- 2000-06-23 CA CA002380863A patent/CA2380863A1/en not_active Abandoned
- 2000-06-23 WO PCT/IB2000/000926 patent/WO2001000805A2/en not_active Ceased
- 2000-06-23 KR KR1020067022650A patent/KR100878332B1/ko not_active Expired - Fee Related
- 2000-06-23 TR TR2006/07441T patent/TR200607441T2/tr unknown
- 2000-06-23 KR KR1020077015871A patent/KR20070087032A/ko not_active Withdrawn
- 2000-06-23 TR TR2006/07443T patent/TR200607443T2/tr unknown
- 2000-06-23 MX MXPA01012845A patent/MXPA01012845A/es not_active Application Discontinuation
- 2000-06-23 EP EP00939001A patent/EP1255839A2/en not_active Ceased
- 2000-06-23 ES ES00939001T patent/ES2177476T1/es active Pending
- 2000-06-23 TR TR2006/07442T patent/TR200607442T2/tr unknown
-
2006
- 2006-05-11 JP JP2006132306A patent/JP2006271389A/ja not_active Withdrawn
Also Published As
| Publication number | Publication date |
|---|---|
| TR200607441T2 (tr) | 2007-02-21 |
| KR20060118626A (ko) | 2006-11-23 |
| KR100878332B1 (ko) | 2009-01-14 |
| WO2001000805A2 (en) | 2001-01-04 |
| ES2177476T1 (es) | 2002-12-16 |
| WO2001000805A3 (en) | 2001-10-25 |
| TR200607442T2 (tr) | 2007-02-21 |
| SK18912001A3 (sk) | 2002-10-08 |
| KR20030002295A (ko) | 2003-01-08 |
| EP1255839A2 (en) | 2002-11-13 |
| CZ20014660A3 (cs) | 2002-09-11 |
| MXPA01012845A (es) | 2002-07-09 |
| JP2006271389A (ja) | 2006-10-12 |
| KR100834989B1 (ko) | 2008-06-03 |
| CA2380863A1 (en) | 2001-01-04 |
| KR20070087032A (ko) | 2007-08-27 |
| TR200607443T2 (tr) | 2007-10-22 |
| JP2004513603A (ja) | 2004-05-13 |
| TR200607443T1 (tr) | 2007-04-24 |
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