TH44958A - Some 5-alkyl-2-aryl aminophenylacetic acid and its derivatives. - Google Patents
Some 5-alkyl-2-aryl aminophenylacetic acid and its derivatives.Info
- Publication number
- TH44958A TH44958A TH9801003282A TH9801003282A TH44958A TH 44958 A TH44958 A TH 44958A TH 9801003282 A TH9801003282 A TH 9801003282A TH 9801003282 A TH9801003282 A TH 9801003282A TH 44958 A TH44958 A TH 44958A
- Authority
- TH
- Thailand
- Prior art keywords
- fluoro
- chloro
- methyl
- hydrogen
- ethyl
- Prior art date
Links
- 125000001153 fluoro group Chemical group F* 0.000 claims abstract 10
- 229910052739 hydrogen Inorganic materials 0.000 claims abstract 6
- 239000001257 hydrogen Substances 0.000 claims abstract 6
- 125000004435 hydrogen atom Chemical group [H]* 0.000 claims abstract 6
- 125000001309 chloro group Chemical group Cl* 0.000 claims abstract 4
- -1 chloro, methyl Chemical group 0.000 claims abstract 4
- 125000001495 ethyl group Chemical group [H]C([H])([H])C([H])([H])* 0.000 claims abstract 4
- 125000002496 methyl group Chemical group [H]C([H])([H])* 0.000 claims abstract 4
- 239000000126 substance Substances 0.000 claims abstract 4
- 102100038280 Prostaglandin G/H synthase 2 Human genes 0.000 claims abstract 2
- 108050003267 Prostaglandin G/H synthase 2 Proteins 0.000 claims abstract 2
- 229940124639 Selective inhibitor Drugs 0.000 claims abstract 2
- 239000003814 drug Substances 0.000 claims abstract 2
- 229940079593 drug Drugs 0.000 claims abstract 2
- 150000002148 esters Chemical class 0.000 claims abstract 2
- 125000002887 hydroxy group Chemical group [H]O* 0.000 claims abstract 2
- 150000003839 salts Chemical class 0.000 claims abstract 2
Abstract
DC60 (22/09/41) สิ่งที่ได้รับการเปิดเผยไว้ได้แก่สารสูตร I (สูตรเคมี) (I) ซึ่ง R คือเมทธิล หรือเอทธิล; R1 คือ คลอโร หรือฟลูออโร; R2 คือ ไฮโดรเจน หรือ ฟลูออโร; R3 คือ ไฮโดรเจน, ฟลูออโร, คลอโร, เมทธิล, เอทธิล, เมทธอกซี, เอทธอกซี, หรือ ไฮดอรกซี, R4 คือ ไฮโดรเจน หรือฟลูออโร และ R5 คือ คลอโร, ฟลูออโร, ไพรฟลูออโรเมทธิล หรือเมทธิล; เกลือที่ใช้ได้ในทางเภสัชกรรมของสารเหล่านี้ และโปรดรัก เอสเทอร์ที่ใช้ได้ทางเภสัชกรรมของสารเหล่านี้ ในฐานะสารเลือกยับยั้ง COX-2 ไซโคลออกซี- เจนเนส สิทธิบัตรยา DC60 (22/09/41) What was revealed is the formula I (chemical formula) (I) where R is methyl or ethyl; R1 is chloro or fluoro; R2 is hydrogen or fluoro; R3 is hydrogen, fluoro, chloro, methyl, ethyl, methoxy, ethoxy, or hydroxy, R4 is hydrogen or fluoro, and R5 is chloro. Ro, Fluoro, Pyloromethyl or Methyl; The pharmaceutical salts of these substances, and please love the pharmaceutical esters of them. As a selective inhibitor of COX-2 cycloxy-genase, the drug patents
Claims (1)
Publications (1)
| Publication Number | Publication Date |
|---|---|
| TH44958A true TH44958A (en) | 2001-04-30 |
Family
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