TN2010000621A1 - Human cytomegalovirus neutralizing antibodies and use thereof - Google Patents
Human cytomegalovirus neutralizing antibodies and use thereofInfo
- Publication number
- TN2010000621A1 TN2010000621A1 TNP2010000621A TN2010000621A TN2010000621A1 TN 2010000621 A1 TN2010000621 A1 TN 2010000621A1 TN P2010000621 A TNP2010000621 A TN P2010000621A TN 2010000621 A TN2010000621 A TN 2010000621A TN 2010000621 A1 TN2010000621 A1 TN 2010000621A1
- Authority
- TN
- Tunisia
- Prior art keywords
- antibodies
- antibody fragments
- neutralizing antibodies
- human cytomegalovirus
- relates
- Prior art date
Links
- 230000003472 neutralizing effect Effects 0.000 title abstract 3
- 241000701024 Human betaherpesvirus 5 Species 0.000 title 1
- 102000008394 Immunoglobulin Fragments Human genes 0.000 abstract 4
- 108010021625 Immunoglobulin Fragments Proteins 0.000 abstract 4
- 210000003719 b-lymphocyte Anatomy 0.000 abstract 1
- 238000003745 diagnosis Methods 0.000 abstract 1
- 201000010099 disease Diseases 0.000 abstract 1
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 abstract 1
- 238000000034 method Methods 0.000 abstract 1
- 230000002265 prevention Effects 0.000 abstract 1
- 108090000623 proteins and genes Proteins 0.000 abstract 1
- 238000012216 screening Methods 0.000 abstract 1
- 238000002560 therapeutic procedure Methods 0.000 abstract 1
Landscapes
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Peptides Or Proteins (AREA)
Abstract
The invention relates to neutralizing antibodies, and antibody fragments thereof, having high potency in neutralizing hCMV, wherein said antibodies and antibody fragments are specific for one, or a combination of two or more, hCMV gene UL products. The invention also relates to immortalized B cells that produce, and to epitopes that bind to, such antibodies and antibody fragments. In addition, the invention relates to the use of the antibodies, antibody fragments, and epitopes in screening methods as well as in the diagnosis, prevention, and therapy of disease.
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| PCT/IB2009/006641 WO2010007533A2 (en) | 2008-07-16 | 2009-07-15 | Human cytomegalovirus neutralizing antibodies and use thereof |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| TN2010000621A1 true TN2010000621A1 (en) | 2012-05-24 |
Family
ID=55024691
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| TNP2010000621A TN2010000621A1 (en) | 2009-07-15 | 2010-12-29 | Human cytomegalovirus neutralizing antibodies and use thereof |
Country Status (1)
| Country | Link |
|---|---|
| TN (1) | TN2010000621A1 (en) |
-
2010
- 2010-12-29 TN TNP2010000621A patent/TN2010000621A1/en unknown
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