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TR200000529T2 - Granules without excipients - Google Patents

Granules without excipients

Info

Publication number
TR200000529T2
TR200000529T2 TR2000/00529T TR200000529T TR200000529T2 TR 200000529 T2 TR200000529 T2 TR 200000529T2 TR 2000/00529 T TR2000/00529 T TR 2000/00529T TR 200000529 T TR200000529 T TR 200000529T TR 200000529 T2 TR200000529 T2 TR 200000529T2
Authority
TR
Turkey
Prior art keywords
granules
excipients
prepare
kinds
same time
Prior art date
Application number
TR2000/00529T
Other languages
Turkish (tr)
Inventor
Willem Groenendaal Jan
Original Assignee
Dsm N.V.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Dsm N.V. filed Critical Dsm N.V.
Publication of TR200000529T2 publication Critical patent/TR200000529T2/en

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2095—Tabletting processes; Dosage units made by direct compression of powders or specially processed granules, by eliminating solvents, by melt-extrusion, by injection molding, by 3D printing
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/425—Thiazoles
    • A61K31/429—Thiazoles condensed with heterocyclic ring systems
    • A61K31/43—Compounds containing 4-thia-1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula, e.g. penicillins, penems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1682—Processes
    • A61K9/1688—Processes resulting in pure drug agglomerate optionally containing up to 5% of excipient

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

Içinde eksipiyan olmayan, her türlü farmakolojik formülasyonlara uygun granüller elde edilmistir. Ayni zamanda sözü edilen granülleri tercihen hava jet sistemi olan bir eleme aygiti kullanilarak hazirlamak için bir islem elde edilmistir.Granules suitable for all kinds of pharmacological formulations without excipients were obtained. At the same time, a process has been obtained to prepare said granules using a screening device, preferably an air jet system.

TR2000/00529T 1997-08-29 1998-08-27 Granules without excipients TR200000529T2 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
EP97202651 1997-08-29

Publications (1)

Publication Number Publication Date
TR200000529T2 true TR200000529T2 (en) 2000-08-21

Family

ID=8228682

Family Applications (1)

Application Number Title Priority Date Filing Date
TR2000/00529T TR200000529T2 (en) 1997-08-29 1998-08-27 Granules without excipients

Country Status (5)

Country Link
EP (1) EP1023065A1 (en)
CN (1) CN1268888A (en)
AU (1) AU9540898A (en)
TR (1) TR200000529T2 (en)
WO (1) WO1999011261A1 (en)

