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SMT202000466T1 - Scaffold di innesto per la riparazione di una cartilagine e processo per produrre il medesimo - Google Patents

Scaffold di innesto per la riparazione di una cartilagine e processo per produrre il medesimo

Info

Publication number
SMT202000466T1
SMT202000466T1 SM20200466T SMT202000466T SMT202000466T1 SM T202000466 T1 SMT202000466 T1 SM T202000466T1 SM 20200466 T SM20200466 T SM 20200466T SM T202000466 T SMT202000466 T SM T202000466T SM T202000466 T1 SMT202000466 T1 SM T202000466T1
Authority
SM
San Marino
Prior art keywords
making same
cartilage repair
graft scaffold
scaffold
graft
Prior art date
Application number
SM20200466T
Other languages
English (en)
Inventor
Marcy Zenobi-Wong
Matti Kesti
Michael Müller
Original Assignee
Eth Zuerich
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Eth Zuerich filed Critical Eth Zuerich
Publication of SMT202000466T1 publication Critical patent/SMT202000466T1/it

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/14—Macromolecular materials
    • A61L27/20—Polysaccharides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/14—Macromolecular materials
    • A61L27/26—Mixtures of macromolecular compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/36—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix
    • A61L27/3604—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix characterised by the human or animal origin of the biological material, e.g. hair, fascia, fish scales, silk, shellac, pericardium, pleura, renal tissue, amniotic membrane, parenchymal tissue, fetal tissue, muscle tissue, fat tissue, enamel
    • A61L27/3612—Cartilage, synovial fluid
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/36—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix
    • A61L27/38—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix containing added animal cells
    • A61L27/3804—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix containing added animal cells characterised by specific cells or progenitors thereof, e.g. fibroblasts, connective tissue cells, kidney cells
    • A61L27/3817—Cartilage-forming cells, e.g. pre-chondrocytes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/36—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix
    • A61L27/38—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix containing added animal cells
    • A61L27/3839—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix containing added animal cells characterised by the site of application in the body
    • A61L27/3843—Connective tissue
    • A61L27/3852—Cartilage, e.g. meniscus
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/36—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix
    • A61L27/38—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix containing added animal cells
    • A61L27/3839—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix containing added animal cells characterised by the site of application in the body
    • A61L27/3843—Connective tissue
    • A61L27/3852—Cartilage, e.g. meniscus
    • A61L27/3856—Intervertebral discs
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/40—Composite materials, i.e. containing one material dispersed in a matrix of the same or different material
    • A61L27/44—Composite materials, i.e. containing one material dispersed in a matrix of the same or different material having a macromolecular matrix
    • A61L27/46—Composite materials, i.e. containing one material dispersed in a matrix of the same or different material having a macromolecular matrix with phosphorus-containing inorganic fillers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/40—Composite materials, i.e. containing one material dispersed in a matrix of the same or different material
    • A61L27/44—Composite materials, i.e. containing one material dispersed in a matrix of the same or different material having a macromolecular matrix
    • A61L27/48—Composite materials, i.e. containing one material dispersed in a matrix of the same or different material having a macromolecular matrix with macromolecular fillers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/50—Materials characterised by their function or physical properties, e.g. injectable or lubricating compositions, shape-memory materials, surface modified materials
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/50—Materials characterised by their function or physical properties, e.g. injectable or lubricating compositions, shape-memory materials, surface modified materials
    • A61L27/52—Hydrogels or hydrocolloids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/50—Materials characterised by their function or physical properties, e.g. injectable or lubricating compositions, shape-memory materials, surface modified materials
