[go: up one dir, main page]

TR200102337T2 - Optik açıdan aktif aminlerin rasemleştirilmesine ilişkin yöntem. - Google Patents

Optik açıdan aktif aminlerin rasemleştirilmesine ilişkin yöntem.

Info

Publication number
TR200102337T2
TR200102337T2 TR2001/02337T TR200102337T TR200102337T2 TR 200102337 T2 TR200102337 T2 TR 200102337T2 TR 2001/02337 T TR2001/02337 T TR 2001/02337T TR 200102337 T TR200102337 T TR 200102337T TR 200102337 T2 TR200102337 T2 TR 200102337T2
Authority
TR
Turkey
Prior art keywords
formula
optically active
racification
cycloalkyl
alkyl
Prior art date
Application number
TR2001/02337T
Other languages
English (en)
Inventor
Riechers Hartmut
Simon Joachim
H�Nn Arthur
Kramer Andreas
Funke Frank
Siegel Wolfgang
N�Bling Christoph
Original Assignee
Basf Aktiengesellschaft
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Basf Aktiengesellschaft filed Critical Basf Aktiengesellschaft
Publication of TR200102337T2 publication Critical patent/TR200102337T2/tr

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C209/00—Preparation of compounds containing amino groups bound to a carbon skeleton
    • C07C209/82—Purification; Separation; Stabilisation; Use of additives
    • C07C209/86—Separation
    • C07C209/88—Separation of optical isomers
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C213/00—Preparation of compounds containing amino and hydroxy, amino and etherified hydroxy or amino and esterified hydroxy groups bound to the same carbon skeleton
    • C07C213/08—Preparation of compounds containing amino and hydroxy, amino and etherified hydroxy or amino and esterified hydroxy groups bound to the same carbon skeleton by reactions not involving the formation of amino groups, hydroxy groups or etherified or esterified hydroxy groups
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C209/00—Preparation of compounds containing amino groups bound to a carbon skeleton
    • C07C209/68—Preparation of compounds containing amino groups bound to a carbon skeleton from amines, by reactions not involving amino groups, e.g. reduction of unsaturated amines, aromatisation, or substitution of the carbon skeleton

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
  • Catalysts (AREA)

Abstract

Formül 1'in içerisinde R ve R 'nin farkli oldugu ve R , R , R 'ün alkil, sikloalkil, arilalkil, aril, heteroaril artiklari ve heretosiklik artiklar anlamina geldigi R 'ün ek olarak hidrojen yerine yazildigi, bunun yaninda artiklarin, alkil, sikloalkil, alkoksi, ariloksi, amino, alkilamino ve dialkilamino grubundan seçilmis ikame maddeleri tasiyabildikleri rasemik aminlerin imal edilmesine yöntemi olup söyle vasiflandirilmistir: ayni zamanda, kendi yerinde optik açidan aktif amin I ve formül II'nin ikincil alkolü ve/veya formül (III)'ün simetrik olmayan ketonu ve formül R NH2'nin amini hidrojen ve bir hidrojenlestirme ve dehidrojenlestirme katalizörü varligina yükseltilmis DEVAMI VAR
TR2001/02337T 1999-02-12 1999-05-10 Optik açıdan aktif aminlerin rasemleştirilmesine ilişkin yöntem. TR200102337T2 (tr)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE19905837A DE19905837A1 (de) 1999-02-12 1999-02-12 Verfahren zur Racemisierung von optisch aktiven Aminen

Publications (1)

Publication Number Publication Date
TR200102337T2 true TR200102337T2 (tr) 2001-12-21

Family

ID=7897266

Family Applications (1)

Application Number Title Priority Date Filing Date
TR2001/02337T TR200102337T2 (tr) 1999-02-12 1999-05-10 Optik açıdan aktif aminlerin rasemleştirilmesine ilişkin yöntem.

