TN2013000221A1 - Compounds and their use - Google Patents
Compounds and their useInfo
- Publication number
- TN2013000221A1 TN2013000221A1 TNP2013000221A TN2013000221A TN2013000221A1 TN 2013000221 A1 TN2013000221 A1 TN 2013000221A1 TN P2013000221 A TNP2013000221 A TN P2013000221A TN 2013000221 A TN2013000221 A TN 2013000221A TN 2013000221 A1 TN2013000221 A1 TN 2013000221A1
- Authority
- TN
- Tunisia
- Prior art keywords
- compounds
- formula
- lactamases
- restore
- inhibitors
- Prior art date
Links
- 150000001875 compounds Chemical class 0.000 title abstract 6
- 108020004256 Beta-lactamase Proteins 0.000 abstract 2
- 102000006635 beta-lactamase Human genes 0.000 abstract 2
- 239000003242 anti bacterial agent Substances 0.000 abstract 1
- 229940088710 antibiotic agent Drugs 0.000 abstract 1
- 239000003782 beta lactam antibiotic agent Substances 0.000 abstract 1
- 239000003781 beta lactamase inhibitor Substances 0.000 abstract 1
- 229940126813 beta-lactamase inhibitor Drugs 0.000 abstract 1
- 230000003115 biocidal effect Effects 0.000 abstract 1
- 108010068385 carbapenemase Proteins 0.000 abstract 1
- 238000002405 diagnostic procedure Methods 0.000 abstract 1
- 230000000694 effects Effects 0.000 abstract 1
- 208000015181 infectious disease Diseases 0.000 abstract 1
- 239000003112 inhibitor Substances 0.000 abstract 1
- 239000008194 pharmaceutical composition Substances 0.000 abstract 1
- 230000003389 potentiating effect Effects 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
- 239000012453 solvate Substances 0.000 abstract 1
- 238000001228 spectrum Methods 0.000 abstract 1
- 239000002132 β-lactam antibiotic Substances 0.000 abstract 1
- 229940124586 β-lactam antibiotics Drugs 0.000 abstract 1
Landscapes
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Abstract
Described herein are compounds and their use in the treatment of infections. The compound of formula (I), their derivatives, analogs, tautomeric forms, stereoisomers, polymorphs, solvates, pharmaceutically acceptable salts and pharmaceutical compositions described herein are also useful as β -lactamase inhibitors, which restore or enhance the antibiotic spectrum of a suitable antibiotic agent. The compounds of formula (I) act as inhibitors of β-lactamases. These compounds restore/potentiate the activities of β-lactam antibiotics against carbapenemases. These compounds find use in diagnostic method for detecting β-lactamases. Formula (I)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| IN3555CH2010 | 2010-11-25 | ||
| PCT/IN2011/000813 WO2012070071A1 (en) | 2010-11-25 | 2011-11-25 | Compounds and their use |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| TN2013000221A1 true TN2013000221A1 (en) | 2014-11-10 |
Family
ID=54359559
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| TNP2013000221A TN2013000221A1 (en) | 2010-11-25 | 2013-05-24 | Compounds and their use |
Country Status (1)
| Country | Link |
|---|---|
| TN (1) | TN2013000221A1 (en) |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN110840897A (en) * | 2019-11-28 | 2020-02-28 | 西华大学 | Metal β -lactamase inhibitor |
-
2013
- 2013-05-24 TN TNP2013000221A patent/TN2013000221A1/en unknown
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN110840897A (en) * | 2019-11-28 | 2020-02-28 | 西华大学 | Metal β -lactamase inhibitor |
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