SK46993A3 - New heterocyclic compounds as antagonists of excitatory amino acid receptors, process for their preparation and their use - Google Patents

New heterocyclic compounds as antagonists of excitatory amino acid receptors, process for their preparation and their use Download PDF

Info

Publication number: SK46993A3
Authority: SK; Slovakia
Prior art keywords: group; compounds; methylene; formula; carbon atoms
Prior art date: 1990-11-15

Application number

SK46993A

Other languages

English (en)

Slovak (sk)

Inventor

Alf Claesson

Britt-Marie Swahn

Original Assignee

Astra Ab

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1990-11-15

Filing date

1991-11-07

Publication date

1993-10-06

1991-11-07 Application filed by Astra Ab filed Critical Astra Ab

1993-10-06 Publication of SK46993A3 publication Critical patent/SK46993A3/sk

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
- C07F9/02—Phosphorus compounds
- C07F9/547—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom
- C07F9/645—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom having two nitrogen atoms as the only ring hetero atoms
- C07F9/6509—Six-membered rings
- C07F9/650952—Six-membered rings having the nitrogen atoms in the positions 1 and 4
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/04—Centrally acting analgesics, e.g. opioids
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/20—Hypnotics; Sedatives
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
- C07F9/02—Phosphorus compounds
- C07F9/547—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom
- C07F9/553—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom having one nitrogen atom as the only ring hetero atom
- C07F9/576—Six-membered rings
- C07F9/59—Hydrogenated pyridine rings

Landscapes

Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
General Health & Medical Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Chemical Kinetics & Catalysis (AREA)
Veterinary Medicine (AREA)
General Chemical & Material Sciences (AREA)
Medicinal Chemistry (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Public Health (AREA)
Pharmacology & Pharmacy (AREA)
Bioinformatics & Cheminformatics (AREA)
Animal Behavior & Ethology (AREA)
Engineering & Computer Science (AREA)
Biomedical Technology (AREA)
Neurology (AREA)
Neurosurgery (AREA)
Biochemistry (AREA)
Molecular Biology (AREA)
Cardiology (AREA)
Heart & Thoracic Surgery (AREA)
Anesthesiology (AREA)
Pain & Pain Management (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Injection Moulding Of Plastics Or The Like (AREA)
Plural Heterocyclic Compounds (AREA)

SK46993A 1990-11-15 1991-11-07 New heterocyclic compounds as antagonists of excitatory amino acid receptors, process for their preparation and their use SK46993A3 (en)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
SE9003652A SE9003652D0 (sv)	1990-11-15	1990-11-15	New heterocyclic compounds
PCT/SE1991/000753 WO1992008724A1 (fr)	1990-11-15	1991-11-07	Nouveaux composes heterocycliques utilises comme antagonistes de recepteurs d'acide amine excitateurs, procedes servant a leur preparation et leur utilisation

Publications (1)

Publication Number	Publication Date
SK46993A3 true SK46993A3 (en)	1993-10-06

Family

ID=20380925

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
SK46993A SK46993A3 (en)	1990-11-15	1991-11-07	New heterocyclic compounds as antagonists of excitatory amino acid receptors, process for their preparation and their use

Country Status (17)

Country	Link
EP (1)	EP0557375A1 (fr)
JP (1)	JPH06502421A (fr)
CN (1)	CN1061595A (fr)
AU (1)	AU652399B2 (fr)
CA (1)	CA2095224A1 (fr)
CZ (1)	CZ80993A3 (fr)
FI (1)	FI932206A7 (fr)
HU (1)	HU9301417D0 (fr)
IE (1)	IE913922A1 (fr)
IS (1)	IS3782A7 (fr)
LT (1)	LTIP1718A (fr)
MX (1)	MX9101979A (fr)
NO (1)	NO931679L (fr)
PT (1)	PT99515A (fr)
SE (1)	SE9003652D0 (fr)
SK (1)	SK46993A3 (fr)
WO (1)	WO1992008724A1 (fr)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US5194430A (en) *	1990-05-17	1993-03-16	Merrell Dow Pharmaceuticals Inc.	Heterocyclic-nmda antagonists
TW281670B (fr) *	1993-09-02	1996-07-21	Hoffmann La Roche
US5491241A (en) *	1993-10-18	1996-02-13	Eli Lilly And Company	Bicyclic intermediates for excitatory amino acid receptor antagonists
DK3984994T3 (da)	2016-02-04	2024-10-14	Takeda Pharmaceuticals Co	Substitueret piperidinforbindelse som orexin-type 2-agonist til behandling af narkolepsi

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
CA1248531A (fr) *	1984-04-17	1989-01-10	Jeffrey C. Watkins	Derives de substitution en 4 d'acides piperazine-2- carboxyliques
JPS612519A (ja) *	1984-04-24	1986-01-08	Aron Kasei Co Ltd	射出成形法
US4906621A (en) *	1985-05-24	1990-03-06	Ciba-Geigy Corporation	Certain 2-carboxypiperidyl-alkylene phosphonic acids and esters thereof useful for the treatment of disorders responsive to N-methyl-D-aspartate receptor blockade
US4740346A (en) *	1986-02-26	1988-04-26	The Budd Company	Perimeter resin feeding of composite structures
JPS63112129A (ja) *	1986-10-30	1988-05-17	Toyoda Gosei Co Ltd	多色樹脂成形用金型
IL84492A0 (en) *	1986-11-21	1988-04-29	Ciba Geigy Ag	Unsaturated phosphonic acids and derivatives