    • A61L27/54—Biologically active materials, e.g. therapeutic substances
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B33—ADDITIVE MANUFACTURING TECHNOLOGY
    • B33Y—ADDITIVE MANUFACTURING, i.e. MANUFACTURING OF THREE-DIMENSIONAL [3-D] OBJECTS BY ADDITIVE DEPOSITION, ADDITIVE AGGLOMERATION OR ADDITIVE LAYERING, e.g. BY 3-D PRINTING, STEREOLITHOGRAPHY OR SELECTIVE LASER SINTERING
    • B33Y10/00—Processes of additive manufacturing
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B33—ADDITIVE MANUFACTURING TECHNOLOGY
    • B33Y—ADDITIVE MANUFACTURING, i.e. MANUFACTURING OF THREE-DIMENSIONAL [3-D] OBJECTS BY ADDITIVE DEPOSITION, ADDITIVE AGGLOMERATION OR ADDITIVE LAYERING, e.g. BY 3-D PRINTING, STEREOLITHOGRAPHY OR SELECTIVE LASER SINTERING
    • B33Y30/00—Apparatus for additive manufacturing; Details thereof or accessories therefor
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B33—ADDITIVE MANUFACTURING TECHNOLOGY
    • B33Y—ADDITIVE MANUFACTURING, i.e. MANUFACTURING OF THREE-DIMENSIONAL [3-D] OBJECTS BY ADDITIVE DEPOSITION, ADDITIVE AGGLOMERATION OR ADDITIVE LAYERING, e.g. BY 3-D PRINTING, STEREOLITHOGRAPHY OR SELECTIVE LASER SINTERING
    • B33Y70/00—Materials specially adapted for additive manufacturing
    • B33Y70/10—Composites of different types of material, e.g. mixtures of ceramics and polymers or mixtures of metals and biomaterials
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B33—ADDITIVE MANUFACTURING TECHNOLOGY
    • B33Y—ADDITIVE MANUFACTURING, i.e. MANUFACTURING OF THREE-DIMENSIONAL [3-D] OBJECTS BY ADDITIVE DEPOSITION, ADDITIVE AGGLOMERATION OR ADDITIVE LAYERING, e.g. BY 3-D PRINTING, STEREOLITHOGRAPHY OR SELECTIVE LASER SINTERING
    • B33Y80/00—Products made by additive manufacturing
    • G—PHYSICS
    • G05—CONTROLLING; REGULATING
    • G05B—CONTROL OR REGULATING SYSTEMS IN GENERAL; FUNCTIONAL ELEMENTS OF SUCH SYSTEMS; MONITORING OR TESTING ARRANGEMENTS FOR SUCH SYSTEMS OR ELEMENTS
    • G05B19/00—Programme-control systems
    • G05B19/02—Programme-control systems electric
    • G05B19/18—Numerical control [NC], i.e. automatically operating machines, in particular machine tools, e.g. in a manufacturing environment, so as to execute positioning, movement or co-ordinated operations by means of programme data in numerical form
    • G05B19/4097—Numerical control [NC], i.e. automatically operating machines, in particular machine tools, e.g. in a manufacturing environment, so as to execute positioning, movement or co-ordinated operations by means of programme data in numerical form characterised by using design data to control NC machines, e.g. CAD/CAM
    • G05B19/4099—Surface or curve machining, making 3D objects, e.g. desktop manufacturing
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2300/00—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
    • A61L2300/40—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices characterised by a specific therapeutic activity or mode of action
    • A61L2300/412—Tissue-regenerating or healing or proliferative agents
    • A61L2300/414—Growth factors
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2430/00—Materials or treatment for tissue regeneration
    • A61L2430/06—Materials or treatment for tissue regeneration for cartilage reconstruction, e.g. meniscus
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B33—ADDITIVE MANUFACTURING TECHNOLOGY
    • B33Y—ADDITIVE MANUFACTURING, i.e. MANUFACTURING OF THREE-DIMENSIONAL [3-D] OBJECTS BY ADDITIVE DEPOSITION, ADDITIVE AGGLOMERATION OR ADDITIVE LAYERING, e.g. BY 3-D PRINTING, STEREOLITHOGRAPHY OR SELECTIVE LASER SINTERING
    • B33Y50/00—Data acquisition or data processing for additive manufacturing
    • B33Y50/02—Data acquisition or data processing for additive manufacturing for controlling or regulating additive manufacturing processes
    • G—PHYSICS
    • G05—CONTROLLING; REGULATING
    • G05B—CONTROL OR REGULATING SYSTEMS IN GENERAL; FUNCTIONAL ELEMENTS OF SUCH SYSTEMS; MONITORING OR TESTING ARRANGEMENTS FOR SUCH SYSTEMS OR ELEMENTS
    • G05B2219/00—Program-control systems
    • G05B2219/30—Nc systems
    • G05B2219/35—Nc in input of data, input till input file format
    • G05B2219/35134—3-D cad-cam
    • G—PHYSICS
    • G05—CONTROLLING; REGULATING
    • G05B—CONTROL OR REGULATING SYSTEMS IN GENERAL; FUNCTIONAL ELEMENTS OF SUCH SYSTEMS; MONITORING OR TESTING ARRANGEMENTS FOR SUCH SYSTEMS OR ELEMENTS
    • G05B2219/00—Program-control systems
    • G05B2219/30—Nc systems
    • G05B2219/49—Nc machine tool, till multiple
    • G05B2219/49007—Making, forming 3-D object, model, surface