Families Citing this family (32)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1209099C (en) † 1999-04-01 2005-07-06 Dsm公司 Agglomerates by crystallisation
EP1238673A4 (en) * 1999-12-14 2005-03-09 Asahi Kasei Pharma Corp Colistin sulfate granules
AT413983B (en) * 2001-04-12 2006-08-15 Sandoz Ag Pharmaceutical composition useful for reducing rapid degradation of the active ingredient comprises clavulanate, in the form of granulated and hydrophobised particles, and an active ingredient
AT412344B (en) * 2001-04-12 2005-01-25 Sandoz Ag Pharmaceutical composition useful for reducing rapid degradation of the active ingredient comprises clavulanate, in the form of granulated and hydrophobised particles, and an active ingredient
EP1474104A2 (en) * 2002-02-01 2004-11-10 Sandoz Ag Demixing-stable granulate
AT500134A1 (en) * 2002-02-01 2005-11-15 Sandoz Ag METHOD FOR PRODUCING A DESMIXING STABLE GRANULATE
AT500131A1 (en) * 2002-02-01 2005-11-15 Sandoz Ag ORGANIC CONNECTIONS
AT500132A1 (en) * 2002-02-06 2005-11-15 Sandoz Ag ORGANIC CONNECTIONS
AT500133A1 (en) * 2002-02-06 2005-11-15 Sandoz Ag METHOD FOR PRODUCING A DESMIXING STABLE GRANULATE
BRPI0408403A (en) * 2003-03-21 2006-03-21 Dsm Ip Assets Bv amoxicillin trihydrate crystalline powder
US7534781B2 (en) 2003-03-21 2009-05-19 Dsm Ip Assets B.V. Crystalline amoxicillin trihydrate powder
EP1786548B1 (en) * 2004-06-30 2014-12-24 DSM Sinochem Pharmaceuticals Netherlands B.V. GRANULES COMPRISING A ß-LACTAM ANTIBIOTIC
KR101355064B1 (en) 2005-03-03 2014-01-24 얀센 파마슈티카 엔.브이. Substituted oxa-diaza-spiro-[5.5]-undecanone derivatives and their use as neurokinin antagonists
NZ556628A (en) 2005-03-08 2009-09-25 Janssen Pharmaceutica Nv Diaza-spiro-[4.4]-nonane derivatives as neurokinin (NK1) antagonists
FI20070521A7 (en) * 2006-11-10 2008-05-11 Atacama Labs Oy Granules, tablets and granulation method
FI20080346A0 (en) * 2008-05-09 2008-05-09 Atacama Labs Oy Process for making a tablet containing additives
FI20080351A0 (en) * 2008-05-09 2008-05-09 Atacama Labs Oy Process for preparing a tablet with low drug content
FI20060990A0 (en) * 2006-11-10 2006-11-10 Iprbox Oy Grains, tablets and granulation method
FI20080353A0 (en) * 2008-05-09 2008-05-09 Atacama Labs Oy Process for preparing a tablet with extra high drug content
FI20080352A0 (en) * 2008-05-09 2008-05-09 Atacama Labs Oy Process for preparing a tablet with high drug content
US8951562B2 (en) * 2006-11-10 2015-02-10 Atacama Labs Oy Method and apparatus or dry granulation
FI20080348A0 (en) * 2008-02-15 2008-05-09 Atacama Labs Oy A novel pharmaceutical formulation
FI20080355A0 (en) * 2008-05-09 2008-05-09 Atacama Labs Oy Process for making tablets containing metformin
WO2008089920A1 (en) 2007-01-26 2008-07-31 Dsm Ip Assets B.V. Process for the manufacture of substituted 2-cyano cinnamic esters
PT2271348T (en) 2008-03-28 2018-04-16 Paratek Pharm Innc FORMULATION OF ORAL TETRACYCIN COMPOUND TABLET
EP2291233B1 (en) 2008-05-09 2019-09-04 Atacama Labs Oy Method for dry granulation
IT1394597B1 (en) 2008-11-05 2012-07-05 Politi DRY GRANULATION IN GAS FLOW.
WO2014033077A1 (en) * 2012-08-28 2014-03-06 Dsm Sinochem Pharmaceuticals Netherlands B.V. Composition comprising an antibiotic and a beta-lactamase inhibitor, wherein at| least one of them is in the form of mini-tablets
BE1021312B1 (en) * 2014-07-30 2015-10-28 Nordic Specialty Pharma Bvba DICLOXACILLIN CAPSULE
CN105832694A (en) * 2016-03-25 2016-08-10 海南汤臣史克生物科技有限公司 Penicillins medicine capsule and preparation method of same
CN106088893B (en) * 2016-07-28 2017-11-28 谭芳 Concealed door closer
WO2021043971A1 (en) 2019-09-06 2021-03-11 Novo Nordisk A/S Method and equipment for fractionation of granules for use in pharmaceutical compositions

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2251250C3 (en) * 1972-10-19 1981-06-25 Hoechst Ag, 6230 Frankfurt Process for the production of high-dose antibiotic tablets
JPS6238A (en) * 1985-03-12 1987-01-06 Sankyo Co Ltd Production of freeze-dried pharmaceutical of mixed vitamin
DE3887179T2 (en) * 1987-03-02 1994-06-16 Brocades Pharma Bv Pharmaceutical composition, pharmaceutical granules and process for their preparation.
DE3927810A1 (en) * 1989-08-23 1991-02-28 Basf Ag RIBOFLAVING RANULATES
GB9009473D0 (en) * 1990-04-27 1990-06-20 Beecham Group Plc Pharmaceutical formulation
GB9109862D0 (en) * 1991-05-08 1991-07-03 Beecham Lab Sa Pharmaceutical formulations
GB9408117D0 (en) * 1994-04-23 1994-06-15 Smithkline Beecham Corp Pharmaceutical formulations
TWI225402B (en) * 1996-03-13 2004-12-21 Biochemie Gmbh Auxiliary-free agglomerates

Also Published As

Publication number Publication date
AU9540898A (en) 1999-03-22
WO1999011261A1 (en) 1999-03-11
CN1268888A (en) 2000-10-04
EP1023065A1 (en) 2000-08-02

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