TN2015000235A1 - Compositions comprising vortioxetine and donepezil - Google Patents
Compositions comprising vortioxetine and donepezilInfo
- Publication number
- TN2015000235A1 TN2015000235A1 TNP2015000235A TN2015000235A TN2015000235A1 TN 2015000235 A1 TN2015000235 A1 TN 2015000235A1 TN P2015000235 A TNP2015000235 A TN P2015000235A TN 2015000235 A TN2015000235 A TN 2015000235A TN 2015000235 A1 TN2015000235 A1 TN 2015000235A1
- Authority
- TN
- Tunisia
- Prior art keywords
- vortioxetine
- donepezil
- compositions
- treatment
- composition
- Prior art date
Links
- ADEBPBSSDYVVLD-UHFFFAOYSA-N donepezil Chemical compound O=C1C=2C=C(OC)C(OC)=CC=2CC1CC(CC1)CCN1CC1=CC=CC=C1 ADEBPBSSDYVVLD-UHFFFAOYSA-N 0.000 title abstract 4
- 229960003530 donepezil Drugs 0.000 title abstract 2
- 239000000203 mixture Substances 0.000 title abstract 2
- YQNWZWMKLDQSAC-UHFFFAOYSA-N vortioxetine Chemical compound CC1=CC(C)=CC=C1SC1=CC=CC=C1N1CCNCC1 YQNWZWMKLDQSAC-UHFFFAOYSA-N 0.000 title abstract 2
- 229960002263 vortioxetine Drugs 0.000 title abstract 2
- 208000010877 cognitive disease Diseases 0.000 abstract 1
- 239000008194 pharmaceutical composition Substances 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/445—Non condensed piperidines, e.g. piperocaine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
- A61P25/16—Anti-Parkinson drugs
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/24—Antidepressants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2121/00—Preparations for use in therapy
Landscapes
- Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Biomedical Technology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Psychiatry (AREA)
- Psychology (AREA)
- Hospice & Palliative Care (AREA)
- Pain & Pain Management (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nutrition Science (AREA)
- Physiology (AREA)
- Plural Heterocyclic Compounds (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201261736799P | 2012-12-13 | 2012-12-13 | |
| PCT/EP2013/076337 WO2014090929A1 (fr) | 2012-12-13 | 2013-12-12 | Compositions comprenant de la vortioxétine et du donépézil |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| TN2015000235A1 true TN2015000235A1 (en) | 2016-10-03 |
Family
ID=49943326
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| TNP2015000235A TN2015000235A1 (en) | 2012-12-13 | 2015-05-27 | Compositions comprising vortioxetine and donepezil |
Country Status (44)
Families Citing this family (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN105218482B (zh) * | 2014-06-24 | 2018-04-06 | 杭州和泽医药科技有限公司 | 沃替西汀氢溴酸盐β晶型的制备方法 |
| CN104610195B (zh) * | 2015-01-30 | 2017-06-27 | 上虞京新药业有限公司 | 沃替西汀的天冬氨酸盐或其水合物及其制备方法和用途 |
| CN105315184B (zh) * | 2015-06-26 | 2017-03-29 | 上海医药工业研究院 | 一种沃替西汀的制备方法及其中间体 |
| US10493046B2 (en) * | 2015-07-17 | 2019-12-03 | Universite Paris Descartes | 5-hydroxytryptamine 1B receptor-stimulating agent for use as a promoter of satellite cells self-renewal and/or differentiation |
| CN105534933A (zh) * | 2016-01-19 | 2016-05-04 | 美吉斯制药(厦门)有限公司 | 一种沃替西汀口腔崩解片及其制备方法 |
| CN109310691A (zh) | 2016-07-01 | 2019-02-05 | H.隆德贝克有限公司 | 用于快速开始抗抑郁作用的给药方案 |
| JP6801129B2 (ja) * | 2017-03-30 | 2020-12-16 | ランドル リサーチ,エルエルシー | うつ病の治療方法 |
