TN2009000345A1 - Aryl carboxylic acid cyclohexyl amide derivatives - Google Patents

Aryl carboxylic acid cyclohexyl amide derivatives

Info

Publication number: TN2009000345A1
Authority: TN; Tunisia
Prior art keywords: carboxylic acid; amide derivatives; acid cyclohexyl; aryl carboxylic; cyclohexyl amide
Prior art date: 2007-02-19

Application number

TNP2009000345A

Other languages

English (en)

Inventor

Rene Hersperger

Philipp Janser

Wolfgang Miltz

Original Assignee

Novartis Ag

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2007-02-19

Filing date

2009-08-17

Publication date

2010-12-31

2009-08-17 Application filed by Novartis Ag filed Critical Novartis Ag

2010-12-31 Publication of TN2009000345A1 publication Critical patent/TN2009000345A1/fr

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/14—Antivirals for RNA viruses
- A61P31/18—Antivirals for RNA viruses for HIV
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/14—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing three or more hetero rings
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/14—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing three or more hetero rings
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
- C07D417/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing three or more hetero rings

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Health & Medical Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
General Health & Medical Sciences (AREA)
Veterinary Medicine (AREA)
Medicinal Chemistry (AREA)
Public Health (AREA)
Animal Behavior & Ethology (AREA)
Pharmacology & Pharmacy (AREA)
Chemical Kinetics & Catalysis (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
General Chemical & Material Sciences (AREA)
Bioinformatics & Cheminformatics (AREA)
Virology (AREA)
Immunology (AREA)
Engineering & Computer Science (AREA)
Oncology (AREA)
Communicable Diseases (AREA)
AIDS & HIV (AREA)
Tropical Medicine & Parasitology (AREA)
Pain & Pain Management (AREA)
Rheumatology (AREA)
Epidemiology (AREA)
Molecular Biology (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Plural Heterocyclic Compounds (AREA)
Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Pyrrole Compounds (AREA)
Peptides Or Proteins (AREA)
Hydrogenated Pyridines (AREA)
Pyridine Compounds (AREA)

TNP2009000345A 2007-02-19 2009-08-17 Aryl carboxylic acid cyclohexyl amide derivatives TN2009000345A1 (en)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
EP07102622		2007-02-19
PCT/EP2008/051951 WO2008101905A1 (fr)	2007-02-19	2008-02-18	Dérivés cyclohexyl amide d'acide carboxylique aryle

Publications (1)

Publication Number	Publication Date
TN2009000345A1 true TN2009000345A1 (en)	2010-12-31

Family

ID=38058317

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
TNP2009000345A TN2009000345A1 (en)	2007-02-19	2009-08-17	Aryl carboxylic acid cyclohexyl amide derivatives

Country Status (35)

Country	Link
US (1)	US8354431B2 (fr)
EP (1)	EP2125782B1 (fr)
JP (1)	JP5180234B2 (fr)
KR (1)	KR101070984B1 (fr)
CN (1)	CN101605781B (fr)
AR (1)	AR065369A1 (fr)
AT (1)	ATE518854T1 (fr)
AU (1)	AU2008219317B2 (fr)
BR (1)	BRPI0807625A2 (fr)
CA (1)	CA2677565C (fr)
CL (1)	CL2008000497A1 (fr)
CR (1)	CR10957A (fr)
CY (1)	CY1111984T1 (fr)
DK (1)	DK2125782T3 (fr)
EA (1)	EA017000B1 (fr)
EC (1)	ECSP099584A (fr)
ES (1)	ES2371126T3 (fr)
GT (1)	GT200900226A (fr)
HN (1)	HN2009001607A (fr)
HR (1)	HRP20110793T1 (fr)
IL (1)	IL200191A (fr)
MA (1)	MA31206B1 (fr)
MX (1)	MX2009008145A (fr)
MY (1)	MY147487A (fr)
NZ (1)	NZ578663A (fr)
PE (1)	PE20081785A1 (fr)
PL (1)	PL2125782T3 (fr)
PT (1)	PT2125782E (fr)
RS (1)	RS51986B (fr)
SI (1)	SI2125782T1 (fr)
TN (1)	TN2009000345A1 (fr)
TW (1)	TW200848038A (fr)
UA (1)	UA97389C2 (fr)
WO (1)	WO2008101905A1 (fr)
ZA (1)	ZA200905160B (fr)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US8273900B2 (en)	2008-08-07	2012-09-25	Novartis Ag	Organic compounds
CA3200234A1 (fr)	2020-11-25	2022-06-02	Daryl C. Drummond	Nanoparticules lipidiques utilisees pour l'administration d'acides nucleiques, et methodes d'utilisation associees
IL317109A (en)	2022-05-25	2025-01-01	Akagera Medicines Inc	Lipid nanoparticles for the delivery of nucleic acids and methods of using them

