[go: up one dir, main page]

TN2009000371A1 - Composition pharmaceutique - Google Patents

Composition pharmaceutique

Info

Publication number
TN2009000371A1
TN2009000371A1 TNP2009000371A TN2009000371A TN2009000371A1 TN 2009000371 A1 TN2009000371 A1 TN 2009000371A1 TN P2009000371 A TNP2009000371 A TN P2009000371A TN 2009000371 A TN2009000371 A TN 2009000371A TN 2009000371 A1 TN2009000371 A1 TN 2009000371A1
Authority
TN
Tunisia
Prior art keywords
pharmaceutical composition
sorbitol
tablet
angiotensin
surface area
Prior art date
Application number
TNP2009000371A
Other languages
English (en)
Inventor
Ruediger Thomas
Frieder Maerz
Original Assignee
Boehringer Ingelheim Int
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=38179677&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=TN2009000371(A1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Boehringer Ingelheim Int filed Critical Boehringer Ingelheim Int
Publication of TN2009000371A1 publication Critical patent/TN2009000371A1/fr

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2072—Pills, tablets, discs, rods characterised by shape, structure or size; Tablets with holes, special break lines or identification marks; Partially coated tablets; Disintegrating flat shaped forms
    • A61K9/2086—Layered tablets, e.g. bilayer tablets; Tablets of the type inert core-active coat
    • A61K9/209—Layered tablets, e.g. bilayer tablets; Tablets of the type inert core-active coat containing drug in at least two layers or in the core and in at least one outer layer
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/4164—1,3-Diazoles
    • A61K31/4184—1,3-Diazoles condensed with carbocyclic rings, e.g. benzimidazoles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/26—Carbohydrates, e.g. sugar alcohols, amino sugars, nucleic acids, mono-, di- or oligo-saccharides; Derivatives thereof, e.g. polysorbates, sorbitan fatty acid esters or glycyrrhizin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2009—Inorganic compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2013—Organic compounds, e.g. phospholipids, fats
    • A61K9/2018—Sugars, or sugar alcohols, e.g. lactose, mannitol; Derivatives thereof, e.g. polysorbates
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00—Drugs for disorders of the urinary system
    • A61P13/12—Drugs for disorders of the urinary system of the kidneys
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/04—Anorexiants; Antiobesity agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/06—Antihyperlipidemics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/04—Inotropic agents, i.e. stimulants of cardiac contraction; Drugs for heart failure
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Epidemiology (AREA)
  • Cardiology (AREA)
  • Diabetes (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Molecular Biology (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Hospice & Palliative Care (AREA)
  • Urology & Nephrology (AREA)
  • Biophysics (AREA)
  • Inorganic Chemistry (AREA)
  • Child & Adolescent Psychology (AREA)
  • Emergency Medicine (AREA)
  • Endocrinology (AREA)
  • Psychiatry (AREA)
  • Rheumatology (AREA)
  • Pain & Pain Management (AREA)
  • Vascular Medicine (AREA)
  • Biochemistry (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)

Abstract

la présente invention concerne un comprimé ou une couche de comprimé pharmaceutique comprenant l'antagoniste du récepteur de l'angiotensine I I telmisartan sous forme amorphe, un agent basique et du sorbitol caractérisé en ce que le sorbitol présente une surface spécifique située entre 0,75 m2/g et 3,5 m2/g.
TNP2009000371A 2007-03-14 2009-09-11 Composition pharmaceutique TN2009000371A1 (fr)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP07104157A EP1970053A1 (fr) 2007-03-14 2007-03-14 Composition pharmaceutique
PCT/EP2008/053009 WO2008110599A1 (fr) 2007-03-14 2008-03-13 Composition pharmaceutique

Publications (1)

Publication Number Publication Date
TN2009000371A1 true TN2009000371A1 (fr) 2010-12-31

Family

ID=38179677

Family Applications (1)

