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SV1998000135A - Imidazotriazinonas sustituidas por 2-fenilo ref. lea 32733-sv - Google Patents

Imidazotriazinonas sustituidas por 2-fenilo ref. lea 32733-sv

Info

Publication number
SV1998000135A
SV1998000135A SV1998000135A SV1998000135A SV1998000135A SV 1998000135 A SV1998000135 A SV 1998000135A SV 1998000135 A SV1998000135 A SV 1998000135A SV 1998000135 A SV1998000135 A SV 1998000135A SV 1998000135 A SV1998000135 A SV 1998000135A
Authority
SV
El Salvador
Prior art keywords
imidazotriazinonas
replaced
fenilo
ref
read
Prior art date
Application number
SV1998000135A
Other languages
English (en)
Inventor
Ulrich Niewohner
Mazen Es-Sayed
Helmut Haning
Thomas Schenke
Karl-Heinz Schlemmer
Joerg Keldenich
Erwin Bischoff
Elisabeth Perzborn
Klaus Dembowsky
Peter Sserno
Marc Nowakowsky
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed filed Critical
Publication of SV1998000135A publication Critical patent/SV1998000135A/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A61P15/10—Drugs for genital or sexual disorders; Contraceptives for impotence
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
    • C07F9/02—Phosphorus compounds
    • C07F9/547—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom
    • C07F9/6561—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom containing systems of two or more relevant hetero rings condensed among themselves or condensed with a common carbocyclic ring or ring system, with or without other non-condensed hetero rings

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Vascular Medicine (AREA)
  • Urology & Nephrology (AREA)
  • Gynecology & Obstetrics (AREA)
  • Endocrinology (AREA)
  • Reproductive Health (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

LA PRESENTE INVENCIÓN SE RELACIONA CON LAS IMIDAZOTRIAZINONAS SUSTITUIDAS POR 2-FENILO CON RESTOS ALQUILO CORTOS, NO RAMIFICADOS, EN POSICIÓN 9, SE PREPARAN A PARTIR DE LAS CORRESPONDIENTES 2-FENIL-IMIDAZOTRIAZINONAS MEDIANTE CLOROSULFONACIÓN Y TRANFORMACIÓN POSTERIOR CON LAS MISMAS, LOS COMPUESTOS INHIBEN LAS FOSFODIESTERASAS QUE METABOLIZAN EL GMPC Y SON ADECUADOS COMO SUSTANCIAS ACTIVAS EN MEDICAMENTOS PARA EL TRATAMIENTO DE ENFERMEDADES CARDIOVASCULARES Y CEREBRO-VASCULARES Y/O ENFERMEDADES DEL SISTEMA UROGENITAL, ESPECIALMENTE PARA EL TRATAMIENTO DE LA DIFUSIÓN ERÉCTIL
SV1998000135A 1997-11-12 1998-11-12 Imidazotriazinonas sustituidas por 2-fenilo ref. lea 32733-sv SV1998000135A (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE19750085A DE19750085A1 (de) 1997-11-12 1997-11-12 2-Phenyl-substituierte Imidazotriazinone

Publications (1)

Publication Number Publication Date
SV1998000135A true SV1998000135A (es) 1999-03-09

Family

ID=7848473

Family Applications (1)

Application Number Title Priority Date Filing Date
SV1998000135A SV1998000135A (es) 1997-11-12 1998-11-12 Imidazotriazinonas sustituidas por 2-fenilo ref. lea 32733-sv

Country Status (6)

Country Link
DE (1) DE19750085A1 (es)
EC (1) ECSP024267A (es)
GT (1) GT199800183A (es)
RU (1) RU2260593C2 (es)
SV (1) SV1998000135A (es)
ZA (1) ZA9810297B (es)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB0113343D0 (en) * 2001-06-01 2001-07-25 Bayer Ag Novel Heterocycles 2
TWI541244B (zh) * 2010-09-20 2016-07-11 福倫製藥股份有限公司 咪唑三酮化合物
CN102134242B (zh) * 2011-01-21 2013-08-28 浙江大德药业集团有限公司 一种用于治疗阳痿的快速长效的化合物

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB9013750D0 (en) * 1990-06-20 1990-08-08 Pfizer Ltd Therapeutic agents
GB9114760D0 (en) * 1991-07-09 1991-08-28 Pfizer Ltd Therapeutic agents

Also Published As

Publication number Publication date
DE19750085A1 (de) 1999-05-20
ZA9810297B (en) 1999-05-20
GT199800183A (es) 2000-05-04
ECSP024267A (es) 2002-06-26
RU2260593C2 (ru) 2005-09-20

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Legal Events

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