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Biomedical Technology (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Dermatology (AREA)
  • Oral & Maxillofacial Surgery (AREA)
  • Transplantation (AREA)
  • Materials Engineering (AREA)
  • Manufacturing & Machinery (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Cell Biology (AREA)
  • Botany (AREA)
  • Zoology (AREA)
  • Composite Materials (AREA)
  • Molecular Biology (AREA)
  • Urology & Nephrology (AREA)
  • Vascular Medicine (AREA)
  • Rheumatology (AREA)
  • Inorganic Chemistry (AREA)
  • Structural Engineering (AREA)
  • Ceramic Engineering (AREA)
  • Civil Engineering (AREA)
  • Dispersion Chemistry (AREA)
  • Automation & Control Theory (AREA)
  • General Physics & Mathematics (AREA)
  • Physics & Mathematics (AREA)
  • Human Computer Interaction (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Materials For Medical Uses (AREA)
  • Prostheses (AREA)
  • Polymers & Plastics (AREA)
  • Organic Chemistry (AREA)
  • Coating Apparatus (AREA)
SM20200466T 2014-12-11 2015-12-11 Scaffold di innesto per la riparazione di una cartilagine e processo per produrre il medesimo SMT202000466T1 (it)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
EP14197449 2014-12-11
EP15158224 2015-03-09
EP15817126.4A EP3230044B1 (en) 2014-12-11 2015-12-11 Graft scaffold for cartilage repair and process for making same
PCT/EP2015/079502 WO2016092106A1 (en) 2014-12-11 2015-12-11 Graft scaffold for cartilage repair and process for making same

Publications (1)

Publication Number Publication Date
SMT202000466T1 true SMT202000466T1 (it) 2020-11-10

Family

ID=55027702

Family Applications (1)

Application Number Title Priority Date Filing Date
SM20200466T SMT202000466T1 (it) 2014-12-11 2015-12-11 Scaffold di innesto per la riparazione di una cartilagine e processo per produrre il medesimo

Country Status (19)

Country Link
US (4) US10532126B2 (it)
EP (2) EP3230044B1 (it)
JP (1) JP6762936B2 (it)
CN (1) CN106999635B (it)
AU (1) AU2015359286B2 (it)
CA (1) CA2967162C (it)
CY (1) CY1123170T1 (it)
DK (2) DK3230044T3 (it)
ES (1) ES2809457T3 (it)
HR (1) HRP20201252T1 (it)
HU (1) HUE050420T2 (it)
IL (1) IL252771B (it)
LT (1) LT3230044T (it)
PL (1) PL3230044T3 (it)
PT (1) PT3230044T (it)
RS (1) RS60700B1 (it)
SI (1) SI3230044T1 (it)
SM (1) SMT202000466T1 (it)
WO (1) WO2016092106A1 (it)