Application Number Title Priority Date Filing Date
TNP2009000371A TN2009000371A1 (fr) 2007-03-14 2009-09-11 Composition pharmaceutique

Country Status (35)

Country Link
US (1) US20100143465A1 (fr)
EP (2) EP1970053A1 (fr)
JP (1) JP5742045B2 (fr)
KR (1) KR101503674B1 (fr)
CN (1) CN101641084B (fr)
AR (1) AR065726A1 (fr)
AT (1) ATE493119T1 (fr)
AU (1) AU2008225754B2 (fr)
BR (1) BRPI0808797A2 (fr)
CA (1) CA2680608C (fr)
CL (1) CL2008000733A1 (fr)
CO (1) CO6220927A2 (fr)
CY (1) CY1111350T1 (fr)
DE (1) DE602008004217D1 (fr)
DK (1) DK2120884T3 (fr)
EA (1) EA018574B1 (fr)
EC (1) ECSP099629A (fr)
ES (1) ES2358770T3 (fr)
HR (1) HRP20110012T1 (fr)
IL (1) IL200125A (fr)
MA (1) MA31251B1 (fr)
MX (1) MX2009009201A (fr)
MY (1) MY145089A (fr)
NZ (1) NZ580185A (fr)
PE (1) PE20090165A1 (fr)
PL (1) PL2120884T3 (fr)
PT (1) PT2120884E (fr)
RS (1) RS51584B (fr)
SI (1) SI2120884T1 (fr)
TN (1) TN2009000371A1 (fr)
TW (1) TWI406678B (fr)
UA (1) UA96982C2 (fr)
UY (1) UY30961A1 (fr)
WO (1) WO2008110599A1 (fr)
ZA (1) ZA200905224B (fr)

Families Citing this family (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1908469A1 (fr) 2006-10-06 2008-04-09 Boehringer Ingelheim Vetmedica Gmbh Antagonistes du récepteur de l'angiotensine II pour traiter des désordres sistémiques des chats
WO2009058950A2 (fr) * 2007-10-30 2009-05-07 Dr. Reddy's Laboratories Ltd. Formulations pharmaceutiques comprenant du telmisartan et de l'hydrochlorotiazide
WO2009135646A2 (fr) 2008-05-05 2009-11-12 Farmaprojects, Sa Compositions pharmaceutiques stables et procédés de préparation desdites compositions adaptés à l’échelle industrielle
CZ2008469A3 (cs) * 2008-07-31 2009-10-29 Zentiva, A. S. Telmisartan tablety
GB0822171D0 (en) * 2008-12-04 2009-01-14 Arrow Int Ltd Temisartan formulations
EP2432452B1 (fr) 2009-05-20 2016-07-27 Boehringer Ingelheim Vetmedica GmbH Une solution pharmaceutique à boire contenant telmisartan
MX377674B (es) * 2012-03-19 2025-03-11 Althera Life Sciencies Llc Formulacion de tableta oral solida de rosuvastatina de liberacion inmediata y metformina de liberacion prolongada.
JP6344678B2 (ja) * 2013-09-27 2018-06-20 キョーリンリメディオ株式会社 テルミサルタン含有製剤及びその製造方法
JP6096328B2 (ja) * 2014-02-10 2017-03-15 富士フイルム株式会社 口腔内崩壊錠
BE1021954B1 (nl) * 2014-06-05 2016-01-28 Syral Belgium Nv Samenstelling van sorbitol met lage friabiliteit
FR3023128B1 (fr) 2014-07-01 2017-11-10 Roquette Freres Nouvelle composition edulcorante
JP5871294B1 (ja) * 2015-02-27 2016-03-01 ベーリンガー インゲルハイム インターナショナル ゲゼルシャフト ミット ベシュレンクテル ハフツング 即時放出経口錠剤
KR20170001921A (ko) 2015-06-26 2017-01-05 대원제약주식회사 안정성이 개선된 텔미사르탄을 함유하는 약제학적 조성물 및 이의 제조방법
CN106420739A (zh) * 2016-10-31 2017-02-22 扬子江药业集团四川海蓉药业有限公司 一种替米沙坦氨氯地平双层片及其制备方法
CN106800537B (zh) 2017-01-18 2019-02-01 广东隆赋药业股份有限公司 丁苯酞-替米沙坦杂合物及其制备方法和用途
CN109316451B (zh) * 2017-07-31 2022-07-01 武汉朗来科技发展有限公司 治疗高血压和相关疾病的口服固体制剂
ES3041575T3 (en) 2018-05-02 2025-11-13 Ferring Bv Improved pharmaceutical formulations

