TN2009000137A1 - Substituted 2,3-dihydroimidazo[1,2-c]quinazoline derivatives useful for treating hyper-proliferative disorders and diseases associated with angiogenesis - Google Patents

Substituted 2,3-dihydroimidazo[1,2-c]quinazoline derivatives useful for treating hyper-proliferative disorders and diseases associated with angiogenesis

Info

Publication number: TN2009000137A1
Authority: TN; Tunisia
Prior art keywords: dihydroimidazo; diseases associated; angiogenesis; substituted; proliferative disorders
Prior art date: 2006-12-05

Application number

TNP2009000137A

Other languages

English (en)

Inventor

Martin Hentemann

Jill Wood

William Scott

Martin Michels

Ann-Marie Campbell

Ann-Marie Bullion

R Bruce Rowley

Aniko Redman

Original Assignee

Bayer Schering Pharma Ag

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2006-12-05

Filing date

2009-04-13

Publication date

2010-10-18

Family has litigation

First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=39492563&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=TN2009000137(A1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.

2009-04-13 Application filed by Bayer Schering Pharma Ag filed Critical Bayer Schering Pharma Ag

2010-10-18 Publication of TN2009000137A1 publication Critical patent/TN2009000137A1/fr

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
- C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
- C07D487/04—Ortho-condensed systems
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
- A01N43/00—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds
- A01N43/48—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds having rings with two nitrogen atoms as the only ring hetero atoms
- A01N43/54—1,3-Diazines; Hydrogenated 1,3-diazines
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
- A01N43/00—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds
- A01N43/90—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds having two or more relevant hetero rings, condensed among themselves or with a common carbocyclic ring system
- A—HUMAN NECESSITIES
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- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
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- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
- A61K31/517—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with carbocyclic ring systems, e.g. quinazoline, perimidine
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- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
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- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
- A61K31/519—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with heterocyclic rings
- A—HUMAN NECESSITIES
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- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/535—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one oxygen as the ring hetero atoms, e.g. 1,2-oxazines
- A61K31/5375—1,4-Oxazines, e.g. morpholine
- A61K31/5377—1,4-Oxazines, e.g. morpholine not condensed and containing further heterocyclic rings, e.g. timolol
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- A61P9/00—Drugs for disorders of the cardiovascular system
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- A61P9/12—Antihypertensives
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
- C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings

Landscapes

Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Life Sciences & Earth Sciences (AREA)
General Health & Medical Sciences (AREA)
Public Health (AREA)
Medicinal Chemistry (AREA)
Veterinary Medicine (AREA)
Animal Behavior & Ethology (AREA)
Pharmacology & Pharmacy (AREA)
Engineering & Computer Science (AREA)
Bioinformatics & Cheminformatics (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Chemical Kinetics & Catalysis (AREA)
General Chemical & Material Sciences (AREA)
Epidemiology (AREA)
Immunology (AREA)
Cardiology (AREA)
Diabetes (AREA)
Heart & Thoracic Surgery (AREA)
Hematology (AREA)
Agronomy & Crop Science (AREA)
Pest Control & Pesticides (AREA)
Environmental Sciences (AREA)
Zoology (AREA)
Wood Science & Technology (AREA)
Dentistry (AREA)
Plant Pathology (AREA)
Biomedical Technology (AREA)
Neurology (AREA)
Neurosurgery (AREA)
Ophthalmology & Optometry (AREA)
Hospice & Palliative Care (AREA)
Obesity (AREA)
Rheumatology (AREA)
Urology & Nephrology (AREA)
Psychiatry (AREA)
Oncology (AREA)
Pulmonology (AREA)
Transplantation (AREA)

TNP2009000137A 2006-12-05 2009-04-13 Substituted 2,3-dihydroimidazo[1,2-c]quinazoline derivatives useful for treating hyper-proliferative disorders and diseases associated with angiogenesis TN2009000137A1 (en)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
US87309006P	2006-12-05	2006-12-05
PCT/US2007/024985 WO2008070150A1 (fr)	2006-12-05	2007-12-05	Produits dérivés de 2,3-dihydroimidazo[1,2-c]quinazoline substitués, utiles pour le traitement de troubles hyperlifératifs et de maladies associées à une angiogénèse

Publications (1)

Publication Number	Publication Date
TN2009000137A1 true TN2009000137A1 (en)	2010-10-18

Family

ID=39492563

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
TNP2009000137A TN2009000137A1 (en)	2006-12-05	2009-04-13	Substituted 2,3-dihydroimidazo[1,2-c]quinazoline derivatives useful for treating hyper-proliferative disorders and diseases associated with angiogenesis

Country Status (41)

