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SMT201900530T1 - A soluble chimeric interleukin-10 receptor and therapeutic use thereof - Google Patents

A soluble chimeric interleukin-10 receptor and therapeutic use thereof

Info

Publication number
SMT201900530T1
SMT201900530T1 SM20190530T SMT201900530T SMT201900530T1 SM T201900530 T1 SMT201900530 T1 SM T201900530T1 SM 20190530 T SM20190530 T SM 20190530T SM T201900530 T SMT201900530 T SM T201900530T SM T201900530 T1 SMT201900530 T1 SM T201900530T1
Authority
SM
San Marino
Prior art keywords
receptor
therapeutic use
soluble chimeric
chimeric interleukin
interleukin
Prior art date
Application number
SM20190530T
Other languages
Italian (it)
Inventor
Gilberto Filaci
Daniela Fenoglio
Francesca Ferrera
Original Assignee
Mediolanum Farm S P A
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Mediolanum Farm S P A filed Critical Mediolanum Farm S P A
Publication of SMT201900530T1 publication Critical patent/SMT201900530T1/en

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/52Cytokines; Lymphokines; Interferons
    • C07K14/54Interleukins [IL]
    • C07K14/5428IL-10
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • A61P37/02Immunomodulators
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/705Receptors; Cell surface antigens; Cell surface determinants
    • C07K14/715Receptors; Cell surface antigens; Cell surface determinants for cytokines; for lymphokines; for interferons
    • C07K14/7155Receptors; Cell surface antigens; Cell surface determinants for cytokines; for lymphokines; for interferons for interleukins [IL]
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/76Albumins
    • C07K14/765Serum albumin, e.g. HSA
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/50Immunoglobulins specific features characterized by immunoglobulin fragments
    • C07K2317/52Constant or Fc region; Isotype
    • C07K2317/53Hinge
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/60Immunoglobulins specific features characterized by non-natural combinations of immunoglobulin fragments
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2319/00Fusion polypeptide
    • C07K2319/31Fusion polypeptide fusions, other than Fc, for prolonged plasma life, e.g. albumin

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Toxicology (AREA)
  • Zoology (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Immunology (AREA)
  • Cell Biology (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Medicinal Preparation (AREA)
  • Epidemiology (AREA)
SM20190530T 2015-04-29 2016-04-26 A soluble chimeric interleukin-10 receptor and therapeutic use thereof SMT201900530T1 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
ITUB20150391 2015-04-29
EP16728097.3A EP3288965B1 (en) 2015-04-29 2016-04-26 A soluble chimeric interleukin-10 receptor and therapeutic use thereof
PCT/IB2016/052359 WO2016174575A1 (en) 2015-04-29 2016-04-26 A soluble chimeric interleukin-10 receptor and therapeutic use thereof

Publications (1)

Publication Number Publication Date
SMT201900530T1 true SMT201900530T1 (en) 2019-11-13

Family

ID=53765409

Family Applications (1)

Application Number Title Priority Date Filing Date
SM20190530T SMT201900530T1 (en) 2015-04-29 2016-04-26 A soluble chimeric interleukin-10 receptor and therapeutic use thereof

Country Status (16)

Country Link
US (1) US20180086809A1 (en)
EP (1) EP3288965B1 (en)
JP (1) JP2018518945A (en)
KR (1) KR20170138569A (en)
CN (1) CN107531771A (en)
CA (1) CA2979973A1 (en)
CY (1) CY1122061T1 (en)
DK (1) DK3288965T3 (en)
ES (1) ES2744342T3 (en)
HK (1) HK1245814B (en)
HU (1) HUE046343T2 (en)
PL (1) PL3288965T3 (en)
PT (1) PT3288965T (en)
SI (1) SI3288965T1 (en)
SM (1) SMT201900530T1 (en)
WO (1) WO2016174575A1 (en)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN118307682A (en) 2016-09-27 2024-07-09 埃皮辛特瑞柯斯公司 Immunomodulatory fusion protein
CA3077223A1 (en) * 2017-09-27 2019-04-04 Epicentrx, Inc. Immunomodulatory fusion proteins
EP3930687A4 (en) 2019-02-25 2023-06-07 The University of Chicago METHODS AND COMPOSITIONS FOR THE TREATMENT OF AUTOIMMUNE AND INFLAMMATORY DISEASES INVOLVING PEPTIDES WITH AN AFFINITY FOR THE EXTRACELLULAR MATRIX BONDED TO ANTI-INFLAMMATORY AGENTS
AU2021236879A1 (en) * 2020-03-16 2022-11-10 Vrije Universiteit Brussel A mixture of mRNA to enhance the potency of dendritic cells
CN116162149A (en) * 2022-12-06 2023-05-26 苏州绶草生物科技有限公司 A method for increasing the gene expression of synthetic recombinant human serum albumin in plants
CN116125074A (en) * 2022-12-13 2023-05-16 北京东方百泰生物科技股份有限公司 A method for detecting the binding activity of IL-10-Fc fusion protein and its receptor

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5789192A (en) * 1992-12-10 1998-08-04 Schering Corporation Mammalian receptors for interleukin-10 (IL-10)
US6165476A (en) * 1997-07-10 2000-12-26 Beth Israel Deaconess Medical Center Fusion proteins with an immunoglobulin hinge region linker
AU2001261024A1 (en) * 2000-04-12 2001-10-30 Delta Biotechnology Limited Albumin fusion proteins
JP4635255B2 (en) * 2003-09-02 2011-02-23 独立行政法人産業技術総合研究所 Antibody medicine
ES2438098T3 (en) * 2003-11-13 2014-01-15 Hanmi Science Co., Ltd. Pharmaceutical composition comprising an immunoglobulin Fc as a vehicle
ES2415604T3 (en) * 2007-05-30 2013-07-26 Postech Academy-Industry- Foundation Immunoglobulin Fusion Proteins
NO2344540T3 (en) * 2008-10-02 2018-04-28
ES2670442T3 (en) * 2012-05-25 2018-05-30 Janssen Biotech, Inc. Unnatural consensus albumin binding domains

Also Published As

Publication number Publication date
HK1245814B (en) 2020-06-19
CN107531771A (en) 2018-01-02
EP3288965A1 (en) 2018-03-07
JP2018518945A (en) 2018-07-19
PL3288965T3 (en) 2019-11-29
PT3288965T (en) 2019-10-15
SI3288965T1 (en) 2019-10-30
CA2979973A1 (en) 2016-11-03
US20180086809A1 (en) 2018-03-29
DK3288965T3 (en) 2019-09-23
EP3288965B1 (en) 2019-06-26
KR20170138569A (en) 2017-12-15
HUE046343T2 (en) 2020-02-28
WO2016174575A1 (en) 2016-11-03
ES2744342T3 (en) 2020-02-24
CY1122061T1 (en) 2020-11-25

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