SU1446526A1 - Method of determining the degree of destruction in acute appendicitis cases - Google Patents
Method of determining the degree of destruction in acute appendicitis cases Download PDFInfo
- Publication number
- SU1446526A1 SU1446526A1 SU864081515A SU4081515A SU1446526A1 SU 1446526 A1 SU1446526 A1 SU 1446526A1 SU 864081515 A SU864081515 A SU 864081515A SU 4081515 A SU4081515 A SU 4081515A SU 1446526 A1 SU1446526 A1 SU 1446526A1
- Authority
- SU
- USSR - Soviet Union
- Prior art keywords
- acute appendicitis
- degree
- alkaline phosphatase
- peroxidase
- destruction
- Prior art date
Links
- 238000000034 method Methods 0.000 title claims abstract description 10
- 206010003011 Appendicitis Diseases 0.000 title claims abstract description 6
- 230000006378 damage Effects 0.000 title claims description 3
- 102000002260 Alkaline Phosphatase Human genes 0.000 claims abstract description 10
- 108020004774 Alkaline Phosphatase Proteins 0.000 claims abstract description 10
- 102000003992 Peroxidases Human genes 0.000 claims abstract description 9
- 108040007629 peroxidase activity proteins Proteins 0.000 claims abstract description 9
- 210000000265 leukocyte Anatomy 0.000 claims description 3
- 230000001965 increasing effect Effects 0.000 claims 1
- 230000002159 abnormal effect Effects 0.000 abstract description 2
- 230000000093 cytochemical effect Effects 0.000 abstract description 2
- 238000003745 diagnosis Methods 0.000 abstract description 2
- 239000003814 drug Substances 0.000 abstract description 2
- 230000001066 destructive effect Effects 0.000 abstract 2
- 206010061218 Inflammation Diseases 0.000 abstract 1
- 230000004054 inflammatory process Effects 0.000 abstract 1
- 210000000440 neutrophil Anatomy 0.000 abstract 1
- 210000005259 peripheral blood Anatomy 0.000 abstract 1
- 239000011886 peripheral blood Substances 0.000 abstract 1
- 230000000694 effects Effects 0.000 description 2
- 206010062717 Increased upper airway secretion Diseases 0.000 description 1
- 229910019142 PO4 Inorganic materials 0.000 description 1
- 210000000805 cytoplasm Anatomy 0.000 description 1
- 239000008187 granular material Substances 0.000 description 1
- 208000026435 phlegm Diseases 0.000 description 1
- NBIIXXVUZAFLBC-UHFFFAOYSA-K phosphate Chemical compound [O-]P([O-])([O-])=O NBIIXXVUZAFLBC-UHFFFAOYSA-K 0.000 description 1
- 239000010452 phosphate Substances 0.000 description 1
Landscapes
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
Abstract
Изобретение относитс к медицине и касаетс способа диагностики декструктивных форм острого аппендицита . Цель изобретени - повьппение точности диагностики острого аппендицита и определение степени деструктивного процесса. Дл этого определ ют щелочную фосфатазу и пероксида- зу в нейтрофилах периферической крови с вычислением среднего цитохимического коэффициента и по отклонению от нормы щелочной фосфатазы и перо- ксидазы до 191-209% и 17-19% соответственно суд т о наличии гангренозной формы воспалени , а до 268-282% и 30-32% - о гангренозно-перфоративной форме.This invention relates to medicine and concerns a method for diagnosing destructive forms of acute appendicitis. The purpose of the invention is to improve the accuracy of diagnosis of acute appendicitis and determine the degree of the destructive process. To do this, alkaline phosphatase and peroxidase in peripheral blood neutrophils are determined by calculating the average cytochemical coefficient and, by abnormal alkaline phosphatase and peroxidase, up to 191–209% and 17–19%, respectively, the presence of a gangrenous form of inflammation, and up to 268-282% and 30-32% - about the gangrenous-perforative form.
Description
Изобретение относитс к медицине И касаетс способов диагностики де-г структивных форм острого аппендицитаThe invention relates to medicine and concerns methods for the diagnosis of de-g structural forms of acute appendicitis.
Цепью изобретени вл етс повышение точности способа.The chain of the invention is to improve the accuracy of the method.
Способ осуществл ют следующим образом.The method is carried out as follows.
