SI3500306T1 - Trojna kombinacija histamin-3 receptor inverznega agonista, inhibitorjev acetilholinesteraze in NMDA receptor antagonista - Google Patents
Trojna kombinacija histamin-3 receptor inverznega agonista, inhibitorjev acetilholinesteraze in NMDA receptor antagonistaInfo
- Publication number
- SI3500306T1 SI3500306T1 SI201730420T SI201730420T SI3500306T1 SI 3500306 T1 SI3500306 T1 SI 3500306T1 SI 201730420 T SI201730420 T SI 201730420T SI 201730420 T SI201730420 T SI 201730420T SI 3500306 T1 SI3500306 T1 SI 3500306T1
- Authority
- SI
- Slovenia
- Prior art keywords
- histamine
- inverse agonist
- acetylcholinesterase inhibitor
- triple combination
- receptor antagonist
- Prior art date
Links
- 229940100578 Acetylcholinesterase inhibitor Drugs 0.000 title 1
- 229940099433 NMDA receptor antagonist Drugs 0.000 title 1
- 239000000544 cholinesterase inhibitor Substances 0.000 title 1
- 239000003703 n methyl dextro aspartic acid receptor blocking agent Substances 0.000 title 1
- 239000002469 receptor inverse agonist Substances 0.000 title 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/535—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one oxygen as the ring hetero atoms, e.g. 1,2-oxazines
- A61K31/5375—1,4-Oxazines, e.g. morpholine
- A61K31/5377—1,4-Oxazines, e.g. morpholine not condensed and containing further heterocyclic rings, e.g. timolol
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/13—Amines
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
- A61K31/19—Carboxylic acids, e.g. valproic acid
- A61K31/195—Carboxylic acids, e.g. valproic acid having an amino group
- A61K31/197—Carboxylic acids, e.g. valproic acid having an amino group the amino and the carboxyl groups being attached to the same acyclic carbon chain, e.g. gamma-aminobutyric acid [GABA], beta-alanine, epsilon-aminocaproic acid or pantothenic acid
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/21—Esters, e.g. nitroglycerine, selenocyanates
- A61K31/27—Esters, e.g. nitroglycerine, selenocyanates of carbamic or thiocarbamic acids, meprobamate, carbachol, neostigmine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/445—Non condensed piperidines, e.g. piperocaine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/55—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
- A61P25/16—Anti-Parkinson drugs
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2300/00—Mixtures or combinations of active ingredients, wherein at least one active ingredient is fully defined in groups A61K31/00 - A61K41/00
Landscapes
- Health & Medical Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Psychiatry (AREA)
- Hospice & Palliative Care (AREA)
- Emergency Medicine (AREA)
- Psychology (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| IN201641028165 | 2016-08-18 | ||
| EP17764658.5A EP3500306B1 (en) | 2016-08-18 | 2017-08-14 | Triple combination of histamine-3 receptor inverse agonists, acetylcholinesterase inhibitors and nmda receptor antagonist |
| PCT/IB2017/054939 WO2018033848A1 (en) | 2016-08-18 | 2017-08-14 | Triple combination of histamine-3 receptor inverse agonists, acetylcholinesterase inhibitors and nmda receptor antagonist |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| SI3500306T1 true SI3500306T1 (sl) | 2020-11-30 |
Family
ID=59829422
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| SI201730420T SI3500306T1 (sl) | 2016-08-18 | 2017-08-14 | Trojna kombinacija histamin-3 receptor inverznega agonista, inhibitorjev acetilholinesteraze in NMDA receptor antagonista |
Country Status (27)
