SK4202000A3 - Process of making 3-aryloxy-4-aryl furan-2-ones useful as inhibitors of cox-2 - Google Patents
Process of making 3-aryloxy-4-aryl furan-2-ones useful as inhibitors of cox-2 Download PDFInfo
- Publication number
- SK4202000A3 SK4202000A3 SK420-2000A SK4202000A SK4202000A3 SK 4202000 A3 SK4202000 A3 SK 4202000A3 SK 4202000 A SK4202000 A SK 4202000A SK 4202000 A3 SK4202000 A3 SK 4202000A3
- Authority
- SK
- Slovakia
- Prior art keywords
- compound
- formula
- group
- dhqd
- reacting
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
- C07D307/02—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings
- C07D307/34—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
- C07D307/56—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D307/60—Two oxygen atoms, e.g. succinic anhydride
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Furan Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Plural Heterocyclic Compounds (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US6069497P | 1997-09-24 | 1997-09-24 | |
| GBGB9815805.8A GB9815805D0 (en) | 1998-07-21 | 1998-07-21 | Chemical process |
| PCT/US1998/019642 WO1999015513A1 (fr) | 1997-09-24 | 1998-09-21 | Procede de preparation de 3-aryloxy, 4-aryl furan-2-ones utiles comme inhibiteurs de cox-2 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| SK4202000A3 true SK4202000A3 (en) | 2000-10-09 |
Family
ID=26314074
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| SK420-2000A SK4202000A3 (en) | 1997-09-24 | 1998-09-21 | Process of making 3-aryloxy-4-aryl furan-2-ones useful as inhibitors of cox-2 |
Country Status (7)
| Country | Link |
|---|---|
| EP (1) | EP1017687A4 (fr) |
| JP (1) | JP3516658B2 (fr) |
| CN (1) | CN1271352A (fr) |
| AU (1) | AU2247599A (fr) |
| EA (1) | EA002690B1 (fr) |
| SK (1) | SK4202000A3 (fr) |
| WO (1) | WO1999015513A1 (fr) |
Families Citing this family (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| BR0108908A (pt) | 2000-03-03 | 2002-12-24 | Pfizer Prod Inc | Derivados de éteres de pirazol como agentes antiinflamatórios/analgésicos |
| PT1303265E (pt) | 2000-07-20 | 2007-10-09 | Lauras As | ''utilização de inibidores da cox-2 como imuno-estimulantes, no tratamento do vih ou da sida'' |
| CN118164933B (zh) * | 2024-04-10 | 2025-04-08 | 辽宁中医药大学 | 马齿苋中一种呋喃类新化合物及其提取分离方法与用途 |
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5352832A (en) * | 1992-12-18 | 1994-10-04 | Schering Corporation | Asymmetric process for preparing florfenicol, thiamphenicol chloramphenicol and oxazoline intermediates |
| US5393790A (en) * | 1994-02-10 | 1995-02-28 | G.D. Searle & Co. | Substituted spiro compounds for the treatment of inflammation |
| UA57002C2 (uk) * | 1995-10-13 | 2003-06-16 | Мерк Фросст Кенада Енд Ко./Мерк Фросст Кенада Енд Сі. | Похідне (метилсульфоніл)феніл-2-(5н)-фуранону, фармацевтична композиція та спосіб лікування |
| US5789413A (en) * | 1996-02-01 | 1998-08-04 | Merck Frosst Canada, Inc. | Alkylated styrenes as prodrugs to COX-2 inhibitors |
-
1998
- 1998-09-21 SK SK420-2000A patent/SK4202000A3/sk unknown
- 1998-09-21 WO PCT/US1998/019642 patent/WO1999015513A1/fr not_active Ceased
- 1998-09-21 EP EP98947177A patent/EP1017687A4/fr not_active Withdrawn
- 1998-09-21 JP JP2000512820A patent/JP3516658B2/ja not_active Expired - Fee Related
- 1998-09-21 CN CN98809463A patent/CN1271352A/zh active Pending
- 1998-09-21 AU AU22475/99A patent/AU2247599A/en not_active Abandoned
- 1998-09-21 EA EA200000350A patent/EA002690B1/ru not_active IP Right Cessation
Also Published As
| Publication number | Publication date |
|---|---|
| EP1017687A1 (fr) | 2000-07-12 |
| EP1017687A4 (fr) | 2001-10-31 |
| WO1999015513A1 (fr) | 1999-04-01 |
| CN1271352A (zh) | 2000-10-25 |
| JP3516658B2 (ja) | 2004-04-05 |
| JP2001517661A (ja) | 2001-10-09 |
| EA002690B1 (ru) | 2002-08-29 |
| AU2247599A (en) | 1999-04-12 |
| EA200000350A1 (ru) | 2000-10-30 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| EP1626045B1 (fr) | Methodes de production de 2-chloro-5-fluoropyridine 3-substitue ou de son sel | |
| US6140515A (en) | Process of making 3-aryloxy, 4-aryl furan-2-ones useful as inhibitors of COX-2 | |
| JPH0529216B2 (fr) | ||
| JPH0414107B2 (fr) | ||
| CN120247782B (zh) | 氟吡菌酰胺类化合物及其制备方法 | |
| SK4202000A3 (en) | Process of making 3-aryloxy-4-aryl furan-2-ones useful as inhibitors of cox-2 | |
| KR20140009016A (ko) | 신규의 피리딘 유도체 및 이를 이용한 설포닐우레아 제초제의 제조 중간체 화합물의 제조방법 | |
| JP2001233870A (ja) | 3−(1−ヒドロキシ−ペンチリデン)−5−ニトロ−3h−ベンゾフラン−2−オン、その製造方法及びその用途 | |
| JP2771994B2 (ja) | プロペン酸誘導体の製造法 | |
| JP2022503397A (ja) | 高収率の血管漏出遮断薬の調製方法 | |
| JP7545696B2 (ja) | ピロリノン系化合物及びその合成方法 | |
| CN113563328B (zh) | 一种1,3-二取代-2-氟中氮茚衍生物的制备方法 | |
| KR102674919B1 (ko) | 3-브로모-5-(2-에틸이미다조[1,2-a]피리딘-3-카르보닐)-2-하이드록시벤조니트릴의 합성 | |
| JPH02289563A (ja) | o―カルボキシピリジル―およびo―カルボキシキノリルイミダゾリノンの改良製造法 | |
| JP2003511444A (ja) | Cox−2抑制剤の製造方法 | |
| CZ20001087A3 (cs) | Způsob výroby furan-2-onovýdi derivátů | |
| KR20200082424A (ko) | 로잘탄 대사체 exp-3174의 제조방법 | |
| JP2743198B2 (ja) | シクロペンタン類 | |
| JP3533567B2 (ja) | 置換アニリンから置換キノリンを製造する新規合成法 | |
| US4866197A (en) | Production of N-((2-alkoxy-6-methoxy-5-(trifluoromethyl)-1-naphthalenyl)carbonyl)-N-methylglycine esters | |
| BE858864A (fr) | Nouveaux esters d'acides phenyl- et pyridine-3-carboxylique et procede permettant leur preparation | |
| EP1019376A1 (fr) | Derives de pyridone, leur preparation et leur utilisation comme intermediaires de synthese | |
| FR2727410A1 (fr) | Chlorures de sulfonyles, leur preparation et leur utilisation comme intermediaires de synthese | |
| US6495713B2 (en) | Synthesis of ketosulfone esters | |
| JPH03215472A (ja) | 新規な4―置換―3,5―ジメチルピコリン酸化合物およびその製造方法 |