SU1664326A1 - Method for treating periodic acetonemic vomiting of children - Google Patents
Method for treating periodic acetonemic vomiting of children Download PDFInfo
- Publication number
- SU1664326A1 SU1664326A1 SU884425756A SU4425756A SU1664326A1 SU 1664326 A1 SU1664326 A1 SU 1664326A1 SU 884425756 A SU884425756 A SU 884425756A SU 4425756 A SU4425756 A SU 4425756A SU 1664326 A1 SU1664326 A1 SU 1664326A1
- Authority
- SU
- USSR - Soviet Union
- Prior art keywords
- vomiting
- children
- disease
- acetonemic
- attack
- Prior art date
Links
- 238000000034 method Methods 0.000 title claims description 6
- 206010058938 Acetonaemic vomiting Diseases 0.000 title description 3
- 230000000737 periodic effect Effects 0.000 title description 2
- 201000010099 disease Diseases 0.000 claims abstract description 6
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 claims abstract description 6
- 239000003814 drug Substances 0.000 claims abstract description 4
- 238000002560 therapeutic procedure Methods 0.000 claims abstract description 4
- 108010019160 Pancreatin Proteins 0.000 claims abstract description 3
- 229940055695 pancreatin Drugs 0.000 claims abstract description 3
- 210000001186 vagus nerve Anatomy 0.000 claims abstract description 3
- 229940079593 drug Drugs 0.000 claims abstract 2
- 238000001802 infusion Methods 0.000 claims abstract 2
- 206010047700 Vomiting Diseases 0.000 claims description 5
- 230000008673 vomiting Effects 0.000 claims description 5
- 238000011084 recovery Methods 0.000 claims description 2
- 230000000306 recurrent effect Effects 0.000 claims description 2
- 238000013459 approach Methods 0.000 claims 1
- 238000002641 enzyme replacement therapy Methods 0.000 claims 1
- 230000002109 interictal effect Effects 0.000 claims 1
- 230000002035 prolonged effect Effects 0.000 claims 1
- CSCPPACGZOOCGX-UHFFFAOYSA-N Acetone Chemical compound CC(C)=O CSCPPACGZOOCGX-UHFFFAOYSA-N 0.000 description 2
- CIWBSHSKHKDKBQ-JLAZNSOCSA-N Ascorbic acid Chemical compound OC[C@H](O)[C@H]1OC(=O)C(O)=C1O CIWBSHSKHKDKBQ-JLAZNSOCSA-N 0.000 description 2
- UIIMBOGNXHQVGW-UHFFFAOYSA-M Sodium bicarbonate Chemical compound [Na+].OC([O-])=O UIIMBOGNXHQVGW-UHFFFAOYSA-M 0.000 description 2
- XQYZDYMELSJDRZ-UHFFFAOYSA-N papaverine Chemical compound C1=C(OC)C(OC)=CC=C1CC1=NC=CC2=CC(OC)=C(OC)C=C12 XQYZDYMELSJDRZ-UHFFFAOYSA-N 0.000 description 2
- 239000000243 solution Substances 0.000 description 2
- 229930008281 A03AD01 - Papaverine Natural products 0.000 description 1
- 208000004998 Abdominal Pain Diseases 0.000 description 1
- 229930003347 Atropine Natural products 0.000 description 1
- WQZGKKKJIJFFOK-GASJEMHNSA-N Glucose Natural products OC[C@H]1OC(O)[C@H](O)[C@@H](O)[C@@H]1O WQZGKKKJIJFFOK-GASJEMHNSA-N 0.000 description 1
- RKUNBYITZUJHSG-UHFFFAOYSA-N Hyosciamin-hydrochlorid Natural products CN1C(C2)CCC1CC2OC(=O)C(CO)C1=CC=CC=C1 RKUNBYITZUJHSG-UHFFFAOYSA-N 0.000 description 1
- 208000002193 Pain Diseases 0.000 description 1
- 206010037660 Pyrexia Diseases 0.000 description 1
- 210000001015 abdomen Anatomy 0.000 description 1
- 239000011668 ascorbic acid Substances 0.000 description 1
- 229960005070 ascorbic acid Drugs 0.000 description 1
- 235000010323 ascorbic acid Nutrition 0.000 description 1