| US10398691B2 (en) | 2017-03-30 | 2019-09-03 | Rundle Research, LLC | Methods of treating depression |
| US20210393621A1 (en) | 2018-10-26 | 2021-12-23 | The Research Foundation For The State University Of New York | Combination serotonin specific reuptake inhibitor and serotonin 1a receptor partial agonist for reducing l-dopa-induced dyskinesia |
Family Cites Families (21)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP0268871A1 (fr) | 1986-10-31 | 1988-06-01 | Sumitomo Pharmaceuticals Company, Limited | Dérivés de quinoléine |
| IT1225462B (it) | 1987-04-03 | 1990-11-14 | Mediolanum Farmaceutici Srl | Sali organici di derivati della fisostigmina |
| KR100195399B1 (ko) | 1987-05-04 | 1999-06-15 | 보니데이비스 | 알쯔하이머 병 치료용 의약 |
| EP0403713A1 (fr) | 1989-06-22 | 1990-12-27 | Merrell Dow Pharmaceuticals Inc. | Inhibiteurs d'acétylcholinestérase |
| US4914102A (en) | 1989-09-28 | 1990-04-03 | Hoechst Roussel Pharmaceuticals, Inc. | N-aminocarbamates related to physostigmine, pharmacentical compositions and use |
| TW200462B (fr) | 1990-09-27 | 1993-02-21 | Hoechst Roussel Pharma | |
| US5246947A (en) | 1991-09-23 | 1993-09-21 | Hoechst-Roussel Pharmaceuticals Incorporated | Substituted pyridinylamino-1,2-benzisothiazoles and their use for treating depression |
| US5231093A (en) | 1991-10-01 | 1993-07-27 | Hoechst-Roussel Pharmaceuticals Incorporated | Carbamate derivatives of 4-amino-3-isoxazolidinones, 3-amino-1-hydroxypyrrolidin-2-ones and 1-amino-1-cyclopropanecarboxylic acid analogs |
| ES2042384B1 (es) | 1991-12-26 | 1994-06-01 | Boehringer Ingelheim Espana | Procedimiento para obtener derivados bis-piridinicos. |
| SE9302080D0 (sv) | 1993-06-16 | 1993-06-16 | Ab Astra | New compounds |
| BR9708655A (pt) | 1996-04-12 | 1999-08-03 | Hoechst Marion Roussel Inc | Derivados de isatina como inibidores de acetilcolinesterase e analgésicos |
| UA81749C2 (uk) | 2001-10-04 | 2008-02-11 | Х. Луннбек А/С | Фенілпіперазинові похідні як інгібітори зворотного захоплення серотоніну |
| EP1491531B1 (fr) | 2002-03-29 | 2007-12-26 | Eisai R&D Management Co., Ltd. | Derive de (1-indanone)-(1,2,3,6-tetrahydropyridine) |
| ES2314200T3 (es) * | 2002-05-31 | 2009-03-16 | H. Lundbeck A/S | Una combinacion de un antagonista de nmda e inhibidores de esterasa de acetilcolina par ael tratamiento de la enfermedad de alzheimer. |
| US20060135403A1 (en) * | 2002-12-24 | 2006-06-22 | Francine Gervais | Therapeutic formulations for the treatment of beta-amyloid related diseases |
| CN101460156B (zh) * | 2006-05-08 | 2011-06-08 | 帝国制药株式会社 | 抗痴呆药的经皮吸收制剂 |
| JP2009539850A (ja) * | 2006-06-09 | 2009-11-19 | ワイス | 認知機能を増強する方法 |
| AR061481A1 (es) * | 2006-06-16 | 2008-08-27 | Lundbeck & Co As H | Compuestos con actividad combinada sobre sert, 5-ht3 y 5-ht1a |
| WO2009005519A1 (fr) * | 2007-06-29 | 2009-01-08 | Accera, Inc. | Combinaisons de triglycérides à chaîne moyenne et d'agents thérapeutiques pour le traitement et la prévention de la maladie d'alzheimer et d'autres maladies résultant d'un métabolisme neuronal réduit |
| TW200932233A (en) * | 2007-11-13 | 2009-08-01 | Lundbeck & Co As H | Therapeutic uses of compounds having combined SERT, 5-HT3 and 5-HT1a activity |
