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TN2009000099A1 - Reconstituted surfactants having improved properties - Google Patents

Reconstituted surfactants having improved properties

Info

Publication number
TN2009000099A1
TN2009000099A1 TN2009000099A TN2009000099A TN2009000099A1 TN 2009000099 A1 TN2009000099 A1 TN 2009000099A1 TN 2009000099 A TN2009000099 A TN 2009000099A TN 2009000099 A TN2009000099 A TN 2009000099A TN 2009000099 A1 TN2009000099 A1 TN 2009000099A1
Authority
TN
Tunisia
Prior art keywords
improved properties
reconstituted surfactants
reconstituted
directed
surfactants
Prior art date
Application number
TN2009000099A
Other languages
French (fr)
Inventor
Jan Johansson
Tore Curstedt
Bengt Robertson
Original Assignee
Chiesi Farma Spa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=39079026&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=TN2009000099(A1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Chiesi Farma Spa filed Critical Chiesi Farma Spa
Publication of TN2009000099A1 publication Critical patent/TN2009000099A1/en

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/02—Peptides of undefined number of amino acids; Derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/395—Alveolar surfactant peptides; Pulmonary surfactant peptides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/16—Central respiratory analeptics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/785—Alveolar surfactant peptides; Pulmonary surfactant peptides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Pulmonology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Engineering & Computer Science (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Zoology (AREA)
  • Immunology (AREA)
  • Epidemiology (AREA)
  • Genetics & Genomics (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Toxicology (AREA)
  • Molecular Biology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Medicinal Preparation (AREA)
  • Emulsifying, Dispersing, Foam-Producing Or Wetting Agents (AREA)
  • Fire-Extinguishing Compositions (AREA)

Abstract

The present invention is directed to a reconstituted surfactant comprising a lipid carrier, a polypeptide analogue of the native surfactant protein SP-C, and a polypeptide analogue of the native surfactant protein SP-B. The invention is also directed to the pharmaceutical compositions thereof and to its use for the treatment or prophylaxis of RDS and other respiratory disorders.
TN2009000099A 2006-10-13 2009-03-25 Reconstituted surfactants having improved properties TN2009000099A1 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP06021521 2006-10-13
PCT/IB2007/002841 WO2008044109A1 (en) 2006-10-13 2007-09-28 Reconstituted surfactants having improved properties

Publications (1)

Publication Number Publication Date
TN2009000099A1 true TN2009000099A1 (en) 2010-08-19

Family

ID=39079026

Family Applications (1)

Application Number Title Priority Date Filing Date
TN2009000099A TN2009000099A1 (en) 2006-10-13 2009-03-25 Reconstituted surfactants having improved properties

Country Status (35)

Country Link
US (2) US8183210B2 (en)
EP (1) EP2078038B1 (en)
JP (2) JP5405307B2 (en)
KR (1) KR101328851B1 (en)
CN (2) CN103169947B (en)
AR (2) AR063263A1 (en)
AU (1) AU2007306075B2 (en)
BR (1) BRPI0715317B1 (en)
CA (1) CA2666344C (en)
CL (1) CL2007002931A1 (en)
CO (1) CO6400235A2 (en)
CY (1) CY1114716T1 (en)
DK (1) DK2078038T3 (en)
EA (1) EA015802B1 (en)
ES (1) ES2438727T3 (en)
GE (1) GEP20125531B (en)
HR (1) HRP20140052T1 (en)
IL (1) IL198075A (en)
JO (1) JO2963B1 (en)
MA (1) MA31062B1 (en)
ME (2) ME02326B (en)
MX (1) MX343064B (en)
MY (1) MY148127A (en)
NO (1) NO342038B1 (en)
NZ (1) NZ576189A (en)
PE (1) PE20081184A1 (en)
PL (1) PL2078038T3 (en)
PT (1) PT2078038E (en)
RS (1) RS53172B (en)
SI (1) SI2078038T1 (en)
TN (1) TN2009000099A1 (en)
TW (1) TWI388333B (en)
UA (1) UA94477C2 (en)
WO (1) WO2008044109A1 (en)
ZA (1) ZA200902481B (en)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2658478C (en) 2006-07-20 2018-02-13 University Of Rochester Synthetic lung surfactant and use thereof
EP1997502A1 (en) * 2007-06-01 2008-12-03 CHIESI FARMACEUTICI S.p.A. Reconstituted surfactants having improved properties
US8399406B2 (en) * 2009-06-05 2013-03-19 Chiesi Farmaceutici S.P.A. Reconstituted surfactant composition containing analogs of surfactant protein B (SP-B) and surfactant protein C (SP-C)
CN101948526B (en) * 2010-09-02 2012-12-05 华东理工大学 Method for separating and purifying pulmonary alveoli surface active proteins (SP-B and SP-C)
US9815869B2 (en) 2012-02-09 2017-11-14 University Of Rochester SP-B and SP-C peptides, synthetic lung surfactants, and use thereof
US20130303726A1 (en) * 2012-04-17 2013-11-14 Chiesi Farmaceutici S.P.A. Method for the preparation of surfactant peptides
EP2922868B1 (en) * 2012-11-21 2017-09-27 Chiesi Farmaceutici S.p.A. Reconstituted pulmonary surfactants
US10717777B2 (en) 2015-12-17 2020-07-21 The Lundquist Institute for Biomedical Innovation at Harbor-UCLA Medical Center Synthetic lung surfactant with enhanced stability and effectiveness
EP3452041A4 (en) 2016-03-07 2020-11-11 Los Angeles Biomedical Research Institute at Harbor-UCLA Medical Center COMPOSITIONS AND METHOD OF ADMINISTRATION OF PPAR AGONISTS, SURFACTANT PEPTIDES AND PHOSPHOLIPIDS
CA3029456A1 (en) 2016-08-24 2018-03-01 Chiesi Farmaceutici S.P.A. Stable pharmaceutical formulation comprising a reconstituted pulmonary surfactant composition
WO2021151853A1 (en) 2020-01-28 2021-08-05 Chiesi Farmaceutici S.P.A. Polypeptides having improved properties
EP4228691A4 (en) * 2020-10-16 2025-01-01 Biosuperior Technology, Inc. LUNG TREATMENT COMPOSITIONS
WO2025024609A1 (en) * 2023-07-25 2025-01-30 Biosuperior Technology, Inc. Polypeptides for lung surfactant compositions

