SI3947375T1 - Imidazolonilkinolinske spojine in terapevtske uporabe le-teh - Google Patents
Imidazolonilkinolinske spojine in terapevtske uporabe le-tehInfo
- Publication number
- SI3947375T1 SI3947375T1 SI202030449T SI202030449T SI3947375T1 SI 3947375 T1 SI3947375 T1 SI 3947375T1 SI 202030449 T SI202030449 T SI 202030449T SI 202030449 T SI202030449 T SI 202030449T SI 3947375 T1 SI3947375 T1 SI 3947375T1
- Authority
- SI
- Slovenia
- Prior art keywords
- imidazolonylquinoline
- compounds
- therapeutic uses
- therapeutic
- imidazolonylquinoline compounds
- Prior art date
Links
- BAHVJMJZUDCTPT-UHFFFAOYSA-N 4-quinolin-2-ylimidazol-2-one Chemical class O=C1N=CC(C=2N=C3C=CC=CC3=CC=2)=N1 BAHVJMJZUDCTPT-UHFFFAOYSA-N 0.000 title 1
- 230000001225 therapeutic effect Effects 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
- C07D471/04—Ortho-condensed systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/47—Quinolines; Isoquinolines
- A61K31/4738—Quinolines; Isoquinolines ortho- or peri-condensed with heterocyclic ring systems
- A61K31/4745—Quinolines; Isoquinolines ortho- or peri-condensed with heterocyclic ring systems condensed with ring systems having nitrogen as a ring hetero atom, e.g. phenantrolines
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A61P35/02—Antineoplastic agents specific for leukemia
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07B—GENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
- C07B2200/00—Indexing scheme relating to specific properties of organic compounds
- C07B2200/05—Isotopically modified compounds, e.g. labelled
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07B—GENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
- C07B2200/00—Indexing scheme relating to specific properties of organic compounds
- C07B2200/13—Crystalline forms, e.g. polymorphs
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Pharmacology & Pharmacy (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Epidemiology (AREA)
- Hematology (AREA)
- Oncology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP19165664 | 2019-03-27 | ||
| EP20715020.2A EP3947375B1 (en) | 2019-03-27 | 2020-03-25 | Imidazolonylquinoline compounds and therapeutic uses thereof |
| PCT/EP2020/058425 WO2020193660A1 (en) | 2019-03-27 | 2020-03-25 | Imidazolonylquinoline compounds and therapeutic uses thereof |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| SI3947375T1 true SI3947375T1 (sl) | 2024-08-30 |
Family
ID=65995619
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| SI202030449T SI3947375T1 (sl) | 2019-03-27 | 2020-03-25 | Imidazolonilkinolinske spojine in terapevtske uporabe le-teh |
Country Status (23)
| Country | Link |
|---|---|
| US (2) | US12344604B2 (sl) |
| EP (1) | EP3947375B1 (sl) |
| JP (1) | JP2022526926A (sl) |
| KR (1) | KR20210143263A (sl) |
| CN (2) | CN113614083B (sl) |
| AU (2) | AU2020247451B2 (sl) |
| BR (1) | BR112021018950A2 (sl) |
| CA (1) | CA3134874A1 (sl) |
| DK (1) | DK3947375T3 (sl) |
| ES (1) | ES2984074T3 (sl) |
| FI (1) | FI3947375T3 (sl) |
| HR (1) | HRP20240650T1 (sl) |
| HU (1) | HUE066895T2 (sl) |
| IL (1) | IL286079A (sl) |
| LT (1) | LT3947375T (sl) |
| MX (1) | MX2021011389A (sl) |
| PL (1) | PL3947375T3 (sl) |