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3245170A1 (de) * 1982-12-07 1984-06-07 Merck Patent Gmbh, 6100 Darmstadt Verbesserter sorbit, verfahren zur herstellung und verwendung
AU1042199A (en) * 1998-11-06 2000-05-29 Boehringer Ingelheim International Gmbh Antihypertensive medicaments containing lacidipine and telmisartan
FR2787110B1 (fr) * 1998-12-11 2001-02-16 Roquette Freres Sorbitol pulverulent et son procede de preparation
NO345891B1 (no) * 2002-01-16 2021-09-27 Boehringer Ingelheim Pharma Tosjikts farmasøytisk tablett for anvendelse ved en metode for behandling av hypertensjon omfattende telmisartan og et diuretisk middel
DE10244681A1 (de) * 2002-09-24 2004-04-08 Boehringer Ingelheim International Gmbh Neue feste Telmisartan enthaltende pharmazeutische Formulierungen und deren Herstellung
DE102004008804A1 (de) * 2004-02-20 2005-09-08 Boehringer Ingelheim Pharma Gmbh & Co. Kg Mehrschichttablette
US20060078615A1 (en) * 2004-10-12 2006-04-13 Boehringer Ingelheim International Gmbh Bilayer tablet of telmisartan and simvastatin
SI1814527T1 (sl) * 2004-11-05 2014-03-31 Boehringer Ingelheim International Gmbh Dvoslojna tableta, ki obsega telmisartan in amlodipin
CA2589493A1 (fr) * 2004-12-17 2006-06-22 Boehringer Ingelheim International Gmbh Therapie combinatoire impliquant le telmisartan et l'hydrochlorothiazide
US20060159747A1 (en) * 2004-12-17 2006-07-20 Boehringer Ingelheim International Gmbh Telmisartan and hydrochlorothiazide combination therapy

Also Published As

Publication number Publication date
CA2680608A1 (fr) 2008-09-18
EP1970053A1 (fr) 2008-09-17
EA018574B1 (ru) 2013-09-30
TWI406678B (zh) 2013-09-01
ZA200905224B (en) 2010-04-28
WO2008110599A1 (fr) 2008-09-18
AU2008225754B2 (en) 2013-04-04
NZ580185A (en) 2011-11-25
CA2680608C (fr) 2015-06-16
RS51584B (sr) 2011-08-31
CL2008000733A1 (es) 2008-07-04
ECSP099629A (es) 2009-10-30
EA200901169A1 (ru) 2010-04-30
AU2008225754A1 (en) 2008-09-18
MX2009009201A (es) 2009-09-08
IL200125A0 (en) 2010-04-15
UA96982C2 (ru) 2011-12-26
MY145089A (en) 2011-12-30
DK2120884T3 (da) 2011-02-07
HK1140692A1 (en) 2010-10-22
JP2010530844A (ja) 2010-09-16
KR101503674B1 (ko) 2015-03-18
SI2120884T1 (sl) 2011-04-29
ATE493119T1 (de) 2011-01-15
PT2120884E (pt) 2011-02-10
EP2120884B1 (fr) 2010-12-29
MA31251B1 (fr) 2010-03-01
HRP20110012T1 (hr) 2011-02-28
EP2120884A1 (fr) 2009-11-25
CO6220927A2 (es) 2010-11-19
BRPI0808797A2 (pt) 2013-01-15
CN101641084A (zh) 2010-02-03
KR20090119998A (ko) 2009-11-23
US20100143465A1 (en) 2010-06-10
IL200125A (en) 2012-01-31
AR065726A1 (es) 2009-06-24
CN101641084B (zh) 2013-04-10
PE20090165A1 (es) 2009-03-31
ES2358770T3 (es) 2011-05-13
PL2120884T3 (pl) 2011-05-31
UY30961A1 (es) 2008-10-31
DE602008004217D1 (de) 2011-02-10
CY1111350T1 (el) 2015-08-05
TW200900095A (en) 2009-01-01
JP5742045B2 (ja) 2015-07-01