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2163860A1 (en) * 1993-06-30 1995-01-12 Chung C. Hsu Method for preparing liposomes
IT1308180B1 (en) * 1999-02-12 2001-12-07 Chiesi Farma Spa SYNTHETIC PEPTIDES HAVING THE ABILITY TO DECREASE SURFACE TENSION AND THEIR USE IN THE PREPARATION OF A SURFACTANT
US7065342B1 (en) * 1999-11-23 2006-06-20 Gofigure, L.L.C. System and mobile cellular telephone device for playing recorded music
ITMI20021058A1 (en) 2002-05-17 2003-11-17 Chiesi Farma Spa MIXTURES OF SYNTHETIC LIPIDS OPTIMIZED FOR THE PREPARATION OF A RECONSTITUTED SURFACTANT
EP1481665A1 (en) * 2003-05-30 2004-12-01 CHIESI FARMACEUTICI S.p.A. Novel lipid mixtures for synthetic surfactants
CA2658478C (en) * 2006-07-20 2018-02-13 University Of Rochester Synthetic lung surfactant and use thereof
EP1997502A1 (en) 2007-06-01 2008-12-03 CHIESI FARMACEUTICI S.p.A. Reconstituted surfactants having improved properties
EP2022798A1 (en) 2007-08-09 2009-02-11 CHIESI FARMACEUTICI S.p.A. Synthetic pulmonary surfactant peptides

Also Published As

Publication number Publication date
US9238058B2 (en) 2016-01-19
ES2438727T3 (en) 2014-01-20
SI2078038T1 (en) 2014-02-28
IL198075A (en) 2016-04-21
BRPI0715317A2 (en) 2013-07-09
RS53172B (en) 2014-06-30
HK1185274A1 (en) 2014-02-14
JP2013241449A (en) 2013-12-05
NZ576189A (en) 2011-09-30
AU2007306075B2 (en) 2012-08-09
CA2666344A1 (en) 2008-04-17
TW200824705A (en) 2008-06-16
US8183210B2 (en) 2012-05-22
MA31062B1 (en) 2010-01-04
MX343064B (en) 2016-10-24
CA2666344C (en) 2017-04-18
HK1134497A1 (en) 2010-04-30
NO342038B1 (en) 2018-03-19
MEP12109A (en) 2011-12-20
NO20091441L (en) 2009-06-23
WO2008044109A1 (en) 2008-04-17
PT2078038E (en) 2013-12-12
EA200900373A1 (en) 2009-10-30
AR063263A1 (en) 2009-01-14
CN103169947B (en) 2014-10-29
CO6400235A2 (en) 2012-03-15
CN101522711A (en) 2009-09-02
KR101328851B1 (en) 2013-11-14
ME02326B (en) 2016-06-20
EP2078038A1 (en) 2009-07-15
CY1114716T1 (en) 2016-10-05
EP2078038B1 (en) 2013-11-20
EA015802B1 (en) 2011-12-30
HRP20140052T1 (en) 2014-02-28
MY148127A (en) 2013-02-28
PE20081184A1 (en) 2008-09-26
BRPI0715317B1 (en) 2021-10-05
MX2009003638A (en) 2009-04-22
CL2007002931A1 (en) 2008-03-24
US20130079275A1 (en) 2013-03-28
KR20090083892A (en) 2009-08-04
GEP20125531B (en) 2012-05-25
IL198075A0 (en) 2011-08-01
AU2007306075A1 (en) 2008-04-17
US20100004173A1 (en) 2010-01-07
TWI388333B (en) 2013-03-11
AR113422A2 (en) 2020-04-29
JP2010505937A (en) 2010-02-25
ZA200902481B (en) 2010-07-28
CN103169947A (en) 2013-06-26
DK2078038T3 (en) 2013-12-02
PL2078038T3 (en) 2014-05-30
JO2963B1 (en) 2016-03-15
JP5405307B2 (en) 2014-02-05
CN101522711B (en) 2013-11-13
UA94477C2 (en) 2011-05-10

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