1990
- 1990-11-15 SE SE9003652A patent/SE9003652D0/xx unknown
1991
- 1991-11-05 CN CN91110925A patent/CN1061595A/zh active Pending
- 1991-11-07 JP JP4500566A patent/JPH06502421A/ja active Pending
- 1991-11-07 SK SK46993A patent/SK46993A3/sk unknown
- 1991-11-07 HU HU931417A patent/HU9301417D0/hu unknown
- 1991-11-07 CA CA002095224A patent/CA2095224A1/fr not_active Abandoned
- 1991-11-07 CZ CS93809A patent/CZ80993A3/cs unknown
- 1991-11-07 AU AU89391/91A patent/AU652399B2/en not_active Ceased
- 1991-11-07 WO PCT/SE1991/000753 patent/WO1992008724A1/fr not_active Ceased
- 1991-11-07 FI FI932206A patent/FI932206A7/fi not_active Application Discontinuation
- 1991-11-07 EP EP91920264A patent/EP0557375A1/fr not_active Withdrawn
- 1991-11-08 MX MX9101979A patent/MX9101979A/es unknown
- 1991-11-12 IE IE392291A patent/IE913922A1/en unknown
- 1991-11-14 PT PT99515A patent/PT99515A/pt not_active Application Discontinuation
- 1991-11-14 IS IS3782A patent/IS3782A7/is unknown
1993
- 1993-05-07 NO NO93931679A patent/NO931679L/no unknown
- 1993-12-30 LT LTIP1718A patent/LTIP1718A/xx not_active Application Discontinuation

Also Published As

Publication number	Publication date
FI932206L (fi)	1993-05-14
EP0557375A1 (fr)	1993-09-01
MX9101979A (es)	1992-07-08
FI932206A0 (fi)	1993-05-14
IS3782A7 (is)	1992-05-16
WO1992008724A1 (fr)	1992-05-29
IE913922A1 (en)	1992-05-20
AU8939191A (en)	1992-06-11
JPH06502421A (ja)	1994-03-17
HU9301417D0 (en)	1993-09-28
NO931679D0 (no)	1993-05-07
SE9003652D0 (sv)	1990-11-15
CZ80993A3 (en)	1994-02-16
LTIP1718A (en)	1995-07-25
NO931679L (no)	1993-05-07
CN1061595A (zh)	1992-06-03
CA2095224A1 (fr)	1992-05-16
PT99515A (pt)	1992-09-30
AU652399B2 (en)	1994-08-25
FI932206A7 (fi)	1993-05-14

Publication	Publication Date	Title
AT393384B (de)	1991-10-10	Substituierte alpha-aminosaeuren, ihre herstellung und diese enthaltende arzneimittel
EP0272208B1 (fr)	1991-06-12	Acides azacycloalkylalcanediphosphoniques substitués aromatiquement
SI9111099A (sl)	1998-02-28	Postopek za pripravo aralifatsko N-substituiranih aminoalkanfosfinskih kislin
HUT53879A (en)	1990-12-28	Improved process for producing decahydro-isoquinoline derivatives
EP0539057B1 (fr)	1997-07-16	Acides benzimidazole phosphono-aminés
DE69014697T2 (de)	1995-05-11	Tetrahydrobenz[c,d]indole als Serotonin-Agonisten.
EP0569333B1 (fr)	1999-01-07	Nouveaux acides N-aralkyl et N-hétéroaralkylamino alcane phosphoniques
DE3510858A1 (de)	1985-10-10	Substituierte (alpha)-aminosaeuren, verfahren zu deren herstellung und diese enthaltende arzneimittel
Hays et al.	1990	New and versatile approaches to the synthesis of CPP-related competitive NMDA antagonists. Preliminary structure activity relationships and pharmacological evaluation
SK46993A3 (en)	1993-10-06	New heterocyclic compounds as antagonists of excitatory amino acid receptors, process for their preparation and their use
EP0389425B1 (fr)	1995-04-26	Benzothiopyranylamines
EP0420806B1 (fr)	1995-07-05	Acides phosphoniques, procédé de préparation et utilisation comme composition pharmaceutique
US5489717A (en)	1996-02-06	Glutamate (NMDA) receptor antagonists
US5710139A (en)	1998-01-20	Heterocyclic compounds
DE69015745T2 (de)	1995-05-11	NMDA-Antagonisten.
DE69115116T2 (de)	1996-06-13	Heterocyclische NMDA Antagonisten.
DE69310524T2 (de)	1997-12-04	Phosphono substituierte tetrazol-derivate
US5500419A (en)	1996-03-19	NMDA antagonists
EP0213080A2 (fr)	1987-03-04	Dérivés hydrogénés de la pyridine
JPH02196723A (ja)	1990-08-03	リン含有酵素阻害剤