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US6132987A (en)	1994-01-13	2000-10-17	The Regents Of The University Of California	Recombinant mammalian monocyte chemotactic protein-1 (MCP-1) receptors (MCP-1R, CCR-2)
WO1997032019A2 (fr)	1996-03-01	1997-09-04	Euroscreen S.A.	Recepteur-5 de chimiokine cc, recepteur de chimiokines cc, leurs derives et leurs applications
EP0975749A2 (fr) *	1996-05-28	2000-02-02	THE GOVERNMENT OF THE UNITED STATES OF AMERICA, as represented by THE SECRETARY, DEPARTMENT OF HEALTH AND HUMAN SERVICES	Recepteur 5 de cc chemokine, anticorps diriges contre ce dernier et animaux transgeniques
US6388055B1 (en)	1996-10-03	2002-05-14	Smithkline Beecham Corporation	Mouse CC-CKR5 receptor polypeptide
AR008331A1 (es)	1997-01-23	1999-12-29	Smithkline Beecham Corp	Compuestos antagonistas de un receptor de il-8, uso de los mismos para la fabricacion de medicamentos, procedimiento para su obtencion, composicionesfarmaceuticas que los contienen
US6172061B1 (en) *	1997-12-19	2001-01-09	Takeda Chemical Industries, Ltd.	Pharmaceutical composition for antagonizing CCR5 comprising anilide derivative
US6312689B1 (en) *	1998-07-23	2001-11-06	Millennium Pharmaceuticals, Inc.	Anti-CCR2 antibodies and methods of use therefor
US6235771B1 (en) *	1998-12-21	2001-05-22	Takeda Chemical Industries, Ltd.	Anilide derivative, production and use thereof
AU2000227285A1 (en)	2000-01-14	2001-07-24	The Government Of The United States Of America As Represented By The Secretary, Department Of Health And Human Services	Methods of regulating il-12 production by administering ccr5 agonists and antagonists
WO2002020615A2 (fr)	2000-09-08	2002-03-14	Micromet Ag	Constructions d'anticorps et/ou de chimiokine et leur utilisation contre des troubles immunologiques
CA2463198A1 (fr)	2001-10-03	2003-04-17	Ucb, S.A.	Derives pyrrolidinone
WO2004054616A1 (fr) *	2002-12-13	2004-07-01	Ono Pharmaceutical Co., Ltd.	Antagoniste et agoniste se liant a un site de liaison forte du recepteur de la chimiokine
EP1623721A1 (fr) *	2003-05-06	2006-02-08	Ono Pharmaceutical Co., Ltd.	Inhibiteur du fonctionnement de la cellule effectrice
CA2548502A1 (fr) *	2003-12-11	2005-06-30	Yale University	Methodes et compositions relatives a un antagoniste du ccr5, et inflammation induite par ifn-.gamma. et il-13
NZ547316A (en)	2003-12-18	2011-01-28	Incyte Corp	3-cycloalkylaminopyrrolidine derivatives as modulators of chemokine receptors
GB0403038D0 (en) *	2004-02-11	2004-03-17	Novartis Ag	Organic compounds
US7435831B2 (en)	2004-03-03	2008-10-14	Chemocentryx, Inc.	Bicyclic and bridged nitrogen heterocycles
CA2565486A1 (fr) *	2004-05-11	2005-12-08	Incyte Corporation	3-(4-heteroarylcyclohexylamino)cyclopentanecarboxamides utilises comme modulateurs des recepteurs de la chimiokine
GB0412468D0 (en)	2004-06-04	2004-07-07	Astrazeneca Ab	Chemical compounds
WO2007062175A2 (fr)	2005-11-21	2007-05-31	Amgen Inc.	Antagonistes cxcr3
GB0525957D0 (en)	2005-12-21	2006-02-01	Astrazeneca Ab	Methods
BRPI0712843A2 (pt)	2006-06-12	2012-07-31	Pfizer Prod Inc	antagonista de ccr5 e seus usos
US20080076120A1 (en) *	2006-09-14	2008-03-27	Millennium Pharmaceuticals, Inc.	Methods for the identification, evaluation and treatment of patients having CC-Chemokine receptor 2 (CCR-2) mediated disorders
MX2009003762A (es)	2006-10-05	2009-07-10	Centocor Ortho Biotech Inc	Antagonistas del receptor cc-quimiocina 2 para el tratamiento de fibrosis.
WO2008045564A2 (fr)	2006-10-12	2008-04-17	Epix Delaware, Inc.	Composés de carboxamide et leur utilisation
MX2009005252A (es)	2006-11-17	2009-05-28	Abbott Lab	Aminopirrolidinas como antagonistas del receptor de quimiocina.
EP2120928A2 (fr)	2007-02-15	2009-11-25	Pfizer Limited	Compositions pharmaceutiques et procédés pour la fabrication d'antagonistes ccr5
WO2008134076A1 (fr)	2007-04-30	2008-11-06	Progenics Pharmaceuticals, Inc.	Procédés de réduction de la charge virale chez des patients infectés par le vih-1