Similar Documents

Publication Publication Date Title
TN2009000371A1 (fr) Composition pharmaceutique
UA95768C2 (ru) Антагонисты мускариновых рецепторов ацетилхолина
LU92550I2 (fr) Lurasidone, facultativement sous forme de sa base libre ou de ses sels pharmaceutiquement acceptables
ATE469895T1 (de) Cgrp-rezeptorantagonisten
ECSP066468A (es) Antagonistas de receptores muscarínicos de acetilcolina
EP2244575A4 (fr) Antagonistes du récepteur de l'angiotensine ii
CL2013001885A1 (es) Compuestos derivados de morfina, antagonistas del receptor ipiode periferico; composicion farmaceutica; formulacion oral; y uso para reducir los efectos colaterales de la terapia opioide (div. sol. 905-08).
EP2049110A4 (fr) Diazépans pontés antagonistes du récepteur de l'oréxine
CL2007002017A1 (es) Compuestos derivados de [4,5']-bipirimidinil-6,4'-diamina; composicion farmaceutica; y uso como inhibidor de la actividad de cinasa en cancer de vejiga, cancer cervical y mieloma multiple.
EP2019857A4 (fr) Combinaison adjuvante synergique d'anticorps agoniste cd40/interféron de type 1, conjugués contenant une telle combinaison et utilisation en tant qu'agent thérapeutique pour améliorer l'immunite cellulaire
DE602007012072D1 (de) Orantagonisten
ATE481405T1 (de) Thiazolpyrazolopyrimidine als antagonisten des crf1-rezeptors
NL1028624A1 (nl) Alfa-aryl- of -heteroarylmethyl-bèta-piperidinopropaan-zuurverbindingen als ORL1-receptorantagonisten.
BR112012024139A2 (pt) formulações farmacêuticas de camada dupla contendo agonistas e antagonistas de opióide.
IL187426A0 (en) Piperidin-4-yl-amide derivatives and their use as sst receptor subtype 5 antagonists
ATE458740T1 (de) 1,4,5,6,7,8-hexahydro-1,2,5-triaza-azulen- derivate als orexinrezeptor-antagonisten
EA201001312A1 (ru) Твердая фармацевтическая композиция, содержащая непептидный антагонист рецептора ангиотензина ii и диуретик
NZ597648A (en) Angiotensin II receptor antagonist for the prevention or treatment of systemic diseases in cats
CL2007003198A1 (es) Compuestos diarilicos opcionalmente nitrogenados, antagonistas de los receptores opioides; composicion farmaceutica; y uso en el tratamiento de la obesidad.
MX2010008796A (es) Composiciones formadoras de pelicula para el cuidado personal.
EA200700765A1 (ru) Двуслойная таблетка
CL2007003613A1 (es) Compuestos nitroderivados, antagonistas del receptor de angiotensina ii; composicion farmaceutica que comprende a dichos compuestos; y su uso para tratar hipertension.
DK1808446T3 (da) IL-18-receptor-antagonist og farmaceutisk sammensætning indeholdende antagonisten
EP1974619A4 (fr) Matériau pour combinaison sous-marine et combinaison sous-marine utilisant ledit matériau
ATE469900T1 (de) Spiropiperidinderivate als antagonisten des via- rezeptors