Families Citing this family (80)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
PL3233493T3 (pl) 2014-12-18 2021-12-13 Cellink Ab Celulozowy biotusz nanowłóknisty do biodrukowania 3d do zastosowań w hodowaniu komórek, inżynierii tkankowej i medycynie regeneracyjnej
US11052175B2 (en) 2015-08-19 2021-07-06 Musculoskeletal Transplant Foundation Cartilage-derived implants and methods of making and using same
KR20190028433A (ko) 2016-06-16 2019-03-18 애스펙트 바이오시스템즈 리미티드 바이오프린팅된 반월판 임플란트 및 이를 사용하는 방법
EP3526007A4 (en) * 2016-10-12 2020-05-27 Advanced Biomatrix, Inc. THREE-DIMENSIONAL (3-D) PRINTING INKS MANUFACTURED FROM NATURAL EXTRACELLULAR MATRIX MOLECULES
CN106620873A (zh) * 2016-11-17 2017-05-10 太原理工大学 一种复合水凝胶软骨修复材料及其制备方法
US20180193522A1 (en) * 2016-12-23 2018-07-12 Lifecell Corporation Injectable hydrogels and applications thereof
CN106727706A (zh) * 2016-12-26 2017-05-31 湖南新起源医疗技术有限公司 一种用于皮肤损伤修复的细胞制剂的制备方法
CN106943632A (zh) * 2017-03-23 2017-07-14 江南大学 一种胶原/硫酸软骨素复合人工眼角膜及其制备方法
CN108686272B (zh) * 2017-03-29 2021-04-09 复旦大学附属华山医院 静电混纺肝素-瑞舒伐他汀钙壳芯结构纳米纤维动脉瘤覆膜支架及制备方法
EP3609956A4 (en) * 2017-04-10 2020-12-23 Thewell Bioscience HYDROGEL FOR BIOMEDICAL AND CELL CULTURE APPLICATIONS
KR102626745B1 (ko) 2017-05-26 2024-01-17 인피니트 머티리얼 솔루션즈, 엘엘씨 수용성 중합체 조성물
EP3427949B1 (en) * 2017-07-12 2024-10-09 MAPTECH Holdings UG Mechanically tunable bioinks for bioprinting
JP7057076B2 (ja) 2017-08-07 2022-04-19 株式会社クボタ 植物体の生産方法
CN107501612B (zh) * 2017-08-07 2020-04-28 华南理工大学 3d打印氧化石墨烯/纤维素复合材料及其制备方法与应用
US11643551B2 (en) * 2017-08-28 2023-05-09 Dsm Ip Assets B.V. Synthetic membrane composition comprising a polyurethane and a polyoxazoline
EP3697462B1 (en) 2017-10-19 2023-07-12 LifeCell Corporation Flowable acellular tissue matrix products and methods of production
US11246994B2 (en) 2017-10-19 2022-02-15 Lifecell Corporation Methods for introduction of flowable acellular tissue matrix products into a hand
US11485072B2 (en) 2017-10-27 2022-11-01 DePuy Synthes Products, Inc. Selective laser sintering of asymmetric particles
CN107823711B (zh) * 2017-11-09 2020-10-30 华中科技大学同济医学院附属协和医院 核壳结构复合材料的制备及利用其构建组织工程微组织的方法
EP3485918A1 (en) * 2017-11-21 2019-05-22 ETH Zürich Gel composition for 3d printing of cell suspensions
RU2020117360A (ru) * 2017-11-29 2021-12-29 Ореджен Байотерапьютикс Са Система стерильного аддитивного производства
WO2019126600A1 (en) * 2017-12-20 2019-06-27 Aspect Biosystems Ltd. Bioprinted meniscus implant and methods of using same
WO2019122351A1 (en) * 2017-12-22 2019-06-27 Cellink Ab Tissue-specific human bioinks for the physiological 3d-bioprinting of human tissues for in vitro culture and transplantation
CN108159500A (zh) * 2017-12-27 2018-06-15 天津宝坻紫荆科技有限公司 一种3d打印人工骨修复材料及其制备方法
WO2019145795A2 (en) 2018-01-26 2019-08-01 Cellink Ab Systems and methods for optical assessments of bioink printability
CN108355175A (zh) * 2018-02-12 2018-08-03 华中科技大学鄂州工业技术研究院 一种复合纳米纤维支架的制备方法
CN108187137A (zh) * 2018-02-27 2018-06-22 崔友军 一种可生物降解神经修复支架的制备方法
CN110240799A (zh) * 2018-03-09 2019-09-17 中国石油化工股份有限公司 3d打印组合物及其制备方法和应用