2008
- 2008-02-15 PE PE2008000326A patent/PE20081785A1/es not_active Application Discontinuation
- 2008-02-15 AR ARP080100655A patent/AR065369A1/es not_active Application Discontinuation
- 2008-02-18 PT PT08709083T patent/PT2125782E/pt unknown
- 2008-02-18 WO PCT/EP2008/051951 patent/WO2008101905A1/fr active Application Filing
- 2008-02-18 JP JP2009549430A patent/JP5180234B2/ja not_active Expired - Fee Related
- 2008-02-18 BR BRPI0807625-1A patent/BRPI0807625A2/pt not_active IP Right Cessation
- 2008-02-18 HR HR20110793T patent/HRP20110793T1/hr unknown
- 2008-02-18 CA CA2677565A patent/CA2677565C/fr not_active Expired - Fee Related
- 2008-02-18 NZ NZ578663A patent/NZ578663A/en not_active IP Right Cessation
- 2008-02-18 AT AT08709083T patent/ATE518854T1/de active
- 2008-02-18 CL CL200800497A patent/CL2008000497A1/es unknown
- 2008-02-18 MX MX2009008145A patent/MX2009008145A/es active IP Right Grant
- 2008-02-18 MY MYPI20093281A patent/MY147487A/en unknown
- 2008-02-18 TW TW097105608A patent/TW200848038A/zh unknown
- 2008-02-18 ES ES08709083T patent/ES2371126T3/es active Active
- 2008-02-18 PL PL08709083T patent/PL2125782T3/pl unknown
- 2008-02-18 EA EA200901085A patent/EA017000B1/ru not_active IP Right Cessation
- 2008-02-18 KR KR1020097017079A patent/KR101070984B1/ko not_active Expired - Fee Related
- 2008-02-18 EP EP08709083A patent/EP2125782B1/fr active Active
- 2008-02-18 SI SI200830417T patent/SI2125782T1/sl unknown
- 2008-02-18 RS RS20110474A patent/RS51986B/en unknown
- 2008-02-18 AU AU2008219317A patent/AU2008219317B2/en not_active Ceased
- 2008-02-18 CN CN200880004192.6A patent/CN101605781B/zh not_active Expired - Fee Related
- 2008-02-18 US US12/527,469 patent/US8354431B2/en not_active Expired - Fee Related
- 2008-02-18 UA UAA200908589A patent/UA97389C2/ru unknown
- 2008-02-18 DK DK08709083.3T patent/DK2125782T3/da active
2009
- 2009-07-23 ZA ZA200905160A patent/ZA200905160B/xx unknown
- 2009-07-24 CR CR10957A patent/CR10957A/es not_active Application Discontinuation
- 2009-07-30 IL IL200191A patent/IL200191A/en not_active IP Right Cessation
- 2009-08-12 GT GT200900226A patent/GT200900226A/es unknown
- 2009-08-17 TN TNP2009000345A patent/TN2009000345A1/fr unknown
- 2009-08-17 EC EC2009009584A patent/ECSP099584A/es unknown
- 2009-08-18 HN HN2009001607A patent/HN2009001607A/es unknown
- 2009-08-31 MA MA32193A patent/MA31206B1/fr unknown
2011
- 2011-11-02 CY CY20111101048T patent/CY1111984T1/el unknown

Also Published As

Publication number	Publication date
HN2009001607A (es)	2011-11-23
GT200900226A (es)	2010-07-02
CY1111984T1 (el)	2015-11-04
DK2125782T3 (da)	2011-11-21
AR065369A1 (es)	2009-06-03
US20100016361A1 (en)	2010-01-21
HRP20110793T1 (hr)	2011-11-30
TW200848038A (en)	2008-12-16
CA2677565C (fr)	2014-11-18
NZ578663A (en)	2011-01-28
HK1138836A1 (en)	2010-09-03
JP2010519187A (ja)	2010-06-03
KR101070984B1 (ko)	2011-10-06
AU2008219317A1 (en)	2008-08-28
BRPI0807625A2 (pt)	2014-05-27
PE20081785A1 (es)	2009-01-12
MX2009008145A (es)	2009-08-12
ZA200905160B (en)	2010-05-26
EP2125782B1 (fr)	2011-08-03
CN101605781A (zh)	2009-12-16
ES2371126T3 (es)	2011-12-27
US8354431B2 (en)	2013-01-15
IL200191A0 (en)	2010-04-15
PL2125782T3 (pl)	2011-12-30
ATE518854T1 (de)	2011-08-15
WO2008101905A1 (fr)	2008-08-28
EP2125782A1 (fr)	2009-12-02
EA200901085A1 (ru)	2010-02-26
KR20090103943A (ko)	2009-10-01
EA017000B1 (ru)	2012-09-28
JP5180234B2 (ja)	2013-04-10
PT2125782E (pt)	2011-11-17
SI2125782T1 (sl)	2011-12-30
RS51986B (en)	2012-02-29
CL2008000497A1 (es)	2008-08-29
AU2008219317B2 (en)	2011-09-08
CN101605781B (zh)	2014-08-13
MA31206B1 (fr)	2010-02-01
UA97389C2 (en)	2012-02-10
ECSP099584A (es)	2009-09-29
MY147487A (en)	2012-12-14
CA2677565A1 (fr)	2008-08-28
CR10957A (es)	2009-09-01
IL200191A (en)	2013-12-31

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