Country	Link
US (3)	USRE46856E1 (fr)
EP (1)	EP2096919B1 (fr)
JP (1)	JP5326092B2 (fr)
KR (1)	KR101501785B1 (fr)
CN (4)	CN108774232B (fr)
AR (1)	AR064106A1 (fr)
AU (1)	AU2007328008B2 (fr)
BR (1)	BRPI0720178B8 (fr)
CA (1)	CA2671614C (fr)
CL (1)	CL2007003508A1 (fr)
CO (1)	CO6220908A2 (fr)
CR (1)	CR10838A (fr)
CU (1)	CU23796B7 (fr)
DK (1)	DK2096919T3 (fr)
DO (1)	DOP2009000135A (fr)
EA (1)	EA018839B1 (fr)
EC (1)	ECSP099387A (fr)
ES (1)	ES2572189T3 (fr)
GT (1)	GT200900154A (fr)
HN (1)	HN2009001131A (fr)
HU (1)	HUE028773T2 (fr)
IL (1)	IL198273A (fr)
JO (1)	JO3147B1 (fr)
MA (1)	MA31283B1 (fr)
MX (1)	MX2009006001A (fr)
MY (1)	MY157944A (fr)
NO (1)	NO342348B1 (fr)
NZ (1)	NZ577342A (fr)
PA (1)	PA8759601A1 (fr)
PE (1)	PE20081444A1 (fr)
PL (1)	PL2096919T3 (fr)
RS (1)	RS56045B1 (fr)
SG (1)	SG177170A1 (fr)
SI (1)	SI2096919T1 (fr)
SV (1)	SV2009003288A (fr)
TN (1)	TN2009000137A1 (fr)
TW (1)	TWI406662B (fr)
UA (1)	UA96965C2 (fr)
UY (1)	UY30761A1 (fr)
WO (1)	WO2008070150A1 (fr)
ZA (1)	ZA200904691B (fr)

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WO2010082627A1 (fr)	2009-01-16	2010-07-22	ダイソー株式会社	Procédé de production d'un sel de la 2-hydroxyméthylmorpholine
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EP2508525A1 (fr) *	2011-04-05	2012-10-10	Bayer Pharma Aktiengesellschaft	Sels de 2,3-dihydroimidazo[1,2-C]quinazoline substitutés
JO3733B1 (ar) *	2011-04-05	2021-01-31	Bayer Ip Gmbh	استخدام 3,2-دايهيدروايميدازو[1, 2 -c]كوينازولينات مستبدلة
EP2567959B1 (fr)	2011-09-12	2014-04-16	Sanofi	Dérivés d'amide d'acide 6-(4-hydroxy-phényl)-3-styryl-1h-pyrazolo[3,4-b]pyridine-4-carboxylique en tant qu'inhibiteurs de kinase
WO2013037390A1 (fr)	2011-09-12	2013-03-21	Sanofi	Dérivés amides d'acide 6-(4-hydroxyphényl)-3-styryl-1h-pyrazolo[3,4-b]pyridine-4-carboxylique en tant qu'inhibiteurs de kinase
WO2013045413A1 (fr)	2011-09-27	2013-04-04	Sanofi	Dérivés d'amide d'acide 6-(4-hydroxyphényl)-3-alkyl-1h-pyrazolo[3,4-b] pyridine-4-carboxylique utilisés comme inhibiteurs de kinase
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2007
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Publication number	Publication date
SV2009003288A (es)	2009-10-02
US20130261113A1 (en)	2013-10-03
JO3147B1 (ar)	2017-09-20
PA8759601A1 (es)	2009-02-09
NO342348B1 (no)	2018-05-07
CN108774232B (zh)	2022-08-09
BRPI0720178B1 (pt)	2019-04-09
RS56045B1 (sr)	2017-09-29
KR20090096440A (ko)	2009-09-10
HN2009001131A (es)	2012-02-06
CL2007003508A1 (es)	2008-07-04
CU20090103A7 (es)	2011-12-28
ZA200904691B (en)	2010-09-29
EA018839B1 (ru)	2013-11-29
WO2008070150A1 (fr)	2008-06-12
JP2010511718A (ja)	2010-04-15
NO20092529L (no)	2009-08-27
PE20081444A1 (es)	2008-11-29
CN105254634B (zh)	2022-05-27
US20110083984A1 (en)	2011-04-14
KR101501785B1 (ko)	2015-03-11
EP2096919A1 (fr)	2009-09-09
HUE028773T2 (en)	2017-01-30
TWI406662B (zh)	2013-09-01
SI2096919T1 (sl)	2016-06-30
ES2572189T3 (es)	2016-05-30
AU2007328008A1 (en)	2008-06-12
AU2007328008B2 (en)	2014-03-13
IL198273A0 (en)	2009-12-24
ECSP099387A (es)	2009-11-30
IL198273A (en)	2015-07-30
MX2009006001A (es)	2009-06-16
GT200900154A (es)	2012-01-17
EA200900733A1 (ru)	2009-12-30
TW200840582A (en)	2008-10-16
HK1217953A1 (zh)	2017-01-27
UA96965C2 (ru)	2011-12-26
CN108774232A (zh)	2018-11-09
DK2096919T3 (en)	2016-05-17
CO6220908A2 (es)	2010-11-19
MY157944A (en)	2016-08-30
CR10838A (es)	2009-11-05
NZ577342A (en)	2012-01-12
CN105254634A (zh)	2016-01-20
CN101631464B (zh)	2022-12-06
CU23796B7 (es)	2012-03-15
CA2671614A1 (fr)	2008-06-12
CN101631464A (zh)	2010-01-20
CA2671614C (fr)	2016-01-26
DOP2009000135A (es)	2009-06-30
BRPI0720178B8 (pt)	2021-05-25
MA31283B1 (fr)	2010-04-01
USRE46856E1 (en)	2018-05-22
JP5326092B2 (ja)	2013-10-30
UY30761A1 (es)	2008-07-03
SG177170A1 (en)	2012-01-30
BRPI0720178A2 (pt)	2013-12-24
AR064106A1 (es)	2009-03-11
EP2096919B1 (fr)	2016-03-02
CN115724847A (zh)	2023-03-03
PL2096919T3 (pl)	2016-08-31
US8466283B2 (en)	2013-06-18
EP2096919A4 (fr)	2010-11-17