CN108578617B (zh) * 2018-04-09 2021-03-30 深圳市莱利赛生物科技有限公司 促进膝关节软骨再生用脐血间质干细胞药物的制备方法
CN108379659A (zh) * 2018-05-06 2018-08-10 西北工业大学 一种细胞密度多梯度人工软骨制备方法
CN108355168A (zh) * 2018-05-14 2018-08-03 上海交通大学医学院附属第九人民医院 一种结合三维打印技术制备髓核回植体的方法
CN108690205A (zh) * 2018-05-28 2018-10-23 深圳市第二人民医院 一种ⅱ型胶原和聚丙烯酰胺复合水凝胶及其制备和应用
CN108853582A (zh) * 2018-06-15 2018-11-23 南京冬尚生物科技有限公司 3D打印PCL-Cu骨组织工程支架及其制备方法
US20200040296A1 (en) * 2018-08-06 2020-02-06 University Of South Carolina Decellularized Tissue as a Microcarrier for Cell Culture and Expansion
US11426818B2 (en) 2018-08-10 2022-08-30 The Research Foundation for the State University Additive manufacturing processes and additively manufactured products
WO2020077118A1 (en) 2018-10-10 2020-04-16 Cellink Ab Double network bioinks
US20210001009A1 (en) * 2018-10-25 2021-01-07 Cellink Ab Biogum and botanical gum hydrogel bioinks for the physiological 3d bioprinting of tissue constructs for in vitro culture and transplantation
CN109432501A (zh) * 2018-10-30 2019-03-08 上海交通大学医学院附属第九人民医院 复合纤维支架在制备鼻整形的复合材料中的用途
CN109513037B (zh) * 2018-11-14 2021-09-17 华中科技大学同济医学院附属协和医院 一种负载介孔生物玻璃的小肠粘膜下层创面敷料
CN109248009B (zh) * 2018-11-23 2020-01-14 吉林大学 一种利用3d打印技术制作人工胸骨的方法
KR102302770B1 (ko) * 2018-11-30 2021-09-16 주식회사 엘앤씨바이오 인체 유래 성분을 함유하고 조직 특이적 세포 분화 효과를 갖는 3d 프린팅 바이오 잉크 조성물 및 그 제조방법
KR102098134B1 (ko) * 2019-02-13 2020-04-08 성균관대학교산학협력단 나노 섬유질 콜라겐 3차원 구조체 제조방법
JP7319382B2 (ja) * 2019-03-11 2023-08-01 ロキット ヘルスケア インク． 凍結乾燥硝子軟骨パウダーを用いた軟骨再生用組成物の製造方法、これを用いて製造された軟骨再生用組成物、軟骨再生用組成物を用いた患者オーダーメード型軟骨再生用スキャフォールドの製造方法及び患者オーダーメード型軟骨再生用スキャフォールド
WO2020205645A1 (en) * 2019-03-29 2020-10-08 Tdbt Ip Inc. Tissue and organ replacements and methods of making thereof
KR20210146376A (ko) * 2019-03-29 2021-12-03 이노베이티브 올쏘피딕스, 엘엘씨 연골 대체 조성물 및 방법
CN110331124B (zh) * 2019-06-14 2022-03-22 浙江大学 一种导电聚吡咯/细胞外基质复合薄膜及其制备方法
CN110464879A (zh) * 2019-07-15 2019-11-19 暨南大学 一种骨组织工程支架的3d打印方法
CN110302428B (zh) * 2019-07-30 2021-07-13 中国人民解放军陆军军医大学第一附属医院 基于活细胞3d打印的软骨-骨-骨髓复合组织结构及方法
CN110538006B (zh) * 2019-08-13 2022-06-17 上海亚朋生物技术有限公司 纤维增强的三维打印软骨脱细胞基质支架的制作方法
CN110433331B (zh) * 2019-08-26 2021-08-24 四川大学 一种生物活性支架及其制备方法
CN110450401A (zh) * 2019-09-05 2019-11-15 上海交通大学医学院附属第九人民医院 一种液体支撑介质内生物三维打印人工关节的方法
US11826951B2 (en) 2019-09-06 2023-11-28 Cellink Ab Temperature-controlled multi-material overprinting
CN110478529A (zh) * 2019-09-24 2019-11-22 广西医科大学 一种3d打印魔芋胶水凝胶支架及制备方法和应用
WO2021077091A1 (en) 2019-10-18 2021-04-22 Carnegie Mellon University Modification of rheology and machine pathing for improved 3d printing of soft materials
CN110575568A (zh) * 2019-10-22 2019-12-17 上海交通大学医学院附属第九人民医院 一种用于3d打印的水凝胶材料、制备方法及用途
CN110680954A (zh) * 2019-11-06 2020-01-14 广西医科大学 一种3d打印黄原胶水凝胶支架及其制备方法
CN110755685A (zh) * 2019-11-06 2020-02-07 广西医科大学 一种3d打印瓜尔胶水凝胶支架及其制备方法
KR102228619B1 (ko) * 2019-11-25 2021-03-17 경희대학교 산학협력단 히알루론산 및 폴리에틸렌글리콜을 포함하여 제조된 세포 시트 및 이의 제조방법
KR20220116194A (ko) * 2019-12-18 2022-08-22 그리폴즈 월드와이드 오퍼레이션스 리미티드 골 복합체 및 이를 제조하기 위한 조성물
CN111320767B (zh) * 2020-03-04 2023-01-10 西南交通大学 一种用于3d生物打印的可触变性水凝胶的制备方法
