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Priority claimed from DE19873722775external-prioritypatent/DE3722775A1/en
Application filed by Lts Lohmann Therapie-Systeme Gmbh & Co. KgfiledCriticalLts Lohmann Therapie-Systeme Gmbh & Co. Kg
Publication of SI8811326ApublicationCriticalpatent/SI8811326A/en
Publication of SI8811326BpublicationCriticalpatent/SI8811326B/en
PATENTNI ZAHTEVKI 1. Terapevtski sistem, ki deluje skozi kožo, za nanašanje aktivnih snovi na kožo, z oporno plastjo (10), obrnjeno stran od kože, shrambo (14) aktivne snovi, napravo za uravnavanje prenosa aktivne snovi, ki uravnava prenos aktivne snovi skozi sistem, in pritrjevalno napravo (19) za pritrditev terapevtskega sistema na kožo, označen s tem, da je shramba aktivne snovi večkomomi sistem, v katerem imajo posamezne komore (14) eno ali več aktivnih snovi in so vsaj delno povezane med seboj s kanali (15), pri čemer je notranji premer kanalov (15) med komorami (14) takšen, da dopušča, da aktivna snov teče skozi le ob aplikaciji tlaka.A therapeutic system acting through the skin for applying the active substances to the skin with a support layer (10), away from the skin, a storage (14) of the active substance, a device for regulating the transmission of an active substance that regulates the transmission of the active substance through the system, and an attachment device (19) for fastening the therapeutic system to the skin, characterized in that the storage of the active substance is a multicomponent system in which the individual chambers (14) have one or more active substances and are at least partially connected to one another with the channels (15), wherein the inner diameter of the channels (15) between the chambers (14) is such that it allows the active substance to flow through only at the application of the pressure.2. Terapevtski sistem, ki deluje skozi kožo, po zahtevku 1, označen s tem, da ima vsaka komora (14) v danem primeru različne naprave za uravnavanje prenosa aktivne snovi.A therapeutic system acting through the skin according to claim 1, characterized in that each chamber (14) has, in a given case, different devices for regulating the transmission of the active substance.3. Terapevtski sistem, ki deluje skozi kožo, po enem od prejšnjih zahtekov, označen s tem, da so komore (14) razporejene v eno ali več enakih ali različnih matric (12,12’) za razporeditev aktivne snovi.A therapeutic system acting through the skin according to one of the preceding claims, characterized in that the chambers (14) are arranged in one or more identical or different matrices (12, 12 ') for the arrangement of the active substance.4. Terapevtski sistem, ki deluje skozi kožo, po enem od prejšnjih zahtevkov, označen s tem, da ima neprekinjeno ali prekinjeno lepljivo plast (19) na strani kože kot pritrjevalno napravo za kožo.A therapeutic system acting through the skin according to one of the preceding claims, characterized in that the continuous or discontinuous adhesive layer (19) has on the skin side of the skin as a skin fixing device.5. Terapevtski sistem, ki deluje skozi kožo, po enem od prejšnjih zahtevkov, označen s tem, da ima nadalje eno ali več lepljivih plasti med oporno plastjo (10) in pritrjevalno napravo (19).A therapeutic system acting through the skin according to one of the preceding claims, characterized in that it further comprises one or more adhesive layers between the support layer (10) and the fixing device (19).6. Terapevtski sistem, ki deluje skozi kožo, po enem od prejšnjih zahtevkov, označen s tem, da je aktivna snov prisotna v tekoči obliki ali v raztopini.A therapeutic system acting through the skin according to one of the preceding claims, characterized in that the active substance is present in the liquid form or in the solution.7. Terapevtski sistem, ki deluje skozi kožo, po enem od prejšnjih zahtevkov, označen s tem, da ima večkomorni sistem med posameznimi komorami (14) aktivne snovi in v danem primeru v oporni plasti (10) in drugih plasteh prelomne linije (17). zA therapeutic system acting through the skin according to one of the preceding claims, characterized in that the multi-chamber system has, between the individual chambers (14) of the active substance and optionally in the support layer (10) and the other layers of the breaking line (17) . z8. Terapevtski sistem, ki deluje skozi kožo, po enem od prejšnjih zahtevkov, označen s tem, da večkomorni sistem predstavlja sistem s kanali (15).A therapeutic system acting through the skin according to one of the preceding claims, characterized in that the multi-chamber system is a system with channels (15).9. Terapevtski sistem, ki deluje skozi kožo, po enem od prejšnjih zahtevkov, označen s tem, da so komore (14) razporejene na različnih vertikalnih nivojih obliža, v danem primeru v različnih matricah za razpodelitev. Za LTS LOHMANN Therapie-Systeme GmbH & Co. KG: irA therapeutic system acting through the skin according to one of the preceding claims, characterized in that the chambers (14) are arranged at different vertical levels of the patch, optionally in different dispensing matrices. For LTS LOHMANN Therapie-Systeme GmbH & Co. KG: ir
SI8811326A1987-07-091988-07-08Therapeutic system acting through the skin.
SI8811326B
(en)
Film-forming, pharmaceutical vehicles for application of medicaments to nails, pharmaceutical compositions based on those vehicles, and methods of using same.
Biological cells externally modified for controlled release,in the spleen and/or liver,of pharmaceutically active substances comprised therein,their preparation and pharmaceutical compositions containing them