Country Status (14)

Country Link
US (2) US6153797A (tr)
EP (1) EP1159252B1 (tr)
JP (1) JP2002539086A (tr)
KR (1) KR100573652B1 (tr)
CN (1) CN1239468C (tr)
AT (1) ATE248140T1 (tr)
AU (1) AU769005B2 (tr)
CA (1) CA2362365C (tr)
DE (2) DE19905837A1 (tr)
ES (1) ES2207226T3 (tr)
NO (1) NO324896B1 (tr)
TR (1) TR200102337T2 (tr)
WO (1) WO2000047545A1 (tr)
ZA (1) ZA200107485B (tr)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE19654391A1 (de) 1996-12-27 1998-07-02 Basf Ag Katalysator zur selektiven Herstellung von Propylen aus Propan
DE19905837A1 (de) * 1999-02-12 2000-08-17 Basf Ag Verfahren zur Racemisierung von optisch aktiven Aminen
CN1173902C (zh) * 1998-11-13 2004-11-03 巴斯福股份公司 光学活性胺的外消旋化
US6060624A (en) * 1999-06-08 2000-05-09 Air Products And Chemicals, Inc. Racemization of optically active alkoxyamines
US8202979B2 (en) * 2002-02-20 2012-06-19 Sirna Therapeutics, Inc. RNA interference mediated inhibition of gene expression using chemically modified short interfering nucleic acid
DE10062729A1 (de) * 2000-12-15 2002-06-20 Basf Ag Verfahren zur Racemisierung von optisch aktiven Aminen
DE102005029095A1 (de) * 2005-06-23 2007-01-18 Basf Ag Verfahren zur kontinuierlichen Herstellung eines Amins
DE102005041388A1 (de) * 2005-09-01 2007-03-08 Zf Lenksysteme Gmbh Rotationspumpe
DE102006000995A1 (de) * 2006-01-05 2007-07-12 Basf Ag Verfahren zur kontinuierlichen Herstellung eines primären aromatischen Amins
CN104152526B (zh) * 2014-08-13 2016-12-07 六安佳诺生化科技有限公司 一种拆分制备光学纯r-1-苯乙胺的方法
CN104152525B (zh) * 2014-08-13 2017-09-29 上海同昌生物医药科技有限公司 一种拆分制备光学纯r‑1‑苯乙胺的方法
CN104131062B (zh) * 2014-08-14 2016-11-23 陈永军 一种拆分制备光学纯s-1-苯乙胺的方法

Family Cites Families (19)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
BE757840A (fr) * 1969-10-23 1971-04-22 Basf Ag Procede de preparation d'amines a partir d'alcools
US4014933A (en) * 1969-10-23 1977-03-29 Basf Aktiengesellschaft Production of amines from alcohols
US3954870A (en) * 1970-05-11 1976-05-04 Sumitomo Chemical Company, Limited Method of racemization of optically active amines
JPS598264B2 (ja) * 1974-06-29 1984-02-23 帝人株式会社 光学活性アミノ化合物のラセミ化方法
DE2851039A1 (de) * 1978-11-25 1980-06-12 Basf Ag Verfahren zur razemisierung von optisch aktiven 1-arylaminen
DE2903589A1 (de) * 1979-01-31 1980-08-14 Basf Ag Verfahren zur razemisierung von optisch aktiven aminen
US4990666A (en) * 1987-02-04 1991-02-05 W. R. Grace & Co.-Conn. Racemization of optically active amino alcohols
DE3903367A1 (de) * 1989-02-04 1990-08-16 Basf Ag Katalysator und verfahren zur hydrierenden aminierung von alkoholen
DE4116367A1 (de) * 1991-05-18 1992-11-19 Basf Ag Verfahren zur herstellung von aminen
JP3230300B2 (ja) * 1992-10-30 2001-11-19 東レ株式会社 光学活性ジアミンのラセミ化法
JP3252579B2 (ja) * 1993-12-28 2002-02-04 東レ株式会社 光学活性１−（ハロゲノフェニル）エチルアミン類のラセミ化法
DE4428004A1 (de) * 1994-08-08 1996-02-15 Basf Ag Verfahren zur Herstellung von Aminen
JP3843474B2 (ja) * 1995-12-07 2006-11-08 住友化学株式会社 光学活性な１−フェニルエチルアミン誘導体のラセミ化方法
DE19606124A1 (de) * 1996-02-20 1997-08-21 Basf Ag Verfahren zur Racemisierung optisch aktiver Amine
DE19629692A1 (de) * 1996-07-23 1998-01-29 Bayer Ag Verfahren zur Herstellung von racemischen Phenethylaminen
DE19905837A1 (de) * 1999-02-12 2000-08-17 Basf Ag Verfahren zur Racemisierung von optisch aktiven Aminen
DE19859775A1 (de) * 1998-12-23 2000-06-29 Basf Ag Verfahren zur Racemisierung von optisch aktiven Aminen
DE19852282A1 (de) * 1998-11-13 2000-05-18 Basf Ag Verfahren zur Racemisierung von optisch aktiven Aminen
DE19905838A1 (de) * 1999-02-12 2000-08-17 Basf Ag Verfahren zur Racemisierung von optisch aktiven Aminen

