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TN2010000466A1 - Acylamino subsitutued fused cyclopentanecarboxylic acid derivatives and their use as pharmaceuticals - Google Patents

Acylamino subsitutued fused cyclopentanecarboxylic acid derivatives and their use as pharmaceuticals

Info

Publication number
TN2010000466A1
TN2010000466A1 TNP2010000466A TN2010000466A TN2010000466A1 TN 2010000466 A1 TN2010000466 A1 TN 2010000466A1 TN P2010000466 A TNP2010000466 A TN P2010000466A TN 2010000466 A TN2010000466 A TN 2010000466A TN 2010000466 A1 TN2010000466 A1 TN 2010000466A1
Authority
TN
Tunisia
Prior art keywords
subsitutued
acylamino
pharmaceuticals
acid derivatives
cyclopentanecarboxylic acid
Prior art date
Application number
TNP2010000466A
Other languages
French (fr)
Inventor
Matthias Schaefer
Josef Pernerstorfer
Dieter Kadereit
Hartmut Strobel
Werngard Czechtizky
L Charlie Chen
Alena Safarova
Aleksandra Weichsel
Marcel Patek
Original Assignee
Sanofi Aventis
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from PCT/EP2009/002917 external-priority patent/WO2009135590A1/en
Application filed by Sanofi Aventis filed Critical Sanofi Aventis
Publication of TN2010000466A1 publication Critical patent/TN2010000466A1/en

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  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)

Abstract

The present invention relates to compounds of the formula (I), wherein A, Y, Z, R3 to R6, R20 to R22 and R50 have the meanings indicated in the claims, which are valuable pharmaceutical active compounds. Specifically, they are inhibitors of the endothelial differentiation gene receptor 2 (Edg-2, EDG2), which is activated by lysophosphatidic acid (LPA) and is also termed as LPA1 receptor, and are useful for the treatment of diseases such as atherosclerosis, myocardial infarction and heart failure, for example. The invention furthermore relates to processes for the preparation of the compounds of the formula (I), their use and pharmaceutical compositions comprising them.
TNP2010000466A 2009-04-22 2010-10-14 Acylamino subsitutued fused cyclopentanecarboxylic acid derivatives and their use as pharmaceuticals TN2010000466A1 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
PCT/EP2009/002917 WO2009135590A1 (en) 2008-05-05 2009-04-22 Acylamino-substituted fused cyclopentanecarboxylic acid derivatives and their use as pharmaceuticals

Publications (1)

Publication Number Publication Date
TN2010000466A1 true TN2010000466A1 (en) 2012-05-24

Family

ID=55024578

Family Applications (1)

Application Number Title Priority Date Filing Date
TNP2010000466A TN2010000466A1 (en) 2009-04-22 2010-10-14 Acylamino subsitutued fused cyclopentanecarboxylic acid derivatives and their use as pharmaceuticals

Country Status (1)

Country Link
TN (1) TN2010000466A1 (en)

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