Исследуют щелочную фосфатазу (ЩФ) и пероксидазу (ПО) по известным мето дам в лейкоцитах с вычислением среднего цитохимического коэффициента по известной формуле. По отклонению от нормы щелочной фосфатаэы до 191- 209%, пероксидазы до 17-19% суд т о наличии флегмозной формы, а по гиперферментации щелочной фосфата- зы до 268-282%, пероксидазы до 30- 32% - о гангренозной форме острого аппендицита. Щелочна фосфатаза .вы вл етс в цитоплазме в виде черного или темно-серого окрашивайи , пероксидаза - в виде коричневых гранул .Alkaline phosphatase (alkaline phosphatase) and peroxidase (PO) are investigated by known methods in leukocytes with calculation of the average cytochemical coefficient using the well-known formula. By abnormal alkaline phosphate up to 191-209%, peroxidase up to 17-19%, the presence of a phlegm form is judged, and by hyperfermentation alkaline phosphatase up to 268-282%, peroxidase up to 30-32% - about an acute appendicitis gangrenous form . Alkaline phosphatase. You are in the cytoplasm in the form of a black or dark gray color, peroxidase - in the form of brown granules.
Исследование активности ЩФ и ПО позвол ет с высокой степенью достоверности судить о наличии деструкции именно в червеобразном отростке, если активность ЩФ не ниже 191% и не вьпае 282% по отношению к норме, а ПО не ниже 17% и не вьппе 32% по отклонению от нормы,,The study of alkaline phosphatase and software activity allows a high degree of reliability to judge the presence of destruction in the vermiform process, if the alkaline phosphatase activity is not lower than 191% and not higher than 282% in relation to the norm, and software is not lower than 17% and not 32% by deviation from the norm ,,
Claims (1)
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| SU864081515A SU1446526A1 (en) | 1986-06-27 | 1986-06-27 | Method of determining the degree of destruction in acute appendicitis cases |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| SU864081515A SU1446526A1 (en) | 1986-06-27 | 1986-06-27 | Method of determining the degree of destruction in acute appendicitis cases |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| SU1446526A1 true SU1446526A1 (en) | 1988-12-23 |
Family
ID=21242911
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| SU864081515A SU1446526A1 (en) | 1986-06-27 | 1986-06-27 | Method of determining the degree of destruction in acute appendicitis cases |
Country Status (1)
| Country | Link |
|---|---|
| SU (1) | SU1446526A1 (en) |
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP3209804A4 (en) * | 2014-10-22 | 2018-02-28 | The George Washington University A Congretionally Chartered Not-For-Profit Corp. | Blood biomarkers for appendicitis and diagnostics methods using biomarkers |
| US11629383B2 (en) | 2015-01-12 | 2023-04-18 | The George Washington University a Congressionally Chartered Not-for-Profit Corporation | Blood biomarkers for respiratory infections |
-
1986
- 1986-06-27 SU SU864081515A patent/SU1446526A1/en active
Non-Patent Citations (1)
| Title |
|---|
| Мат шин И.М, О пользе единой доктрины в неотложной хирургии. - Клиническа хирурги , 1978, № 4, с.1-9. * |
Cited By (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP3209804A4 (en) * | 2014-10-22 | 2018-02-28 | The George Washington University A Congretionally Chartered Not-For-Profit Corp. | Blood biomarkers for appendicitis and diagnostics methods using biomarkers |
| EP3502271A2 (en) * | 2014-10-22 | 2019-06-26 | The George Washington University, A Congressionally Chartered Not-For-Profit Corporation | Blood biomarkers for appendicitis and diagnostics methods using biomarkers |
| US11066706B2 (en) | 2014-10-22 | 2021-07-20 | The George Washington University, A Congressionally Chartered Not-For-Profit Corporation | Blood biomarkers for appendicitis and diagnostics methods using biomarkers |
| US11371096B2 (en) | 2014-10-22 | 2022-06-28 | The George Washington University a Congressionally Chartered Not-for-Profit Corporation | Blood biomarkers for appendicitis and diagnostics methods using biomarkers |
| US12215386B2 (en) | 2014-10-22 | 2025-02-04 | The George Washington University | Blood biomarkers for appendicitis and diagnostics methods using biomarkers |
| US11629383B2 (en) | 2015-01-12 | 2023-04-18 | The George Washington University a Congressionally Chartered Not-for-Profit Corporation | Blood biomarkers for respiratory infections |
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