CN114080244A (zh) * 2020-03-06 2022-02-22 爱恩斯生物科技(昆山)有限公司 利用基于软骨成分的生物墨水的治疗小耳症目的结构体制造用组合物及其制造方法
US12371581B2 (en) 2020-03-25 2025-07-29 Infinite Material Solutions, Llc High performance water soluble polymer compositions
EP4130235A4 (en) * 2020-03-26 2024-07-10 Osaka University SUPPORT BATH FOR THREE-DIMENSIONAL (3D) TISSUE CULTURE
CN113456897A (zh) * 2020-03-31 2021-10-01 威斯顿股份有限公司 生物材料及其用于促进组织再生的用途
KR20230025788A (ko) * 2020-06-17 2023-02-23 아우레겐 바이오테라퓨틱스 에스에이 성숙된 3차원 프린트된 조성물 및 이의 용도
CN112354017B (zh) * 2020-11-19 2022-07-26 中国医学科学院生物医学工程研究所 一种3d打印的力学仿生耳廓软骨组织工程支架及其制造方法
EP4271325A4 (en) * 2021-01-04 2024-11-27 Technion Research & Development Foundation Limited Auricular reconstruction using 3d printed autologous cartilage tissue
WO2022176888A1 (ja) * 2021-02-16 2022-08-25 株式会社ニッピ バイオインク、成型体、製品、および成型体の製造方法
CN113069596A (zh) * 2021-04-07 2021-07-06 山东建筑大学 一种基于3d打印半月板的复合生物陶瓷修复材料
CN113244455B (zh) * 2021-05-17 2022-08-05 广西医科大学 一种3d打印亚麻籽水凝胶支架及制备方法和应用
CN118055953A (zh) 2021-06-16 2024-05-17 奥里根生物治疗公司 结冷胶组合物及其制备方法
JP2024522790A (ja) 2021-06-18 2024-06-21 ディメンション インクス コーポレイション 付加製造された自己ゲル化構造物の製造方法及びそれらの使用
WO2023247801A1 (en) * 2022-06-24 2023-12-28 Katholieke Universiteit Leuven Printing of cell aggregates
EP4549131A1 (en) * 2022-06-30 2025-05-07 Osaka University Method for manufacturing three-dimensional object and ink set for manufacturing three-dimensional object
JPWO2024043039A1 (it) * 2022-08-26 2024-02-29
CN115519788B (zh) * 2022-09-06 2024-03-15 深圳先进技术研究院 组织工程支架的打印方法、打印系统、终端及存储介质
AU2023358774A1 (en) * 2022-10-13 2025-05-22 North Carolina State University Implantable scaffolds and methods of use
CN116139341B (zh) * 2022-12-14 2024-06-25 四川大学 一种定向冷冻聚乙烯醇/交联脱细胞基质复合材料及其制备方法和应用
CN116970304B (zh) * 2023-06-13 2025-02-14 华南理工大学 一种MnO2-蛋白纤维复合颗粒凝胶墨水及其制备与应用
WO2025070369A1 (ja) * 2023-09-25 2025-04-03 国立大学法人大阪大学 三次元造形物の製造方法および三次元造形物作製用インクセット

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6126690A (en) * 1996-07-03 2000-10-03 The Trustees Of Columbia University In The City Of New York Anatomically correct prosthesis and method and apparatus for manufacturing prosthesis
CA2602050C (en) * 2005-03-11 2013-12-03 Wake Forest University Health Sciences Production of tissue engineered heart valves
US7531503B2 (en) * 2005-03-11 2009-05-12 Wake Forest University Health Sciences Cell scaffold matrices with incorporated therapeutic agents
US20090117087A1 (en) * 2007-04-13 2009-05-07 Wake Forest University Methods and compositions for printing biologically compatible nanotube composites of autologous tissue
US9012415B2 (en) * 2010-03-26 2015-04-21 Stemmatters, Biotecnologia E Medicina Regenerativa S.A. Photo-crosslinked gellan gum-based hydrogels: preparation methods and uses thereof
US20120089238A1 (en) * 2010-10-06 2012-04-12 Hyun-Wook Kang Integrated organ and tissue printing methods, system and apparatus
WO2014032748A1 (en) * 2012-08-31 2014-03-06 Eth Zurich Process of cartilage repair
AU2013204780A1 (en) * 2013-04-12 2014-10-30 University Of Wollongong Formulation and Method

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