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TN2013000202A1 - Spiro-oxindole mdm2 antagonists - Google Patents

Spiro-oxindole mdm2 antagonists

Info

Publication number
TN2013000202A1
TN2013000202A1 TNP2013000202A TN2013000202A TN2013000202A1 TN 2013000202 A1 TN2013000202 A1 TN 2013000202A1 TN P2013000202 A TNP2013000202 A TN P2013000202A TN 2013000202 A TN2013000202 A TN 2013000202A TN 2013000202 A1 TN2013000202 A1 TN 2013000202A1
Authority
TN
Tunisia
Prior art keywords
spiro
mdm2 antagonists
oxindole mdm2
antagonists
oxindole
Prior art date
Application number
TNP2013000202A
Other languages
French (fr)
Inventor
Yujun Zhao
Wei Sun
Sanjeev Kumar
Lance Leopold
Cedric Barriere
Jean-Christophe Carry
Kwame Amaning
Ming Guo
Laurent Debussche
Original Assignee
Univ Michigan
Ascenta Licensing Corp 3 Sanofi
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from PCT/US2011/060300 external-priority patent/WO2012065022A2/en
Application filed by Univ Michigan, Ascenta Licensing Corp 3 Sanofi filed Critical Univ Michigan
Publication of TN2013000202A1 publication Critical patent/TN2013000202A1/en

Links

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  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

Provided herein are compounds, compositions, and methods in the field of medicinal chemistry. The compounds and compositions provided herein relate to spiro-oxindoles which function as antagonists of the interaction between p53 and MDM2, and their use as therapeutics for the treatment of cancer and other diseases.
TNP2013000202A 2011-11-11 2013-05-08 Spiro-oxindole mdm2 antagonists TN2013000202A1 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
PCT/US2011/060300 WO2012065022A2 (en) 2010-11-12 2011-11-11 Spiro-oxindole mdm2 antagonists

Publications (1)

Publication Number Publication Date
TN2013000202A1 true TN2013000202A1 (en) 2014-11-10

Family

ID=54360702

Family Applications (1)

Application Number Title Priority Date Filing Date
TNP2013000202A TN2013000202A1 (en) 2011-11-11 2013-05-08 Spiro-oxindole mdm2 antagonists

Country Status (1)

Country Link
TN (1) TN2013000202A1 (en)

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