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TR200002652T2 - The process for the preparation of a tetrapeptide - Google Patents

The process for the preparation of a tetrapeptide

Info

Publication number
TR200002652T2
TR200002652T2 TR2000/02652T TR200002652T TR200002652T2 TR 200002652 T2 TR200002652 T2 TR 200002652T2 TR 2000/02652 T TR2000/02652 T TR 2000/02652T TR 200002652 T TR200002652 T TR 200002652T TR 200002652 T2 TR200002652 T2 TR 200002652T2
Authority
TR
Turkey
Prior art keywords
preparation
tetrapeptide
new
phe
tyr
Prior art date
Application number
TR2000/02652T
Other languages
Turkish (tr)
Inventor
Franzen Henry
Original Assignee
Astrazeneca Ab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Astrazeneca Ab filed Critical Astrazeneca Ab
Publication of TR200002652T2 publication Critical patent/TR200002652T2/en

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K5/00Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/10Tetrapeptides
    • C07K5/1002Tetrapeptides with the first amino acid being neutral
    • C07K5/1016Tetrapeptides with the first amino acid being neutral and aromatic or cycloaliphatic
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K5/00Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/10Tetrapeptides
    • C07K5/1027Tetrapeptides containing heteroatoms different from O, S, or N

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Rheumatology (AREA)
  • Pain & Pain Management (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)

Abstract

Bu bulusta, asagidaki (I) formülüne sahip: bir peptit olan H-Tyr-D-Ala-Phe (pF)-Phe-NH2 yapisindaki tetrapeptitin ya da bunun ilaç sanayiinde kullanilmaya uygun bir tuzunun hazirlanmasina yönelik yeni ve iyilestirilmis bir islemin yani sira,bunun hazirlanmasinda kullanilan yeni ara ürünler anlatilmistir. Yeni islem, büyük ölçekli üretim için uygundur.In this invention, as well as a new and improved process for the preparation of the following formula (I): the tetrapeptide of the peptide H-Tyr-D-Ala-Phe (pF) -Phe-NH2 or a salt thereof suitable for use in the pharmaceutical industry, new intermediate products used in its preparation are described. The new process is suitable for large-scale production.

TR2000/02652T 1998-03-16 1999-03-16 The process for the preparation of a tetrapeptide TR200002652T2 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
SE9800865A SE9800865D0 (en) 1998-03-16 1998-03-16 New Process

Publications (1)

Publication Number Publication Date
TR200002652T2 true TR200002652T2 (en) 2000-11-21

Family

ID=20410566

Family Applications (1)

Application Number Title Priority Date Filing Date
TR2000/02652T TR200002652T2 (en) 1998-03-16 1999-03-16 The process for the preparation of a tetrapeptide

Country Status (19)

Country Link
EP (1) EP1062231A1 (en)
JP (1) JP2002506880A (en)
KR (1) KR20010041888A (en)
CN (1) CN1300293A (en)
AU (1) AU2968899A (en)
BR (1) BR9908765A (en)
CA (1) CA2323678A1 (en)
EE (1) EE200000540A (en)
HU (1) HUP0102877A3 (en)
ID (1) ID26938A (en)
IL (1) IL138244A0 (en)
IS (1) IS5612A (en)
NO (1) NO20004613L (en)
PL (1) PL343277A1 (en)
SE (1) SE9800865D0 (en)
SK (1) SK13442000A3 (en)
TR (1) TR200002652T2 (en)
WO (1) WO1999047548A1 (en)
ZA (1) ZA200004376B (en)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SE9903291D0 (en) * 1999-09-15 1999-09-15 Astra Ab New process
CA2707733C (en) * 2007-12-13 2018-01-02 Cytogel, Llc Advantageous salts of mu-opiate receptor peptides
CN104478993B (en) * 2013-06-20 2017-10-10 重庆理工大学 A kind of non-protein amino acid antibacterial peptide and its application
CN104371002B (en) * 2013-06-20 2017-10-10 重庆理工大学 A kind of non-protein amino acid antibacterial peptide and its application
CN103319568B (en) * 2013-06-20 2015-01-21 重庆理工大学 A kind of non-protein amino acid antimicrobial peptide and its application
CN104783298A (en) * 2015-03-24 2015-07-22 湖州珍贝羊绒制品有限公司 Preparation and application of biological sterilizing composition and nanoemulsion thereof

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SE9503924D0 (en) * 1995-08-18 1995-11-07 Astra Ab Novel opioid peptides
GB9516994D0 (en) * 1995-08-18 1995-10-18 Iaf Biochem Int Solution synthesis of peripheral acting analgestic opioid tetrapeptides

Also Published As

Publication number Publication date
SE9800865D0 (en) 1998-03-16
HUP0102877A2 (en) 2002-01-28
IS5612A (en) 2000-08-30
NO20004613L (en) 2000-10-30
EE200000540A (en) 2002-02-15
SK13442000A3 (en) 2001-04-09
BR9908765A (en) 2000-11-07
ZA200004376B (en) 2001-10-31
JP2002506880A (en) 2002-03-05
WO1999047548A1 (en) 1999-09-23
HUP0102877A3 (en) 2002-02-28
PL343277A1 (en) 2001-08-13
CA2323678A1 (en) 1999-09-23
EP1062231A1 (en) 2000-12-27
CN1300293A (en) 2001-06-20
KR20010041888A (en) 2001-05-25
NO20004613D0 (en) 2000-09-15
IL138244A0 (en) 2001-10-31
ID26938A (en) 2001-02-22
AU2968899A (en) 1999-10-11

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