TN2010000519A1 - Fused nitrogen containing heterocycles and compositions thereof as kinase inhibitors - Google Patents
Fused nitrogen containing heterocycles and compositions thereof as kinase inhibitorsInfo
- Publication number
- TN2010000519A1 TN2010000519A1 TNP2010000519A TN2010000519A TN2010000519A1 TN 2010000519 A1 TN2010000519 A1 TN 2010000519A1 TN P2010000519 A TNP2010000519 A TN P2010000519A TN 2010000519 A TN2010000519 A TN 2010000519A TN 2010000519 A1 TN2010000519 A1 TN 2010000519A1
- Authority
- TN
- Tunisia
- Prior art keywords
- compositions
- kinase inhibitors
- nitrogen containing
- containing heterocycles
- compounds
- Prior art date
Links
- 229940043355 kinase inhibitor Drugs 0.000 title 1
- 239000000203 mixture Substances 0.000 title 1
- 239000003757 phosphotransferase inhibitor Substances 0.000 title 1
- 150000001875 compounds Chemical class 0.000 abstract 3
- 101000916644 Homo sapiens Macrophage colony-stimulating factor 1 receptor Proteins 0.000 abstract 2
- 102100028198 Macrophage colony-stimulating factor 1 receptor Human genes 0.000 abstract 2
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 abstract 2
- 102100034134 Activin receptor type-1B Human genes 0.000 abstract 1
- 101000799189 Homo sapiens Activin receptor type-1B Proteins 0.000 abstract 1
- 101000692455 Homo sapiens Platelet-derived growth factor receptor beta Proteins 0.000 abstract 1
- 101000932478 Homo sapiens Receptor-type tyrosine-protein kinase FLT3 Proteins 0.000 abstract 1
- 101000997832 Homo sapiens Tyrosine-protein kinase JAK2 Proteins 0.000 abstract 1
- 101000934996 Homo sapiens Tyrosine-protein kinase JAK3 Proteins 0.000 abstract 1
- -1 IGF-1R Proteins 0.000 abstract 1
- 101150028321 Lck gene Proteins 0.000 abstract 1
- 101150111783 NTRK1 gene Proteins 0.000 abstract 1
- 101150117329 NTRK3 gene Proteins 0.000 abstract 1
- 101150056950 Ntrk2 gene Proteins 0.000 abstract 1
- 108091000080 Phosphotransferase Proteins 0.000 abstract 1
- 102100026547 Platelet-derived growth factor receptor beta Human genes 0.000 abstract 1
- 102000016971 Proto-Oncogene Proteins c-kit Human genes 0.000 abstract 1
- 108010014608 Proto-Oncogene Proteins c-kit Proteins 0.000 abstract 1
- 102100020718 Receptor-type tyrosine-protein kinase FLT3 Human genes 0.000 abstract 1
- 102100033444 Tyrosine-protein kinase JAK2 Human genes 0.000 abstract 1
- 102100025387 Tyrosine-protein kinase JAK3 Human genes 0.000 abstract 1
- 230000002159 abnormal effect Effects 0.000 abstract 1
- 239000005441 aurora Substances 0.000 abstract 1
- 230000002074 deregulated effect Effects 0.000 abstract 1
- 201000010099 disease Diseases 0.000 abstract 1
- 208000035475 disorder Diseases 0.000 abstract 1
- 230000000694 effects Effects 0.000 abstract 1
- 239000008194 pharmaceutical composition Substances 0.000 abstract 1
- 102000020233 phosphotransferase Human genes 0.000 abstract 1
Landscapes
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Abstract
The invention provides compounds, pharmaceutical compositions comprising such compounds and methods of using such compounds to treat or prevent diseases or disorders associated with abnormal or deregulated kinase activity, particularly Ros, KDR, FMS, C-FMS, FLT3, c-Kit, JAK2, JAK3, Aurora, PDGFR, Lck, TrkA, TrkB, TrkC, IGF-1R, ALK4, ALK5 and ALK or combinations thereof.
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| PCT/US2009/043073 WO2009140128A2 (en) | 2008-05-13 | 2009-05-07 | Compounds and compositions as kinase inhibitors |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| TN2010000519A1 true TN2010000519A1 (en) | 2012-05-24 |
Family
ID=55024614
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| TNP2010000519A TN2010000519A1 (en) | 2009-05-07 | 2010-11-05 | Fused nitrogen containing heterocycles and compositions thereof as kinase inhibitors |
Country Status (1)
| Country | Link |
|---|---|
| TN (1) | TN2010000519A1 (en) |
-
2010
- 2010-11-05 TN TNP2010000519A patent/TN2010000519A1/en unknown
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