Publication	Publication Date	Title
TN2009000137A1 (en)	2010-10-18	Substituted 2,3-dihydroimidazo[1,2-c]quinazoline derivatives useful for treating hyper-proliferative disorders and diseases associated with angiogenesis
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WO2009091550A8 (fr)	2010-08-26	Dérivés de 2,3-dihydroimidazo [1,2-c] quinazoline à substitution sulfone utilisés pour traiter des troubles hyperproliférants et des maladies associées à l'angiogénèse
WO2007064931A3 (fr)	2007-07-19	Derives substitues de 4-amino-pyrrolotriazine utiles dans le traitement de troubles hyperproliferatifs et de maladies associees a l'angiogenese
MY143795A (en)	2011-07-15	Tetrahydropyridoindole derivatives
MY144992A (en)	2011-12-15	Substituted 1,2,3,4-tetrahydroisoquinoline derivatives.
WO2005004818A3 (fr)	2005-05-06	Composes heterocycliques et leur utilisation comme agents anticancereux
MX2009012000A (es)	2009-11-19	Derivados de pirazol heteroarilo sustituidos utiles para el tratamiento de trastornos hiperproliferativos y enfermedades asociadas a la angiogenesis.
MY191349A (en)	2022-06-17	New pharmaceutical compositions for the treatment of hyper-proliferative disorders
MX2009004745A (es)	2009-05-22	Derivados de 1,2,3-triazol como inhibidores del receptor sigma.
DE602005021770D1 (de)	2010-07-22	Indol-1-yl-essigsäurederivate
MY144897A (en)	2011-11-30	2,3,4,9-tetrahydro-1h-carbazole derivatives as crth2 receptor antagonists
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TW200628468A (en)	2006-08-16	Bicyclononene derivatives
MY148611A (en)	2013-05-15	Imino-imidazo-pyridine derivatives having antithrombotic activity
TN2013000204A1 (en)	2014-11-10	Aminoalcohol substituted 2,3-dihydroimidazo[1,2-c]quinazoline derivatives useful for treating hyper-proliferative disorders and diseases associated with angiogenesis
WO2006110447A3 (fr)	2007-01-18	Derives de pyrimidine
TH85706B (th)	2021-12-07	อนุพันธ์ 2,3-ไดไฮโดรอิมิดาโซ[1,2-c]ควินาโซลีนถูกแทนที่ (Substituted 2,3-dihydromidazo[1,2-c]quinazoline Derivatives) ซึ่งเป็นประโยชน์สำหรับการรักษาความผิดปกติด้านงอกขยายเกินปกติ และ โรคที่มีส่วนสัมพันธ์กับการก่อเกิดหลอดเลือดใหม่
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TW200603791A (en)	2006-02-01	Compounds and compositions as cathepsin S inhibitors
CY1117512T1 (el)	2017-04-26	Υποκατεστημενα παραγωγα 2,3-δiυδpoϊmiδazo[1,2-c] κιναζολινης χρησιμα στη θεραπευτικη αντιμετωπιση υπερ-πολλαπλασιαστικων διαταραχων και παθησεων που σχετιζονται με την αγγειογενεση