TN2014000288A1 - Pde9 inhibitors with imidazo triazinone backbone - Google Patents
Pde9 inhibitors with imidazo triazinone backboneInfo
- Publication number
- TN2014000288A1 TN2014000288A1 TNP2014000288A TN2014000288A TN2014000288A1 TN 2014000288 A1 TN2014000288 A1 TN 2014000288A1 TN P2014000288 A TNP2014000288 A TN P2014000288A TN 2014000288 A TN2014000288 A TN 2014000288A TN 2014000288 A1 TN2014000288 A1 TN 2014000288A1
- Authority
- TN
- Tunisia
- Prior art keywords
- compound
- formula
- effective amount
- therapeutically effective
- present
- Prior art date
Links
- 229940076380 PDE9 inhibitor Drugs 0.000 title 1
- IJYHVZICHKCLMQ-UHFFFAOYSA-N imidazo[4,5-d]triazin-4-one Chemical group O=C1N=NN=C2N=CN=C12 IJYHVZICHKCLMQ-UHFFFAOYSA-N 0.000 title 1
- 150000001875 compounds Chemical class 0.000 abstract 6
- 238000000034 method Methods 0.000 abstract 3
- 101100407341 Drosophila melanogaster Pde9 gene Proteins 0.000 abstract 1
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 abstract 1
- 239000003937 drug carrier Substances 0.000 abstract 1
- 239000002532 enzyme inhibitor Substances 0.000 abstract 1
- 208000015122 neurodegenerative disease Diseases 0.000 abstract 1
- 239000008194 pharmaceutical composition Substances 0.000 abstract 1
Landscapes
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Abstract
This invention is directed to compounds, which are PDE9 enzyme inhibitors. The invention provides a pharmaceutical composition comprising a therapeutically effective amount of a compound of the invention and a pharmaceutically acceptable carrier. The present invention aise provides processes for the preparation of the compounds of formula (1). The present invention further provides a method of treating a subject suffering from a neurodegenerative disorder comprising administering to the subject a therapeutically effective amount of a compound of formula (1). The present invention further provides a compound of formula(!) for use in a method of treating a subject suffering from a psychiatrie disorder comprising administering to the subject a therapeutically effective amount of a compound of formula (1).
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN2012080208 | 2012-08-16 | ||
| PCT/EP2013/051451 WO2013110768A1 (en) | 2012-01-26 | 2013-01-25 | Pde9 inhibitors with imidazo triazinone backbone |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| TN2014000288A1 true TN2014000288A1 (en) | 2015-12-21 |
Family
ID=55447208
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| TNP2014000288A TN2014000288A1 (en) | 2012-08-16 | 2014-07-02 | Pde9 inhibitors with imidazo triazinone backbone |
Country Status (1)
| Country | Link |
|---|---|
| TN (1) | TN2014000288A1 (en) |
-
2014
- 2014-07-02 TN TNP2014000288A patent/TN2014000288A1/en unknown
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| PH12014501695A1 (en) | Pde9 inhibitors with imidazo triazinone backbone | |
| TN2015000100A1 (en) | Pde9i with imidazo pyrazinone backbone | |
| MY152949A (en) | Novel phenylimidazole derivatives as pde10a enzyme inhibitors | |
| MY158202A (en) | 2-arylimidazole derivatives as pde10a anzyme inhibitors | |
| JO3089B1 (en) | Imidazole derivatives as inhibitors of PDE10A enzymes | |
| MX2014005928A (en) | Heterocyclic inhibitors of glutaminase. | |
| TN2012000271A1 (en) | Heteroaromatic phenylimidazole derivatives as pde10a enzyme inhibitors | |
| EA201290517A1 (en) | Heteroaromatic aryltriasol derivatives produced as enzyme inhibitors PDE10A | |
| MX2013012588A (en) | Kinase inhibitors. | |
| UA102693C2 (en) | Phenylimidazole derivatives as pde10a enzyme inhibitors | |
| PH12014502757B1 (en) | Dihydronaphthyridines and related compounds useful as kinase inhibitors for the treatment of proliferative diseases | |
| NZ703940A (en) | Pharmaceutical combinations comprising a b-raf inhibitor, an egfr inhibitor and optionally a pi3k-alpha inhibitor | |
| TN2014000288A1 (en) | Pde9 inhibitors with imidazo triazinone backbone | |
| MY165216A (en) | Quinoline derivatives as pde10a enzyme inhibitors | |
| MX336915B (en) | Imidazole derivatives as pde10a enzyme inhibitors. | |
| TN2013000200A1 (en) | Imidazole derivatives as pde 10a enzyme inhibitors |