TN2010000337A1 - Tricyclic compounds having corticotropin-releasing factor antagonistic activity and pharmaceutical compositions containing them - Google Patents
Tricyclic compounds having corticotropin-releasing factor antagonistic activity and pharmaceutical compositions containing themInfo
- Publication number
- TN2010000337A1 TN2010000337A1 TNP2010000337A TN2010000337A TN2010000337A1 TN 2010000337 A1 TN2010000337 A1 TN 2010000337A1 TN P2010000337 A TNP2010000337 A TN P2010000337A TN 2010000337 A TN2010000337 A TN 2010000337A TN 2010000337 A1 TN2010000337 A1 TN 2010000337A1
- Authority
- TN
- Tunisia
- Prior art keywords
- antagonistic activity
- corticotropin
- pharmaceutical compositions
- compositions containing
- releasing factor
- Prior art date
Links
- 230000003042 antagnostic effect Effects 0.000 title abstract 2
- 150000001875 compounds Chemical class 0.000 title abstract 2
- 102000012289 Corticotropin-Releasing Hormone Human genes 0.000 title 1
- 108010022152 Corticotropin-Releasing Hormone Proteins 0.000 title 1
- 239000000055 Corticotropin-Releasing Hormone Substances 0.000 title 1
- 239000008194 pharmaceutical composition Substances 0.000 title 1
- IJGRMHOSHXDMSA-UHFFFAOYSA-N nitrogen Substances N#N IJGRMHOSHXDMSA-UHFFFAOYSA-N 0.000 abstract 3
- 125000001183 hydrocarbyl group Chemical group 0.000 abstract 2
- 229910052757 nitrogen Inorganic materials 0.000 abstract 2
- 108010056643 Corticotropin-Releasing Hormone Receptors Proteins 0.000 abstract 1
- 229910052799 carbon Inorganic materials 0.000 abstract 1
- 150000001721 carbon Chemical class 0.000 abstract 1
- 229910052739 hydrogen Inorganic materials 0.000 abstract 1
- 239000001257 hydrogen Substances 0.000 abstract 1
- 150000002431 hydrogen Chemical group 0.000 abstract 1
- QJGQUHMNIGDVPM-UHFFFAOYSA-N nitrogen group Chemical group [N] QJGQUHMNIGDVPM-UHFFFAOYSA-N 0.000 abstract 1
- 229940002612 prodrug Drugs 0.000 abstract 1
- 239000000651 prodrug Substances 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
Landscapes
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Abstract
There is provided a compound of the formula (l') : wherein X is a nitrogen or CRx, Rx is a hydrogen, etc., R1 is an optionally substituted hydrocarbon group, etc., R2 is an optionally substituted hydrocarbon group, etc., ring A is 5- to -8-membered heterocyclic ring, etc., and each of y1,. y2 and y3 is an optionally substituted carbon or a nitrogen, etc.; or 'a salt thereof or a prodrug thereof., which have CRF receptor antagonistic activity and use thereof
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| PCT/JP2009/051299 WO2009093747A1 (en) | 2008-01-22 | 2009-01-21 | Tricyclic compounds having corticotropin-releasing factor antagonistic activity and pharmaceutical compositions containing them |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| TN2010000337A1 true TN2010000337A1 (en) | 2011-12-29 |
Family
ID=55024467
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| TNP2010000337A TN2010000337A1 (en) | 2009-01-21 | 2010-07-19 | Tricyclic compounds having corticotropin-releasing factor antagonistic activity and pharmaceutical compositions containing them |
Country Status (1)
| Country | Link |
|---|---|
| TN (1) | TN2010000337A1 (en) |
-
2010
- 2010-07-19 TN TNP2010000337A patent/TN2010000337A1/en unknown
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