Also Published As

Publication number Publication date
AU769005B2 (en) 2004-01-15
KR100573652B1 (ko) 2006-04-26
EP1159252A1 (de) 2001-12-05
NO324896B1 (no) 2007-12-27
CN1239468C (zh) 2006-02-01
ATE248140T1 (de) 2003-09-15
CA2362365A1 (en) 2000-08-17
NO20013912L (no) 2001-08-10
DE19905837A1 (de) 2000-08-17
JP2002539086A (ja) 2002-11-19
US6153797A (en) 2000-11-28
ZA200107485B (en) 2002-09-11
WO2000047545A1 (de) 2000-08-17
CA2362365C (en) 2009-07-14
US6049007A (en) 2000-04-11
CN1337934A (zh) 2002-02-27
EP1159252B1 (de) 2003-08-27
AU4140899A (en) 2000-08-29
KR20010102080A (ko) 2001-11-15
DE59906807D1 (de) 2003-10-02
ES2207226T3 (es) 2004-05-16
NO20013912D0 (no) 2001-08-10

Similar Documents

Publication Publication Date Title
TR200102337T2 (tr) Optik açıdan aktif aminlerin rasemleştirilmesine ilişkin yöntem.
PE20010671A1 (es) Indolinonas sustituidas en posicion 6 como inhibidores de tirosina-quinasas
WO2005095409A3 (en) Tetrahydroquinoline derivatives and a process for preparing the same
AR082864A2 (es) Preparacion de compuestos de aminopirimidina
NZ329532A (en) Diazepino-indoles as phosphodiesterase iv inhibitors
ATE383338T1 (de) N-(phenyl(piperidin-2-yl)methyl)benzamid-deriva e,verfahren zu deren herstellung und ihre therapeutische verwendung
MXPA04001014A (es) Novedosos inhibidores de la gama secretasa.
MY141578A (en) Imidazopyrimidine derivatives and triazolopyrimidine derivatives
TW359670B (en) Process for producing quinazolin-4-one derivatives
ATE374779T1 (de) Phosphonium- und imidazoliumsalze und verfahren zu deren herstellung
MXPA02006329A (es) 8-arilquinolinas sustituidas que son inhibidores de fosfodiesterasa-4.
MX9806246A (es) PIPERIDINAS NOVEDOSAS DERIVADAS DE 1-/(PIPERAZIN-1-IL)ARIL-(OXI/AMINO)CARBONIL(4-ARIL-PIPERIDIN A COMO ANTAGONISTAS SELECTIVOS DEL RECEPTOR 5-HT-1D- beta-.
DK164554C (da) 3-vinyl- og 3-ethynyl-beta-carbolinderivater og fremgangsmaade til fremstilling heraf
WO2003078406A8 (en) Amphoteric and cationic fluorescent whitening agents
DK0605033T3 (da) Enzymatisk fremgangsmåde til stereoselektiv fremstilling af en heterobicyklisk alkoholenantiomer
DK0928787T3 (da) Fremgangsmåde til fremstillingen af 3-amino-pyrrolidinderivater
NO20063989L (no) Fremgangsmater for a produsere 3-O-beskyttede morfinoner og 3-O-beskyttede morfinondienol-karboksylater
AU2001228486A1 (en) Method for cleaning off-gas flows
DE50105413D1 (de) Verfahren zur Racemisierung von optisch aktiven Aminen
DE50202381D1 (de) Geschützte tyrosinderivate, verfahren zu deren herstellung und deren verwendung zur herstellung von o-(2- ?18 f]-fluorethyl)-l-tyrosin
MXPA01009615A (es) Procedimiento para la preparacion de acido [s -(r*s*)] -°-[[[1[1- oxo-3 -(4-piperidinil) propil]3 -piperidini] carbonil] amino] -3-piridinil] carbonil] amino] -3-piridinpropanoico, y derivados del mismo.
TR200000117T2 (tr) Alkiloksifuranonun aminli türevlerinin hazırlanmasına yönelik proses.
NO20023513L (no) Anvendelse av et ekstraheringsmiddel som et antiskummiddel ved fremstilling av vannfri maursyre
RU2004114553A (ru) Фотохромные оксазиновые соединения и способы их производства
EA200100155A3 (ru) Новые производные 6-амино или 6-гидразиносульфонил-3-хинолинилфосфоновой кислоты, способ их получения и содержащие их фармацевтические композиции