- RKUNBYITZUJHSG-SPUOUPEWSA-N atropine Chemical compound O([C@H]1C[C@H]2CC[C@@H](C1)N2C)C(=O)C(CO)C1=CC=CC=C1 RKUNBYITZUJHSG-SPUOUPEWSA-N 0.000 description 1
- 229960000396 atropine Drugs 0.000 description 1
- 210000003451 celiac plexus Anatomy 0.000 description 1
- 229950001485 cocarboxylase Drugs 0.000 description 1
- 230000000052 comparative effect Effects 0.000 description 1
- 125000004122 cyclic group Chemical group 0.000 description 1
- 230000003247 decreasing effect Effects 0.000 description 1
- 238000003745 diagnosis Methods 0.000 description 1
- 230000037213 diet Effects 0.000 description 1
- 235000005911 diet Nutrition 0.000 description 1
- PCHPORCSPXIHLZ-UHFFFAOYSA-N diphenhydramine hydrochloride Chemical compound [Cl-].C=1C=CC=CC=1C(OCC[NH+](C)C)C1=CC=CC=C1 PCHPORCSPXIHLZ-UHFFFAOYSA-N 0.000 description 1
- 238000001962 electrophoresis Methods 0.000 description 1
- 239000008103 glucose Substances 0.000 description 1
- 230000035987 intoxication Effects 0.000 description 1
- 231100000566 intoxication Toxicity 0.000 description 1
- 238000007918 intramuscular administration Methods 0.000 description 1
- 210000004185 liver Anatomy 0.000 description 1
- 229940053973 novocaine Drugs 0.000 description 1
- 235000016709 nutrition Nutrition 0.000 description 1
- 230000035764 nutrition Effects 0.000 description 1
- 229960001789 papaverine Drugs 0.000 description 1
- 230000001314 paroxysmal effect Effects 0.000 description 1
- 230000001717 pathogenic effect Effects 0.000 description 1
- 239000002504 physiological saline solution Substances 0.000 description 1
- MFDFERRIHVXMIY-UHFFFAOYSA-N procaine Chemical compound CCN(CC)CCOC(=O)C1=CC=C(N)C=C1 MFDFERRIHVXMIY-UHFFFAOYSA-N 0.000 description 1
- 229910000030 sodium bicarbonate Inorganic materials 0.000 description 1
- 235000017557 sodium bicarbonate Nutrition 0.000 description 1
- YXVCLPJQTZXJLH-UHFFFAOYSA-N thiamine(1+) diphosphate chloride Chemical compound [Cl-].CC1=C(CCOP(O)(=O)OP(O)(O)=O)SC=[N+]1CC1=CN=C(C)N=C1N YXVCLPJQTZXJLH-UHFFFAOYSA-N 0.000 description 1
Landscapes
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Abstract
Изобретение относитс к медицине, в частности к педиатрии. Цель - предупреждение рецидивов заболевани . Дл этого нар ду с проведением инфузионной терапии ввод т лекарственные средства, обеспечивающие медикаментозную блокаду блуждающего нерва, в сочетании с панкреатином.This invention relates to medicine, in particular to pediatrics. The goal is to prevent the recurrence of the disease. To this end, along with conducting infusion therapy, drugs are introduced to ensure the medical blockade of the vagus nerve, in combination with pancreatin.
Description
Изобретение относитс к медицине, в частности педиатрии.This invention relates to medicine, in particular pediatrics.
Цель изобретени - предупреждение рецидивов заболевани .The purpose of the invention is to prevent the recurrence of the disease.
Пример. Больной И., 9 лет, поступил с жалобами на периодически возникающую приступообразную боль в животе, сопровождающуюс неукротимой рвотой, с запахом ацетона изо рта, повышением температуры тела.Example. Patient I., 9 years old, was admitted with complaints of recurrent paroxysmal pain in the abdomen, accompanied by indomitable vomiting, with the smell of acetone from the mouth, fever.
