TNSN06270A1 - Hiv integrase inhibitors - Google Patents
Hiv integrase inhibitorsInfo
- Publication number
- TNSN06270A1 TNSN06270A1 TNP2006000270A TNSN06270A TNSN06270A1 TN SN06270 A1 TNSN06270 A1 TN SN06270A1 TN P2006000270 A TNP2006000270 A TN P2006000270A TN SN06270 A TNSN06270 A TN SN06270A TN SN06270 A1 TNSN06270 A1 TN SN06270A1
- Authority
- TN
- Tunisia
- Prior art keywords
- compounds
- hiv
- inhibitors
- hiv integrase
- aids
- Prior art date
Links
- 229940099797 HIV integrase inhibitor Drugs 0.000 title 1
- 239000003084 hiv integrase inhibitor Substances 0.000 title 1
- 150000001875 compounds Chemical class 0.000 abstract 5
- 208000030507 AIDS Diseases 0.000 abstract 2
- 239000003112 inhibitor Substances 0.000 abstract 2
- 230000002265 prevention Effects 0.000 abstract 2
- 150000003839 salts Chemical class 0.000 abstract 2
- 208000031886 HIV Infections Diseases 0.000 abstract 1
- 108010002459 HIV Integrase Proteins 0.000 abstract 1
- 208000037357 HIV infectious disease Diseases 0.000 abstract 1
- 239000003242 anti bacterial agent Substances 0.000 abstract 1
- 229940088710 antibiotic agent Drugs 0.000 abstract 1
- 239000003443 antiviral agent Substances 0.000 abstract 1
- 208000033519 human immunodeficiency virus infectious disease Diseases 0.000 abstract 1
- 125000002887 hydroxy group Chemical group [H]O* 0.000 abstract 1
- 239000002955 immunomodulating agent Substances 0.000 abstract 1
- 229940121354 immunomodulator Drugs 0.000 abstract 1
- 208000015181 infectious disease Diseases 0.000 abstract 1
- 239000004615 ingredient Substances 0.000 abstract 1
- 229940042443 other antivirals in atc Drugs 0.000 abstract 1
- 239000008194 pharmaceutical composition Substances 0.000 abstract 1
- 230000010076 replication Effects 0.000 abstract 1
- 229960005486 vaccine Drugs 0.000 abstract 1
Landscapes
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Abstract
Hydroxy (tetra- or hexa-)hydronaphthyridine dione compounds of Formula (I) are inhibitors of HIV integrase and inhibitors of HIV replication wherein X1, X2, R4 and R5 are defined herein. The compounds are useful in the prevention and treatment of infection by HIV and in the prevention, delay in the onset, and treatment of AIDS. The compounds are employed against HIV infection and AIDS as compounds per se or in the form of pharmaceutically acceptable salts. The compounds and their salts can be employed as ingredients in pharmaceutical compositions, optionally in combination with other antivirals, immunomodulators, antibiotics or vaccines.
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US63313404P | 2004-12-03 | 2004-12-03 | |
| PCT/US2005/007730 WO2005087767A1 (en) | 2004-03-09 | 2005-03-09 | Hiv integrase inhibitors |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| TNSN06270A1 true TNSN06270A1 (en) | 2007-12-03 |
Family
ID=59810961
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| TNP2006000270A TNSN06270A1 (en) | 2004-12-03 | 2006-09-08 | Hiv integrase inhibitors |
Country Status (1)
| Country | Link |
|---|---|
| TN (1) | TNSN06270A1 (en) |
-
2006
- 2006-09-08 TN TNP2006000270A patent/TNSN06270A1/en unknown
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