| PT (1) | PT3947375T (sl) |
| RS (1) | RS65518B1 (sl) |
| SG (1) | SG11202110480YA (sl) |
| SI (1) | SI3947375T1 (sl) |
| WO (1) | WO2020193660A1 (sl) |
| ZA (1) | ZA202108263B (sl) |
Families Citing this family (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| AU2021346097A1 (en) * | 2020-09-18 | 2023-03-09 | Merck Patent Gmbh | Pharmaceutical preparation |
| KR20240109981A (ko) * | 2021-10-06 | 2024-07-12 | 미라티 테라퓨틱스, 인크. | 거울상이성질체의 분리 방법（methods for separation of enantiomers） |
| KR102839730B1 (ko) | 2021-10-26 | 2025-07-28 | 주식회사 엘지에너지솔루션 | 이차전지의 저전압 불량 판정 시스템 및 이를 이용한 이차전지의 불량 판정 방법 |
| CN115716829B (zh) * | 2022-11-13 | 2024-05-31 | 药康众拓(江苏)医药科技有限公司 | 一种喹啉并咪唑酮联氘代吡唑类化合物及其应用 |
| WO2025157979A1 (en) | 2024-01-26 | 2025-07-31 | Merck Patent Gmbh | Synthesis route for preparing 8-(1,3-dimethyl-1h-pyrazol-4-yl)-1-(sa)-(3-fluoro-5-methoxy-pyridin-4-yl)-7-methoxy-3-methyl-1,3-dihydro-imidazo[4,5-c]quinolin-2-one |
| WO2025217307A1 (en) | 2024-04-09 | 2025-10-16 | Revolution Medicines, Inc. | Methods for predicting response to a ras(on) inhibitor and combination therapies |
| WO2025240847A1 (en) | 2024-05-17 | 2025-11-20 | Revolution Medicines, Inc. | Ras inhibitors |
Family Cites Families (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| UA75622C2 (en) | 2000-12-08 | 2006-05-15 | 3M Innovative Properties Co | Aryl ether substituted imidazoquinolines, pharmaceutical composition based thereon |
| US10531049B2 (en) | 2015-03-31 | 2020-01-07 | Nec Corporation | Methods and systems for scheduling of sensing platform nodes |
| CA2981365A1 (en) * | 2015-04-02 | 2016-10-06 | Merck Patent Gmbh | Imidazolonylquinolines and the use thereof as atm kinase inhibitors |
| CA2981364C (en) | 2015-04-09 | 2019-03-19 | Husqvarna Ab | Spray head and spraying apparatus |
| CN108752336B (zh) * | 2018-05-10 | 2021-06-04 | 常州润诺生物科技有限公司 | 咪唑并喹啉类衍生物及其用途 |
-
2020
- 2020-03-25 CN CN202080025075.9A patent/CN113614083B/zh active Active
- 2020-03-25 SI SI202030449T patent/SI3947375T1/sl unknown
- 2020-03-25 RS RS20240560A patent/RS65518B1/sr unknown
- 2020-03-25 PT PT207150202T patent/PT3947375T/pt unknown
- 2020-03-25 BR BR112021018950A patent/BR112021018950A2/pt unknown
- 2020-03-25 ES ES20715020T patent/ES2984074T3/es active Active
- 2020-03-25 EP EP20715020.2A patent/EP3947375B1/en active Active
- 2020-03-25 KR KR1020217034224A patent/KR20210143263A/ko active Pending
- 2020-03-25 HR HRP20240650TT patent/HRP20240650T1/hr unknown
- 2020-03-25 JP JP2021557193A patent/JP2022526926A/ja active Pending
- 2020-03-25 LT LTEPPCT/EP2020/058425T patent/LT3947375T/lt unknown
- 2020-03-25 FI FIEP20715020.2T patent/FI3947375T3/fi active
- 2020-03-25 WO PCT/EP2020/058425 patent/WO2020193660A1/en not_active Ceased
- 2020-03-25 MX MX2021011389A patent/MX2021011389A/es unknown
- 2020-03-25 CA CA3134874A patent/CA3134874A1/en active Pending
- 2020-03-25 HU HUE20715020A patent/HUE066895T2/hu unknown
- 2020-03-25 SG SG11202110480YA patent/SG11202110480YA/en unknown
- 2020-03-25 US US17/442,703 patent/US12344604B2/en active Active
- 2020-03-25 AU AU2020247451A patent/AU2020247451B2/en not_active Expired - Fee Related
- 2020-03-25 PL PL20715020.2T patent/PL3947375T3/pl unknown
- 2020-03-25 CN CN202410934651.1A patent/CN118878534A/zh active Pending