| Country | Link |
|---|---|
| US (1) | US20190336509A1 (sl) |
| EP (1) | EP3500306B1 (sl) |
| JP (1) | JP6734469B2 (sl) |
| KR (1) | KR102040639B1 (sl) |
| CN (1) | CN109562180B (sl) |
| AU (1) | AU2017311666B2 (sl) |
| BR (1) | BR112019002637A2 (sl) |
| CA (1) | CA3033050C (sl) |
| CY (1) | CY1123522T1 (sl) |
| DK (1) | DK3500306T3 (sl) |
| EA (1) | EA036480B1 (sl) |
| ES (1) | ES2818898T3 (sl) |
| HR (1) | HRP20201511T1 (sl) |
| HU (1) | HUE051474T2 (sl) |
| IL (1) | IL264405B (sl) |
| LT (1) | LT3500306T (sl) |
| MA (1) | MA45988B1 (sl) |
| MD (1) | MD3500306T2 (sl) |
| MX (1) | MX377517B (sl) |
| PL (1) | PL3500306T3 (sl) |
| PT (1) | PT3500306T (sl) |
| RS (1) | RS60832B1 (sl) |
| SG (1) | SG11201900680PA (sl) |
| SI (1) | SI3500306T1 (sl) |
| SM (1) | SMT202000525T1 (sl) |
| WO (1) | WO2018033848A1 (sl) |
| ZA (1) | ZA201900436B (sl) |
Families Citing this family (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| SMT202500075T1 (it) * | 2018-05-31 | 2025-05-12 | Suven Life Sciences Ltd | Metodo di trattamento con un agonista inverso del recettore dell’istamina-3 |
Family Cites Families (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| AP3340A (en) * | 2011-02-23 | 2015-07-31 | Suven Life Science Ltd | Novel compounds as histamine H3 receptor ligands |
| FR2974729B1 (fr) * | 2011-05-02 | 2013-04-19 | Servier Lab | Nouvelle association entre le 4-{3-[cis-hexahydrocyclopenta[c]pyrrol-2(1h)-yl]propoxy}benzamide et un inhibiteur de l'acetylcholinesterase et les compositions pharmaceutiques qui la contiennent |
| HUP1300139A2 (en) * | 2013-03-06 | 2014-09-29 | Richter Gedeon Nyrt | Phenoxypiperidine h3 antagonists |
-
2017
- 2017-08-14 US US16/319,668 patent/US20190336509A1/en not_active Abandoned
- 2017-08-14 JP JP2019506623A patent/JP6734469B2/ja not_active Expired - Fee Related
- 2017-08-14 MD MDE20190713T patent/MD3500306T2/ro not_active IP Right Cessation
- 2017-08-14 EA EA201990481A patent/EA036480B1/ru unknown
- 2017-08-14 AU AU2017311666A patent/AU2017311666B2/en not_active Ceased
- 2017-08-14 KR KR1020197007052A patent/KR102040639B1/ko not_active Expired - Fee Related
- 2017-08-14 HR HRP20201511TT patent/HRP20201511T1/hr unknown
- 2017-08-14 WO PCT/IB2017/054939 patent/WO2018033848A1/en not_active Ceased
- 2017-08-14 PT PT177646585T patent/PT3500306T/pt unknown
- 2017-08-14 SI SI201730420T patent/SI3500306T1/sl unknown
- 2017-08-14 EP EP17764658.5A patent/EP3500306B1/en active Active
- 2017-08-14 CA CA3033050A patent/CA3033050C/en active Active
- 2017-08-14 DK DK17764658.5T patent/DK3500306T3/da active
- 2017-08-14 PL PL17764658T patent/PL3500306T3/pl unknown
- 2017-08-14 BR BR112019002637A patent/BR112019002637A2/pt not_active IP Right Cessation
- 2017-08-14 HU HUE17764658A patent/HUE051474T2/hu unknown
- 2017-08-14 CN CN201780048908.1A patent/CN109562180B/zh not_active Expired - Fee Related
- 2017-08-14 MX MX2019001698A patent/MX377517B/es active IP Right Grant
- 2017-08-14 SM SM20200525T patent/SMT202000525T1/it unknown
- 2017-08-14 SG SG11201900680PA patent/SG11201900680PA/en unknown
- 2017-08-14 ES ES17764658T patent/ES2818898T3/es active Active
- 2017-08-14 MA MA45988A patent/MA45988B1/fr unknown
- 2017-08-14 RS RS20201135A patent/RS60832B1/sr unknown
- 2017-08-14 LT LTEP17764658.5T patent/LT3500306T/lt unknown
-
2019
- 2019-01-22 ZA ZA2019/00436A patent/ZA201900436B/en unknown
- 2019-01-22 IL IL264405A patent/IL264405B/en active IP Right Grant
-
2020
- 2020-09-22 CY CY20201100891T patent/CY1123522T1/el unknown
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