| TW201033181A (en) | 2009-02-17 | 2010-09-16 | Lundbeck & Co As H | Purification of 1-[2-(2,4-dimethylphenylsulfanyl)phenyl]piperazine |
-
2013
- 2013-12-12 JP JP2015547020A patent/JP6257641B2/ja active Active
- 2013-12-12 HR HRP20180333TT patent/HRP20180333T1/hr unknown
- 2013-12-12 MY MYPI2015001479A patent/MY171802A/en unknown
- 2013-12-12 ES ES13818702.6T patent/ES2663680T3/es active Active
- 2013-12-12 AR ARP130104651A patent/AR093939A1/es not_active Application Discontinuation
- 2013-12-12 EP EP13818702.6A patent/EP2931276B1/fr active Active
- 2013-12-12 MA MA38253A patent/MA38253B1/fr unknown
- 2013-12-12 WO PCT/EP2013/076337 patent/WO2014090929A1/fr not_active Ceased
- 2013-12-12 CA CA2893468A patent/CA2893468C/fr active Active
- 2013-12-12 UA UAA201506381A patent/UA114016C2/uk unknown
- 2013-12-12 LT LTEP13818702.6T patent/LT2931276T/lt unknown
- 2013-12-12 RS RS20180285A patent/RS56949B1/sr unknown
- 2013-12-12 PT PT138187026T patent/PT2931276T/pt unknown
- 2013-12-12 HU HUE13818702A patent/HUE036280T2/hu unknown
- 2013-12-12 AU AU2013357308A patent/AU2013357308B2/en not_active Ceased
- 2013-12-12 SI SI201330970T patent/SI2931276T1/en unknown
- 2013-12-12 BR BR112015013675-3A patent/BR112015013675B1/pt not_active IP Right Cessation
- 2013-12-12 US US14/649,087 patent/US9211288B2/en active Active
- 2013-12-12 MX MX2015007269A patent/MX362886B/es active IP Right Grant
- 2013-12-12 KR KR1020157015715A patent/KR102171152B1/ko not_active Expired - Fee Related
- 2013-12-12 GE GEAP201313850A patent/GEP201706739B/en unknown
- 2013-12-12 AP AP2015008498A patent/AP2015008498A0/xx unknown
- 2013-12-12 PL PL13818702T patent/PL2931276T3/pl unknown
- 2013-12-12 CN CN201380065034.2A patent/CN104853755B/zh active Active
- 2013-12-12 DK DK13818702.6T patent/DK2931276T3/en active
- 2013-12-12 NZ NZ708595A patent/NZ708595A/en not_active IP Right Cessation
- 2013-12-12 ME MEP-2018-66A patent/ME03029B/fr unknown
- 2013-12-12 PE PE2015000879A patent/PE20151026A1/es active IP Right Grant
- 2013-12-12 SG SG11201504483YA patent/SG11201504483YA/en unknown
- 2013-12-12 SM SM20180135T patent/SMT201800135T1/it unknown
- 2013-12-12 RU RU2015122256A patent/RU2635528C2/ru active
- 2013-12-12 EA EA201590932A patent/EA028300B1/ru not_active IP Right Cessation
-
2014
- 2014-03-05 NO NO14709546A patent/NO2970700T3/no unknown
-
2015
- 2015-05-27 TN TNP2015000235A patent/TN2015000235A1/fr unknown
- 2015-06-03 DO DO2015000133A patent/DOP2015000133A/es unknown
- 2015-06-03 IL IL239192A patent/IL239192B/en active IP Right Grant
- 2015-06-08 PH PH12015501302A patent/PH12015501302A1/en unknown
- 2015-06-08 GT GT201500143A patent/GT201500143A/es unknown
- 2015-06-09 EC ECIEPI201523182A patent/ECSP15023182A/es unknown
- 2015-06-09 CR CR20150303A patent/CR20150303A/es unknown
- 2015-06-09 NI NI201500078A patent/NI201500078A/es unknown
- 2015-06-10 CL CL2015001615A patent/CL2015001615A1/es unknown
- 2015-06-12 ZA ZA2015/04274A patent/ZA201504274B/en unknown
-
2018
- 2018-03-27 CY CY20181100347T patent/CY1120098T1/el unknown
-
2022
- 2022-05-19 AR ARP220101337A patent/AR125920A2/es not_active Application Discontinuation
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