- 2020-03-25 DK DK20715020.2T patent/DK3947375T3/da active
-
2021
- 2021-09-02 IL IL286079A patent/IL286079A/en unknown
- 2021-10-26 ZA ZA2021/08263A patent/ZA202108263B/en unknown
-
2025
- 2025-01-16 US US19/023,634 patent/US20250188080A1/en active Pending
- 2025-04-17 AU AU2025202754A patent/AU2025202754A1/en active Pending
Also Published As
| Publication number | Publication date |
|---|---|
| CA3134874A1 (en) | 2020-10-01 |
| KR20210143263A (ko) | 2021-11-26 |
| FI3947375T3 (fi) | 2024-05-30 |
| ZA202108263B (en) | 2024-04-24 |
| WO2020193660A1 (en) | 2020-10-01 |
| LT3947375T (lt) | 2024-06-10 |
| MX2021011389A (es) | 2021-10-13 |
| US12344604B2 (en) | 2025-07-01 |
| PL3947375T3 (pl) | 2024-08-05 |
| SG11202110480YA (en) | 2021-10-28 |
| HUE066895T2 (hu) | 2024-09-28 |
| JP2022526926A (ja) | 2022-05-27 |
| EP3947375B1 (en) | 2024-04-03 |
| HRP20240650T1 (hr) | 2024-08-02 |
| US20250188080A1 (en) | 2025-06-12 |
| AU2025202754A1 (en) | 2025-05-08 |
| RS65518B1 (sr) | 2024-06-28 |
| BR112021018950A2 (pt) | 2022-01-18 |
| AU2020247451A1 (en) | 2021-11-18 |
| US20220144828A1 (en) | 2022-05-12 |
| CN113614083B (zh) | 2024-08-27 |
| EP3947375A1 (en) | 2022-02-09 |
| CN118878534A (zh) | 2024-11-01 |
| AU2020247451B2 (en) | 2025-04-10 |
| ES2984074T3 (es) | 2024-10-28 |
| DK3947375T3 (da) | 2024-05-21 |
| PT3947375T (pt) | 2024-05-28 |
| IL286079A (en) | 2021-10-31 |
| CN113614083A (zh) | 2021-11-05 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| IL285178A (en) | Compounds and uses thereof | |
| IL282487A (en) | Tyk2 inhibitors and uses thereof | |
| IL279897A (en) | Fusosome compositions and uses thereof | |
| IL284835A (en) | Pharmaceutical combination comprising tno155 and ribociclib | |
| SI3658557T1 (sl) | Zaviralci TYK2 in njihova uporaba | |
| IL277640A (en) | Humanized bcma antibody and bcma-car-t cells | |
| SI3947375T1 (sl) | Imidazolonilkinolinske spojine in terapevtske uporabe le-teh | |
| IL282090A (en) | Tyk2 inhibitors and uses thereof | |
| DK3737765T4 (da) | Forstærkede immunceller med dobbelt shrna og sammensætning dermed | |
| DK3283106T3 (da) | Terapeutiske antistoffer og anvendelser deraf | |
| DK3357513T3 (da) | Farmaceutisk sammensætning og anvendelse deraf | |
| IL278122B1 (en) | Pteridinone compounds and uses thereof | |
| DK3256218T3 (da) | Kdm1a-hæmmer og anvendelse deraf i terapi | |
| LT3452485T (lt) | Arginazės inhibitoriai ir jų terapinis taikymas | |
| MA41794A (fr) | Agents thérapeutiques modifiés et compositions associées | |
| EP3310376A4 (en) | MODIFIED THERAPEUTIC AGENTS AND COMPOSITIONS THEREOF | |
| EP3893945A4 (en) | CROMOGLYC ESTERS AND THEIR USES | |
| EP3781576C0 (en) | BORONIC ACID DERIVATIVES AND THEIR THERAPEUTIC USES | |
| IL284053A (en) | New compounds and their use in therapy | |
| DK3532059T3 (da) | Kombinationsterapi med bromdomæne- og ekstraterminal proteinhæmmer | |
| PL3768284T3 (pl) | Kompozycje z fageliny entrecoccus do zastosowania w terapii | |
| IL285118A (en) | Compounds and uses thereof | |
| DK3606926T3 (da) | Heteroaromatiske forbindelser anvendelige i terapi | |
| IL284514A (en) | Halo-allylamine compounds and use thereof | |
| DK3615502T3 (da) | Terapeutiske forbindelser og fremgangsmåder |