Из анамнеза известно, что указанные состо ни , провоцируемые погрешностью в питании, наблюдаетс у ребенка с 4-летнего возраста. Диагноз - периодическа ацето- немическа рвота.From the anamnesis, it is known that these conditions, provoked by an error in nutrition, are observed in a child from 4 years of age. The diagnosis is periodic acetonomic vomiting.
Лечение: диета, 1-2 день пищева разгрузка , далее стол 5, протертый вариант.Treatment: diet, 1-2 days food discharge, then table 5, wiped option.
С первого дн пищевой разгрузки назначены в/в 10% раствор глюкозы, физиологический раствор, 4% раствор бикарбоната натри , аскорбинова кислота, кокарбоксилаза, с одновременным в/м введением атропина, димедрола, папаверина в сочетании с электрофорезом с 2%-ным раствором новокаина на солнечное сплетение по общеприн той схеме, обеспечивающиеFrom the first day of food discharge, 10% glucose solution, physiological saline solution, 4% sodium bicarbonate solution, ascorbic acid, cocarboxylase, with simultaneous intramuscular administration of atropine, dimedrol, papaverine in combination with electrophoresis with 2% novocaine were prescribed; on the solar plexus according to the standard scheme, providing
медикаментозную блокаду блуждающего нерва,medical blockade of the vagus nerve,
С третьего дн лечени введен панкреатин , последний - в возрастной дозировке.From the third day of treatment, pancreatin was administered, the last one in the age dosage.
Под вли нием проводимой терапии исчезли признаки интоксикации, прекратилась рвота, к 3 дню уменьшилась, а к 7 дню полностью исчезла боль в животе.Under the influence of the therapy, the signs of intoxication disappeared, vomiting stopped, decreased to 3 days, and by the 7th day abdominal pain disappeared.
Наблюдение за ребенком в течение 5 лет не вы вило рецидива заболевани .Observation of the child for 5 years did not reveal the recurrence of the disease.
Проведено лечение 31 больного с ацето- немической рвотой.31 patients were treated with acetonemic vomiting.
Катамнестическое наблюдение за детьми в динамике 5 и более лет свидетельствовало об отсутствии цикличности в манифестации клинической картины заболевани и выздоровлении в 80% наблюдений.Follow-up observation of children over 5 and more years testified to the absence of cyclicity in the manifestation of the clinical picture of the disease and recovery in 80% of observations.
Сравнительна характеристика эффективности печени ацетонемической рвоты известными и предлагаемым методами представлена в таблице.A comparative characteristic of the efficacy of an acetonemic vomiting liver by the known and proposed methods is presented in the table.
Предлагаемый способ лечени позвол ет сократить сроки приступного периода в среднем от 3-4 до 1-2 дней.The proposed method of treatment can reduce the time of the onset period from an average of 3-4 to 1-2 days.
Используемый метод терапии вл етс патогенетическим и может быть рекомендован дл лечени циклической ацетонемиче-гThe method of therapy used is pathogenetic and can be recommended for the treatment of cyclic acetonemic-g
ЁYo
ОABOUT
ЈJ
GJ hO ОGJ hO About
ской рвоты различной природы как монопатогенетического процесса при известной его полиэтиологичности.vomiting of different nature as a monopathogenetic process with its known polyetiology.
Claims (1)
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| SU884425756A SU1664326A1 (en) | 1988-04-04 | 1988-04-04 | Method for treating periodic acetonemic vomiting of children |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| SU884425756A SU1664326A1 (en) | 1988-04-04 | 1988-04-04 | Method for treating periodic acetonemic vomiting of children |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| SU1664326A1 true SU1664326A1 (en) | 1991-07-23 |
Family
ID=21375162
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| SU884425756A SU1664326A1 (en) | 1988-04-04 | 1988-04-04 | Method for treating periodic acetonemic vomiting of children |
Country Status (1)
| Country | Link |
|---|---|
| SU (1) | SU1664326A1 (en) |
-
1988
- 1988-04-04 SU SU884425756A patent/SU1664326A1/en active
Non-Patent Citations (1)
| Title |
|---|
| Сидельников В.М. и др. Неотложные состо ни у детей, - К.: Здоровье, 1983, с. 153. * |
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