TNSN08346A1 - DIBENZYLAMINE DERIVATIVES AS CETP INHIBITORS - Google Patents
DIBENZYLAMINE DERIVATIVES AS CETP INHIBITORSInfo
- Publication number
- TNSN08346A1 TNSN08346A1 TNP2008000346A TNSN08346A TNSN08346A1 TN SN08346 A1 TNSN08346 A1 TN SN08346A1 TN P2008000346 A TNP2008000346 A TN P2008000346A TN SN08346 A TNSN08346 A TN SN08346A TN SN08346 A1 TNSN08346 A1 TN SN08346A1
- Authority
- TN
- Tunisia
- Prior art keywords
- cholesterol
- cetp inhibitors
- dibenzylamine
- derivatives
- ldl
- Prior art date
Links
- BWLUMTFWVZZZND-UHFFFAOYSA-N Dibenzylamine Chemical class C=1C=CC=CC=1CNCC1=CC=CC=C1 BWLUMTFWVZZZND-UHFFFAOYSA-N 0.000 title abstract 3
- 239000003354 cholesterol ester transfer protein inhibitor Substances 0.000 title 1
- 108010023302 HDL Cholesterol Proteins 0.000 abstract 2
- 108010028554 LDL Cholesterol Proteins 0.000 abstract 2
- 238000008214 LDL Cholesterol Methods 0.000 abstract 2
- 150000001875 compounds Chemical class 0.000 abstract 2
- 150000002632 lipids Chemical class 0.000 abstract 2
- 230000036470 plasma concentration Effects 0.000 abstract 2
- 150000003626 triacylglycerols Chemical class 0.000 abstract 2
- 201000001320 Atherosclerosis Diseases 0.000 abstract 1
- 208000024172 Cardiovascular disease Diseases 0.000 abstract 1
- 241000124008 Mammalia Species 0.000 abstract 1
- 201000010099 disease Diseases 0.000 abstract 1
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 abstract 1
- 239000008194 pharmaceutical composition Substances 0.000 abstract 1
Landscapes
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Abstract
Des dibenzylamines et dérivés de dibenzylamines, de formule (1), des compositions pharmaceutiques contenant ces composés et l'utilisation de ces composés pour élever les taux plasmatiques de certains lipides, comprenant le cholestérol-liprotéines haute densité, et pour abaisser les taux plasmatiques de certains autres lipides, tels que le cholestérol-LDL et les triglycérides et, en conséquence, pour traiter des maladies qui sont exacerbées par des taux bas de cholestérol-HDL et/ou des taux élevés de cholestérol-LDL et de triglycérides, telles que l'athérosclérose et des maladies cardiovasculaires chez certains mammifères, y compris les êtres humainsDibenzylamines and dibenzylamine derivatives of formula (1), pharmaceutical compositions containing these compounds and the use of these compounds for raising the plasma levels of certain lipids, including high density lipoprotein cholesterol, and for lowering plasma levels of some other lipids, such as LDL-cholesterol and triglycerides and, therefore, to treat diseases that are exacerbated by low levels of HDL-cholesterol and / or elevated levels of LDL-cholesterol and triglycerides, such as atherosclerosis and cardiovascular diseases in some mammals, including humans
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US78148806P | 2006-03-10 | 2006-03-10 | |
| US61929907P | 2007-01-03 | 2007-01-03 | |
| PCT/IB2007/000524 WO2007105049A1 (en) | 2006-03-10 | 2007-02-28 | Dibenzyl amine derivatives as cetp inhibitors |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| TNSN08346A1 true TNSN08346A1 (en) | 2009-12-29 |
Family
ID=59798868
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| TNP2008000346A TNSN08346A1 (en) | 2006-03-10 | 2008-09-09 | DIBENZYLAMINE DERIVATIVES AS CETP INHIBITORS |
Country Status (1)
| Country | Link |
|---|---|
| TN (1) | TNSN08346A1 (en) |
-
2008
- 2008-09-09 TN TNP2008000346A patent/TNSN08346A1/en unknown
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